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glutaraldehyde (4) 4
humans (4) 4
oncology (4) 4
alpha-amylase (3) 3
animals (3) 3
antineoplastic agents - pharmacology (3) 3
carrier-free coimmobilization (3) 3
cell proliferation - drug effects (3) 3
chemistry, multidisciplinary (3) 3
enzymes (3) 3
growth (3) 3
imidazoles - pharmacology (3) 3
immobilization (3) 3
index medicus (3) 3
mice (3) 3
activin receptors, type ii - antagonists & inhibitors (2) 2
administration, oral (2) 2
anticancer (2) 2
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cancer (2) 2
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cell line, tumor (2) 2
chemistry, medicinal (2) 2
combi-cleas (2) 2
cross-linked enzyme aggregates (2) 2
dose-response relationship, drug (2) 2
enterolactone (2) 2
enzyme immobilization (2) 2
features (2) 2
glucoamylase (2) 2
lipase (2) 2
male (2) 2
metastasis (2) 2
polyethyleneimine (2) 2
quinolines - pharmacology (2) 2
secondary structure (2) 2
silver nanoparticles (2) 2
stat3 (2) 2
tor serine-threonine kinases - antagonists & inhibitors (2) 2
acrylic copolymer (1) 1
activation (1) 1
aged (1) 1
aggregates (1) 1
aggregates combi-cleas (1) 1
alpha amylase (1) 1
ammonium compounds (1) 1
ammonium paratungstate (1) 1
amylases (1) 1
analysis (1) 1
angiogenesis inhibitors - administration & dosage (1) 1
angiogenesis inhibitors - pharmacology (1) 1
anti-inflammatory agents - pharmacology (1) 1
antiinflammatory (1) 1
antineoplastic agents - chemistry (1) 1
antioxidants (1) 1
antitumor-activity (1) 1
aorta, thoracic - cytology (1) 1
aorta, thoracic - drug effects (1) 1
apoptosis (1) 1
apoptosis - drug effects (1) 1
articular chondrocytes (1) 1
asian americans (1) 1
beta-lactam antibiotics (1) 1
biocatalytic synthesis (1) 1
biochemistry & molecular biology (1) 1
biological evaluation (1) 1
biosynthesis of metal nanoparticles (1) 1
bovine serum-albumin (1) 1
breast cancer (1) 1
breast cancer metastasis (1) 1
cancer research (1) 1
candida-rugosa lipase (1) 1
carcinoma, non-small-cell lung - drug therapy (1) 1
carcinoma, non-small-cell lung - metabolism (1) 1
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cartilage explants (1) 1
cell-proliferation (1) 1
challenges (1) 1
chemistry, physical (1) 1
chemotherapy (1) 1
chondroprotective (1) 1
class i phosphatidylinositol 3-kinases (1) 1
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crosslinking (1) 1
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drug resistance, neoplasm - drug effects (1) 1
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1. Full Text Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial-mesenchymal transition
by Mali, Aniket V and Joshi, Asavari A and Hegde, Mahabaleshwar V and Kadam, Shivajirao S
Cancer Biology and Medicine, ISSN 2095-3941, 05/2018, Volume 15, Issue 2, pp. 137 - 156
Objective: Triple negative breast cancer (TNBC) is highly metastatic, and there is an urgent unmet need to develop novel therapeutic strategies leading to the... 
Breast cancer metastasis | Enterolactone | EMT | Migration | Invasion | MEDICINE, RESEARCH & EXPERIMENTAL | METASTASIS | breast cancer metastasis | TRANSCRIPTION | DOWN-REGULATION | CHALLENGES | INVASIVENESS | invasion | ONCOLOGY | GROWTH | migration | LIGNANS | EXPRESSION | SNAIL | Original
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2. Full Text Parameters in preparation and characterization of cross linked enzyme aggregates (CLEAs)
by Talekar, Sachin and Joshi, Asavari and Joshi, Gandhali and Kamat, Priyanka and Haripurkar, Rutumbara and Kambale, Shashikant
RSC Advances, ISSN 2046-2069, 08/2013, Volume 3, Issue 31, pp. 12485 - 12511
In the past couple of decades, cross linked enzyme aggregates (CLEAs) have emerged as a novel and versatile carrier free immobilization technique. The... 
