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1. Emerging optoelectronic applications
: 26-27 January 2004, San Jose, California, USA
2004, ISBN 0819452718, vii, 200
Book
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2. Full Text Break-induced replication repair of damaged forks induces genomic duplications in human cells
by Costantino, Lorenzo and Sotiriou, Sotirios K and Rantala, Juha K and Magin, Simon and Mladenov, Emil and Helleday, Thomas and Haber, James E and Iliakis, George and Kallioniemi, Olli P and Halazonetis, Thanos D
Science, ISSN 0036-8075, 2014, Volume 343, Issue 6166, pp. 88 - 91
In budding yeast, one-ended DNA double-strand breaks (DSBs) and damaged replication forks are repaired by break-induced replication (BIR), a homologous... 
YEAST | COMPLEX | DNA-POLYMERASE DELTA | INSTABILITY | CANCER DEVELOPMENT | STABILITY | MULTIDISCIPLINARY SCIENCES | ONCOGENE-INDUCED SENESCENCE | Gene Duplication | DNA Polymerase III - physiology | Cell Cycle | DNA Polymerase III - genetics | Neoplasms - genetics | Humans | Cyclin E - biosynthesis | DNA Replication - genetics | DNA Repair - genetics | Cyclin E - genetics | DNA Breaks, Double-Stranded | DNA replication | Research | Genetic recombination | DNA repair | Studies | Biotechnology | DNA damage | Genomics | Cell cycle
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3. Emerging optoelectronic applications
: 26-27 January, 2004, San Jose, California, USA
by Jabbour, Ghassan E and Rantala, Juha T and Society of Photo-optical Instrumentation Engineers
2004, Volume 5363.
Optoelectronic devices | Optoelectronics
Conference Proceeding
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4. Full Text A cell spot microarray method for production of high density siRNA transfection microarrays
by Rantala, Juha K and Mäkelä, Rami and Aaltola, Anna-Riina and Laasola, Petra and Mpindi, John-Patrick and Nees, Matthias and Saviranta, Petri and Kallioniemi, Olli
BMC Genomics, ISSN 1471-2164, 03/2011, Volume 12, Issue 1, pp. 162 - 162
Background: High-throughput RNAi screening is widely applied in biological research, but remains expensive, infrastructure-intensive and conversion of many... 
WIDE RNAI SCREEN | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROSTATE-CANCER CELLS | REVERSE TRANSFECTION | GENES | GENETICS & HEREDITY | IDENTIFICATION | MICROSCOPY | MAMMALIAN-CELLS | GENOME | ARRAYS | PROGRESSION | Microarray Analysis - methods | Prostatic Neoplasms - metabolism | RNA, Small Interfering - genetics | Transfection | Cell Survival | Humans | Gene Silencing | Male | Gene Expression Profiling | Tumor Cells, Cultured | Reverse Transcriptase Polymerase Chain Reaction | Usage | Methods | DNA microarrays | Proteins | Genes | Genomics | Cell cycle | Lipids | Libraries | Biology | Comparative analysis | Arrays | Prostate cancer | Experiments
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5. Full Text Direct Observations of Atmospheric Aerosol Nucleation
by Markku Kulmala and Jenni Kontkanen and Heikki Junninen and Katrianne Lehtipalo and Hanna E. Manninen and Tuomo Nieminen and Tuukka Petäjä and Mikko Sipilä and Siegfried Schobesberger and Pekka Rantala and Alessandro Franchin and Tuija Jokinen and Emma Järvinen and Mikko Äijälä and Juha Kangasluoma and Jani Hakala and Pasi P. Aalto and Pauli Paasonen and Jyri Mikkila and Joonas Vanhanen and Juho Aalto and Hannele Hakola and Ulla Makkonen and Taina Ruuskanen and Roy L. Mauldin and Jonathan Duplissy and Hanna Vehkamäki and Jaana Bäck and Aki Kortelainen and Ilona Riipinen and Theo Kurtán and Murray V. Johnston and James N. Smith and Mikael Ehn and Thomas F. Mentel and Kari E. J. Lehtinen and Ari Laaksonen and Veli-Matti Kerminen and Douglas R. Worsnop and Stockholms universitet and Naturvetenskapliga fakulteten and Institutionen för tillämpad miljövetenskap (ITM)
Science, ISSN 0036-8075, 2/2013, Volume 339, Issue 6122, pp. 943 - 946
Atmospheric nucleation is the dominant source of aerosol particles in the global atmosphere and an important player in aerosol climatic effects. The key steps... 
