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by Fuchsberger, Christian and Flannick, Jason and Teslovich, Tanya M and Mahajan, Anubha and Agarwala, Vineeta and Gaulton, Kyle J and Ma, Clement and Fontanillas, Pierre and Moutsianas, Loukas and McCarthy, Davis J and Rivas, Manuel A and Perry, John R. B and Sim, Xueling and Blackwell, Thomas W and Robertson, Neil R and Rayner, N. William and Cingolani, Pablo and Locke, Adam E and Fernandez Tajes, Juan and Highland, Heather M and Dupuis, Josee and Chines, Peter S and Lindgren, Cecilia M and Hartl, Christopher and Jackson, Anne U and Chen, Han and Huyghe, Jeroen R and van de Bunt, Martijn and Pearson, Richard D and Kumar, Ashish and Müller-Nurasyid, Martina and Grarup, Niels and Stringham, Heather M and Gamazon, Eric R and Lee, Jaehoon and Chen, Yuhui and Scott, Robert A and Below, Jennifer E and Chen, Peng and Huang, Jinyan and Go, Min Jin and Stitzel, Michael L and Pasko, Dorota and Parker, Stephen C. J and Varga, Tibor V and Green, Todd and Beer, Nicola L and Day-Williams, Aaron G and Ferreira, Teresa and Fingerlin, Tasha and Horikoshi, Momoko and Hu, Cheng and Huh, Iksoo and Ikram, Mohammad Kamran and Kim, Bong-Jo and Kim, Yongkang and Kim, Young Jin and Kwon, Min-Seok and Lee, Juyoung and Lee, Selyeong and Lin, Keng-Han and Maxwell, Taylor J and Nagai, Yoshihiko and Wang, Xu and Welch, Ryan P and Yoon, Joon and Zhang, Weihua and Barzilai, Nir and Voight, Benjamin F and Han, Bok-Ghee and Jenkinson, Christopher P and Kuulasmaa, Teemu and Kuusisto, Johanna and Manning, Alisa and Ng, Maggie C. Y and Palmer, Nicholette D and Balkau, Beverley and Stancáková, Alena and Abboud, Hanna E and Boeing, Heiner and Gieaitis, Vilmantas and Prabhakaran, Dorairaj and Gottesman, Omri and Scott, James and Carey, Jason and Kwan, Phoenix and Grant, George and Smith, Joshua D and Neale, Benjamin M and Purcell, Shaun and Butterworth, Adam S and Howson, Joanna M. M and Lee, Heung Man and Lu, Yingchang and Kwak, Soo-Heon and Zhao, Wei and Danesh, John and Lam, Vincent K. L and Park, Kyong Soo and Saleheen, Danish and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2016, Volume 536, Issue 7614, pp. 41 - +
Journal Article
Diabetologia, ISSN 0012-186X, 9/2014, Volume 57, Issue 9, pp. 1859 - 1868
Journal Article
by Van Zuydam, Natalie R and Van Zuydam, Natalie R and Ahlqvist, Emma and Ahlqvist, Emma and Sandholm, Niina and Sandholm, Niina and Deshmukh, Harshal and William Rayner, N and Rayner, N. William and Abdalla, Moustafa and Abdalla, Moustafa and Ladenvall, Claes and Ladenvall, Claes and Ziemek, Daniel and Fauman, Eric and Robertson, Neil R and McKeigue, Paul M and McKeigue, Paul M and Valo, Erkka and Valo, Erkka and Forsblom, Carol and Forsblom, Carol and Harjutsalo, Valma and Harjutsalo, Valma and Perna, Annalisa and Perna, Annalisa and Rurali, Erica and Rurali, Erica and Marcovecchio, M. Loredana and Loredana Marcovecchio, M and Igo, Robert P and Igo, Robert P and Salem, Rany M and Salem, Rany M and Perico, Norberto and Perico, Norberto and Lajer, Maria and Käräjämäki, Annemari and Imamura, Minako and Imamura, Minako and Kubo, Michiaki and Kubo, Michiaki and Takahashi, Atsushi and Takahashi, Atsushi and Sim, Xueling and Liu, Jianjun and Liu, Jianjun and Van Dam, Rob M and Van Dam, Rob M and Jiang, Guozhi and Tam, Claudia H.T and Luk, Andrea O.Y and Lee, Heung Man and Lim, Cadmon K.P and Szeto, Cheuk Chun and Szeto, Cheuk Chun and So, Wing Yee and Chan, Juliana C.N and Chan, Juliana C.N and Ang, Su Fen and Dorajoo, Rajkumar and Dorajoo, Rajkumar and Wang, Ling and Wang, Ling and Clara, Tan Si Hua and McKnight, Amy-Jayne and McKnight, Amy-Jayne and Duffy, Seamus and Duffy, Seamus and Warren, Warren and Pezzolesi, Marcus G and Pezzolesi, Marcus G and Marre, Michel