PENICILLIN-G ACYLASE | ENANTIOSELECTIVE NITRILE HYDROLYSIS | ORGANIC-SOLVENTS | CANDIDA-RUGOSA LIPASE | OPTIMUM PERFORMANCE | BETA-LACTAM ANTIBIOTICS | IMMOBILIZED ENZYMES | CHEMISTRY, MULTIDISCIPLINARY | BOVINE SERUM-ALBUMIN | OF-THE-ART | BIOCATALYTIC SYNTHESIS
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3. Pectin cross-linked enzyme aggregates (pectin-CLEAs) of glucoamylase
by Talekar, Sachin and Nadar, Shamraja and Joshi, Asavari and Joshi, Gandhali
RSC Advances, 11/2014, Volume 4, Issue 103, pp. 59444 - 59453
Pectin cross-linked enzyme aggregates (pectin-CLEAs) of glucoamylase were prepared for the first time with pectin as cross-linking agent. Pectin as a... 
Enzymes | Aggregates | Crosslinking | Formations | Glucoamylase | Pectin | Recovery
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4. Full Text A tri-enzyme magnetic nanobiocatalyst with one pot starch hydrolytic activity
by Talekar, Sachin and Joshi, Asavari and Kambale, Shashikant and Jadhav, Suraj and Nadar, Shamraja and Ladole, Mayur
Chemical Engineering Journal, ISSN 1385-8947, 10/2017, Volume 325, pp. 80 - 90
An efficient tri-enzyme magnetic nanobiocatalyst for one pot starch hydrolysis was constructed by co-immobilization of commercially available alpha amylase,... 
Co-immobilization | Glucoamylase | Alpha amylase | Magnetic nanoparticles | Starch hydrolysis | Pullulanase | COVALENT ATTACHMENT | FE3O4 NANOPARTICLES | CARRIER-FREE COIMMOBILIZATION | AGGREGATES COMBI-CLEAS | ENGINEERING, CHEMICAL | FACILE SYNTHESIS | ENGINEERING, ENVIRONMENTAL | ACRYLIC COPOLYMER | IMMOBILIZED BETA-AMYLASE | ALPHA-AMYLASE | Enzymes | Hydrolysis | Ferric oxide | Amylases
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5. Full Text Pectin cross-linked enzyme aggregates (pectin-CLEAs) of glucoamylase
by Talekar, Sachin and Nadar, Shamraja and Joshi, Asavari and Joshi, Gandhali
RSC Advances, ISSN 2046-2069, 2014, Volume 4, Issue 103, pp. 59444 - 59453
Pectin cross-linked enzyme aggregates (pectin-CLEAs) of glucoamylase were prepared for the first time with pectin as cross-linking agent. Pectin as a... 
CANDIDA-RUGOSA | COMBI-CLEAS | CARRIER-FREE COIMMOBILIZATION | SECONDARY STRUCTURE | LIPASE | POLYETHYLENEIMINE | GLUTARALDEHYDE | CHEMISTRY, MULTIDISCIPLINARY | IMMOBILIZATION | ALPHA-AMYLASE | FEATURES
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6. Immobilized enzyme mediated synthesis of silver nanoparticles using cross-linked enzyme aggregates (CLEAs) of NADH-dependent nitrate reductase
by Talekar, Sachin and Joshi, Asavari and Chougle, Radhika and Nakhe, Arya and Bhojwani, Rahul
Nano-Structures and Nano-Objects, 04/2016, Volume 6, pp. 23 - 33
NADH-dependent nitrate reductase CLEAs catalyzed synthesis of silver nanoparticles from silver nitrate has been investigated. NADH-dependent nitrate reductase... 
Cross-linked enzyme aggregates (CLEAs) | Enzyme immobilization | Nitrate reductase | Silver nanoparticles
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7. Full Text Enterolactone Suppresses Proliferation, Migration and Metastasis of MDA-MB-231 Breast Cancer Cells Through Inhibition of uPA Induced Plasmin Activation and MMPs-Mediated ECM Remodeling
by Mali, Aniket V and Joshi, Asavari A and Hegde, Mahabaleshwar V and Kadam, Shivajirao S
Asian Pacific journal of cancer prevention : APJCP, ISSN 1513-7368, 04/2017, Volume 18, Issue 4, pp. 905 - 915
Background: To enhance their own survival, tumor cells can manipulate their microenvironment through remodeling of the extra cellular matrix (ECM). The... 
breast cancer | Urokinase-type plasminogen activator | Enterolactone | matrix metalloproteinases
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8. Full Text P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer
by Venkatesha, Venkatasubbaiah A and Joshi, Asavari and Venkataraman, Magesh and Sonawane, Vinay and Bhatia, Dimple and Tannu, Prashant and Bose, Julie and Choudhari, Sarika and Srivastava, Ankita and Pandey, Kumar and Lad, Vaibhavi J and Sangana, Ramachandra and Ahmed, Tausif and Damre, Anagha and Deore, Vijaykumar and Sahu, Bichismita and Kumar, Sanjay and Sharma, Somesh and Agarwal, Veena R
Molecular Cancer, ISSN 1476-4598, 12/2014, Volume 13, Issue 1, p. 259
Background: Lung cancer is the major cause of cancer-related deaths and many cases of Non Small Cell Lung Cancer (NSCLC), a common type of lung cancer, have... 