Nanoparticles | Molecules | Sulfuric acids | Nucleation | REPORTS | Vapors | Aerosols | Ions | Organic foods | Atmospherics | Diameters | RATES | NANOPARTICLES | CLUSTERS | MULTIDISCIPLINARY SCIENCES | GROWTH | SMEAR-II | SULFURIC-ACID | PARTICLE FORMATION | AMINE | CLIMATE | WATER | Atmospheric physics | Research | Observations | Atmospheric nucleation | Atmospheric chemistry | Atmospheric aerosols | Seeds | Clusters | Formations | Nanostructure | Naturvetenskap | Natural Sciences | Earth and Related Environmental Sciences | Geovetenskap och miljövetenskap
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6. Full Text Computation of Dynamic Polarizabilities and van der Waals Coefficients from Path-Integral Monte Carlo
by Tiihonen, Juha and Kylänpää, Ilkka and Rantala, Tapio T
Journal of Chemical Theory and Computation, ISSN 1549-9618, 11/2018, Volume 14, Issue 11, pp. 5750 - 5763
We demonstrate computation of total dynamic multipole polarizabilities using path-integral Monte Carlo method (PIMC). The PIMC approach enables accurate... 
DENSITY | DISPERSION COEFFICIENTS | ANALYTIC CONTINUATION | TIME-CORRELATION-FUNCTIONS | TEMPERATURE-DEPENDENCE | GROUND-STATE | QUANTUM | MULTIPOLE POLARIZABILITIES | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | CHEMISTRY, PHYSICAL | DIPOLE POLARIZABILITY | SIMULATIONS | Monte Carlo method | Computer simulation | Computation | Mathematical analysis | Temperature effects | Integrals | Spectra | Sharpness | Maximum entropy method | Maximum entropy
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7. DNA-barcoding clarifies species definitions of Finnish Apatania (trichoptera: Apataniidae)
by Salokannnel, Juha and Rantala, Markus J and Wahlberg, Niklas
Entomologica Fennica, ISSN 0785-8760, 05/2010, Volume 21, Issue 1, pp. 1 - 11
All the known 8 Finnish Apatania Kolenati species were analysed using the DNA barcoding method. The Finnish species were grouped in four clades; A. zonella... 
BUTTERFLIES | NYMPHALIDAE | MITOCHONDRIAL | ENTOMOLOGY | LARVAE
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8. Full Text Static field-gradient polarizabilities of small atoms and molecules at finite temperature
by Tiihonen, Juha and Kylänpää, Ilkka and Rantala, Tapio T
The Journal of Chemical Physics, ISSN 0021-9606, 11/2017, Volume 147, Issue 20, p. 204101
In this work, we propose new field-free estimators of static field-gradient polarizabilities for finite temperature path-integral Monte Carlo method. Namely,... 
CHEMISTRY, PHYSICAL | GROUND-STATE | H-2 | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | HYPERPOLARIZABILITIES | Coupling (molecular) | Monte Carlo method | Adiabatic flow | Dipoles | Computer simulation | Thermal coupling | Quadrupoles | Monte Carlo simulation
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9. Functional integration of opto-electro-mechanical devices and systems II
: 23-24 January 2002, San Jose, USA
by Descour, Michael R and Rantala, Juha T and Society of Photo-optical Instrumentation Engineers
2002, Volume 4647.
