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The New England Journal of Medicine, ISSN 0028-4793, 01/2013, Volume 368, Issue 2, pp. 107 - 116
Journal Article
Nature Genetics, ISSN 1061-4036, 2009, Volume 41, Issue 1, pp. 18 - 24
Journal Article
Journal Article
by Gudbjartsson, Daniel F and Bjornsdottir, Unnur S and Halapi, Eva and Helgadottir, Anna and Sulem, Patrick and Jonsdottir, Guun M and Thorleifsson, Gudmar and Helgadottir, Hafdis and Steinthorsdottir, Valgerdur and Stefansson, Hreinn and Williams, Carolyn and Hui, Jennie and Beilby, John and Warrington, Nicole M and James, Alan and Palmer, Lyle J and Koppelman, Gerard H and Heinzmann, Anea and Krueger, Marcus and Boezen, H. Marike and Wheatley, Amanda and Altmuller, Janine and Shin, Hyoung Doo and Uh, Soo-Taek and Cheong, Hyun Sub and Jonsdottir, Brynja and Gislason, David and Park, Choon-Sik and Rasmussen, Linda M and Porsbjerg, Celeste and Hansen, Jakob W and Backer, Vibeke and Werge, Thomas and Janson, Christer and Joensson, Ulla-Britt and Ng, Maggie C. Y and Chan, Juliana and So, Wing Yee and Ma, Ronald and Shah, Svati H and Granger, Christopher B and Quyyumi, Arshed A and Levey, Allan I and Vaccarino, Viola and Reilly, Muredach P and Rader, Daniel J and Williams, Michael J. A and van Rij, Ane M and Jones, Gregory T and Trabetti, Elisabetta and Malerba, Giovanni and Pignatti, Pier Franco and Boner, Attilio and Pescollderungg, Lydia and Girelli, Domenico and Olivieri, Oliviero and Martinelli, Nicola and Ludviksson, Bjorn R and Ludviksdottir, Dora and Eyjolfsson, Gudmundur I and Arnar, David and Thorgeirsson, Gudmundur and Deichmann, Klaus and Thompson, Philip J and Wjst, Matthias and Hall, Ian P and Postma, Dirkje S and Gislason, Thorarinn and Gulcher, Jeffrey and Kong, Augustine and Jonsdottir, Ingileif and Thorsteinsdottir, Unnur and Stefansson, Kari and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Lungmedicin och allergologi and Uppsala universitet and Institutionen för medicinska vetenskaper
Nature Genetics, ISSN 1061-4036, 03/2009, Volume 41, Issue 3, pp. 342 - 347
Journal Article
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 11, pp. 1584 - 1592
Persistent insomnia is among the most frequent complaints in general practice. To identify genetic factors for insomnia complaints, we performed a genome-wide... 
SLEEP DISTURBANCE | HUMAN HEIGHT | POPULATION | METAANALYSIS | RESTLESS LEGS SYNDROME | MYOCARDIAL-INFARCTION | VARIANTS | GENETICS & HEREDITY | SEX-DIFFERENCES | PERSISTENT INSOMNIA | EPIDEMIOLOGY | Humans | Type D Personality | Male | Educational Status | Genetic Loci | Gene Regulatory Networks | Restless Legs Syndrome - genetics | Restless Legs Syndrome - metabolism | Adult | Female | Quality of Life - psychology | Neoplasm Proteins - genetics | Sleep Initiation and Maintenance Disorders - metabolism | Gene Expression | Genetic Predisposition to Disease | Genome-Wide Association Study | Restless Legs Syndrome - physiopathology | Gene Frequency | Chromosome Mapping | Homeodomain Proteins - genetics | Protein Interaction Mapping | Restless Legs Syndrome - psychology | Alleles | Sex Factors | Sleep Initiation and Maintenance Disorders - genetics | Sleep Initiation and Maintenance Disorders - physiopathology | Polymorphism, Single Nucleotide | Myeloid Ecotropic Viral Integration Site 1 Protein | Genome, Human | Sleep Initiation and Maintenance Disorders - psychology | Care and treatment | Genome-wide association studies | Insomnia | Development and progression | Genotype | Genetic aspects | Health aspects | Methods | Legs | Psychological factors | Genes | Association analysis | Gender differences | Genomes | Metabolism | Loci | Independent sample | Studies | Restless legs syndrome | Sleep disorders | Pleiotropy | Sexes | Genetic factors | Bioinformatics | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2008, Volume 105, Issue 4, pp. 1303 - 1308
Journal Article
Nature communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, pp. 599 - 599
Human IgG3 displays the strongest effector functions of all IgG subclasses but has a short half-life for unresolved reasons. Here we show that IgG3 binds to... 
