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Angewandte Chemie International Edition, ISSN 1433-7851, 02/2019, Volume 58, Issue 9, pp. 2734 - 2738
The hypercalins are dearomatized acylphloroglucinols with a pendant complex cyclopentane ring that exhibit activity against several cancer cell lines. We... 
Suzuki–Miyaura coupling | β-lactone | C−H insertion | chiral pool | protonophore | Biological effects | Synthesis | Congeners | Cell lines | Antitumor activity | Cyclopentane | Tumor cell lines | Cancer | Anticancer properties
Journal Article
Angewandte Chemie, ISSN 0044-8249, 02/2019, Volume 131, Issue 9, pp. 2760 - 2764
The hypercalins are dearomatized acylphloroglucinols with a pendant complex cyclopentane ring that exhibit activity against several cancer cell lines. We... 
Protonophore | Suzuki-Miyaura-Kupplung | Chiraler Pool | β-Lacton | C-H-Insertion | Care and treatment | Synthesis | Organic compounds | Cancer | Biological effects | Congeners | Cell lines | Antitumor activity | Cyclopentane | Tumor cell lines | Anticancer properties
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 35, pp. 15449 - 15454
Journal Article
Oncogene, ISSN 0950-9232, 06/2015, Volume 34, Issue 23, pp. 2958 - 2967
Journal Article
Oncogene, ISSN 0950-9232, 11/2016, Volume 35, Issue 46, pp. 5963 - 5976
Advanced prostate adenocarcinomas enriched in stem-cell features, as well as variant androgen receptor (AR)-negative neuroendocrine (NE)/small-cell prostate... 
ANDROGEN RECEPTOR | ACTIVATION | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROENDOCRINE DIFFERENTIATION | KINASE INHIBITORS | CELL BIOLOGY | BREAST-CANCER | TO-MESENCHYMAL TRANSITION | P38 | ONCOLOGY | GENETICS & HEREDITY | RESISTANCE | AGGRESSIVE PHENOTYPE | Prostatic Neoplasms - metabolism | Recurrence | Neoplastic Stem Cells - drug effects | Humans | Receptors, Androgen - metabolism | Drug Resistance, Neoplasm | Male | Epithelial-Mesenchymal Transition - genetics | Zinc Finger E-box-Binding Homeobox 1 - metabolism | Neoplasm Grading | Neoplastic Stem Cells - metabolism | Forkhead Transcription Factors - metabolism | Prostate-Specific Antigen - metabolism | Prostatic Neoplasms - drug therapy | Disease Models, Animal | Phenylthiohydantoin - pharmacology | Prostatic Neoplasms - pathology | Epithelium - pathology | Gene Expression | Epithelium - metabolism | Forkhead Transcription Factors - genetics | Phenylthiohydantoin - analogs & derivatives | Xenograft Model Antitumor Assays | Phenotype | Animals | MAP Kinase Signaling System - drug effects | Models, Biological | Cell Line, Tumor | Mice | Androgens - metabolism | Physiological aspects | Development and progression | Genetic aspects | Research | Prostate cancer | Cancer cells | Cell growth | Transcription factors | Cancer therapies | Stem cells | Index Medicus | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64169
Journal Article
Scientific reports, ISSN 2045-2322, 2013, Volume 3, Issue 1, p. 2687
Journal Article
Breast Cancer Research, ISSN 1465-5411, 03/2019, Volume 21, Issue 1, pp. 37 - 14
Triple-negative breast cancers (TNBCs), which lack receptors for estrogen, progesterone, and amplification of epidermal growth factor receptor 2, are highly... 
Epithelial-mesenchymal transition (EMT) | Wnt signaling | Cancer stem cells (CSCs) | Triple-negative breast cancer (TNBC) | Glycogen synthase kinase β (GSK3β)
Journal Article