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Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 04/2019, Volume 20, Issue 4, pp. 197 - 197
How the fertilized egg develops into a complex organism consisting of many different cell types is one of the great mysteries of biology. This is even more so... 
CELL BIOLOGY | Genetic research | Gene expression | Embryonic development | Genotype & phenotype | Developmental biology
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1920, pp. 129 - 141
Embryonic development is heavily dependent on temporally and spatially restricted gene expression. Spatially resolved measurements of gene expression are... 
Developmental patterning | Gene expression mapping | mRNA sequencing | Spatial transcriptomics | Morphogen gradients | Local gene expression | Index Medicus
Journal Article
Nature Biotechnology, ISSN 1087-0156, 06/2018, Volume 36, Issue 5, pp. 469 - 473
A key goal of developmental biology is to understand how a single cell is transformed into a full-grown organism comprising many different cell types.... 
PROGENITORS | STEM-CELLS | DESIGN | SINGLE CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | TRACKING | DYNAMICS | MODEL | ZEBRAFISH EMBRYO | EXPRESSION | Methods | Nucleotide sequencing | DNA sequencing | Trees | CRISPR | Larvae | Taxonomy | Developmental biology | Liver | Bar codes | Transgenic | Telencephalon | Editing | Zebrafish | Genomes | Gene expression | Ribonucleic acid--RNA | Gene sequencing | Scars | Computer applications | Nuclease | Pancreas | Index Medicus
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 08/2016
By employing the sensitivity of single molecule fluorescent in situ hybridisation (smFISH) we have precisely quantified the levels and defined the temporal and... 
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2015, Volume 58, Issue 4, pp. 563 - 564
Two publications in the current issue of introduce novel methods for high-throughput single-cell transcriptomics by using droplet microfluidics and... 
RNA-SEQ | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Microfluidic Analytical Techniques | Genome-Wide Association Study | Animals | Embryonic Stem Cells - cytology | Retina - cytology | Single-Cell Analysis - methods | Gene Expression Profiling - methods | Microfluidics | Index Medicus
Journal Article
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 09/2015, Volume 11, Issue 9, p. e1005531
The chromosomal program of meiotic prophase, comprising events such as laying down of meiotic cohesins, synapsis between homologs, and homologous... 
Journal Article
Developmental Cell, ISSN 1534-5807, 12/2018, Volume 47, Issue 6, pp. 801 - 813.e6
To advance our understanding of the genetic programs that drive cell and tissue specialization, it is necessary to obtain a comprehensive overview of gene... 
mRNA sequencing | germline | spatial transcriptomics | C. elegans | CEL-seq | sperm | male fertility | C. elegans | READ ALIGNMENT | SPERM | GERM-LINE | VESICLES | MALE MATING-BEHAVIOR | NEURONS | NEUROPEPTIDE GENE | DEVELOPMENTAL BIOLOGY | NEMATODE | FAMILY | CELL BIOLOGY | Index Medicus
Journal Article
Angewandte Chemie - International Edition, ISSN 1433-7851, 04/2010, Volume 49, Issue 19, pp. 3306 - 3309
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 34, pp. 14361 - 14366
The eukaryotic signaling protein calmodulin (CaM) can bind to more than 300 known target proteins to regulate numerous functions in our body in a... 
Proteins | Potential energy | Cantilevers | Spectroscopy | Molecules | Calcium | Amino acids | Ligands | Kinetics | Velocity | Atomic force microscopy | Protein engineering | Protein-target interactions | MECHANICAL STABILITY | COMPLEX | DOMAIN | RECOGNITION | MULTIDISCIPLINARY SCIENCES | KINASE | CONFORMATIONAL DYNAMICS | atomic force microscopy | protein-target interactions | protein engineering | PEPTIDES | CALCIUM-BINDING | PROTEINS | Calmodulin - genetics | Myosin-Light-Chain Kinase - genetics | Calcium - metabolism | Humans | Molecular Sequence Data | Calcium - chemistry | Microscopy, Atomic Force | Calmodulin - chemistry | Binding Sites | Myosin-Light-Chain Kinase - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Muscle, Skeletal - enzymology | Calmodulin - metabolism | Protein Structure, Secondary | Myosin-Light-Chain Kinase - metabolism | Models, Molecular | Calcium-Calmodulin-Dependent Protein Kinase Kinase - genetics | Protein Folding | Calcium-Calmodulin-Dependent Protein Kinase Kinase - chemistry | Animals | Calcium-Calmodulin-Dependent Protein Kinase Kinase - metabolism | Protein Binding | Protein Conformation | Molecular spectroscopy | Chemical properties | Research | Observations | Calmodulin | Protein-protein interactions | Signal transduction | Eukaryotes | Peptides | Spectrum analysis | Binding sites | Index Medicus | Biological Sciences | protein–target interactions
Journal Article