Microelectromechanical systems | Optoelectronic devices | Microelectronic packaging
Conference Proceeding
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10. Full Text Distinct roles of AKT isoforms in regulating β1-integrin activity, migration, and invasion in prostate cancer
by Virtakoivu, Reetta and Pellinen, Teijo and Rantala, Juha K and Perälä, Merja and Ivaska, Johanna
Molecular Biology of the Cell, ISSN 1059-1524, 09/2012, Volume 23, Issue 17, pp. 3357 - 3369
AKT1 and AKT2 kinases have been shown to play opposite roles in breast cancer migration and invasion. In this study, an RNA interference screen for integrin... 
Prostatic Neoplasms - metabolism | Up-Regulation | Proto-Oncogene Proteins c-met - biosynthesis | Receptor, Epidermal Growth Factor - biosynthesis | Cell Proliferation | Signal Transduction | Neoplasm Invasiveness | Humans | Male | MicroRNAs - biosynthesis | Cell Adhesion | Proto-Oncogene Proteins c-akt - genetics | Integrin beta1 - metabolism | Prostatic Neoplasms - genetics | Protein Isoforms - metabolism | RNA Interference | Cell Line, Tumor | RNA, Small Interfering | Proto-Oncogene Proteins c-akt - metabolism | Cell Movement | Protein Isoforms - genetics
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11. Full Text MiR-9, -31, and -182 Deregulation Promote Proliferation and Tumor Cell Survival in Colon Cancer
by Cekaite, Lina and Rantala, Juha K and Bruun, Jarle and Guriby, Marianne and Ågesen, Trude H and Danielsen, Stine A and Lind, Guro E and Nesbakken, Arild and Kallioniemi, Olli and Lothe, Ragnhild A and Skotheim, Rolf I
Neoplasia, ISSN 1476-5586, 2012, Volume 14, Issue 9, pp. 868 - IN21
Several microRNAs (miRNAs) are known to be deregulated in colon cancer, but the mechanisms behind their potential involvement on proliferation and tumor cell... 
Oncology | MIGRATION | PROFILES | INVASION | INSTABILITY | METASTASIS | ONCOLOGY | TRANSCRIPTION | MIR-31 | MICRORNA EXPRESSION | PROGRESSION | MIR-182 | Colonic Neoplasms - genetics | Reproducibility of Results | Cell Proliferation | HCT116 Cells | Humans | Gene Expression Regulation, Neoplastic | Cell Survival - genetics | Gene Expression Profiling | HT29 Cells | Cell Transformation, Neoplastic - genetics | Cell Line, Tumor | MicroRNAs - genetics | Genes, Tumor Suppressor | Oncogenes
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12. Full Text Combined prognostic value of CD274 (PD-L1)/PDCDI (PD-1) expression and immune cell infiltration in colorectal cancer as per mismatch repair status
by Ahtiainen, Maarit and Wirta, Erkki-Ville and Kuopio, Teijo and Seppälä, Toni and Rantala, Juha and Mecklin, Jukka-Pekka and Böhm, Jan
Modern Pathology, ISSN 0893-3952, 2019, Volume 32, Issue 6, pp. 866 - 883
The CD274 (programmed cell death ligand-1, PD-L1)/PDCD1 (programmed cell death-1, PD-1) pathway is crucial suppressor of the cytotoxic immune response.... 
SURVIVAL | SOLID TUMORS | DEATH 1 | SAFETY | GENETICS | MICROSATELLITE INSTABILITY | DEFICIENT | IMMUNOSCORE | PATHOLOGY | PD-1/PD-L1 BLOCKADE | LYMPHOCYTES | Yeast | Cell survival | Immune response | PD-1 protein | Tumor cells | Colorectal carcinoma | Colorectal cancer | Cytotoxicity | Microsatellite instability | DNA repair | Metastases | Cell death | Mismatch repair | PD-L1 protein | Apoptosis | Cancer
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13. Full Text DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer
by Lund, Riikka J and Huhtinen, Kaisa and Salmi, Jussi and Rantala, Juha and Nguyen, Elizabeth V and Moulder, Robert and Goodlett, David R and Lahesmaa, Riitta and Carpén, Olli
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1469 - 11
High-grade serous ovarian cancer is the most common ovarian cancer type. Although the combination of surgery and platinum-taxane chemotherapy provide an... 