and Gyorgy, Beata and Marre, Michel and Gyorgy, Beata and Hadjadj, Samy and Hadjadj, Samy and Hiraki, Linda T and Hiraki, Linda T and Ahluwalia, Tarunveer S and Almgren, Peter and Ahluwalia, Tarunveer S and Schulz, Christina-Alexandra and Almgren, Peter and Schulz, Christina-Alexandra and Orho-Melander, Marju and Linneberg, Allan and Orho-Melander, Marju and Linneberg, Allan and Christensen, Cramer and Christensen, Cramer and Witte, Daniel R and Grarup, Niels and Witte, Daniel R and Grarup, Niels and Brandslund, Ivan and Melander, Olle and Brandslund, Ivan and Paterson, Andrew D and ... and SUrrogate Markers Micro Macrovascu and Warren 3 Genetics Kidneys Diabet and Hong Kong Diabet Registry Theme and Finnish Diabetic Nephropathy Study and Epidemiology Diabet Interventions and Diabet Control Complications Trial and GENIE GEnetics Nephropathy Int and Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group and Hong Kong Diabetes Registry Theme-based Research Scheme Project Group and Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group and GENIE (GEnetics of Nephropathy an International Effort) Consortium and Finnish Diabetic Nephropathy Study (FinnDiane) and SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium
Diabetes, ISSN 0012-1797, 07/2018, Volume 67, Issue 7, pp. 1414 - 1427
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 05/2018, Volume 6, Issue 5, pp. 361 - 369
Journal Article
by Manning, Alisa and Highland, Heather M and Gasser, Jessica and Sim, Xueling and Tukiainen, Taru and Fontanillas, Pierre and Grarup, Niels and Rivas, Manuel A and Mahajan, Anubha and Locke, Adam E and Cingolani, Pablo and Pers, Tune H and Viñuela, Ana and Brown, Anew A and Wu, Ying and Flannick, Jason and Fuchsberger, Christian and Gamazon, Eric R and Gaulton, Kyle J and Im, Hae Kyung and Teslovich, Tanya M and Blackwell, Thomas W and Bork-Jensen, Jette and Burtt, Noël P and Chen, Yuhui and Green, Todd and Hartl, Christopher and Kang, Hyun Min and Kumar, Ashish and Ladenvall, Claes and Ma, Clement and Moutsianas, Loukas and Pearson, Richard D and Perry, John R. B and Rayner, N. William and Robertson, Neil R and Scott, Laura J and van de Bunt, Martijn and Eriksson, Johan G and Jula, Antti and Koskinen, Seppo and Lehtimäki, Terho and Palotie, Aarno and Raitakari, Olli T and Jacobs, Suzanne B. R and Wessel, Jennifer and Chu, Auey Y and Scott, Robert A and Goodarzi, Mark O and Blancher, Christine and Buck, Gemma and Buck, David and Chines, Peter S and Gabriel, Stacey and Gjesing, Anette P and Groves, Christopher J and Hollensted, Mette and Huyghe, Jeroen R and Jackson, Anne U and Jun, Goo and Justesen, Johanne Marie and Mangino, Massimo and Murphy, Jacquelyn and Neville, Matt and Onofrio, Robert and Small, Kerrin S and Stringham, Heather M and Trakalo, Joseph and Banks, Eric and Carey, Jason and Carneiro, Mauricio O and DePristo, Mark and Farjoun, Yossi and Fennell, Timothy and Goldstein, Jacqueline I and Grant, George and Hrabé de Angelis, Martin and Maguire, Jared and Neale, Benjamin M and Poplin, Ryan and Purcell, Shaun and Schwarzmayr, Thomas and Shakir, Khalid and Smith, Joshua D and Strom, Tim M and Wieland, Thomas and Lindstrom, Jaana and Brandslund, Ivan and Christensen, Cramer and Surdulescu, Gabriela L and Lakka, Timo A and Doney, Alex S. F and Nilsson, Peter and Wareham, Nicholas J and Langenberg, Claudia and Varga, Tibor V and Franks, Paul W and Rolandsson, Olov and Rosengren, Anders H and Farook, Vidya S and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
Diabetes, ISSN 0012-1797, 2017, Volume 66, Issue 7, pp. 2019 - 2032
To identify novel coding association signals and facilitate characterization of mechanisms influencing glycemic traits and type 2 diabetes risk, we analyzed... 
