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1. Full Text Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells
by Hombrink, Pleun and Helbig, Christina and Backer, Ronald A and Piet, Berber and Oja, Anna E and Stark, Regina and Brasser, Giso and Jongejan, Aldo and Jonkers, René E and Nota, Benjamin and Basak, Onur and Clevers, Hans C and Moerland, Perry D and Amsen, Derk and van Lier, René A. W
Nature immunology, ISSN 1529-2908, 2016, Volume 17, Issue 12, pp. 1467 - 1478
Life Sciences & Biomedicine | Immunology | Science & Technology | Humans | Mice, Inbred C57BL | Middle Aged | Cells, Cultured | Receptor, Notch2 - metabolism | Male | Mice, Transgenic | Receptor, Notch2 - genetics | Integrin alpha Chains - metabolism | Receptor, Notch1 - metabolism | Influenza A Virus, H3N2 Subtype - immunology | CD8-Positive T-Lymphocytes - physiology | Antigens, CD - metabolism | Animals | Respiratory Tract Infections - immunology | Female | Immunologic Memory | Mice | Receptor, Notch1 - genetics | Lung - immunology | Orthomyxoviridae Infections - immunology | Index Medicus
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2. Full Text Respiratory Syncytial Virus-Specific$CD8^+$Memory T Cell Responses in Elderly Persons
by Godelieve J. de Bree and Jojanneke Heidema and Ester M. M. van Leeuwen and Grada M. van Bleek and René E. Jonkers and Henk M. Jansen and René A. W. van Lier and Theo A. Out
The Journal of infectious diseases, ISSN 0022-1899, 5/2005, Volume 191, Issue 10, pp. 1710 - 1718
T lymphocytes | Human respiratory syncytial virus | Respiratory syncytial virus infections | Phenotypes | Memory | Respiratory syncytial viruses | Viruses | Cultured cells | Infections | Older adults | Receptors, Interleukin-7 - metabolism | Humans | Middle Aged | Receptors, CCR7 | Receptors, Chemokine - metabolism | Respiratory Syncytial Viruses - immunology | ADP-ribosyl Cyclase - metabolism | ADP-ribosyl Cyclase 1 | Antigens, CD - metabolism | CD28 Antigens - metabolism | Immunologic Memory - physiology | Aging - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Gene Expression - immunology | Adult | Aged | Membrane Glycoproteins | CD8-Positive T-Lymphocytes - immunology | Pulmonary Disease, Chronic Obstructive - immunology | HLA-DR Antigens - metabolism | Index Medicus | Abridged Index Medicus
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3. Full Text Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung
by de Bree, Godelieve J and van Leeuwen, Ester M. M and Out, Theo A and Jansen, Henk M and Jonkers, René E and van Lier, René A. W
The Journal of experimental medicine, ISSN 0022-1007, 2005, Volume 202, Issue 10, pp. 1433 - 1442
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | CD8-Positive T-Lymphocytes - cytology | Humans | Middle Aged | Respiratory Syncytial Viruses - immunology | Cells, Cultured | Lung - cytology | Cytokines - physiology | Orthomyxoviridae - immunology | CD4-Positive T-Lymphocytes - immunology | Lung - virology | Epitopes, T-Lymphocyte - physiology | Immunologic Memory | Aged | CD8-Positive T-Lymphocytes - immunology | Cell Aggregation - immunology | Lung - immunology | Index Medicus
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4. Full Text Protective effect of budesonide/formoterol compared with formoterol, salbutamol and placebo on repeated provocations with inhaled AMP in patients with asthma: a randomised, double-blind, cross-over study
by Aalbers, René and Boorsma, Martin and van der Woude, Hanneke J and Jonkers, René E
Respiratory research, ISSN 1465-9921, 2010, Volume 11, Issue 1, pp. 66 - 66
