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Journal of clinical oncology, ISSN 1527-7755, 08/2013, Volume 31, Issue 23, pp. 2927 - 2935
Purpose Reports detailing the prognostic impact of TP53 mutations in medulloblastoma offer conflicting conclusions. We resolve this issue through the inclusion... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Prognosis | Humans | Middle Aged | Child, Preschool | Infant | Male | Gene Expression Profiling | Cerebellar Neoplasms - genetics | Young Adult | Genes, p53 | Medulloblastoma - pathology | Adolescent | Adult | Female | Cerebellar Neoplasms - pathology | Mutation | Medulloblastoma - genetics | Child | Index Medicus | Pedi4 | ORIGINAL REPORTS
Journal Article
Cancer cell, ISSN 1535-6108, 05/2015, Volume 27, Issue 5, pp. 728 - 743
Ependymal tumors across age groups are currently classified and graded solely by histopathology. It is, however, commonly accepted that this classification... 
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Tumors | Index Medicus
Journal Article
by Sturm, Dominik and Witt, Hendrik and Hovestadt, Volker and Khuong-Quang, Dong-Anh and Jones, David T.W and Konermann, Carolin and Pfaff, Elke and Tönjes, Martje and Sill, Martin and Bender, Sebastian and Kool, Marcel and Zapatka, Marc and Becker, Natalia and Zucknick, Manuela and Hielscher, Thomas and Liu, Xiao-Yang and Fontebasso, Adam M and Ryzhova, Marina and Albrecht, Steffen and Jacob, Karine and Wolter, Marietta and Ebinger, Martin and Schuhmann, Martin U and van Meter, Timothy and Frühwald, Michael C and Hauch, Holger and Pekrun, Arnulf and Radlwimmer, Bernhard and Niehues, Tim and von Komorowski, Gregor and Dürken, Matthias and Kulozik, Andreas E and Madden, Jenny and Donson, Andrew and Foreman, Nicholas K and Drissi, Rachid and Fouladi, Maryam and Scheurlen, Wolfram and von Deimling, Andreas and Monoranu, Camelia and Roggendorf, Wolfgang and Herold-Mende, Christel and Unterberg, Andreas and Kramm, Christof M and Felsberg, Jörg and Hartmann, Christian and Wiestler, Benedikt and Wick, Wolfgang and Milde, Till and Witt, Olaf and Lindroth, Anders M and Schwartzentruber, Jeremy and Faury, Damien and Fleming, Adam and Zakrzewska, Magdalena and Liberski, Pawel P and Zakrzewski, Krzysztof and Hauser, Peter and Garami, Miklos and Klekner, Almos and Bognar, Laszlo and Morrissy, Sorana and Cavalli, Florence and Taylor, Michael D and van Sluis, Peter and Koster, Jan and Versteeg, Rogier and Volckmann, Richard and Mikkelsen, Tom and Aldape, Kenneth and Reifenberger, Guido and Collins, V. Peter and Majewski, Jacek and Korshunov, Andrey and Lichter, Peter and Plass, Christoph and Jabado, Nada and Pfister, Stefan M
Cancer cell, ISSN 1535-6108, 10/2012, Volume 22, Issue 4, pp. 425 - 437
Journal Article
by Sturm, Dominik and Orr, Brent A and Toprak, Umut H and Hovestadt, Volker and Jones, David T.W and Capper, David and Sill, Martin and Buchhalter, Ivo and Northcott, Paul A and Leis, Irina and Ryzhova, Marina and Koelsche, Christian and Pfaff, Elke and Allen, Sariah J and Balasubramanian, Gnanaprakash and Worst, Barbara C and Pajtler, Kristian W and Brabetz, Sebastian and Johann, Pascal D and Sahm, Felix and Reimand, Jüri and Mackay, Alan and Carvalho, Diana M and Remke, Marc and Phillips, Joanna J and Perry, Arie and Cowdrey, Cynthia and Drissi, Rachid and Fouladi, Maryam and Giangaspero, Felice and Łastowska, Maria and Grajkowska, Wiesława and Scheurlen, Wolfram and Pietsch, Torsten and Hagel, Christian and Gojo, Johannes and Lötsch, Daniela and Berger, Walter and Slavc, Irene and Haberler, Christine and Jouvet, Anne and Holm, Stefan and Hofer, Silvia and Prinz, Marco and Keohane, Catherine and Fried, Iris and Mawrin, Christian and Scheie, David and Mobley, Bret C and Schniederjan, Matthew J and Santi, Mariarita and Buccoliero, Anna M and Dahiya, Sonika and Kramm, Christof M and von Bueren, André O and von Hoff, Katja and Rutkowski, Stefan and Herold-Mende, Christel and Frühwald, Michael C and Milde, Till and Hasselblatt, Martin and Wesseling, Pieter and Rößler, Jochen and Schüller, Ulrich and Ebinger, Martin and Schittenhelm, Jens and Frank, Stephan and Grobholz, Rainer and Vajtai, Istvan and Hans, Volkmar and Schneppenheim, Reinhard and Zitterbart, Karel and Collins, V. Peter and Aronica, Eleonora and Varlet, Pascale and Puget, Stephanie and Dufour, Christelle and Grill, Jacques and Figarella-Branger, Dominique and Wolter, Marietta and Schuhmann, Martin U and Shalaby, Tarek and Grotzer, Michael and van Meter, Timothy and Monoranu, Camelia-Maria and Felsberg, Jörg and Reifenberger, Guido and Snuderl, Matija and Forrester, Lynn Ann and Koster, Jan and Versteeg, Rogier and Volckmann, Richard and van Sluis, Peter and Wolf, Stephan and Mikkelsen, Tom and Gajjar, Amar and Aldape, Kenneth and Moore, Andrew S and Taylor, Michael D and Jones, Chris and ...
