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1. Full Text P-192 Unraveling the Functional Role of Dysbiosis in Crohnʼs Disease
by Kamada, Nobuhiko
Inflammatory Bowel Diseases, ISSN 1078-0998, 03/2016, Volume 22, p. S67
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2. Full Text 262 – Dietary Serine Regulate the Integrity of Intestinal Mucus Barrier During Intestinal Inflammation
by Sugihara, Kohei and Kamada, Nobuhiko
Gastroenterology, ISSN 0016-5085, 05/2019, Volume 156, Issue 6, pp. S-50 - S-50
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3. Full Text Print and Digital Media Review
by Kamada, Nobuhiko
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1827 - 1827
Gastroenterology and Hepatology
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4. Full Text P144 IMPAIRED IL-22 PRODUCTION BY RORγT+GROUP 3 INNATE LYMPHOID CELLS IN CROHN’S DISEASE
by Hayashi, Atsushi and Kamada, Nobuhiko
Gastroenterology, ISSN 0016-5085, 02/2019, Volume 156, Issue 3, pp. S96 - S96
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5. Full Text Sa1751 Monocyte-Derived Intestinal Macrophages Control Enteric Pathogen Eradication via Eliciting Innate and Adaptive Lymphocyte Responses
by Kamada, Nobuhiko
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 5, pp. S-288 - S-288
Gastroenterology and Hepatology
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6. Full Text P-195 Intestinal Macrophages Elicit IL-1β Mediated Innate Lymphoid Cells Activation During Colitis
by Nobuhiko, Kamada
Inflammatory Bowel Diseases, ISSN 1078-0998, 12/2014, Volume 20, p. S104
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7. Full Text P144 IMPAIRED IL-22 PRODUCTION BY RORγT+GROUP 3 INNATE LYMPHOID CELLS IN CROHN’S DISEASE
by Hayashi, Atsushi and Kamada, Nobuhiko
Inflammatory Bowel Diseases, ISSN 1078-0998, 02/2019, Volume 25, Issue Supplement_1, pp. S66 - S66
Abstract Background Interleukin (IL)-22 plays a prominent role in the regulation of epithelial barrier integrity and the promotion of tissue repair.... 
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8. Full Text Role of the gut microbiota in immunity and inflammatory disease
by Kamada, Nobuhiko and Seo, Sang-Uk and Chen, Grace Y and Núñez, Gabriel
Nature Reviews Immunology, ISSN 1474-1733, 05/2013, Volume 13, Issue 5, pp. 321 - 335
The mammalian intestine is colonized by trillions of microorganisms, most of which are bacteria that have co-evolved with the host in a symbiotic relationship.... 
INTESTINAL INFLAMMATION | SYMBIOTIC BACTERIA | ESCHERICHIA-COLI O157-H7 | COMMENSAL BACTERIA | CROHNS-DISEASE | TOLL-LIKE RECEPTORS | REGULATORY T-CELLS | LECTIN REGIII-GAMMA | INNATE LYMPHOID-CELLS | IMMUNOLOGY | SEGMENTED FILAMENTOUS BACTERIA | Gastrointestinal Tract - immunology | Inflammation - microbiology | Animals | Intestinal Mucosa - immunology | Humans | Symbiosis - immunology | Gastrointestinal Tract - microbiology | Inflammation - immunology | Intestinal Mucosa - microbiology | Metagenome - immunology | Host-Pathogen Interactions - immunology | Physiological aspects | Inflammation | Genetic aspects | Immune response | Research | Microbiota (Symbiotic organisms)
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9. Full Text Control of pathogens and pathobionts by the gut microbiota
by Kamada, Nobuhiko and Chen, Grace Y and Inohara, Naohiro and Núñez, Gabriel
Nature Immunology, ISSN 1529-2908, 07/2013, Volume 14, Issue 7, pp. 685 - 690
A dense resident microbial community in the gut, referred as the commensal microbiota, coevolved with the host and is essential for many host physiological... 
CLOSTRIDIUM-DIFFICILE INFECTION | ESCHERICHIA-COLI STRAINS | GENOME SEQUENCE | INTESTINAL MICROBIOTA | MAINTAIN HOMEOSTASIS | NITRIC-OXIDE | INNATE | HOST | HYDROGEN-SULFIDE | IMMUNOLOGY | ORGANIC-ACIDS | Host-Pathogen Interactions | Gastrointestinal Tract - immunology | Animals | Bacterial Infections - immunology | Humans | Gastrointestinal Tract - microbiology | Metagenome - immunology | Bacterial Infections - microbiology | Gastrointestinal Tract - metabolism | Physiological aspects | Commensalism | Control | Pathogenic microorganisms | Research | Microbiota (Symbiotic organisms)
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10. Full Text Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota
by Nobuhiko Kamada and Yun-Gi Kim and Ho Pan Sham and Bruce A. Vallance and José L. Puente and Eric C. Martens and Gabriel Núñez
Science, ISSN 0036-8075, 6/2012, Volume 336, Issue 6086, pp. 1325 - 1329
The virulence mechanisms that allow pathogens to colonize the intestine remain unclear. Here, we show that germ-free animals are unable to eradicate... 
