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1. Full Text Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
by Dunning, Alison and Michailidou, Kyriaki and Kuchenbaecker, Karoline and Thompson, Deborah and French, Juliet and Beesley, Jonathan and Healey, Sue and Kar, Siddhartha and Pooley, Karen and Lopez-Knowles, Elena and Dicks, Ed and Barrowdale, Daniel and Sinnott-Armstrong, Nicholas A and Sallari, Richard C and Hillman, Kristine and Kaufmann, Susanne and Sivakumaran, Haran and Marjaneh, Mahdi Moradi and Lee, Jason S and Hills, Margaret and Jarosz, Monika and ry, Suzie and Canisius, Sander and KBolla, Manjeet and Dennis, Joe and Wang, Qin and LHopper, John and Southey, Mellissa C and Broeks, Annegien and Schmidt, Marjanka K and Lophatananon, Artitaya and Muir, K and Beckmann, Matthias W and Fasching, Peter and Santos Silva, Isabel and Peto, Julian and Sawyer, Elinor and Tomlinson, Ian and Burwinkel, Barbara and Marme, Federick and Guénel, Pascal and Truong, Thérèse and Bojesen, Stig and Flyger, Henrik and Gonzlez-Neira, Anna and Perez, Jose I.A and Anton-Culver, Hoda and Eunjung, Lee and Arndt, Volker and Brenner, Hermann and Meindl, Alfons and Schmutzler, Rita and Brauch, Hiltrud and Hamann, Ute and Aittomki, Kristiina and Blomqvist, Carl and Ito, Hidemi and Matsuo, Keitaro and Bogdanova, Natalia and Dörk, Thilo and Lindblom, Annika and Margolin, Sara and Kosma, Veli-Matti and Mannermaa, Arto and Tseng, Chiu-Chen and Wu, Anna and Lambrechts, Diether and Wildiers, Hans and Chang-Claude, Jenny and Rudolph, Anja and Peterlongo, Paolo and Radice, Paolo and EOlson, Janet and GGiles, Graham and Milne, Roger L and Haiman, Christopher A and Henderson, Brian and Goldberg, Mark and Teo, Soo Hwang and Yip, Cheng Har and Nord, Silje and Borresen-Dale, Anne-Lise and Kristensen, Vessela and Long, Jirong and Zheng, Wei and Pylks, Katri and Winqvist, Robert and Anulis, Irene and Knight, Julia A and Devilee, Peter and Seynaeve, Caroline and Figueroa, Jonine and Sherman, Mark and Czene, Kamila and Darabi, Hatef and Hollestelle, Antoinette and Ouweland, Ans and Humphreys, Keith and Gao, Yu-Tang and Shu, Xiao-Ou and ... and KConFab Investigators and HEBON and EMBRACE and GEMO Study Collaborators and kConFab Investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 374 - 386
textabstractWe analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor α) in 118,816 subjects from three international... 