TARGET | RNA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | RISK | CELL-LINES | IDENTIFICATION | DIFFERENTIAL EXPRESSION ANALYSIS | GENOME BROWSER | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Ovarian Neoplasms - genetics | DNA Methylation | Cisplatin - therapeutic use | Cell Line, Tumor | CpG Islands | Female | Ovarian Neoplasms - drug therapy | Transformation | Cell survival | Genomes | Drug resistance | Gene expression | Cisplatin | Ovarian cancer | Interleukin 6 | Chemotherapy | Molecular modelling | KLF4 protein | Platinum | Surgery | DNA methylation | Post-translation | Ascites | Ascites cells | CpG islands
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14. Full Text Clonal Evolution of MEK/MAPK Pathway Activating Mutations in a Metastatic Colorectal Cancer Case
by Lehtomaki, KI and Lahtinen, LI and Rintanen, N and Kuopio, T and Kholova, I and Makela, R and Rantala, JK and Kellokumpu-Lehtinen, PL and Kononen, J
ANTICANCER RESEARCH, ISSN 0250-7005, 11/2019, Volume 39, Issue 11, pp. 5867 - 5877
Background/Aim: The aim of this study was to examine clonal heterogeneity, to test the utility of liquid biopsy in monitoring disease progression and to... 
DABRAFENIB | BRAF(nonV600E) mutations | ex vivo drug screening | Colorectal cancer | SENSITIVITY | ctDNA | COLON-CANCER | MEK/MAPK pathway | INHIBITION | MELANOMA | GENOMICS | ONCOLOGY | BRAF MUTATIONS | RAF | RESISTANCE | liquid biopsy | VEMURAFENIB | Aggressive behavior | Colorectal carcinoma | MAP kinase | Metastasis | Drug screening | Metastases | Heterogeneity | Sensitivity | Next-generation sequencing | Biopsy | Dependence | Biomarkers | Mutation | Tumors | Cancer
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15. Full Text FZD4 as a mediator of ERG oncogene-induced WNT signaling and epithelial-to-mesenchymal transition in human prostate cancer cells
by Gupta, Santosh and Iljin, Kristiina and Sara, Henri and Mpindi, John Patrick and Mirtti, Tuomas and Vainio, Paula and Rantala, Juha and Alanen, Kalle and Nees, Matthias and Kallioniemi, Olli
Cancer Research, ISSN 0008-5472, 09/2010, Volume 70, Issue 17, pp. 6735 - 6745
TMPRSS2-ERG and other gene fusions involving ETS factors and genes with strong promoter elements are common in prostate cancer. Although ERG activation has... 
HETEROGENEITY | GENE FUSIONS | TRANSCRIPTS | INVASION | ACTIVATION | ONCOLOGY | TMPRSS2-ERG FUSION | E-CADHERIN | BETA-CATENIN | EXPRESSION | PROGRESSION | Transcriptional Regulator ERG | Prostatic Neoplasms - metabolism | Up-Regulation | Receptors, G-Protein-Coupled - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | Wnt Proteins - metabolism | Cadherins - biosynthesis | Gene Knockdown Techniques | Prostatic Neoplasms - genetics | Transfection | Trans-Activators - genetics | Trans-Activators - biosynthesis | Cadherins - genetics | Prostatic Neoplasms - pathology | Cell Adhesion - genetics | Gene Silencing | Frizzled Receptors - metabolism | Epithelial Cells - pathology | Signal Transduction - genetics | Integrin beta1 - biosynthesis | Frizzled Receptors - genetics | Cell Line, Tumor | Receptors, G-Protein-Coupled - genetics | Integrin beta1 - genetics | Mesoderm - pathology
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16. Full Text Micropulse diode laser trabeculoplasty – 180‐degree treatment
by Rantala, Elina and Välimäki, Juha
Acta Ophthalmologica, ISSN 1755-375X, 08/2012, Volume 90, Issue 5, pp. 441 - 444
. Purpose:  To evaluate the outcome of 180° micropulse diode laser trabeculoplasty (MDLT) in patients with open‐angle glaucoma. Methods:  A retrospective... 