Tumor xenograft | NSCLC | PI3K | STAT3 | Targeted therapeutics | EGFR-TKI | mTORC2 | PK-PD | mTORC1 | GEFITINIB | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTITUMOR-ACTIVITY | EGFR | CHEMOTHERAPY | KRAS MUTATIONS | STAT3 ACTIVATION | K-RAS | ONCOLOGY | RESISTANCE | TUMOR-GROWTH | Erlotinib Hydrochloride | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins p21(ras) | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Activin Receptors, Type II - antagonists & inhibitors | Male | Mechanistic Target of Rapamycin Complex 2 | Quinolines - pharmacology | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | ras Proteins - pharmacology | Phosphatidylinositol 3-Kinases - pharmacology | Antineoplastic Agents - pharmacology | Receptor, Epidermal Growth Factor - pharmacology | Phosphorylation - drug effects | Proto-Oncogene Proteins - pharmacology | Carcinoma, Non-Small-Cell Lung - metabolism | Imidazoles - pharmacology | Animals | Class I Phosphatidylinositol 3-Kinases | Mice, Nude | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | HeLa Cells | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Medical equipment and supplies industry | Growth | Health aspects | Medical test kit industry | Mutation | Kinases | Lung cancer | Rodents
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9. Full Text Abstract 4521: P7170, a novel inhibitor of phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) and activin receptor-like kinase 1 (ALK1) shows anti-tumor activity in triple negative breast cancer
by Agarwal, Veena R and Bhatia, Dimple and Joshi, Asavari and Mishra, Prabha and Bharadwaj, Kalyani G and lobo, Aurelio S and Menon, Pranoy and Dhar, Payal and Pandey, Prashant and Srinivasa, Sreesha and sonawane, vinay
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 4521 - 4521
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10. Full Text Preparation of stable cross-linked enzyme aggregates (CLEAs) of NADH-dependent nitrate reductase and its use for silver nanoparticle synthesis from silver nitrate
by Talekar, Sachin and Joshi, Gandhali and Joshi, Asavari and Chougle, Radhika and Nainegali, Basavaraj and Desai, Shashikant and Kambale, Shashikant and Kamat, Priyanka and Haripurkar, Rutumbara and Jadhav, Suraj and Nadar, Shamraja
Catalysis Communications, ISSN 1566-7367, 08/2014, Volume 53, pp. 62 - 66
The NADH-dependent nitrate reductase from cell extract was directly immobilized as cross linked enzyme aggregates (CLEAs) and investigated for the synthesis of... 
NADH-dependent nitrate reductase | Enzyme immobilization | Enzyme catalysis | Biosynthesis of metal nanoparticles | Cross-linked enzyme aggregates | Silver nanoparticles | IMPROVE | PERFORMANCE | STABILITY | CHEMISTRY, PHYSICAL | GLUTARALDEHYDE | IMMOBILIZATION | OPTIMIZATION | Ammonium compounds | Enzymes | Usage | Crosslinked polymers | Ammonium paratungstate | Analysis | Silver nitrate | Sulfates
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11. Discovery of P3971 an orally efficacious novel anticancer agent targeting HIF-1α and STAT3 pathways
by Godse, Pallavi and Kumar, Pramod and Yewalkar, Nilambari and Deore, Vijaykumar and Lohar, Manoj and Mundada, Ramswaroop and Padgaonkar, Amol and Manohar, Sonal and Joshi, Asavari and Bhatia, Dimple and Desai, Nikesh and Damre, Anagha and Bhonde, Mandar and Joshi, Kalpana and Sharma, Rajiv and Kumar, Sanjay
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 2013, Volume 13, Issue 9, pp. 1460 - 1466
Hypoxia-inducible factor-1 alpha (HIF-1 alpha) and signal transducer and activator of transcription 3 (STAT3) are transcription factors and are activated in... 
