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PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e57469
Interleukin-27 (IL-27) is a pleiotropic cytokine but its immunosuppressive effects predominate during many in vivo immunological challenges. Despite this,... 
ADAPTIVE IMMUNITY | BET | COMPLETE REGRESSION | TH1 RESPONSES | CARCINOGENESIS | MULTIDISCIPLINARY SCIENCES | BIOLOGY | REGULATORY T-CELLS | IL-27 | ANTITUMOR | CUTTING EDGE | CD8-Positive T-Lymphocytes - pathology | Neoplasms, Experimental - therapy | Male | Signal Transduction - genetics | T-Lymphocytes, Regulatory - pathology | Mice, Knockout | T-Lymphocytes, Regulatory - immunology | Neoplasms, Experimental - pathology | Interleukins - genetics | Signal Transduction - immunology | Animals | Interferon-gamma - immunology | Interleukins - immunology | Neoplasms, Experimental - immunology | Neoplasms, Experimental - genetics | Immune Tolerance - genetics | Receptors, Cytokine - immunology | Mice | Interferon-gamma - genetics | CD8-Positive T-Lymphocytes - immunology | Receptors, Cytokine - genetics | Sarcoma | Interleukins | Development and progression | Genetic aspects | Interferon | Biological response modifiers | T cells | Cancer | Cell culture | Animal models | Carcinoma | CD8 antigen | Interleukin | Fibrosarcoma | Cytotoxicity | Nervous system | Lymphocytes T | Immunity | Interleukin 27 | Carcinogens | Immunology | Lymphocytes | Rodents | Mammary gland | Medical research | Antigens | Immune response | Cytokines | Immunosurveillance | Pharmacology | Inflammation | Chemical compounds | CD4 antigen | Signaling | Immunosuppression | Gene therapy | Tumors
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3120 - 13
High-throughput single-cell RNA sequencing is a powerful technique but only generates short reads from one end of a cDNA template, limiting the reconstruction... 
HETEROGENEITY | RECOMBINATION | RNA-SEQ | RECONSTRUCTION | MULTIDISCIPLINARY SCIENCES | RECEPTOR | CHAINS | EXPRESSION | CANCER | T-CELLS | BREAST | Alternative splicing | Antigens | Profiling | Tracking | Transcription | Breast cancer | Lymphocytes T | Nucleotides | Gene expression | B-cell receptor | Immunity | Lymph nodes | Gene sequencing | Drainage | T-cell receptor | Receptors | Lymphocytes B | Lymphocytes | Evolution
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 17, Issue 2, pp. 121 - 134
Chronically activated leukocytes recruited to premalignant tissues functionally contribute to cancer development; however, mechanisms underlying pro- versus... 
CELLCYCLE | MOLIMMUNO | CELLIMMUNO | PRIMARY TUMORS | ANGIOGENESIS | ONCOLOGY | MACROPHAGES | MAST-CELLS | TIE2-EXPRESSING MONOCYTES | GROWTH | HUMORAL IMMUNITY | K14-HPV16 TRANSGENIC MICE | RECEPTORS | CANCER
Journal Article
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 2015, Volume 5, Issue 1, pp. 35 - 42
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2007, Volume 13, Issue 11, pp. 1333 - 1340
Journal Article
Genes and Development, ISSN 0890-9369, 10/2013, Volume 27, Issue 19, pp. 2086 - 2098
Journal Article
Journal Article
OncoImmunology, ISSN 2162-4011, 08/2013, Volume 2, Issue 8, p. e25409
We have recently been the first to demonstrate that interleukin (IL)-27 protects against the emergence and progression of autochthonous tumors. Accumulating... 
3-methylcholanthrene | interleukin-27 | polyomavirus middle T antigen (PyMT)-induced mammary carcinoma | Tregs | interferon γ | Interferon γ | Polyomavirus middle T antigen (PyMT)-induced mammary carcinoma | Interleukin-27 | ADAPTIVE IMMUNITY | BREAST-CANCER | INTERLEUKIN-2 | interferon gamma | THERAPY | ONCOLOGY | TUMOR-REGRESSION | IMMUNOLOGY | Author's View
Journal Article
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 05/2010, Volume 3, Issue 5-6, pp. 317 - 332
Innate regulatory networks within organs maintain tissue homeostasis and facilitate rapid responses to damage. We identified a novel pathway regulating vessel... 
INTERSTITIAL FLUID PRESSURE | GROWTH-FACTOR-BETA | ACTIVATION | TYPE-1 MATRIX-METALLOPROTEINASE | SOLID TUMORS | ANGIOGENESIS | TRANSFORMING GROWTH-FACTOR-BETA-1 | MOUSE MODEL | CAPILLARY ENDOTHELIAL-CELLS | I COLLAGEN | PATHOLOGY | CELL BIOLOGY
Journal Article