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by Estrada, Karol and Styrkarsdottir, Unnur and Evangelou, Evangelos and Hsu, Yi-Hsiang and Duncan, Emma L and Ntzani, Evangelia E and Oei, Ling and Albagha, Omar M E and Amin, Najaf and Kemp, John P and Koller, Daniel L and Li, Guo and Liu, Ching-Ti and Minster, Ryan L and Moayyeri, Alireza and Vandenput, Liesbeth and Willner, Dana and Xiao, Su-Mei and Yerges-Armstrong, Laura M and Zheng, Hou-Feng and Alonso, Nerea and Eriksson, Joel and Kammerer, Candace M and Kaptoge, Stephen K and Leo, Paul J and Thorleifsson, Gudmar and Wilson, Scott G and Wilson, James F and Aalto, Ville and Alen, Markku and Aragaki, Aaron K and Aspelund, Thor and Center, Jacqueline R and Dailiana, Zoe and Duggan, David J and Garcia, Melissa and Garcia-Giralt, Natàlia and Giroux, Sylvie and Hallmans, Göran and Hocking, Lynne J and Husted, Lise Bjerre and Jameson, Karen A and Khusainova, Rita and Kim, Ghi Su and Kooperberg, Charles and Koromila, Theodora and Kruk, Marcin and Laaksonen, Marika and Lacroix, Andrea Z and Lee, Seung Hun and Leung, Ping C and Lewis, Joshua R and Masi, Laura and Mencej-Bedrac, Simona and Nguyen, Tuan V and Nogues, Xavier and Patel, Millan S and Prezelj, Janez and Rose, Lynda M and Scollen, Serena and Siggeirsdottir, Kristin and Smith, Albert V and Svensson, Olle and Trompet, Stella and Trummer, Olivia and van Schoor, Natasja M and Woo, Jean and Zhu, Kun and Balcells, Susana and Brandi, Maria Luisa and Buckley, Brendan M and Cheng, Sulin and Christiansen, Claus and Cooper, Cyrus and Dedoussis, George and Ford, Ian and Frost, Morten and Goltzman, David and González-Macías, Jesús and Kähönen, Mika and Karlsson, Magnus and Khusnutdinova, Elza and Koh, Jung-Min and Kollia, Panagoula and Langdahl, Bente Lomholt and Leslie, William D and Lips, Paul and Ljunggren, Östen and Lorenc, Roman S and Marc, Janja and Mellström, Dan and Obermayer-Pietsch, Barbara and Olmos, José M and Pettersson-Kymmer, Ulrika and Reid, David M and Riancho, José A and Ridker, Paul M and Rousseau, François and lagboom, P Eline S and Tang, Nelson L S and ... and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Nature genetics, ISSN 1546-1718, 04/2012, Volume 44, Issue 5, pp. 491 - 501
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Glycoproteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Computational Biology | Intercellular Signaling Peptides and Proteins - genetics | European Continental Ancestry Group | Genotype | Male | Bone Density - genetics | Gene Expression Profiling | Phosphoproteins - genetics | Fractures, Bone - genetics | Mitochondrial Membrane Transport Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Female | Femur Neck - physiopathology | Osteoporosis - genetics | Spectrin - genetics | Quantitative Trait Loci | Lumbar Vertebrae - physiopathology | Quantitative trait loci | Measurement | Fractures | Bones | Genetic aspects | Identification and classification | Density | Risk factors | Medical research | Osteoporosis | Genomics | Bone density | Gene loci | Index Medicus | Vèrtebres lumbars | Gens | Femur | Genes | Bone densitometry | Densitometria òssia | Fèmur | Lumbar vertebrae | Spectrin | Klinisk medicin | Single Nucleotide | Mitochondrial Membrane Transport Proteins | genetics | Endokrinologi och diabetes | Extracellular Matrix Proteins | Phosphoproteins | Endocrinology and Diabetes | Bone Density | Low Density Lipoprotein Receptor-Related Protein-5 | Intercellular Signaling Peptides and Proteins | Femur Neck | Glycoproteins | Clinical Medicine | physiopathology | Bone | Lumbar Vertebrae | Polymorphism
Journal Article
Journal Article
by Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B and Feitosa, Mary F and Gorski, Mathias and Tin, Adrienne and Wang, Lihua and Chu, Audrey Y and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and van der Most, Peter J and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer S and Almgren, Peter and Amin, Najaf and Ärnlöv, Johan and Bakker, Stephan J. L and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and Bottinger, Erwin P and Boutin, Thibaud S and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S and Campana, Eric and Campbell, Archie and Campbell, Harry and Canouil, Mickaël and Carroll, Robert J and Catamo, Eulalia and Chambers, John C and Chee, Miao-Ling and Chee, Miao-Li and Chen, Xu and Cheng, Ching-Yu and Cheng, Yurong and Christensen, Kaare and Cifkova, Renata and Ciullo, Marina and Concas, Maria Pina and Cook, James P and Coresh, Josef and Corre, Tanguy and Sala, Cinzia Felicita and Cusi, Daniele and Danesh, John and Daw, E. Warwick and de Borst, Martin H and De Grandi, Alessandro and de Mutsert, Renée and de Vries, Aiko P. J and Degenhardt, Frauke and Delgado, Graciela and Demirkan, Ayse and Di Angelantonio, Emanuele and Dittrich, Katalin and Divers, Jasmin and Dorajoo, Rajkumar and Eckardt, Kai-Uwe and Ehret, Georg and Elliott, Paul and Endlich, Karlhans and Evans, Michele K and Felix, Janine F and Foo, Valencia Hui Xian and Franco, Oscar H and Franke, Andre and Freedman, Barry I and Freitag-Wolf, Sandra and Friedlander, Yechiel and Froguel, Philippe and Gansevoort, Ron T and Gao, He and Gasparini, Paolo and Gaziano, J. Michael and Giedraitis, Vilmantas and Gieger, Christian and ... and V. A. Million Veteran Program and Lifelines Cohort Study and Lifelines COHort Study
Nature genetics, ISSN 1546-1718, 05/2019, Volume 51, Issue 6, pp. 957 - 972
Chronic kidney disease (CKD) is responsible for a public health burden with multi-systemic complications. Through transancestry meta-analysis of genome-wide... 
COMMON VARIANTS | METAANALYSIS | TRANSPORTER | TRANS-EQTLS | INTEGRATION | DISEASE | RENAL-FUNCTION | CLASSIFICATION | HERITABILITY | GENOME-WIDE ASSOCIATION | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Glomerular Filtration Rate | Quantitative Trait, Heritable | Humans | Genetic Association Studies - methods | European Continental Ancestry Group | Chromosome Mapping | Renal Insufficiency, Chronic - physiopathology | Kidney Function Tests | Inheritance Patterns | Phenotype | Renal Insufficiency, Chronic - genetics | Uromodulin - urine | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Renal Insufficiency, Chronic - urine | Quantitative trait loci | Genetic markers | Chronic kidney failure | Analysis | Genetic aspects | Diagnosis | Identification and classification | Glomerular filtration rate | Phenotypes | Animal models | Kidneys | Epidermal growth factor receptors | Complications | Genes | Cardiovascular disease | Mapping | Genomes | Metabolism | Gene expression | Loci | Human tissues | Meta-analysis | Studies | Urea | Population | Genetics | Gene loci | Kidney diseases | Gene mapping | Bioinformatics | Public health | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Journal Article
by Willems, Sara M and Wright, Daniel J and Day, Felix R and Trajanoska, Katerina and Joshi, Peter K and Morris, John A and Matteini, Amy M and Garton, Fleur C and Grarup, Niels and Oskolkov, Nikolay and Thalamuthu, Anbupalam and Mangino, Massimo and Liu, Jun and Demirkan, Ayse and Lek, Monkol and Xu, Liwen and Wang, Guan and Oldmeadow, Christopher and Gaulton, Kyle J and Lotta, Luca A and Miyamoto-Mikami, Eri and Rivas, Manuel A and White, Tom and Loh, Po-Ru and Aadahl, Mette and Amin, Najaf and Attia, John R and Austin, Krista and Benyamin, Beben and Brage, Søren and Cheng, Yu-Ching and Cięszczyk, Paweł and Derave, Wim and Eriksson, Karl-Fredrik and Eynon, Nir and Linneberg, Allan and Lucia, Alejandro and Massidda, Myosotis and Mitchell, Braxton D and Miyachi, Motohiko and Murakami, Haruka and Padmanabhan, Sandosh and Pandey, Ashutosh and Papadimitriou, Ioannis and Rajpal, Deepak K and Sale, Craig and Schnurr, Theresia M and Sessa, Francesco and Shrine, Nick and Tobin, Martin D and Varley, Ian and Wain, Louise V and Wray, Naomi R and Lindgren, Cecilia M and MacArthur, Daniel G and Waterworth, Dawn M and McCarthy, Mark I and Pedersen, Oluf and Khaw, Kay-Tee and Kiel, Douglas P and Pitsiladis, Yannis and Fuku, Noriyuki and Franks, Paul W and North, Kathryn N and van Duijn, Cornelia M and Mather, Karen A and Hansen, Torben and Hansson, Ola and Spector, Tim and Murabito, Joanne M and Richards, J. Brent and Rivadeneira, Fernando and Langenberg, Claudia and Perry, John R. B and Wareham, Nick J and Scott, Robert A and GEFOS Any-Type of Fracture Consortium and GEFOS Anytype Fracture Consortium and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, pp. 16015 - 16015
Journal Article