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Bronchodilator Agents - therapeutic use | Formoterol Fumarate | Glucocorticoids - administration & dosage | Glucocorticoids - therapeutic use | Bronchodilator Agents - administration & dosage | Humans | Middle Aged | Bronchial Provocation Tests | Male | Ethanolamines - administration & dosage | Forced Expiratory Volume | Young Adult | Bronchoconstrictor Agents - administration & dosage | Netherlands | Time Factors | Bronchoconstriction - drug effects | Adrenergic beta-Agonists - administration & dosage | Albuterol - administration & dosage | Adult | Female | Adrenergic beta-Agonists - therapeutic use | Asthma - physiopathology | Double-Blind Method | Administration, Inhalation | Treatment Outcome | Asthma - drug therapy | Cross-Over Studies | Adenosine Monophosphate - administration & dosage | Budesonide - therapeutic use | Albuterol - therapeutic use | Ethanolamines - therapeutic use | Budesonide - administration & dosage | Maximal Midexpiratory Flow Rate | Drug Combinations | Complications and side effects | Patient outcomes | Physiological aspects | Antiasthmatic agents | Dosage and administration | Research | Drug therapy, Combination | Adenylic acid | Drug therapy | Asthma | Prevention | Medical research | Usage | Care and treatment | Corticosteroids | Medicine, Experimental | Inflammation | Albuterol | Comparative analysis | Adenosine | Index Medicus
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5. Full Text CD8(+) T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung
by Piet, Berber and de Bree, Godelieve J and Smids-Dierdorp, Barbara S and van der Loos, Chris M and Remmerswaal, Ester B. M and von der Thüsen, Jan H and van Haarst, Jan M. W and Eerenberg, Jan P and ten Brinke, Anja and van der Bij, Wim and Timens, Wim and van Lier, René A. W and Jonkers, René E
The Journal of clinical investigation, ISSN 0021-9738, 2011, Volume 121, Issue 6, pp. 2254 - 2263
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | T-Lymphocyte Subsets - immunology | Up-Regulation | Pore Forming Cytotoxic Proteins - genetics | Pore Forming Cytotoxic Proteins - biosynthesis | Integrin alpha1beta1 - analysis | Humans | Middle Aged | Male | Granzymes - genetics | Blood Cells - immunology | Antigens, CD - analysis | Epithelium - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Influenza A virus - immunology | Granzymes - biosynthesis | Perforin | CD8-Positive T-Lymphocytes - chemistry | Gene Expression Regulation - immunology | Integrin alpha Chains - analysis | Immunophenotyping | NK Cell Lectin-Like Receptor Subfamily C - analysis | T-Lymphocyte Subsets - metabolism | Herpesviridae - immunology | T-Cell Antigen Receptor Specificity | Aged | CD8-Positive T-Lymphocytes - immunology | Lung - immunology | Cytotoxicity, Immunologic | Influenza, Human - immunology | Index Medicus | Abridged Index Medicus
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6. Full Text Characterization of CD4⁺ Memory T Cell Responses Directed against Common Respiratory Pathogens in Peripheral Blood and Lung
by Godelieve J. de Bree and Hans Daniels and Muriel van Schilfgaarde and Henk M. Jansen and Theo A. Out and René A. W. van Lier and René E. Jonkers
The Journal of infectious diseases, ISSN 0022-1899, 6/2007, Volume 195, Issue 11, pp. 1718 - 1725
T lymphocytes | Human respiratory syncytial virus | Antigens | Pathogens | Lungs | Memory | Viruses | Infections | Chronic obstructive pulmonary disease | Pathogenesis and Host Response | Blood | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Infectious diseases | Medical sciences | Microbiology | Lymphocyte Activation | Humans | Middle Aged | Influenza, Human - complications | CD4-Positive T-Lymphocytes - classification | Pulmonary Disease, Chronic Obstructive - complications | Haemophilus Infections - complications | Respiratory Syncytial Virus Infections - immunology | Orthomyxoviridae - immunology | CD4-Positive T-Lymphocytes - immunology | Respiratory Syncytial Virus, Human - immunology | Leukocytes, Mononuclear - immunology | Haemophilus Infections - microbiology | Haemophilus influenzae - immunology | Influenza, Human - virology | Aged | Haemophilus Infections - immunology | Pulmonary Disease, Chronic Obstructive - immunology | Respiratory Syncytial Virus Infections - virology | Immunologic Memory - immunology | Lung - immunology | Influenza, Human - immunology | Influenza viruses | Physiological aspects | Respiratory syncytial virus | Research | CD4 lymphocytes | Hemophilus influenzae | Index Medicus | Abridged Index Medicus
