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Journal of clinical investigation, ISSN 0021-9738, 2011, Volume 121, Issue 6, pp. 2254 - 2263
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, pp. 131 - 138
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 6/2007, Volume 195, Issue 11, pp. 1718 - 1725
Background. We investigated CD4⁺ memory T cell responses to influenza virus (FLU), respiratory syncytial virus (RSV), and nontypeable Haemophilus influenzae... 
T lymphocytes | Human respiratory syncytial virus | Antigens | Pathogens | Lungs | Memory | Viruses | Infections | Chronic obstructive pulmonary disease | Pathogenesis and Host Response | Blood | CHRONIC-BRONCHITIS | PRIMARY CYTOMEGALOVIRUS-INFECTION | INFECTIOUS DISEASES | NONTYPABLE HAEMOPHILUS-INFLUENZAE | OUTER-MEMBRANE PROTEIN | ACUTE EXACERBATIONS | AIRWAY INFLAMMATION | SYNCYTIAL VIRUS | EX-VIVO | OBSTRUCTIVE-PULMONARY-DISEASE | VACCINE ANTIGEN | Lymphocyte Activation | Humans | Middle Aged | Influenza, Human - complications | CD4-Positive T-Lymphocytes - classification | Pulmonary Disease, Chronic Obstructive - complications | Haemophilus Infections - complications | Respiratory Syncytial Virus Infections - immunology | Orthomyxoviridae - immunology | CD4-Positive T-Lymphocytes - immunology | Respiratory Syncytial Virus, Human - immunology | Leukocytes, Mononuclear - immunology | Haemophilus Infections - microbiology | Haemophilus influenzae - immunology | Influenza, Human - virology | Aged | Haemophilus Infections - immunology | Pulmonary Disease, Chronic Obstructive - immunology | Respiratory Syncytial Virus Infections - virology | Immunologic Memory - immunology | Lung - immunology | Influenza, Human - immunology | Influenza viruses | Physiological aspects | Respiratory syncytial virus | Research | CD4 lymphocytes | Hemophilus influenzae | Index Medicus | Abridged Index Medicus
Journal Article
Respiratory research, ISSN 1465-9921, 2010, Volume 11, Issue 1, pp. 66 - 66
The budesonide/formoterol combination is successfully used for fast relief of asthma symptoms in addition to its use as maintenance therapy. The temporarily... 
MAINTENANCE | ADENOSINE 5'-MONOPHOSPHATE | FLUTICASONE PROPIONATE | AIRWAY RESPONSIVENESS | RESPIRATORY SYSTEM | LUNG-FUNCTION | RELIEVER THERAPY | BUDESONIDE | INDUCED BRONCHOCONSTRICTION | SINGLE INHALER | ALLERGEN CHALLENGE | Bronchodilator Agents - therapeutic use | Formoterol Fumarate | Glucocorticoids - administration & dosage | Glucocorticoids - therapeutic use | Bronchodilator Agents - administration & dosage | Humans | Middle Aged | Bronchial Provocation Tests | Male | Ethanolamines - administration & dosage | Forced Expiratory Volume | Young Adult | Bronchoconstrictor Agents - administration & dosage | Netherlands | Time Factors | Bronchoconstriction - drug effects | Adrenergic beta-Agonists - administration & dosage | Albuterol - administration & dosage | Adult | Female | Adrenergic beta-Agonists - therapeutic use | Asthma - physiopathology | Double-Blind Method | Administration, Inhalation | Treatment Outcome | Asthma - drug therapy | Cross-Over Studies | Adenosine Monophosphate - administration & dosage | Budesonide - therapeutic use | Albuterol - therapeutic use | Ethanolamines - therapeutic use | Budesonide - administration & dosage | Maximal Midexpiratory Flow Rate | Drug Combinations | Complications and side effects | Patient outcomes | Physiological aspects | Antiasthmatic agents | Dosage and administration | Research | Drug therapy, Combination | Adenylic acid | Drug therapy | Asthma | Prevention | Medical research | Usage | Care and treatment | Corticosteroids | Medicine, Experimental | Inflammation | Albuterol | Comparative analysis | Adenosine | Index Medicus
Journal Article
Nederlands tijdschrift voor geneeskunde, ISSN 0028-2162, 11/2018, Volume 162
Distinguishing between infectious pneumonia and other causes of abnormal X-rays can be challenging. This commentary describes how this distinction can be made... 
Community-Acquired Infections - diagnosis | Diagnosis, Differential | Lung - pathology | Lung Diseases - diagnosis | Humans | Tomography, X-Ray Computed - methods | Female | Male | Lung - diagnostic imaging
Journal Article
Nederlands tijdschrift voor geneeskunde, 11/2018, Volume 162
Journal Article
International journal of cancer, ISSN 0020-7136, 2015, Volume 136, Issue 6, pp. 1434 - 1444
The multikinase inhibitor sorafenib is under clinical investigation for the treatment of many solid tumors, but in most cases, the molecular target responsible... 
AMP‐activated protein kinase | metformin | salicylate | sorafenib | non‐small cell lung cancer | Salicylate | Metformin | AMP-activated protein kinase | Sorafenib | Non-small cell lung cancer | non-small cell lung cancer | DRUG | PROTEIN-KINASE | CHEMOTHERAPY | CELL LUNG-CANCER | LKB1-AMPK PATHWAY | DIABETIC-PATIENTS | BREAST-CANCER | IN-VITRO | METABOLISM | ONCOLOGY | GROWTH | Niacinamide - analogs & derivatives | Lung Neoplasms - drug therapy | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Reactive Oxygen Species - metabolism | Humans | Lung Neoplasms - pathology | Lung Neoplasms - congenital | TOR Serine-Threonine Kinases - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Metformin - pharmacology | Proto-Oncogene Proteins - genetics | Drug Synergism | Xenograft Model Antitumor Assays | AMP-Activated Protein Kinases - physiology | Animals | Calcium-Calmodulin-Dependent Protein Kinase Kinase - antagonists & inhibitors | Cell Line, Tumor | Signal Transduction - physiology | Calcium-Calmodulin-Dependent Protein Kinase Kinase - physiology | Mice | Mice, Inbred BALB C | Phenylurea Compounds - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Niacinamide - pharmacology | Clinical trials | Kinases | Disease control | Lung cancer | Index Medicus | Cancer Therapy
Journal Article
British Journal of Cancer, ISSN 0007-0920, 06/2018, Volume 118, Issue 12, pp. 1586 - 1595
BACKGROUND: Chromosomal instability (CIN) is a common trait of cancer characterised by the continuous gain and loss of chromosomes during mitosis. Excessive... 
BREAST-CANCER | POTENT | MAMMARY-TUMORS | ONCOLOGY | SENSITIVITY | SPINDLE ASSEMBLY CHECKPOINT | TTK | TYROSINE THREONINE KINASE | DERIVATIVES | DISCOVERY | CHROMOSOMAL INSTABILITY | Stability | BRCA1 protein | Copy number | Mitosis | p53 Protein | Mortality | Cell division | Breast cancer | Compounds | Kinases | Genomic instability | Histopathology | Inhibitors | Cell death | Morphology | Mice | Taxanes | Chromosomes | Combinatorial analysis | Tumors | Cancer | Apoptosis | Index Medicus
Journal Article
Thorax, ISSN 0040-6376, 12/2013, Volume 68, Issue 12, pp. 1122 - 1130
Journal Article