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by Kohn, M
SYNTHESIS-STUTTGART, ISSN 0039-7881, 11/2012, Volume 44, Issue 21, pp. A118 - A120
Journal Article
Journal Article
Journal of Peptide Science, ISSN 1075-2617, 10/2017, Volume 23, Issue 10, pp. 749 - 756
Journal Article
ChemBioChem, ISSN 1439-4227, 01/2019, Volume 20, Issue 1, pp. 66 - 71
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2015, Volume 43, Issue 1, pp. D531 - D535
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2014, Volume 88, pp. 89 - 100
Computationally supported development of small molecule inhibitors has successfully been applied to protein tyrosine phosphatases in the past, revealing a... 
2-Cyano-2-ene-esters | Phosphatases of regenerating liver | Enzyme inhibitors | Thienopyridone | Virtual screening methods | Dual specificity phosphatases | CHEMISTRY, MEDICINAL | ULTRAFAST SHAPE-RECOGNITION | METASTASIS | PRL-3 PHOSPHATASE | IDENTIFICATION | DISCOVERY | Cell Survival - drug effects | Small Molecule Libraries - pharmacology | Liver Regeneration | Liver - enzymology | Humans | Cells, Cultured | Enzyme Inhibitors - pharmacology | Neoplasms - enzymology | Structure-Activity Relationship | Dose-Response Relationship, Drug | Cell Movement - drug effects | Small Molecule Libraries - chemistry | High-Throughput Screening Assays | Enzyme Inhibitors - chemistry | HEK293 Cells | Cell Proliferation - drug effects | Molecular Docking Simulation | Molecular Structure | Neoplasms - pathology | Phosphoric Monoester Hydrolases - metabolism | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Liver cancer | Phosphatases | Analysis | Liver | Genomics | Nitriles | Methods | PRL, phosphatases of regenerating liver | DIFMUP, 6,8-difluoro-4-methylumbelliferyl phosphate | UPLC-MS, ultra performance liquid chromatography–mass spectrometry | PTP1B, protein tyrosine phosphatase 1B | UFSRAT, ultrafast shape recognition with atom types | VHR, vaccinia H1-related phosphatase | SAR, structure–activity relationship | VS, virtual screening | DSP, dual specificity phosphatase | ROCS, rapid overlay of chemical structures | TCPTP, T-cell protein tyrosine phosphatase | Original | MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide | PTP, protein tyrosine phosphatase | USR, ultrafast shape recognition
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 11/2016, Volume 11, Issue 11, pp. 2944 - 2961
Journal Article
Advances in experimental medicine and biology, ISSN 0065-2598, 2016, Volume 917, p. 209
Phosphatases are involved in basically all cellular processes by dephosphorylating cellular components such as proteins, phospholipids and second messengers.... 
Tumor Suppressor Proteins - metabolism | Animals | Humans | Enzyme Inhibitors - pharmacology | Neoplasms - enzymology | Antineoplastic Agents - pharmacology | Oncogenes | Neoplasms - drug therapy | Phosphoric Monoester Hydrolases - antagonists & inhibitors
Journal Article
Current Opinion in Chemical Biology, ISSN 1367-5931, 06/2013, Volume 17, Issue 3, pp. 361 - 368
Journal Article