Fasting | Diabetes mellitus | AKT2 protein | Homeostasis | Homology | Glucose | Insulin | Proteins | Genotype & phenotype | Genotyping | Gene frequency | Risk assessment | Pleckstrin | Alleles | Diabetes | Mutation | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
by Cousminer, Diana L and Cousminer, Diana L and Ahlqvist, Emma and Ahlqvist, Emma and Mishra, Rajashree and Mishra, Rajashree and Andersen, Mette K and Andersen, Mette K and Chesi, Alessandra and Chesi, Alessandra and Hawa, Mohammad I and Hawa, Mohammad I and Davis, Asa and Davis, Asa and Hodge, Kenyaita M and Hodge, Kenyaita M and Bradfield, Jonathan P and Bradfield, Jonathan P and Zhou, Kaixin and Zhou, Kaixin and Guy, Vanessa C and Guy, Vanessa C and Åkerlund, Mikael and Akerlund, Mikael and Wod, Mette and Wod, Mette and Fritsche, Lars G and Fritsche, Lars G and Vestergaard, Henrik and Vestergaard, Henrik and Snyder, James and Snyder, James and Højlund, Kurt and Højlund, Kurt and Linneberg, Allan and Linneberg, Allan and Käräjämäki, Annemari and Käräjämäki, Annemari and Brandslund, Ivan and Brandslund, Ivan and Kim, Cecilia E and Kim, Cecilia E and Witte, Daniel and Witte, Daniel and Sørgjerd, Elin Pettersen and Sørgjerd, Elin Pettersen and Brillon, David J and Brillon, David J and Pedersen, Oluf and Pedersen, Oluf and Beck-Nielsen, Henning and Beck-Nielsen, Henning and Grarup, Niels and Grarup, Niels and Pratley, Richard E and Pratley, Richard E and Rickels, Michael R and Rickels, Michael R and Vella, Adrian and Vella, Adrian and Ovalle, Fernando and Ovalle, Fernando and Melander, Olle and Melander, Olle and Harris, Ronald I and Harris, Ronald I and Varvel, Stephen and Varvel, Stephen and Grill, Valdemar E R and Grill, Valdemar E.R and Hakonarson, Hakon and Hakonarson, Hakon and Froguel, Philippe and Froguel, Philippe and Lonsdale, John T and Mauricio, Didac and Lonsdale, John T and Schloot, Nanette C and Mauricio, Didac and Khunti, Kamlesh and Schloot, Nanette C and Greenbaum, Carla J and Khunti, Kamlesh and Asvold, Bjørn Olav and Greenbaum, Carla J and Yderstræde, Knud B and Åsvold, Bjørn Olav and Yderstræde, Knud B and Pearson, Ewan R and Schwartz, Stanley and Pearson, Ewan R and Schwartz, Stanley and Voight, Benjamin F and Voight, Benjamin F and Hansen, Torben and Hansen, Torben and Tuomi, Tiinamaija and Boehm, Bernhard O and Tuomi, Tiinamaija and Boehm, Bernhard O and ... and Bone Mineral Density Childhood and Bone Mineral Density in Childhood Study
Diabetes care, ISSN 0149-5992, 11/2018, Volume 41, Issue 11, pp. 2396 - 2403
OBJECTIVELatent autoimmune diabetes in adults (LADA) shares clinical features with both type 1 and type 2 diabetes; however, there is ongoing debate regarding... 