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7. Full Text Analysis of stem-cell-like properties of human CD161(++)IL-18R alpha(+) memory CD8(+) T cells
by Havenith, Simone H. C and Yong, Si La and Henson, Sian M and Piet, Berber and Idu, Mirza M and Koch, Sven D and Jonkers, René E and Kragten, Natasja A. M and Akbar, Arne N and van Lier, René A. W and ten Berge, Ineke J. M
International immunology, ISSN 0953-8178, 2012, Volume 24, Issue 10, pp. 625 - 636
Telomere erosion | CD161 | Memory stem cells | MAIT cells | Life Sciences & Biomedicine | Immunology | Science & Technology | CD8-Positive T-Lymphocytes - cytology | Stem Cells - immunology | Telomere - ultrastructure | Humans | NK Cell Lectin-Like Receptor Subfamily B - metabolism | Stem Cells - cytology | CD8-Positive T-Lymphocytes - ultrastructure | Stem Cells - metabolism | Telomere Homeostasis | Interleukin-18 Receptor alpha Subunit - metabolism | Stem Cells - ultrastructure | Microscopy, Electron, Scanning Transmission | CD8-Positive T-Lymphocytes - metabolism | Immunologic Memory | Telomerase - metabolism | CD8-Positive T-Lymphocytes - immunology | Index Medicus
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8. Full Text Onset of relief of dyspnoea with budesonide/formoterol or salbutamol following methacholine-induced severe bronchoconstriction in adults with asthma: a double-blind, placebo-controlled study
by Jonkers, René E and Bantje, Theo A and Aalbers, René
Respiratory research, ISSN 1465-9921, 2006, Volume 7, Issue 1, pp. 141 - 141
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Asthma - diagnosis | Formoterol Fumarate | Bronchodilator Agents - administration & dosage | Double-Blind Method | Dyspnea - diagnosis | Placebo Effect | Humans | Middle Aged | Bronchial Provocation Tests | Male | Treatment Outcome | Asthma - drug therapy | Ethanolamines - administration & dosage | Bronchoconstriction - drug effects | Adolescent | Albuterol - administration & dosage | Adult | Female | Bronchoconstrictor Agents | Budesonide - administration & dosage | Methacholine Chloride | Drug Combinations | Dyspnea - prevention & control | Usage | Care and treatment | Pitchers (Baseball) | Methacholine | Adults | Albuterol | Research | Comparative analysis | Asthma | Index Medicus
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9. Full Text Erratum: Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells
by Hombrink, Pleun and Helbig, Christina and Backer, Ronald A and Piet, Berber and Oja, Anna E and Stark, Regina and Brasser, Giso and Jongejan, Aldo and Jonkers, René E and Nota, Benjamin and Basak, Onur and Clevers, Hans C and Moerland, Perry D and Amsen, Derk and van Lier, René A W
Nature immunology, ISSN 1529-2908, 01/2017, Volume 18, Issue 2, pp. 246 - 246
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10. Full Text Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division
by Maia, Ana Rita R and Linder, Simon and Song, Ji-Ying and Vaarting, Chantal and Boon, Ute and Pritchard, Colin E. J and Velds, Arno and Huijbers, Ivo J and Van Tellingen, Olaf and Jonkers, Jos and Medema, René H
British journal of cancer, ISSN 0007-0920, 06/2018, Volume 118, Issue 12, pp. 1586 - 1595
Life Sciences & Biomedicine | Oncology | Science & Technology | Paclitaxel - pharmacology | Humans | Tumor Suppressor Protein p53 - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cell Cycle Proteins - antagonists & inhibitors | Docetaxel - administration & dosage | MCF-7 Cells | Neoplasms - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Cell Death - drug effects | BRCA1 Protein - deficiency | Paclitaxel - administration & dosage | Neoplasms - enzymology | Tumor Suppressor Protein p53 - deficiency | Cell Division - drug effects | Docetaxel - pharmacology | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Protein Kinase Inhibitors - administration & dosage | Animals | Mitosis - drug effects | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus | Cell division | Cancer therapy