Imidazopyridine | HIF-1α | Drug discovery | Anticancer | STAT3 | CHEMISTRY, MEDICINAL | HIF-1 alpha | PI3-KINASE P110-ALPHA INHIBITORS | imidazopyridine | HYPOXIA | CANCER | HIF-1 | THERAPY | drug discovery | ONCOLOGY | BIOLOGICAL EVALUATION | DERIVATIVES | Neoplasms - metabolism | Humans | Imidazoles - chemistry | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Structure-Activity Relationship | Antineoplastic Agents - administration & dosage | Dose-Response Relationship, Drug | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Antineoplastic Agents - pharmacology | Molecular Structure | Imidazoles - chemical synthesis | Tumor Cells, Cultured | STAT3 Transcription Factor - metabolism | Sulfonamides - chemistry | Administration, Oral | Imidazoles - pharmacology | Antineoplastic Agents - chemistry | Mice, SCID | Sulfonamides - pharmacology | Drug Discovery | Neoplasms - drug therapy | Sulfonamides - chemical synthesis | Animals | Cell Proliferation - drug effects | Mice | Neoplasms - pathology | STAT3 Transcription Factor - antagonists & inhibitors | Drug Screening Assays, Antitumor
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12. Full Text Abstract 3759: P7170, a novel inhibitor of phosphoinositide 3-kinase (PI3K)-mammalian target of Rapamycin (mTOR) and activin receptor-like kinase 1 (ALK1) as a new therapeutic option for Kras mutated non small cell lung cancer (NSCLC)
by Agarwal, Veena R and Joshi, Asavari and Venkataraman, Magesh and Bhatia, Dimple and Bose, Julie and Kolla, Lakshmi Sireesha and Gill, Parkash and Sharma, Somesh
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 3759 - 3759
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13. Full Text Abstract 3437: P276, a cyclin-dependent kinase inhibitor with antitumor activity against high-risk human cervical cancer
by Shangary, Sanjeev Kumar and Deshpande, Gandhali and Sonawane, Vinay and Venkatasubbaiah, Venkatesha and Jalota-Badhwar, Archana and Joshi, Asavari and Mayekar, Manoj and Shirsath, Nitesh and Pandey, Prashant and Agarwal, Veena R
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 3437 - 3437
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14. Full Text Pectin cross-linked enzyme aggregates (pectin-CLEAs) of glucoamylaseElectronic supplementary information (ESI) available: Original and second derivative FTIR spectra of free enzyme and pectin-CLEAs. See DOI: 10.1039/c4ra09552a
by Talekar, Sachin and Nadar, Shamraja and Joshi, Asavari and Joshi, Gandhali
11/2014, Volume 4, Issue 13, pp. 59444 - 59453
Pectin cross-linked enzyme aggregates (pectin-CLEAs) of glucoamylase were prepared for the first time with pectin as cross-linking agent. Pectin as a... 
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15. DBCrypto: A Database Encryption System using Query Level Approach
by Asavari Deshpande and Anup Patil and Saurabh Joshi and Suraj Bothara
International Journal of Computer Applications, ISSN 0975-8887, 01/2012, Volume 45, Issue 8
  Online applications are vulnerable to theft of sensitive information because adversaries can exploit software bugs to gain access to private data and because... 
Databases | Query processing | Data base management systems | On-line systems | Tables | Encryption | Gain | Leaks
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16. Full Text P7170: A Novel Molecule with Unique Profile of mTORC1/C2 and Activin Receptor-like Kinase 1 Inhibition Leading to Antitumor and Antiangiogenic Activity
by Jalota-Badhwar, Archana and Jalota-Badhwar, Archana and Bhatia, Dimple R and Bhatia, Dimple R and Boreddy, Srinivas and Boreddy, Srinivas and Joshi, Asavari and Joshi, Asavari and Venkatraman, Magesh and Venkatraman, Magesh and Desai, Nikesh and Desai, Nikesh and Chaudhari, Sarika and Chaudhari, Sarika and Bose, Julie and Bose, Julie and Kolla, Lakshmi S and Kolla, Lakshmi S and Deore, Vijaykumar and Deore, Vijaykumar and Yewalkar, Nilambari and Yewalkar, Nilambari and Kumar, Sanjay and Kumar, Sanjay and Sharma, Rajiv and Sharma, Rajiv and Damre, Anagha and Damre, Anagha and More, Avinash and More, Avinash and Sharma, Somesh and Sharma, Somesh and Agarwal, Veena R and Agarwal, Veena R
Molecular cancer therapeutics, ISSN 1535-7163, 2015, Volume 14, Issue 5, pp. 1095 - 1106
The mTOR pathway is often upregulated in cancer and thus intensively pursued as a target to design novel anticancer therapies. Approved and emerging drugs... 
