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Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 1464 - 1464
Journal Article
Journal of Natural Products, ISSN 0163-3864, 10/2019, Volume 82, Issue 10, pp. 2835 - 2841
Journal Article
MARINE DRUGS, ISSN 1660-3397, 04/2019, Volume 17, Issue 4, p. 237
Three new hydroxylated rhamnolipids, dokdolipids A-C (1-3) were obtained from the marine actinomycete Actinoalloteichus hymeniacidonis, which was isolated from... 
Actinoalloteichus hymeniacidonis | rhamnose | CHEMISTRY, MEDICINAL | biosurfactants | cytotoxicity | rhamnolipids
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 05/2019, Volume 163, pp. 46 - 59
Metastasis is the leading cause of cancer mortality and cancer cell migration is an essential stage of metastasis. We identified benproperine (Benp, a... 
Arp2/3 complex | Drug repurposing | Metastasis | ARPC2 | Benproperine | PROTEIN | INVASION | DRUGS | DISSEMINATION | PHARMACOLOGY & PHARMACY | ACTIN CYTOSKELETON | TARGET IDENTIFICATION | MOTILITY | Actin | Analysis | Polymerization | Muscle proteins | Chromatography | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 23, p. E5279
A protein synthesis enzyme, leucyl-tRNA synthetase (LRS), serves as a leucine sensor for the mechanistic target of rapamycin complex 1 (mTORC1), which is a... 
TOR protein | GTP | Amino acids | Activation | Chemoreception | Leucine | Autophagy | Protein turnover | Proteins | Signal transduction | Cell growth | GDP | Transfer RNA | Enzymes | tRNA | Protein biosynthesis | Rapamycin | Metabolism | Hydrolysis | Signaling | Protein synthesis | Leucine-tRNA ligase | Kinetics | Phagocytosis | Cancer | Guanosinetriphosphatase
Journal Article
Journal of Natural Products, ISSN 0163-3864, 11/2019, Volume 82, Issue 11, pp. 3186 - 3190
Journal Article
by Lee, HS and Kang, JS and Choi, BK and Lee, YJ and Lee, J and Shin, HJ
MARINE DRUGS, ISSN 1660-3397, 08/2019, Volume 17, Issue 8, p. 482
Three new phenazine derivatives (1-3), along with known compounds (4-7) of saphenic acid derivatives, were isolated from a deep-sea sediment-derived yeast-like... 
phenazine derivatives | CHEMISTRY, MEDICINAL | GENE | NATURAL-PRODUCTS | BIOSYNTHESIS | Cystobasidium laryngis | deep-sea sediment | saphenic acid | marine yeast-like fungi | anti-inflammatory activity
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 2017, Volume 27, Issue 3, pp. 496 - 500
Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cell. In AML, a mutation in FLT3 is commonly occurs and is associated with poor... 
FLT3 | Solubility | Thieno[2,3-d]pyrimidine | Acute myeloid leukemia (AML)
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2019, Volume 34, Issue 1, pp. 465 - 478
In our search for novel small molecules activating procaspase-3, we have designed and synthesised a series of novel acetohydrazides incorporating... 
Acetohydrazides | quinazolin-4(3H)-one | cytotoxicity | caspase activation | POTENT | CHEMISTRY, MEDICINAL | HYDROXAMIC ACIDS | PROCASPASE-3 | BIOCHEMISTRY & MOLECULAR BIOLOGY | HISTONE DEACETYLASE INHIBITORS | DISCOVERY
Journal Article
Biomaterials, ISSN 0142-9612, 07/2018, Volume 171, pp. 34 - 45
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2017, Volume 27, Issue 3, p. 496
Display Omitted 
Pyrimidines
Journal Article
Chemistry & Biodiversity, ISSN 1612-1872, 06/2018, Volume 15, Issue 6, pp. e1800027 - n/a
Journal Article
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