BRCA2 MUTATION CARRIERS | MAMMOGRAPHIC DENSITY | WOMEN | METAANALYSIS | BONE-MINERAL DENSITY | MODIFIERS | DISEASE | GENETICS & HEREDITY | SUSCEPTIBILITY LOCUS | GENOME-WIDE ASSOCIATION | REVEALS | Gene Expression | Genetic Predisposition to Disease | Genetic Association Studies | Humans | Risk Factors | Cell Cycle Proteins - metabolism | Gene Expression Regulation, Neoplastic | Chromosomes, Human, Pair 6 - genetics | Breast Neoplasms - metabolism | Carrier Proteins - genetics | Phenotype | Breast Neoplasms - genetics | Carrier Proteins - metabolism | Estrogen Receptor alpha - genetics | Base Sequence | Cell Cycle Proteins - genetics | Protein Binding | Estrogen Receptor alpha - metabolism | Female | Polymorphism, Single Nucleotide | Genetic variation | Breast cancer | Genetic aspects | Gene expression | Properties | Health aspects | Identification and classification | Risk factors | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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2. Full Text Five endometrial cancer risk loci identified through genome-wide association analysis
by Cheng, Timothy H.T and Thompson, Deborah J and O'Mara, Tracy A and Painter, Jodie N and Glubb, Dylan M and Flach, Susanne and Lewis, Annabelle and French, Juliet D and Freeman-Mills, Luke and Church, David and Gorman, Maggie and Martin, Lynn and Hodgson, Shirley and MWebb, Penelope and Attia, John and Holliday, Elizabeth G and McEvoy, Mark and Scott, Rodney J and KHenders, Anjali and Martin, Nicholas G and Montgomery, Grant W and Nyholt, Dale R and Ahmed, Shahana and Healey, Catherine S and Shah, Mitul and Dennis, Joe and Fasching, Peter A and Beckmann, Matthias W and Hein, Alexander and Ekici, Arif B and Hall, Per and Czene, Kamila and Darabi, Hatef and Li, Jingmei and Dörk, Thilo and Dürst, Matthias and Hillemanns, Peter and Runnebaum, Ingo and Amant, Frederic and Schrauwen, Stefanie and Zhao, Hui and Lambrechts, Diether and Depreeuw, Jeroen and Dowdy, Sean C and Goode, Ellen L and Fridley, Brooke L and Winham, Stacey J and NjØlstad, Tormund S and Salvesen, Helga B and Trovik, Jone and Werner, Henrica M.J and Ashton, Katie and Otton, Geoffrey and Proietto, Tony and Liu, Tao and Mints, Miriam and Tham, Emma and Li, Mulin Jun and Yip, Shun H and Wang, Junwen and KBolla, Manjeet and Michailidou, Kyriaki and Wang, Qin and Tyrer, Jonathan P and Dunlop, Malcolm and Houlston, Richard and Palles, Claire and Hopper, John L and Peto, Julian and Swerdlow, Anthony J and Burwinkel, Barbara and Brenner, Hermann and Meindl, Alfons and Brauch, Hiltrud and Lindblom, Annika and Chang-Claude, Jenny and Couch, Fergus J and Giles, Graham G and Kristensen, Vessela N and Cox, Angela and MCunningham, Julie and Pharoah, Paul D.P and Dunning, Alison M and Edwards, Stacey L and Easton, Douglas F and Tomlinson, Ian and Spurdle, Amanda B and RENDOCAS and RENDOCAS CHIBCHA Consortium and AOCS Group and Australian Natl Endometrial Canc S and Natl Study Endometrial Canc Geneti and Australian National Endometrial Cancer Study Group (ANECS) and National Study of Endometrial Cancer Genetics Group (NSECG) and CHIBCHA Consortium and The Australian National Endometrial Cancer Study Group (ANECS)
Nature Genetics, ISSN 1061-4036, 06/2016, Volume 48, Issue 6, pp. 667 - 674
We conducted a meta-analysis of three endometrial cancer genome-wide association studies (GWAS) and two follow-up phases totaling 7,737 endometrial cancer... 
COHORT PROFILE | HETEROGENEITY | 8Q24 | METAANALYSIS | REPLICATION | VARIANTS | COLORECTAL-CANCER | TRANSCRIPTION | GENETICS & HEREDITY | SUSCEPTIBILITY LOCI | SCAN | Promoter Regions, Genetic | Genetic Predisposition to Disease | Genome-Wide Association Study | Endometrial Neoplasms - genetics | Humans | Female | Chromosomes, Human, Pair 8 | Polymorphism, Single Nucleotide | Genome-wide association studies | Research | Endometrial cancer | Gene expression | Analysis | Risk factors | Medical research | Biomedical research | Funding | Genomes | Epidemiology | Ovarian cancer | Proteins | Studies | Confidence intervals | Hormone replacement therapy | Reproductive system | Health risk assessment
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