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The Lancet (British edition), ISSN 0140-6736, 2010, Volume 375, Issue 9716, pp. 735 - 742
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2012, Volume 366, Issue 1, pp. 20 - 33
In this trial, vorapaxar, a protease-activated–receptor 1 antagonist that inhibits thrombin-induced platelet activation, was not effective in reducing the... 
MEDICINE, GENERAL & INTERNAL | PLACEBO | GLYCOPROTEIN IIB/IIIA INHIBITORS | CLOPIDOGREL | TASK-FORCE | SAFETY | DOUBLE-BLIND | ANTIPLATELET THERAPY | Follow-Up Studies | Angioplasty | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Pyridines - adverse effects | Cardiovascular Diseases - mortality | Female | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Pyridines - therapeutic use | Double-Blind Method | Receptor, PAR-1 - antagonists & inhibitors | Kaplan-Meier Estimate | Combined Modality Therapy | Lactones - adverse effects | Lactones - therapeutic use | Acute Coronary Syndrome - drug therapy | Intracranial Hemorrhages - chemically induced | Coronary Artery Bypass | Acute Coronary Syndrome - therapy | Aged | Hemorrhage - chemically induced | Antagonists (Biochemistry) | Drugs | Dose-response relationship (Biochemistry) | Dosage and administration | Product/Service Evaluations | Drug therapy | Coronary heart disease | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | Proteinase-activated receptor 1 | Thrombin | Cardiovascular disease | Hemorrhage | Bleeding | Investigations | Manuscripts | Ischemia | Blood platelets | Acute coronary syndromes | Research centers | Malalties cardiovasculars | Bypass cardiopulmonar | Medicaments | Bypass cardiopulmonary | Plaquetes sanguínies | Cardiovascular diseases
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2014, Volume 63, Issue 12, pp. 1200 - 1210
Journal Article
by Porcu, Eleonora and Medici, Marco and Pistis, Giorgio and Volpato, Claudia B and Wilson, Scott G and Cappola, Anne R and Bos, Steffan D and Deelen, Joris and den Heijer, Martin and Freathy, Rachel M and Lahti, Jari and Liu, Chunyu and Lopez, Lorna M and Nolte, Ilja M and O'Connell, Jeffrey R and Tanaka, Toshiko and Trompet, Stella and Arnold, Alice and Bandinelli, Stefania and Beekman, Marian and Böhringer, Stefan and Brown, Suzanne J and Buckley, Brendan M and Camaschella, Clara and de Craen, Anton J. M and Davies, Gail and de Visser, Marieke C. H and Ford, Ian and Forsen, Tom and Frayling, Timothy M and Fugazzola, Laura and Gögele, Martin and Hattersley, Andrew T and Hermus, Ad R and Hofman, Albert and Houwing-Duistermaat, Jeanine J and Jensen, Richard A and Kajantie, Eero and Kloppenburg, Margreet and Lim, Ee M and Masciullo, Corrado and Mariotti, Stefano and Minelli, Cosetta and Mitchell, Braxton D and Nagaraja, Ramaiah and Netea-Maier, Romana T and Palotie, Aarno and Persani, Luca and Piras, Maria G and Psaty, Bruce M and Räikkönen, Katri and Richards, J. Brent and Rivadeneira, Fernando and Sala, Cinzia and Sabra, Mona M and Sattar, Naveed and Shields, Beverley M and Soranzo, Nicole and Starr, John M and Stott, David J and Sweep, Fred C. G. J and Usala, Gianluca and van der Klauw, Melanie M and van Heemst, Diana and van Mullem, Alies and H.Vermeulen, Sita and Visser, W. Edward and Walsh, John P and Westendorp, Rudi G. J and Widen, Elisabeth and Zhai, Guangju and Cucca, Francesco and Deary, Ian J and Eriksson, Johan G and Ferrucci, Luigi and Fox, Caroline S and Jukema, J. Wouter and Kiemeney, Lambertus A and Pramstaller, Peter P and Schlessinger, David and Shuldiner, Alan R and Slagboom, Eline P and Uitterlinden, André G and Vaidya, Bijay and Visser, Theo J and Wolffenbuttel, Bruce H. R and Meulenbelt, Ingrid and Rotter, Jerome I and Spector, Tim D and Hicks, Andrew A and Toniolo, Daniela and Sanna, Serena and Peeters, Robin P and Naitza, Silvia
PLoS genetics, ISSN 1553-7404, 2013, Volume 9, Issue 2, p. e1003266
Journal Article