TARGET | RAPAMYCIN | ACTIVATION | ONCOLOGY | PATHWAY | GROWTH | NVP-BEZ235 | MONOCLONAL-ANTIBODY | CELL-PROLIFERATION | GENERATION | CANCER | Human Umbilical Vein Endothelial Cells | Prostatic Neoplasms - metabolism | Humans | Activin Receptors, Type II - antagonists & inhibitors | Imidazoles - administration & dosage | Male | Antineoplastic Agents - administration & dosage | Quinolines - administration & dosage | Quinolines - pharmacology | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Angiogenesis Inhibitors - administration & dosage | Antineoplastic Agents - pharmacology | Aorta, Thoracic - drug effects | Prostatic Neoplasms - drug therapy | Administration, Oral | Angiogenesis Inhibitors - pharmacology | Rats | Imidazoles - pharmacology | Hep G2 Cells | Xenograft Model Antitumor Assays | Aorta, Thoracic - cytology | Animals | Cell Line, Tumor | Cell Proliferation - drug effects | Mice
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17. Full Text Abstract 3742: P7170: A potent and oral phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) and activin receptor-like kinase 1 (ALK1) inhibitor with anti-tumor and anti-angiogenic activity
by Agarwal, Veena R and Joshi, Asavari and Venkataraman, Magesh and Desai, Nikesh and Bhatia, Dimple and Chaudhari, Sarika and Bose, Julie and Kolla, Lakshmi Sireesha and Deore, Vijaykumar and Yewalkar, Nilambari and Kumar, Sanjay and Sharma, Rajiv and Damre, Anagha and More, Avinash and Gill, Parkash and Sharma, Somesh
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 3742 - 3742
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18. Discovery of P3971 an Orally Efficacious Novel Anticancer Agent Targeting HIF-1 alpha and STAT3 Pathways
by Godse, Pallavi and Kumar, Pramod and Yewalkar, Nilambari and Deore, Vijaykumar and Lohar, Manoj and Mundada, Ramswaroop and Padgaonkar, Amol and Manohar, Sonal and Joshi, Asavari and Bhatia, Dimple and Desai, Nikesh and Damre, Anagha and Bhonde, Mandar and Joshi, Kalpana and Sharma, Rajiv and Kumar, Sanjay
Anti-Cancer Agents in Medicinal Chemistry, ISSN 1871-5206, 11/2013, Volume 13, Issue 9, pp. 1460 - 1466
Hypoxia-inducible factor-1 alpha (HIF-1 alpha ) and signal transducer and activator of transcription 3 (STAT3) are transcription factors and are activated in... 
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19. Full Text The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro
by Sumantran, Venil N and Chandwaskar, Rucha and Joshi, Asavari Kulkarni and Boddul, Sanjay and Patwardhan, Bhushan and Chopra, Arvind and Wagh, Ulhas V
Phytotherapy Research, ISSN 0951-418X, 10/2008, Volume 22, Issue 10, pp. 1342 - 1348
Using a validated explant model of in vitro cartilage damage, the effects of aqueous extracts of Withania somnifera (Ashwagandha) root and glucosamine sulphate... 
antiinflammatory | cartilage explants | Withania somnifera | chondroprotective | Cartilage explants | Chondroprotective | Antiinflammatory | MATRIX | CHEMISTRY, MEDICINAL | INTERLEUKIN-1-BETA | NITRIC-OXIDE | ARTICULAR CHONDROCYTES | PHARMACOLOGY & PHARMACY | PROSTAGLANDIN E-2 | Anti-Inflammatory Agents - pharmacology | Humans | Middle Aged | Plant Roots - chemistry | Aged | Cartilage - drug effects | Glucosamine - pharmacology | Osteoarthritis - pathology | In Vitro Techniques | Withania - chemistry
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20. Full Text The relationship between chondroprotective and antiinflammatory effects ofWithania somniferaroot and glucosamine sulphate on human osteoarthritic cartilagein vitro
by Sumantran, Venil N and Chandwaskar, Rucha and Joshi, Asavari Kulkarni and Boddul, Sanjay and Patwardhan, Bhushan and Chopra, Arvind and Wagh, Ulhas V
Phytotherapy Research, ISSN 0951-418X, 10/2008, Volume 22, Issue 10, pp. 1342 - 1348
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