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1. Full Text SLCO1B1 Variants and Statin-Induced Myopathy — A Genomewide Study
by Meade, T and Collins, R and Armitage, J and Parish, S and Barton, J and Bray, C and Wincott, E and Bowman, L and Clarke, R and Graham, I and Simpson, D and Warlow, C and Tobert, J and Musliner, T and Doll, R and Fox, K.M and Hill, C and Sandercock, P and Peto, R and Webster, J and Jamieson, J and Nixon, A and Lackie, S and Thompson, J and Brown, M and Blackwood, S and Morgan, M and Rhoden, W and Saeed, B and Houghton, M and Nicholson, A and Simpson, C and Hoburn, B and Cooper, I and Gallivan, A and Pickerell, E and Hancock, J and Watkinson, J and Burbridge, W and Kitchen, M and O'Leary, H and Verow, C and Meynell, L and Rollinson, L and Bain, S and Jones, A and Jewkes, C and Russon, C and Bateson, M and Gill, P and Stansbie, D and Bayly, G and Andrews, G and Halestrap, M and Meredith, J and Best, R and Appleyard, D and Wareing, H and Holmes, K and Holt, J and Kenyon, M and White, C and Khalifa, M and Newton, D and Wass, A and Watkinson, R and Creamer, J and Bethell, A and Butler, C and Washington, M and Weston, E and Machin, J and Cleaver, K and Wray, R and Sinclair, J and Van Aalst, A and Been, M and Mattu, R and Burke, A and Gill, L and Walton, E and Cowley, M and Robson, H and Graham, A and Rose, G and Kerr, M and Mallinson, J and Peascod, B and Scott, A and Donnelly, R and Gibson, T and Hannah, J and Henshaw, L and Margetts, M and Pearson, N and Frost, S and Murray, S and Marshall, A and Went, J and Simmonds, J and ... and The SEARCH Collaborative Group and SEARCH Collaborative Grp and SEARCH Collaborative Group and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The New England journal of medicine, ISSN 0028-4793, 08/2008, Volume 359, Issue 8, pp. 789 - 799
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Simvastatin - therapeutic use | Simvastatin - adverse effects | Humans | Middle Aged | Diabetes Mellitus - drug therapy | Genotype | Male | Risk | Genetic Markers | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Myocardial Infarction - drug therapy | Arterial Occlusive Diseases - drug therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Female | Aged | Myocardial Infarction - prevention & control | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 12 | Muscular Diseases - chemically induced | Muscular Diseases - genetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Complications and side effects | Analysis | Muscle diseases | Genetic aspects | Dosage and administration | Single nucleotide polymorphisms | Risk factors | Statins | Drug therapy | Kinases | Drug dosages | Cholesterol | Index Medicus | Abridged Index Medicus | MEDICIN OCH HÄLSOVETENSKAP | Single Nucleotide | genetics | Arterial Occlusive Diseases | pharmacokinetics | Muscular Diseases | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Chromosomes | MEDICAL AND HEALTH SCIENCES | Human | drug therapy | chemically induced | Simvastatin | prevention & control | Diabetes Mellitus | Myocardial Infarction | Pair 12 | Organic Anion Transporters | adverse effects | therapeutic use | Polymorphism
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2. Full Text Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial
by Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group and Study Effectiveness Additional Red and Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group and Sahlgrenska akademin and Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin and Institute of Medicine, Department of Emergeny and Cardiovascular Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The Lancet (British edition), ISSN 0140-6736, 2010, Volume 376, Issue 9753, pp. 1658 - 1669
