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Beilstein Journal of Organic Chemistry, ISSN 1860-5397, 11/2016, Volume 12, Issue 1, pp. 2523 - 2534
Starting from racemic naringenin ((+/-)-1), a mixture of dracocephin A stereoisomers 6-(2 ''-pyrrolidinone-5 ''-yl) naringenin (+/-)-2a-d and its regioisomer,... 
Dracocephalum rupestre | Flavonoid alkaloids | ECD calculation | HPLC-ECD | Absolute configuration | Dracocephins A-B | dracocephins A-B | CIRCULAR-DICHROISM | ABSOLUTE-CONFIGURATION | CHEMISTRY, ORGANIC | absolute configuration | flavonoid alkaloids | P-GLYCOPROTEIN | dracocephins A–B | HPLC–ECD
Journal Article
Molecules (Basel, Switzerland), 05/2012, Volume 17, Issue 5, p. 5893
The synthetic investigation of biologically active natural compounds serves two main purposes: (i) the total synthesis of alkaloids and their analogues; (ii)... 
Vincristine - analogs & derivatives | Vinblastine - chemistry | Vinblastine - analogs & derivatives | Antineoplastic Agents - chemistry | Oxidative Coupling | Vincristine - chemistry
Journal Article
Current Organic Chemistry, ISSN 1385-2728, 08/2014, Volume 18, Issue 15, pp. 2037 - 2042
The carbon-carbon double bond offers a possibility to incorporate a cyclopropane ring into a molecule. The special electronic nature of the cyclopropane ring... 
Cyclopropanation | Cyclopropane ring | Natural compounds | Biological activity | natural compounds | BUXUS-HYRCANA | NUCLEOSIDE ANALOGS | ACIDS | ERGOT ALKALOIDS | CHEMISTRY, ORGANIC | cyclopropane ring | cyclopropanation | BIOSYNTHESIS | BONDS | TRITERPENOID ALKALOIDS | DERIVATIVES
Journal Article
Periodica Polytechnica Chemical Engineering, ISSN 0324-5853, 2015, Volume 59, Issue 1, pp. 3 - 15
Journal Article
Tetrahedron, ISSN 0040-4020, 12/2015, Volume 71, Issue 51, pp. 9579 - 9586
Bannucine is an isolated from the dried leaves of . The molecule is a derivative of vindoline bearing a C10 substituent, a pattern common to the antineoplastic... 
Aspidosperma alkaloids | N-acylaminocarbinol | Bannucine | Iminium chemistry | Alkaloid synthesis | VINCA ALKALOIDS | VINDOLINE | ANALOGS | INTERMOLECULAR ADDITION-REACTIONS | ABSOLUTE-STRUCTURE | CHEMISTRY, ORGANIC | VINBLASTINE | N-ACYLIMINIUM IONS | CYCLIZATIONS | RING | TUMOR-CELL-LINES
Journal Article
Heterocycles, ISSN 0385-5414, 2015, Volume 90, Issue 1, pp. 316 - 326
Vinorelbine condensed with a cyclopropane ring in the position 14 and 15 of the vindoline monomer part was synthesized and was found to have excellent... 
CELL LUNG-CANCER | VINBLASTINE-TYPE ALKALOIDS | 5 '-Desmethylene-cyclopropano-vinblastine | FEASIBILITY | Different Tumor Cell Line | ANALOGS | Antitumor Activity | VINCRISTINE | CHEMISTRY, ORGANIC | N-1-Formyl-cyclopropano-vinorelbine | LINES
Journal Article
Heterocycles, ISSN 0385-5414, 2014, Volume 89, Issue 3, pp. 653 - 668
A new type of vinblastine and vincristine derivatives was synthesized. The carbon carbon double bond in position 14 and 15 of the vindoline ring was... 
FEASIBILITY | CATHARANTHUS-ROSEUS | VINDOLINE | NATURAL-PRODUCTS | CHEMISTRY, ORGANIC | VINBLASTINE | DERIVATIVES | LINES | DON,G. CELL-CULTURES
Journal Article
Heterocycles, ISSN 0385-5414, 2013, Volume 87, Issue 11, pp. 2299 - 2317
10-Bromovindoline and its 14,15-dihydro- and 14,15-cyclopropano derivatives were coupled in the position 16 with (L)- and (D)-tryptophan methyl esters. The... 
CHEMISTRY, ORGANIC | VINBLASTINE | ALKALOIDS
Journal Article
Heterocycles, ISSN 0385-5414, 2012, Volume 84, Issue 2, pp. 1171 - 1178
In the course of the reaction between galanthamine and diazomethane in the presence of a catalyst, such as palladium(II) acetate or copper(I) bromide,... 
ORGANIC-SYNTHESIS | ASYMMETRIC-SYNTHESIS | (-)-GALANTHAMINE | REAGENTS | ANALOGS | CHEMISTRY, ORGANIC | Methylene Insertion | Galanthamine | TRIMETHYLSILYLDIAZOMETHANE | Cyclopropanation | ACETYLCHOLINESTERASE | Cycloheptatriene Ring | GALANTAMINE | (+/-)-GALANTHAMINE | Diazomethane | ALKALOIDS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2010, Volume 51, Issue 52, pp. 6932 - 6934
New cyclopentanoisoquinolinones were formed via rearrangement of spiro-substituted benzazepinones. Attempted cyclisation of N-methylated spiro... 
Amaryllidaceae alkaloids | Cyclopentanoisoquinolinone | Spirocyclohexenone | Rearrangement | (-)-GALANTHAMINE | ALZHEIMERS-DISEASE | CHEMISTRY, ORGANIC | GALANTAMINE | Tetrahedrons | Alkaloids | Derivatives | Methylation
Journal Article
International Journal of Organic Chemistry, ISSN 2161-4687, 2014, Volume 4, Issue 5, pp. 309 - 313
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 10/2002, Volume 67, Issue 21, pp. 7255 - 7260
The first syntheses of the alkaloids (−)-mehranine (3), (+)-voaphylline/conoflorine (4), (+)-N a-methylvoaphylline/hecubine (5), and (−)-lochnericine (2) were... 
Journal Article
Heterocycles, ISSN 0385-5414, 02/2011, Volume 83, Issue 3, pp. 581 - 589
Demethoxy-lycoraminone (8) was prepared in several steps starting from the appropriate benzo[c]azepine dione derivative (9). Ketone (9) was protected as a... 
Demethoxy Derivative | Amarllidaceee Alkaloid | ALZHEIMERS-DISEASE | GALANTHAMINE-TYPE ALKALOIDS | CHEMISTRY, ORGANIC | Spirobenzazepine | GALANTAMINE | Lycoramine | ACETYLCHOLINESTERASE INHIBITORS | Galanthamine | SKELETON
Journal Article
Heterocycles, ISSN 0385-5414, 07/2007, Volume 71, Issue 7, pp. 1553 - 1563
Aromatic electrophilic substitution reactions of the monomer alkaloid vindoline resulted in new derivatives substituted on ring A. Halogene-, nitro-, amino-... 
Nitration | Bisindole Alkaloid | Vindoline | Aromatic Electrophilic Substitution | Halogenation | REARRANGEMENT | VINCA ALKALOIDS | INDOLE | nitration | VINCRISTINE | CHEMISTRY, ORGANIC | VINBLASTINE | halogenation | bisindole alkaloid | aromatic electrophilic substitution | vindoline | DIHYDROINDOLE ALKALOIDS
Journal Article
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