LADA | VARIANTS | INSULIN-RESISTANCE | FREQUENCY | ENDOCRINOLOGY & METABOLISM | PHENOTYPE | GENETIC ARCHITECTURE | LOCI | INDUCIBLE 6-PHOSPHOFRUCTO-2-KINASE | TYPE-1 | ONSET | Glucose Intolerance - metabolism | Haplotypes | Genome-Wide Association Study | Glucose Intolerance - genetics | Latent Autoimmune Diabetes in Adults - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Immune System Phenomena - genetics | Latent Autoimmune Diabetes in Adults - metabolism | Middle Aged | Diabetes Mellitus, Type 1 - genetics | Diabetes Mellitus, Type 1 - metabolism | Male | Diabetes Mellitus, Type 2 - metabolism | Glucose Intolerance - immunology | Case-Control Studies | Young Adult | Insulin - metabolism | Diabetes Mellitus, Type 2 - immunology | Adult | Female | Aged | Diabetes Mellitus, Type 1 - immunology | Latent Autoimmune Diabetes in Adults - immunology | Genome-wide association studies | Usage | Type 1 diabetes | Analysis | Genetic aspects | Cellular signal transduction | Adults | Health aspects | Diabetes mellitus | Genomes | Diabetes mellitus (insulin dependent) | Insulin | Autophagy | Classification | Glycolysis | Attenuation | Histocompatibility antigen HLA | Research design | Diabetes | Genetic factors | Children | Autoimmune diseases | Population control | Diabetes mellitus (non-insulin dependent) | Phagocytosis | Index Medicus
Journal Article
by Surenan, P and nos, Fotios and Young, Robin and Warren, Helen and Cook, J.P and Manning, Alisa and Grarup, Niels and Sim, Xueling and Barnes, Daniel and Witkowska, Ewa and Staley, James R and Tragante, Vinicius and Tukiainen, Taru and Yaghootkar, Hanieh and Masca, N and Freitag, Christine and Ferreira, Teresa and Giannakopoulou, Olga and Tinker, A and Harakalova, Magdalena and Mihailov, Evelin and Liu, C and Kraja, Aldi and Nielsen, Sune and Rasheed, Asif and Samuel, Maria and Zhao, Wei and Bonnycastle, Lori and Jackson, Anne and Narisu, Narisu and Swift, Amy and Southam, Lorraine and Marten, Jonathan and Huyghe, Jeroen R and Stancáková, Alena and Fava, Cristiano and Ohlsson, T and Matchan, Angela and Stirrups, Kathy and Bork-Jensen, Jette and Gjesing, Anette and Kontto, J and Perola, Markus and Shaw-Hawkins, Sue and Havulinna, Aki and Zhang, H and Donnelly, Louise and Groves, Christopher and Rayner, Nigel William and Neville, Matthew and Robertson, Neil and Yiorkas, A.M and Herzig, K.H and Kajantie, Eero and Zhang, Weihua and Willems, Sara and Lannfelt, Lars and Malerba, Giovanni and Soranzo, Nicole and Trabetti, Elisabetta and Verweij, Niek and Evangelou, Evangelos and Moayyeri, Alireza and Vergnaud, A.-C and Nelson, Christopher P and Poveda, A and Varga, Tibor V and Caslake, Muriel and De Craen, Anton J. M and Trompet, Stella and Luan, Jian'An and Scott, Robert and Harris, Sarah and Liewald, David C and Marioni, Riccardo and Menni, Cristina and Farmaki, Aliki-Eleni and Hallmans, Göran and Renström, Frida and Huffman, Jennifer and Hassinen, M and Burgess, Stephen and Vasan, R.S and Felix, Janine and Uria-Nickelsen, M and Mälarstig, Anders and Reilly, D.F and Hoek, M and Vogt, T.F and Lin, Honghuang and Lieb, Wolfgang and Traylor, Matthew and Markus, Hugh and Highland, Heather and Justice, Anne and Marouli, Eirini and Lindström, Jaana