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2010, Progress in molecular biology and translational science, ISBN 0123852331, Volume 97., xii, 286
Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive... 
Alimentary canal | Medicine: General Issues | Digestive organs
Book
Developmental Cell, ISSN 1534-5807, 2009, Volume 16, Issue 4, pp. 588 - 599
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 5, pp. S-519 - S-519
Journal Article
Cell Metabolism, ISSN 1550-4131, 11/2018, Volume 28, Issue 5, p. 787
Recent reports identified activation of the GABA signaling pathway as a means to induce transdifferentiation of pancreatic [alpha] cells into [beta] cells.... 
Pancreatic beta cells | Glucagon | GABA | Glucose | Dextrose
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2014, Volume 20, Issue 6, pp. 932 - 933
The discovery of a potent mitogen for insulin-producing pancreatic β cells, optimistically termed “betatrophin,” excited researchers and laypeople alike,... 
MICE | BETA-CELL REPLICATION | ANGPTL8/BETATROPHIN | ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Male | Angiopoietins - metabolism | Insulin-Secreting Cells - cytology | Animals | Pancreatic beta cells | Index Medicus
Journal Article
Cell Stem Cell, ISSN 1934-5909, 04/2015, Volume 16, Issue 4, pp. 343 - 344
While studies of organ development have traditionally relied on model organisms, recent advances in embryonic stem cell (ESC) culture allow investigation of... 
TRANSCRIPTION FACTORS | CELL | FOXA2 | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Pancreas - physiology | Enhancer Elements, Genetic - genetics | Endoderm - physiology | Humans | Embryonic Stem Cells - physiology | Gastrula - physiology | Index Medicus
Journal Article
Hepatology, ISSN 0270-9139, 02/2010, Volume 51, Issue 2, p. 376
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1998 - 2006
Journal Article
Circulation Research, ISSN 0009-7330, 06/2008, Volume 102, Issue 12, pp. 1548 - 1557
Journal Article
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, pp. 11756 - 11756
Human pancreatic islets of Langerhans contain five distinct endocrine cell types, each producing a characteristic hormone. The dysfunction or loss of the... 
HETEROGENEITY | DIFFERENTIAL EXPRESSION | GLUCOSE | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | PERSPECTIVES | MECHANISMS | NUCLEOTIDE-GATED CHANNELS | IDENTIFICATION | FAILURE | RESOURCE | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 6, pp. 2052 - 2062
Background & Aims The winged helix transcription factors Foxa1 and Foxa2 are expressed in all epithelia of the gastrointestinal tract from its embryonic origin... 
Gastroenterology and Hepatology | RESPONSE ELEMENT | GLUCOSE-HOMEOSTASIS | GLUCAGON-LIKE PEPTIDE-1 | PROGLUCAGON GENE-TRANSCRIPTION | IN-VIVO | INSULIN-SECRETION | PANCREATIC BETA-CELLS | GASTROENTEROLOGY & HEPATOLOGY | ISLET CELLS | EXPRESSION | ENDOCRINE-CELLS | Immunohistochemistry | Hepatocyte Nuclear Factor 3-beta - genetics | Intestine, Small - pathology | Peptide YY - metabolism | Homeodomain Proteins - metabolism | Male | RNA, Messenger - metabolism | Cell Differentiation | Enteroendocrine Cells - metabolism | Proglucagon - metabolism | Somatostatin - metabolism | Repressor Proteins - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Mucin-2 - metabolism | Enteroendocrine Cells - pathology | Somatostatin-Secreting Cells - pathology | Glucagon-Like Peptide 1 - metabolism | Glucagon-Like Peptide 2 - metabolism | Hepatocyte Nuclear Factor 3-alpha - deficiency | Hepatocyte Nuclear Factor 3-alpha - genetics | PAX6 Transcription Factor | Goblet Cells - metabolism | Hepatocyte Nuclear Factor 3-alpha - metabolism | Mice, Knockout | Mucin-5B - metabolism | Animals | Eye Proteins - metabolism | Mucin 5AC - metabolism | LIM-Homeodomain Proteins | Mice | Transcription Factors | Goblet Cells - pathology | Intestine, Small - metabolism | Somatostatin-Secreting Cells - metabolism | Hepatocyte Nuclear Factor 3-beta - deficiency | Paired Box Transcription Factors - metabolism | Chromatin | Messenger RNA | DNA binding proteins | Cholecystokinin | Peptides | Mucins | Index Medicus | Abridged Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2017, Volume 26, Issue 6, pp. 809 - 811
The underlying mechanisms and functional significance of pancreatic β cell heterogeneity are an intensive area of investigation. In a recent paper, performed... 
HETEROGENEITY | BETA-CELLS | ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Sequence Analysis, RNA | Mutation | Insulin-Secreting Cells | Pancreas | Single-Cell Analysis | Humans
Journal Article
Diabetes Research and Clinical Practice, ISSN 0168-8227, 01/2017, Volume 123, p. 24
Type 2 diabetes is a highly heritable disease, but only [approximately equal to]15% of this heritability can be explained by known genetic variant loci. In... 
Type 2 diabetes | Epigenetic inheritance | Pancreatic beta cells | Disease susceptibility | Gene expression | Genomics | Medical colleges | Exercise | Genes | Physiological aspects
Journal Article
Journal Article