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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2192 - 16
The transcription factor Yin Yang 1 (YY1) plays an important role in human disease. It is often overexpressed in cancers and mutations can lead to a congenital... 
YY1 | REGULATOR | STEM-CELLS | MULTIDISCIPLINARY SCIENCES | MOUSE | CELL-CYCLE | MICE | PROLIFERATION | NEURAL CREST | PROTEIN-SYNTHESIS | P53 | Cell proliferation | Brain | Cerebral cortex | Cell survival | Cortex | Protein biosynthesis | YY1 protein | Progenitor cells | Haploinsufficiency | Proteins | Neurological diseases | Developmental stages | Protein synthesis | Cells (biology) | Dependence | Neural stem cells | Metabolic pathways | Mutation
Journal Article
Journal Article
Journal Article
Cell Stem Cell, ISSN 1934-5909, 04/2019, Volume 24, Issue 4, pp. 637 - 653.e9
Increasing evidence suggests that cancer cells highjack developmental programs for disease initiation and progression. Melanoma arises from melanocytes that... 
YY1 | development | neural crest | melanoma | protein synthesis | metabolism | tumor initiation | STEM-CELLS | METASTASIS | INITIATION | MYC | PGC1-ALPHA | RESISTANCE | SUPPRESSION | TRANSCRIPTION FACTOR | EXPRESSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Journal Article
PLoS Biology, ISSN 1544-9173, 05/2013, Volume 11, Issue 5
  Wnt Planar Cell Polarity (PCP) signaling is a universal regulator of polarity in epithelial cells, but it regulates axon outgrowth in neurons, suggesting the... 
Proteins | Studies | Phosphorylation | Brain research | Insects | Neurons | Cloning | Grants | Kinases | Alzheimers disease | Mammals | Experiments
Journal Article
PLoS Genetics, ISSN 1553-7390, 12/2013, Volume 9, Issue 12
  RNA-seq is a promising technology to re-sequence protein coding genes for the identification of single nucleotide variants (SNV), while simultaneously... 
Proteins | Transcription factors | Genomics | Genomes | Mutation | Grants | Kinases | Gene expression | Generalized linear models | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6683
Transcriptional reprogramming of proliferative melanoma cells into a phenotypically distinct invasive cell subpopulation is a critical event at the origin of... 
TRANSCRIPTION FACTOR-BINDING | ENCYCLOPEDIA | R/BIOCONDUCTOR PACKAGE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | PHENOTYPE | ENHANCER | MITF | DIFFERENTIATION | CHROMOSOME CONFORMATION CAPTURE | TAZ | Chromatin - metabolism | RNA, Small Interfering - genetics | Transcription Factor AP-1 - genetics | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Gene Regulatory Networks | Transcription Factor AP-1 - metabolism | DNA-Binding Proteins - metabolism | DNA Methylation | Protein Isoforms - metabolism | Cell Transformation, Neoplastic - genetics | Melanoma - genetics | Transcription, Genetic | Antineoplastic Agents - pharmacology | Nuclear Proteins - genetics | Cellular Reprogramming - genetics | Chromatin - chemistry | Melanoma - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Microphthalmia-Associated Transcription Factor - metabolism | Signal Transduction | Neoplasm Invasiveness | SOXE Transcription Factors - metabolism | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Melanoma - pathology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Cell Transformation, Neoplastic - metabolism | Transcription Factors - metabolism | Histones - genetics | Melanoma - drug therapy | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Histones - metabolism | Cell Transformation, Neoplastic - pathology | Microphthalmia-Associated Transcription Factor - genetics | Protein Isoforms - genetics | RNA, Small Interfering - metabolism | SOXE Transcription Factors - genetics
Journal Article
PLoS Genetics, ISSN 1553-7390, 2013, Volume 9, Issue 12, p. e1003997
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2013, Volume 45, Issue 2, pp. 186 - 190
Journal Article