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11. Full Text Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design
by van der Sluijs, Koenraad F and van de Pol, Marianne A and Kulik, Wim and Dijkhuis, Annemiek and Smids, Barbara S and van Eijk, Hetty W and Karlas, Jos A and Molenkamp, Richard and Wolthers, Katja C and Johnston, Sebastian L and van der Zee, Jaring S and Sterk, Peter J and Lutter, René and RESOLVE Res Team and RESOLVE research team and the RESOLVE research team
Thorax, ISSN 0040-6376, 12/2013, Volume 68, Issue 12, pp. 1122 - 1130
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Prospective Studies | Cytokines - analysis | Humans | Quinolinic Acid - blood | Male | Nitric Oxide - analysis | Case-Control Studies | Picornaviridae Infections - virology | Young Adult | ortho-Aminobenzoates - analysis | Kynurenine - blood | Tryptophan - blood | Kynurenine - analysis | Peroxidase - analysis | Adult | Female | Bronchoalveolar Lavage Fluid - cytology | Rhinovirus | Eosinophil Cationic Protein - analysis | ortho-Aminobenzoates - blood | Asthma - physiopathology | Asthma - enzymology | Biomarkers - analysis | Breath Tests | Biomarkers - blood | Disease Progression | Asthma - complications | Quinolinic Acid - analysis | Bronchoalveolar Lavage Fluid - chemistry | Picornaviridae Infections - complications | Eosinophils | Tryptophan - analysis | Prognosis | Rhinoviruses | Tryptophan | Influence | Research | Risk factors | Asthma | Index Medicus
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12. Full Text Disease variants alter transcription factor levels and methylation of their binding sites
by Bonder, Marc Jan and Luijk, Rene and Pital-Zhernakova, Daria and Moed, Matthijs and Deelen, Patrick and Vermaat, Martijn and van Iterson, Maarten and van Dijk, Freerk and van Galen, Michiel and Bot, Jan and Slieker, Roderick C and Jhamai, P. Mila and Verbiest, Michael and Suchiman, H. Eka D and Verkerk, Marijn and van der Breggen, Ruud and van Rooij, Jeroen and Lakenberg, Nico and Arinarto, Wibowo and Kielbasa, Szymon M and Jonkers, Iris and van 't Hof, Peter and Nooren, Irene and Beekman, Marian and Deelen, Joris and van Heemst, Diana and Zhernakova, Alexana and Tigchelaar, Ettje F and Swertz, Morris A and Hofman, Albert and Uitterlinden, Ane G and Pool, Rene and van Dongen, Jenny and Hottenga, Jouke J and Stehouwer, Coen D. A and van der Kallen, Carla J. H and Schalkwijk, Casper G and van den Berg, Leonard H and van Zwet, Erik W and Mei, Hailiang and Li, Yang and Lemire, Mathieu and Hudson, Thomas J and Slagboom, P. Eline and Wijmenga, Cisca and Veldink, Jan H and van Greevenbroek, Marleen M. J and van Duijn, Cornelia M and Boomsma, Dorret I and Franke, Lude and BIOS Consortium and the BIOS Consortium
Nature genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, pp. 131 - 138
DNA | GENE-EXPRESSION | SUSCEPTIBILITY LOCI | ARCHITECTURE | PROTEINS | GENOME-WIDE ASSOCIATION | FAMILY | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genome-Wide Association Study | Disease - genetics | Humans | Middle Aged | Gene Expression Regulation | Male | Transcription Factors - metabolism | DNA Methylation | Phenotype | Polymorphism, Single Nucleotide - genetics | Female | Genome, Human | Quantitative Trait Loci | Binding Sites | Cohort Studies | Transcription factors | Methylation | Analysis | Binding sites (Biochemistry) | Studies | Consortia | DNA methylation | Genetic research | Infrastructure | Genomes | Gene expression | Blood | Deoxyribonucleic acid--DNA | Index Medicus
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