Pathogens | Microbiota | Commensals | Diet | Virulence | REPORTS | Bacteria | Mice | Infections | Feces | Bacterial colonization | CELLS | ENTEROCYTE EFFACEMENT | EFFACING PATHOGEN | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | LER | INFECTION | MICE | MODEL | CITROBACTER-RODENTIUM | LOCUS | Citrobacter rodentium - immunology | Specific Pathogen-Free Organisms | Virulence Factors - genetics | Citrobacter rodentium - genetics | Enterobacteriaceae Infections - microbiology | Mice, Inbred C57BL | Bacterial Proteins - genetics | Bacterial Load | Bacteroides - growth & development | Citrobacter rodentium - pathogenicity | Intestinal Mucosa - microbiology | Enterobacteriaceae Infections - immunology | Citrobacter rodentium - growth & development | Feces - microbiology | Animals | Intestines - microbiology | Germ-Free Life | Bacterial Proteins - metabolism | Virulence Factors - metabolism | Escherichia coli - growth & development | Gene Expression Regulation, Bacterial | Metagenome | Microbial Interactions | Physiological aspects | Genetic aspects | Virulence (Microbiology) | Microbiota (Symbiotic organisms) | Gene expression | Immune systems | Escherichia coli | Citrobacter | Strain
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11. Full Text Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state T H17 cells in the intestine
by Shaw, Michael H and Kamada, Nobuhiko and Kim, Yun-Gi and Núñez, Gabriel
Journal of Experimental Medicine, ISSN 0022-1007, 02/2012, Volume 209, Issue 2, pp. 251 - 258
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12. Full Text P011 ADHERENT-INVASIVE ESCHERICHIA COLI UTILIZES SERINE CATABOLISM TO OUTCOMPETE ITS COMMENSAL COMPETITORS
by Kitamoto, Hiroko and Kitamoto, Sho and Kamada, Nobuhiko
Gastroenterology, ISSN 0016-5085, 01/2018, Volume 154, Issue 1, pp. S7 - S7
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13. Full Text P028 DYSBIOSIS DRIVEN LUMINAL MALMETABOLISM INCREASES THE RISK OF C. DIFFICLILE INFECTION IN PATIENTS WITH ULCERATIVE COLITIS
by Nagao-Kitamoto, Hiroko and Kitamoto, Sho and Kamada, Nobuhiko
Gastroenterology, ISSN 0016-5085, 01/2018, Volume 154, Issue 1, pp. S15 - S15
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14. Full Text Regulation of the Immune System by the Resident Intestinal Bacteria
by Kamada, Nobuhiko and Núñez, Gabriel
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 6, pp. 1477 - 1488
The microbiota is an important factor in the development of the immune response. The interaction between the gastrointestinal tract and resident microbiota is... 
Gastroenterology and Hepatology | Microbiota | IgA | Innate Lymphoid Cells | Regulatory T Cell | Th17 | ROR-GAMMA-T | DENDRITIC CELLS | COMMENSAL BACTERIA | RETINOIC-ACID | GERM-FREE MICE | INNATE LYMPHOID-CELLS | GUT MICROBIOTA | SEGMENTED FILAMENTOUS BACTERIA | ARYL-HYDROCARBON RECEPTOR | CHAIN FATTY-ACIDS | GASTROENTEROLOGY & HEPATOLOGY | Immune System - microbiology | Humans | Lymphocytes - microbiology | Intestines - immunology | Lymphoid Tissue - immunology | Host-Pathogen Interactions | Bacteria - immunology | Animals | Intestines - microbiology | Lymphocytes - immunology | Bacteria - classification | Immune System - immunology | Lymphoid Tissue - microbiology | Bacteria | Laws, regulations and rules | Immunotherapy | Gastrointestinal system | Immune system | regulatory T cell | innate lymphoid cells
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15. Full Text P011 ADHERENT-INVASIVE ESCHERICHIA COLI UTILIZES SERINE CATABOLISM TO OUTCOMPETE ITS COMMENSAL COMPETITORS
by Kitamoto, Sho and Kitamoto, Hiroko and Kamada, Nobuhiko
Inflammatory Bowel Diseases, ISSN 1078-0998, 01/2018, Volume 24, Issue suppl_1, pp. S5 - S5
Abstract Background Crohn's disease (CD) patients are often colonized by adherent-invasive Escherichia coli (AIEC). Although the colonization by AIEC is known... 
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16. Full Text P028 DYSBIOSIS DRIVEN LUMINAL MALMETABOLISM INCREASES THE RISK OF C. DIFFICLILE INFECTION IN PATIENTS WITH ULCERATIVE COLITIS
by Nagao-Kitamoto, Hiroko and Kitamoto, Sho and Kamada, Nobuhiko
Inflammatory Bowel Diseases, ISSN 1078-0998, 01/2018, Volume 24, Issue suppl_1, pp. S11 - S11
Abstract Backgrounds Clostridium difficile infection (CDI) is recognized as a major clinical complication in patients with ulcerative colitis (UC). However,... 
