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Pharmacology Research & Perspectives, ISSN 2052-1707, 06/2015, Volume 3, Issue 3, pp. e00148 - n/a
There has been intensive effort to identify in vivo biomarkers that can be used to monitor drug‐induced kidney damage and identify injury before significant... 
NGAL | kidney | Biomarker | M‐CSF | nephrotoxicity | KIM‐1 | KIM-1 | M-CSF | Proteins | Biomarkers | Cytotoxicity | Kidneys | Rodents | Original
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2017, Volume 49, Issue 7, pp. 1025 - 1034
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, p. 35
The complement cascade is a highly sophisticated network of proteins that are well regulated and directed in response to invading pathogens or tissue injury... 
Protein binding
Journal Article
Cytokine, ISSN 1043-4666, 11/2014, Volume 70, Issue 1, pp. 35 - 35
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2015, Volume 101, pp. 96 - 102
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 08/2014, Volume 92, Issue 7, p. 631
  The complement system is a major component of our innate immune system, in which the complement proteins C5a and C5a-des Arg bind to two G-protein-coupled... 
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 12/2016, Volume 7, Issue 12, pp. 1034 - 1038
MCC950 is an orally bioavailable small molecule inhibitor of the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome that exhibits... 
NLRP3 | microsome | MCC950 | metabolite | cytochrome P450 | inflammasome
Journal Article
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