and Uusitupa, Matti and Komulainen, Pirjo and Lakka, Timo and ... and Understanding Soc Sci Grp and Wellcome Trust Case Control Consor and GoT2DGenes Consortium and ExomeBP Consortium and CHD Exome Consortium and Giant Consortiumm and CHARGE Exome Chip Blood Pressure C and EPIC-CVD Consortium and CHARGE Heart Failure Consortiumm and EchoGen Consortiumm and EPIC-InterAct Consortium and Lifelines Cohort Study and Metastroke Consortiumm and T2D-GENES Consortium and Wellcome Trust Case Control Consortium and Understanding Society Scientific Group and EchoGen Consortium and CHD Exome+ Consortium and CHARGE+ Exome Chip Blood Pressure Consortium and CHARGE-Heart Failure Consortium and METASTROKE Consortium and GIANT Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1151 - 1161
Journal Article
by Kraja, Aldi T and Cook, James P and Warren, Helen R and Surenan, Praveen and Liu, Chunyu and Evangelou, Evangelos and Manning, Alisa K and Grarup, Niels and nos, Fotios and Sim, Xueling and Smith, Albert Vernon and Amin, Najaf and Blakemore, Alexana I F and Bork-Jensen, Jette and Brandslund, Ivan and Farmaki, Aliki-Eleni and Fava, Cristiano and Ferreira, Teresa and Herzig, Karl-Heinz and Giri, Ayush and Giulianini, Franco and Grove, Megan L and Guo, Xiuqing and Harris, Sarah E and Have, Christian T and Havulinna, Aki S and Zhang, He and Jørgensen, Marit E and Käräjämäki, AnneMari and Kooperberg, Charles and Linneberg, Allan and Little, Louis and Liu, Yongmei and Bonnycastle, Lori L and Lu, Yingchang and Mägi, Reedik and Mahajan, Anubha and Malerba, Giovanni and Marioni, Riccardo E and Mei, Hao and Menni, Cristina and Morrison, Alanna C and Padmanabhan, Sandosh and Palmas, Walter and Poveda, Alaitz and Rauramaa, Rainer and Rayner, Nigel William and Riaz, Muhammad and Rice, Ken and Richard, Melissa A and Smith, Jennifer A and Southam, Lorraine and Stančáková, Alena and Stirrups, Kathleen E and Tragante, Vinicius and Tuomi, Tiinamaija and Tzoulaki, Ioanna and Varga, Tibor V and Weiss, Stefan and Yiorkas, Anianos M and Young, Robin and Zhang, Weihua and Barnes, Michael R and Cabrera, Claudia P and Gao, He and Boehnke, Michael and Boerwinkle, Eric and Chambers, John C and Connell, John M and Christensen, Cramer K and de Boer, Rudolf A and Deary, Ian J and Dedoussis, George and Deloukas, Panos and Dominiczak, Anna F and Dörr, Marcus and Joehanes, Roby and Edwards, Todd L and Esko, Tõnu and Fornage, Myriam and Franceschini, Nora and Franks, Paul W and Gambaro, Giovanni and Groop, Leif and Hallmans, Göran and Hansen, Torben and Hayward, Caroline and Heikki, Oksa and Ingelsson, Erik and Tuomilehto, Jaakko and Jarvelin, Marjo-Riitta and Kardia, Sharon L R and Karpe, Freik and Kooner, Jaspal S and Lakka, Timo A and Langenberg, Claudia and Lind, Lars and Loos, Ruth J F and Laakso, Markku and McCarthy, Mark I and ... and CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group and Understanding Society Scientific Group and The Understanding Society Scientific Group and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Genetic and Molecular Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Circulation-Cardiovascular Genetics, ISSN 1942-325X, 2017, Volume 10, Issue 5, pp. e001778 - e001778
Journal Article