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17. Full Text A complex microworld in the gut: Harnessing pathogen-commensal relations
by Kamada, Nobuhiko and Chen, Grace and Núñez, Gabriel
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1190 - 1191
  Human infection by diarrheagenic Escherichia coli strains cause substantial morbidity and mortality worldwide each year. Unfortunately, effective therapies... 
Host-Pathogen Interactions | Intestines - microbiology | Humans | Bacteria - virology | Pathogens | Bacterial infections | E coli | Digestive system | Bacteriology
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18. Full Text The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
by Kim, Yun-Gi and Kamada, Nobuhiko and Shaw, Michael H and Warner, Neil and Chen, Grace Y and Franchi, Luigi and Núñez, Gabriel
Immunity, ISSN 1074-7613, 2011, Volume 34, Issue 5, pp. 769 - 780
The intracellular sensor Nod2 is activated in response to bacteria, and the impairment of this response is linked to Crohn's disease. However, the function of... 
DENDRITIC CELLS | CROHNS-DISEASE | INNATE IMMUNE-RESPONSES | EFFACING PATHOGEN | MACROPHAGES | HOST-DEFENSE | TOXOPLASMA-GONDII | CITROBACTER-RODENTIUM INFECTION | MUCOSAL INFECTION | IMMUNOLOGY | T-CELLS | Nod2 Signaling Adaptor Protein - deficiency | Citrobacter rodentium - immunology | Chemokine CCL2 - immunology | Mice, Inbred C57BL | Nod2 Signaling Adaptor Protein - biosynthesis | Nod2 Signaling Adaptor Protein - immunology | Colitis - pathology | Stromal Cells - immunology | Monocytes - immunology | Mice, Knockout | Enterobacteriaceae Infections - immunology | Animals | Colitis - microbiology | Mice | Colitis - immunology | Disease Models, Animal | Medical colleges | Crohn's disease | Sensors | Analysis | Bacterial infections | Colleges & universities | Gram-positive bacteria | Infections | Kinases | Small intestine | Recruitment | Inflammatory bowel disease | Rodents | Bacteria | Chemokines | Immune system | Cancer
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19. Full Text Interleukin-22 Regulates the Complement System to Promote Resistance against Pathobionts after Pathogen-Induced Intestinal Damage
by Hasegawa, Mizuho and Yada, Shoko and Liu, Meng Zhen and Kamada, Nobuhiko and Muñoz-Planillo, Raúl and Do, Nhu and Núñez, Gabriel and Inohara, Naohiro
Immunity, ISSN 1074-7613, 10/2014, Volume 41, Issue 4, pp. 620 - 632
Pathobionts play a critical role in disease development, but the immune mechanisms against pathobionts remain poorly understood. Here, we report a critical... 
CLOSTRIDIUM-DIFFICILE INFECTION | IMMUNITY | TOXIN-B | FECAL MICROBIOTA TRANSPLANTATION | COMMENSAL BACTERIA | PROTECTIVE ROLE | DISEASE | HOST-DEFENSE | GUT MICROBIOTA | IMMUNOLOGY | IL-22 | Microbiota - immunology | Clostridium difficile - immunology | Mice, Inbred C57BL | Intestines - injuries | Phagocytosis - immunology | Elapid Venoms - pharmacology | Complement C3 - immunology | Mice, Knockout | Interleukins - genetics | Animals | Enterocolitis, Pseudomembranous - mortality | Intestines - microbiology | Enterocolitis, Pseudomembranous - immunology | Interleukins - immunology | Complement C3 - biosynthesis | Mice | Enterobacteriaceae - growth & development | Interleukins | Drug resistance in microorganisms | Development and progression | Inflammatory bowel disease | Statistical analysis | Antibiotics | Mortality | Rodents | Colleges & universities | Diarrhea | Homeostasis | Bacteria | Infections
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20. Full Text The Role of Dietary Nutrients in Inflammatory Bowel Disease
by Sugihara, Kohei and Morhardt, Tina L and Kamada, Nobuhiko
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, p. 3183
Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disease of the gastrointestinal tract. Although the precise etiology of IBD remains... 
microbiota | diet | immunity | inflammatory bowel disease (IBD) | intestinal barrier | CROHNS-DISEASE | NITRIC-OXIDE SYNTHASE | ULCERATIVE-COLITIS | INDOLEAMINE 2,3-DIOXYGENASE | GUT MICROBIOTA | IMMUNOLOGY | AMINO-ACID | ARYL-HYDROCARBON RECEPTOR | CHAIN FATTY-ACIDS | DSS-INDUCED COLITIS | NF-KAPPA-B | Medical nutrition therapy | Inflammatory bowel diseases | Usage | Diet therapy
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