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Myocardial Infarction - blood | Double-Blind Method | Simvastatin - administration & dosage | Humans | Middle Aged | Male | Hypercholesterolemia - drug therapy | Anticholesteremic Agents - adverse effects | Young Adult | Myocardial Infarction - complications | Anticholesteremic Agents - administration & dosage | Triglycerides - blood | Aged, 80 and over | Cholesterol, HDL - blood | Adult | Cholesterol, LDL - blood | Female | Hypercholesterolemia - complications | Aged | Heart attacks | Hospitals | Compliance | Cardiovascular disease | Kinases | Cholesterol | Statins | Index Medicus | Abridged Index Medicus | Anticholesteremic Agents | drug therapy | complications | Simvastatin | Triglycerides | MEDICIN OCH HÄLSOVETENSKAP | blood | 80 and over | HDL | Myocardial Infarction | Hypercholesterolemia | administration & dosage | LDL | adverse effects | MEDICAL AND HEALTH SCIENCES
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3. Full Text Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
by Liao, Hua-Xin and Lynch, Rebecca and Zhou, Tongqing and Gao, Feng and Munir Alam, S and Boyd, Scott D and Fire, Andrew Z and Roskin, Krishna M and Schramm, Chaim A and Zhang, Zhenhai and Zhu, Jiang and Shapiro, Lawrence and Mullikin, James C and Gnanakaran, S and Hraber, Peter and Wiehe, Kevin and Kelsoe, Garnett and Yang, Guang and Xia, Shi-Mao and Montefiori, David C and Parks, Robert and Lloyd, Krissey E and Scearce, Richard M and Soderberg, Kelly A and Cohen, Myron and Kamanga, Gift and Louder, Mark K and Tran, Lillian M and Chen, Yue and Cai, Fangping and Chen, Sheri and Moquin, Stephanie and Du, Xiulian and Gordon Joyce, M and Srivatsan, Sanjay and Zhang, Baoshan and Zheng, Anqi and Shaw, George M and Hahn, Beatrice H and Kepler, Thomas B and Korber, Bette T. M and Kwong, Peter D and Mascola, John R and Haynes, Barton F and Becker, Jesse and Benjamin, Betty and Blakesley, Robert and Bouffard, Gerry and Brooks, Shelise and Coleman, Holly and Dekhtyar, Mila and Gregory, Michael and Guan, Xiaobin and Gupta, Jyoti and Han, Joel and Hargrove, April and Ho, Shi-Ling and Johnson, Taccara and Legaspi, Richelle and Lovett, Sean and Maduro, Quino and Masiello, Cathy and Maskeri, Baishali and McDowell, Jenny and Montemayor, Casandra and Mulliki, James and Park, Morgan and Riebow, Nancy and Schandler, Karen and Schmidt, Brian and Sison, Christina and Stantripop, Mal and Thomas, James and Thomas, Pam and Vemulapalli, Meg and Young, Alice and NISC Comparative Sequencing Progra and NISC Comparative Sequencing Program
Nature (London), ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 469 - 476
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | HIV Envelope Protein gp120 - genetics | Clone Cells - cytology | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Crystallography, X-Ray | Neutralization Tests | Phylogeny | HIV Envelope Protein gp120 - metabolism | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | HIV-1 - chemistry | HIV Envelope Protein gp120 - chemistry | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Protein Structure, Tertiary | Amino Acid Sequence | CD4 Antigens - immunology | Africa | Cells, Cultured | Models, Molecular | Antibodies, Neutralizing - genetics | Cross Reactions - immunology | HIV Antibodies - chemistry | HIV-1 - classification | Antibodies, Monoclonal - genetics | Cell Lineage | HIV-1 - immunology | CD4 Antigens - chemistry | Antibodies, Neutralizing - chemistry | Epitopes - chemistry | HIV Antibodies - genetics | Mutation | Evolution, Molecular | Monoclonal antibodies | AIDS vaccines | Genetic aspects | Research | HIV (Viruses) | Properties | Proteins | Plasma | Infections | Patients | Binding sites | Crystal structure | Index Medicus
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4. Full Text Long-Term Effect of Diabetes and Its Treatment on Cognitive Function
by Jacobson, Alan M and Musen, Gail and Ryan, Christopher M and Silvers, Nancy and Cleary, Patricia and Waberski, Barbara and Burwood, Amanda and Weinger, Katie and Bayless, Meg and Dahms, William and Harth, Judith and The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group and DCCT EDIC Study Res Grp and Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group