Cell (Cambridge), ISSN 0092-8674, 02/2016, Volume 164, Issue 5, pp. 1060 - 1072
Journal Article
Cancer cell, ISSN 1535-6108, 11/2013, Volume 24, Issue 5, pp. 660 - 672
Journal Article
by Kool, Marcel and Jones, David T.W and Jäger, Natalie and Northcott, Paul A and Pugh, Trevor J and Hovestadt, Volker and Piro, Rosario M and Esparza, L. Adriana and Markant, Shirley L and Remke, Marc and Milde, Till and Bourdeaut, Franck and Ryzhova, Marina and Sturm, Dominik and Pfaff, Elke and Stark, Sebastian and Hutter, Sonja and Şeker-Cin, Huriye and Johann, Pascal and Bender, Sebastian and Schmidt, Christin and Rausch, Tobias and Shih, David and Reimand, Jüri and Sieber, Laura and Wittmann, Andrea and Linke, Linda and Witt, Hendrik and Weber, Ursula D and Zapatka, Marc and König, Rainer and Beroukhim, Rameen and Bergthold, Guillaume and van Sluis, Peter and Volckmann, Richard and Koster, Jan and Versteeg, Rogier and Schmidt, Sabine and Wolf, Stephan and Lawerenz, Chris and Bartholomae, Cynthia C and von Kalle, Christof and Unterberg, Andreas and Herold-Mende, Christel and Hofer, Silvia and Kulozik, Andreas E and von Deimling, Andreas and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Hasselblatt, Martin and Crawford, John R and Grant, Gerald A and Jabado, Nada and Perry, Arie and Cowdrey, Cynthia and Croul, Sydney and Zadeh, Gelareh and Korbel, Jan O and Doz, Francois and Delattre, Olivier and Bader, Gary D and McCabe, Martin G and Collins, V. Peter and Kieran, Mark W and Cho, Yoon-Jae and Pomeroy, Scott L and Witt, Olaf and Brors, Benedikt and Taylor, Michael D and Schüller, Ulrich and Korshunov, Andrey and Eils, Roland and Wechsler-Reya, Robert J and Lichter, Peter and Pfister, Stefan M and on behalf of the ICGC PedBrain Tumor Project and ICGC PedBrain Tumor Project
Cancer cell, ISSN 1535-6108, 03/2014, Volume 25, Issue 3, pp. 393 - 405
Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven medulloblastoma (SHH-MB). Clinical response is highly variable. To... 
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasm Transplantation | Oncogene Proteins - genetics | Humans | Zinc Finger Protein Gli2 | Child, Preschool | Molecular Sequence Data | Infant | Male | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Biphenyl Compounds - therapeutic use | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Young Adult | Telomerase - genetics | Hedgehog Proteins - genetics | Base Sequence | Smoothened Receptor | Adult | Female | N-Myc Proto-Oncogene Protein | Patched Receptors | Medulloblastoma - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Child | Pyridines - therapeutic use | Cerebellar Neoplasms - drug therapy | Repressor Proteins - genetics | DNA Copy Number Variations - genetics | Signal Transduction - genetics | Cerebellar Neoplasms - genetics | Mice, SCID | Phosphatidylinositol 3-Kinases - genetics | DEAD-box RNA Helicases - genetics | Drug Resistance, Neoplasm - genetics | Animals | Adolescent | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice, Inbred NOD | High-Throughput Nucleotide Sequencing | Mice | Receptors, G-Protein-Coupled - genetics | Medulloblastoma - drug therapy | Kruppel-Like Transcription Factors - genetics | Patched-1 Receptor | Receptors, Cell Surface - genetics | Genetic aspects | Nucleotide sequencing | Analysis | Medulloblastoma | Genomics | DNA sequencing | Index Medicus
Journal Article
Cell (Cambridge), ISSN 0092-8674, 01/2012, Volume 148, Issue 1-2, pp. 59 - 71
Journal Article