by Gunter Schumann and Chunyu Liu and Paul O’Reilly and He Gao and Parkyong Song and Bing Xu and Barbara Ruggeri and Najaf Amin and Tianye Jia and Sarah Preis and Marcelo Segura Lepe and Shizuo Akira and Caterina Barbieri and Sebastian Baumeister and Stephane Cauchi and Toni-Kim Clarke and Stefan Enroth and Kristar Fische and Jenni Hällfors and Sarah E. Harris and Saskia Hieber and Edith Hofer and Jouke-Jan Hottenga and Åsa Johansson and Peter K. Joshi and Niina Kaartinen and Jaana Laitinen and Rozenn Lemaitre and Anu Loukola and Jian’an Luan and Leo-Pekka Lyytikäinen and Massimo Mangino and Ani Manichaikul and Hamdi Mbarek and Yuri Milaneschi and Alireza Moayyeri and Kenneth Mukamal and Christopher Nelson and Jennifer Nettleton and Eemil Partinen and Rajesh Rawal and Antonietta Robino and Lynda Rose and Cinzia Sala and Takashi Satoh and Reinhold Schmidt and Katharina Schraut and Robert Scott and Albert Vernon Smith and John M. Starr and Alexander Teumer and Stella Trompet and André G. Uitterlinden and Cristina Venturini and Anne-Claire Vergnaud and Niek Verweij and Veronique Vitart and Dragana Vuckovic and Juho Wedenoja and Loic Yengo and Bing Yu and Weihua Zhang and Jing Hua Zhao and Dorret I. Boomsma and John Chambers and Daniel I. Chasman and Toniolo Daniela and Eco de Geus and Ian Deary and Johan G. Eriksson and Tõnu Esko and Volker Eulenburg and Oscar H. Franco and Philippe Froguel and Christian Gieger and Hans J. Grabe and Vilmundur Gudnason and Ulf Gyllensten and Tamara B. Harris and Anna-Liisa Hartikainen and Andrew C. Heath and Lynne Hocking and Albert Hofman and Cornelia Huth and Marjo-Riitta Jarvelin and J. Wouter Jukema and Jaakko Kaprio and Jaspal S. Kooner and Zoltan Kutalik and Jari Lahti and Claudia Langenberg and Terho Lehtimäki and Yongmei Liu and Pamela A. F. Madden and Nicholas Martin and Alanna Morrison and Brenda Penninx and Nicola Pirastu and Bruce Psaty and Olli Raitakari and ...
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2016, Volume 113, Issue 50, pp. 14372 - 14377
Journal Article
The American heart journal, ISSN 0002-8703, 2014, Volume 168, Issue 5, pp. 682 - 689.e1
Journal Article
Journal Article
by Joshi, Peter K and Pirastu, Nicola and Kentistou, Katherine A and Fischer, Krista and Hofer, Edith and Schraut, Katharina E and Clark, David W and Nutile, Teresa and Barnes, Catriona L. K and Timmers, Paul R. H. J and Shen, Xia and Gandin, Ilaria and McDaid, Aaron F and Hansen, Thomas Folkmann and Gordon, Scott D and Giulianini, Franco and Boutin, Thibaud S and Abdellaoui, Abdel and Zhao, Wei and Medina-Gomez, Carolina and Bartz, Traci M and Trompet, Stella and Lange, Leslie A and Raffield, Laura and van der Spek, Ashley and Galesloot, Tessel E and Proitsi, Petroula and Yanek, Lisa R and Bielak, Lawrence F and Payton, Antony and Murgia, Federico and Concas, Maria Pina and Biino, Ginevra and Tajuddin, Salman M and Seppälä, Ilkka and Amin, Najaf and Boerwinkle, Eric and Børglum, Anders D and Campbell, Archie and Demerath, Ellen W and Demuth, Ilja and Faul, Jessica D and Ford, Ian and Gialluisi, Alessandro and Gögele, Martin and Graff, MariaElisa and Hingorani, Aroon and Hottenga, Jouke-Jan and Hougaard, David M and Hurme, Mikko A and Ikram, M. Arfan and Jylhä, Marja and Kuh, Diana and Ligthart, Lannie and Lill, Christina M and Lindenberger, Ulman and Lumley, Thomas and Mägi, Reedik and Marques-Vidal, Pedro and Medland, Sarah E and Milani, Lili and Nagy, Reka and Ollier, William E. R and Peyser, Patricia A and Pramstaller, Peter P and Ridker, Paul M and Rivadeneira, Fernando and Ruggiero, Daniela and Saba, Yasaman and Schmidt, Reinhold and Schmidt, Helena and Slagboom, P. Eline and Smith, Blair H and Smith, Jennifer A and Sotoodehnia, Nona and Steinhagen-Thiessen, Elisabeth and van Rooij, Frank J. A and Verbeek, André L and Vermeulen, Sita H and Vollenweider, Peter and Wang, Yunpeng and Werge, Thomas and Whitfield, John B and Zonderman, Alan B and Lehtimäki, Terho and Evans, Michele K and Pirastu, Mario and Fuchsberger, Christian and Bertram, Lars and Pendleton, Neil and Kardia, Sharon L. R and Ciullo, Marina and Becker, Diane M and Wong, Andrew and Psaty, Bruce M and van Duijn, Cornelia M and Wilson, James G and Jukema, J. Wouter and Kiemeney, Lambertus and Uitterlinden, André G and ...
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, pp. 910 - 13
Journal Article