180 degree | micropulse diode laser trabeculoplasty | trabeculoplasty | intraocular pressure | glaucoma | laser therapy | PILOT | OPEN-ANGLE GLAUCOMA | THERAPY | OPHTHALMOLOGY | Glaucoma, Open-Angle - surgery | Follow-Up Studies | Intraocular Pressure | Humans | Middle Aged | Antihypertensive Agents - administration & dosage | Lasers, Semiconductor - therapeutic use | Male | Treatment Outcome | Life Tables | Trabecular Meshwork - surgery | Glaucoma, Open-Angle - drug therapy | Aged, 80 and over | Female | Laser Therapy - methods | Aged | Retrospective Studies | Trabeculectomy - methods | Circuit components | Glaucoma | Ophthalmology | Lasers in surgery | Lasers | Analysis
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17. Full Text Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer
by Risom, Tyler and Langer, Ellen M and Chapman, Margaret P and Rantala, Juha and Fields, Andrew J and Boniface, Christopher and Alvarez, Mariano J and Kendsersky, Nicholas D and Pelz, Carl R and Johnson-Camacho, Katherine and Dobrolecki, Lacey E and Chin, Koei and Aswani, Anil J and Wang, Nicholas J and Califano, Andrea and Lewis, Michael T and Tomlin, Claire J and Spellman, Paul T and Adey, Andrew and Gray, Joe W and Sears, Rosalie C
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3815 - 17
Intratumoral heterogeneity in cancers arises from genomic instability and epigenomic plasticity and is associated with resistance to cytotoxic and targeted... 
GLIOBLASTOMA | THERAPY | TUMOR PROGRESSION | MEK INHIBITION | SUBTYPES | MULTIDISCIPLINARY SCIENCES | ACCESSIBILITY | CELL-LINES | IDENTIFICATION | EXPRESSION | CHEMOTHERAPY | Chromatin - metabolism | Humans | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Mice, SCID | Molecular Targeted Therapy | Breast Neoplasms - drug therapy | Azepines - pharmacology | Triazoles - pharmacology | Animals | Breast Neoplasms - pathology | Triple Negative Breast Neoplasms - pathology | Cell Line, Tumor | Cell Plasticity | Female | Mice, Inbred NOD | Cell Differentiation | TOR protein | Subpopulations | Stability | Architecture | Xenotransplantation | Cytotoxicity | Breast cancer | Pharmacology | Chemical compounds | 1-Phosphatidylinositol 3-kinase | Chromatin remodeling | Genomic instability | Heterogeneity | Inhibitors | Robustness (mathematics) | Cell death | Plasticity | Xenografts | Plastic properties | Differentiation | Cancer
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18. Full Text Metformin Improves Pregnancy and Live-Birth Rates in Women with Polycystic Ovary Syndrome (PCOS): A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial
by Morin-Papunen, Laure and Rantala, Anni S and Unkila-Kallio, Leila and Tiitinen, Aila and Hippeläinen, Maritta and Perheentupa, Antti and Tinkanen, Helena and Bloigu, Risto and Puukka, Katri and Ruokonen, Aimo and Tapanainen, Juha S
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2012, Volume 97, Issue 5, pp. 1492 - 1500
Background: The role of metformin in the treatment of infertility in women with polycystic ovary syndrome (PCOS) is still controversial. Objective and... 
THERAPY | INSULIN-RESISTANCE | OVULATION | ENDOCRINOLOGY & METABOLISM | INFERTILITY | RISK | CLOMIPHENE CITRATE | INDUCTION | Metformin - therapeutic use | Abortion, Spontaneous - prevention & control | Double-Blind Method | Humans | Treatment Outcome | Pregnancy | Polycystic Ovary Syndrome - complications | Infertility, Female - drug therapy | Infertility, Female - etiology | Adult | Female | Birth Rate | Pregnancy Rate
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