The New England journal of medicine, ISSN 0028-4793, 05/2007, Volume 356, Issue 18, pp. 1842 - 1852
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | General aspects | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Glycated Hemoglobin A - analysis | Diabetic Coma - etiology | Diabetic Coma - psychology | Follow-Up Studies | Humans | Hypoglycemia - psychology | Middle Aged | Insulin - administration & dosage | Male | Cognition | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemic Agents - administration & dosage | Cognition Disorders - etiology | Diabetes Mellitus, Type 1 - blood | Seizures - etiology | Hypoglycemia - complications | Adult | Female | Psychological Tests | Diabetes Mellitus, Type 1 - psychology | Care and treatment | Cognition disorders | Hypoglycemia | Type 1 diabetes | Risk factors | Diabetes | Glucose | Cognitive ability | Index Medicus | Abridged Index Medicus
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5. Full Text Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection
by Yassine, Hadi M and Boyington, Jeffrey C and McTamney, Patrick M and Wei, Chih-Jen and Kanekiyo, Masaru and Kong, Wing-Pui and Gallagher, John R and Wang, Lingshu and Zhang, Yi and Joyce, M Gordon and Lingwood, Daniel and Moin, Syed M and Andersen, Hanne and Okuno, Yoshinobu and Rao, Srinivas S and Harris, Audray K and Kwong, Peter D and Mascola, John R and Nabel, Gary J and Graham, Barney S
Nature medicine, ISSN 1078-8956, 09/2015, Volume 21, Issue 9, pp. 1065 - 1070
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Nanoparticles | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Animals | Influenza Vaccines - immunology | Influenza A Virus, H5N1 Subtype - immunology | Vaccination | Female | Mice | Mice, Inbred BALB C | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Ferrets | Antibodies, Viral - blood | Influenza vaccines | Avian influenza | Prevention | Physiological aspects | Lectins | Research | B cells | Health aspects | Immunoglobulins | Influenza | Rodents | Index Medicus
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6. Full Text Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth
by Huang, Jinghe and Kang, Byong H and Ishida, Elise and Zhou, Tongqing and Griesman, Trevor and Sheng, Zizhang and Wu, Fan and Doria-Rose, Nicole A and Zhang, Baoshan and McKee, Krisha and O’Dell, Sijy and Chuang, Gwo-Yu and Druz, Aliaksandr and Georgiev, Ivelin S and Schramm, Chaim A and Zheng, Anqi and Joyce, M. Gordon and Asokan, Mangaiarkarasi and Ransier, Amy and Darko, Sam and Migueles, Stephen A and Bailer, Robert T and Louder, Mark K and Alam, S. Munir and Parks, Robert and Kelsoe, Garnett and Von Holle, Tarra and Haynes, Barton F and Douek, Daniel C and Hirsch, Vanessa and Seaman, Michael S and Shapiro, Lawrence and Mascola, John R and Kwong, Peter D and Connors, Mark and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Immunity (Cambridge, Mass.), ISSN 1074-7613, 11/2016, Volume 45, Issue 5, pp. 1108 - 1121
vaccine | envelope | antibody | HIV | immunotherapy | neutralizing | CD4-binding site | prophylaxis | resistance | structure | Life Sciences & Biomedicine | Immunology | Science & Technology | CD4-Positive T-Lymphocytes - immunology | HIV Envelope Protein gp120 - immunology | Antibody Specificity | HIV Infections - immunology | Antibodies, Neutralizing - immunology | Binding Sites, Antibody - immunology | HIV-1 - immunology | HIV Antibodies - immunology | Cell Separation | Humans | Viral antibodies | Allergy | Polysaccharides | Analysis | Communicable diseases | Antibodies | HIV (Viruses) | Allergic reaction | Medical research | Immunotherapy | Medicine, Experimental | Immunoglobulins | Cloning | Viruses | Glycoproteins | Vaccines | Patients | Proteins | Plasmids | Light | Phylogenetics | Bioinformatics | Binding sites | Index Medicus | BASIC BIOLOGICAL SCIENCES | 60 APPLIED LIFE SCIENCES
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