COMPLEX | CHIMERIC ANTIBODIES | GAMMA RECEPTORS | SUBCLASSES | AFFINITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | I-RELATED RECEPTOR | BINDING DOMAIN | IMMUNOGLOBULIN-G | ANTIGEN | Pneumococcal Infections - drug therapy | Agammaglobulinemia - immunology | Pneumococcal Infections - metabolism | Arginine - immunology | Humans | Receptors, Fc - metabolism | Half-Life | Antibodies, Monoclonal - therapeutic use | Histidine - metabolism | Agammaglobulinemia - metabolism | Streptococcus pneumoniae - immunology | Histocompatibility Antigens Class I - metabolism | Protein Transport - immunology | Agammaglobulinemia - pathology | Pneumococcal Infections - immunology | Agammaglobulinemia - drug therapy | Immunoglobulin G - immunology | Arginine - genetics | Antibodies, Monoclonal - immunology | Molecular Targeted Therapy - methods | Disease Models, Animal | Binding, Competitive | Streptococcus pneumoniae - drug effects | Histocompatibility Antigens Class I - immunology | Histidine - genetics | Immunoglobulin G - therapeutic use | Histidine - immunology | Immunoglobulin G - administration & dosage | Animals | Receptors, Fc - immunology | Antibodies, Monoclonal - administration & dosage | Cell Line, Tumor | Protein Binding | Mice | Antibodies, Monoclonal - metabolism | Arginine - metabolism | Amino Acid Substitution | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism | Index Medicus
Journal Article
by Bonnelykke, Klaus and Matheson, Melanie C and Pers, Tune H and Granell, Raquel and Strachan, David P and Alves, Alexessander Couto and Linneberg, Allan and Curtin, John A and Warrington, Nicole M and Standl, Marie and Kerkhof, Marjan and Jonsdottir, Ingileif and Bukvic, Blazenka K and Kaakinen, Marika and Sleimann, Patrick and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Schramm, Katharina and Baltic, Svetlana and Kreiner-Moller, Eskil and Simpson, Angela and St Pourcain, Beate and Coin, Lachlan and Hui, Jennie and Walters, Eugene H and Tiesler, Carla M. T and Duffy, David L and Jones, Graham and Ring, Susan M and McArdle, Wendy L and Price, Loren and Robertson, Colin F and Pekkanen, Juha and Tang, Clara S and Thiering, Elisabeth and Montgomery, Grant W and Hartikainen, Anna-Liisa and Dharmage, Shyamali C and Husemoen, Lise L and Herder, Christian and Kemp, John P and Elliot, Paul and James, Alan and Waldenberger, Melanie and Abramson, Michael J and Fairfax, Benjamin P and Knight, Julian C and Gupta, Ramneek and Thompson, Philip J and Holt, Patrick and Sly, Peter and Hirschhorn, Joel N and Blekic, Mario and Weidinger, Stephan and Hakonarsson, Hakon and Stefansson, Kari and Heinrich, Joachim and Postma, Dirkje S and Custovic, Adnan and Pennell, Craig E and Jarvelin, Marjo-Riitta and Koppelman, Gerard H and Timpson, Nicholas and Ferreira, Manuel A and Bisgaard, Hans and Henderson, A. John and AAGC and EAGLE Consortium and the EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortium and Australian Asthma Genetics Consortium (AAGC)
Nature Genetics, ISSN 1061-4036, 08/2013, Volume 45, Issue 8, pp. 902 - 906
Journal Article
Journal Article
by Wain, Louise V and Shrine, Nick R. G and Artigas, Maria Soler and Erzurumluoglu, A Mesut and Noyvert, Boris and Bossini-Castillo, Lara and Obeidat, Ma'en and Henrys, Amanda P and Portelli, Michael A and Hall, Robert J and Billington, Charlotte K and Rimington, Tracy L and Fenech, Anthony G and John, Catherine and Blake, Tineka and Jackson, Victoria E and Allen, Richard J and Prins, Bram P and Campbell, Archie and Porteous, David J and Jarvelin, Marjo-Riitta and Wielscher, Matthias and Jamess, Alan L and Hui, Jennie and Wareham, Nicholas J and Zhao, Jing Hua and Wilson, James F and Joshi, Peter K and Stubbe, Beate and Rawal, Rajesh and Schulz, Holger and Imboden, Medea and Probst-Hensch, Nicole M and Karrasch, Stefan and Gieger, Christian and Deary, Ian J and Harris, Sarah E and Marten, Jonathan and Rudan, Igor and Enroth, Stefan and Gyllensten, Ulf and Kerr, Shona M and Polasek, Ozren and Kahonen, Mika and Surakka, Ida and Vitart, Veronique and Hayward, Caroline and Lehtimaki, Terho and Raitakari, Olli T and Evans, David M and Henderson, A. John and Pennell, Craig E and Wang, Carol A and Sly, Peter D and Wan, Emily S and Busch, Robert and Hobbs, Brian D and Litonjua, Augusto and Sparrow, David W and Gulsvik, Amund and Bakke, Per S and Crapo, James D and Beaty, Terri H and Hansel, Nadia N and Mathias, Rasika A and Ruczinski, Ingo and Barnes, Kathleen C and Bosse, Yohan and Joubert, Philippe and van den Berge, Maarten and Brandsma, Corry-Anke and Pare, Peter D and Sin, Don and Nickle, David C and Hao, Ke and Gottesman, Omri and Dewey, Frederick E and Bruse, Shannon E and Carey, David J and Kirchner, H Lester and Jonsson, Stefan and Thorleifsson, Gudmar and Jonsdottir, Ingileif and Gislason, Thorarinn and Stefansson, Kari and Schurmann, Claudia and Nadkarni, Girish N and Bottinger, Erwin P and Loos, Ruth J. F and Walters, Robin G and Chen, Zhengming and Millwood, Iona Y and Vaucher, Julien and Kurmi, Om P and Li, Liming and Hansell, Anna L and Brightling, Chris and Zeggini, Eleftheria and Cho, Michael H and Silverman, Edwin K and ... and Geisinger-Regeneron DiscovEHR and Understanding Soc Sci Grp and Understanding Society Scientific Group and Geisinger-Regeneron DiscovEHR Collaboration and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 03/2017, Volume 49, Issue 3, pp. 416 - 425
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide... 
VARIANTS | GENETICS | SUSCEPTIBILITY | FAM13A | GENETICS & HEREDITY | RISK | EPIDEMIOLOGY | HISTORY | Genetic Predisposition to Disease - genetics | Humans | Middle Aged | Risk Factors | Genetic Loci - genetics | Male | Lung - physiopathology | Asthma - genetics | Epigenesis, Genetic - genetics | Alleles | Aged, 80 and over |