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Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7443, pp. 101 - 105
Cancer cells have metabolic dependencies that distinguish them from their normal counterparts(1). Among these dependencies is an increased use of the amino... 
GLUCOSE | MULTIDISCIPLINARY SCIENCES | MASS-SPECTROMETRY | ADDICTION | TRANSFORMED-CELLS | Care and treatment | Pancreatic cancer | Physiological aspects | Development and progression | Research | Health aspects | Guanosine triphosphatase | Glutamine | Cancer | Enzymes | Oxidative stress | Glucose | Metabolites | Cancer therapies
Journal Article
Nature, ISSN 0028-0836, 10/2014, Volume 514, Issue 7524, pp. 628 - 632
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2014, Volume 124, Issue 4, pp. 1525 - 1536
Background. The therapeutic resistance of pancreatic ductal adenocarcinoma (PDAC) is partly ascribed to ineffective delivery of chemotherapy to cancer cells.... 
RESECTABLE ADENOCARCINOMA | TRIAL | MEDICINE, RESEARCH & EXPERIMENTAL | THERAPY | DNA | CHEMORADIATION | PREOPERATIVE GEMCITABINE | STROMA | CARCINOMA | CHEMOTHERAPY | Pancreatic Neoplasms - metabolism | Prognosis | Prospective Studies | Antimetabolites, Antineoplastic - pharmacokinetics | DNA, Neoplasm - metabolism | Humans | Middle Aged | Carcinoma, Pancreatic Ductal - metabolism | Male | Tomography, X-Ray Computed | DNA Adducts - metabolism | Antimetabolites, Antineoplastic - administration & dosage | Carcinoma, Pancreatic Ductal - diagnostic imaging | Pancreatic Neoplasms - drug therapy | Biological Transport, Active | Deoxycytidine - pharmacokinetics | Deoxycytidine - therapeutic use | Female | Deoxycytidine - administration & dosage | Kaplan-Meier Estimate | Equilibrative Nucleoside Transporter 1 - metabolism | Carcinoma, Pancreatic Ductal - drug therapy | Antimetabolites, Antineoplastic - therapeutic use | Models, Biological | Aged | Deoxycytidine - analogs & derivatives | Pancreatic Neoplasms - diagnostic imaging | Care and treatment | Gemcitabine | Pancreatic cancer | Patient outcomes | Biological transport | Drug targeting | Dosage and administration | Research | Medical research | Medical imaging | Clinical trials | Regression analysis | Patients | Studies | Variables | Biopsy | Normal distribution | Ordinary differential equations | Mathematical models | Pancreas | Deoxyribonucleic acid--DNA | Methods | Tumors | Cancer | Clinical Medicine
Journal Article
Cancer Cell, ISSN 1535-6108, 01/2012, Volume 21, Issue 1, pp. 105 - 120
Constitutive Kras and NF-κB activation is identified as signature alterations in pancreatic ductal adenocarcinoma (PDAC). However, how NF-κB is activated in... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 2741 - 2741
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 116 - 116
Journal Article
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 36, pp. 8428 - 8437
Irinotecan-based therapy is a common treatment for pancreatic cancer. To elicit its anticancer activity, the drug requires first the hydrolysis action of the... 
Chemical sensors | Therapy | Level (quantity) | Pancreatic cancer | Xenotransplantation | Fluorescence | Measurement methods | Patients | Chemoreceptors | Anticancer properties
Journal Article
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 04/2017, Volume 16, Issue 4, pp. 662 - 670
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2016, Volume 34, Issue 4_suppl, pp. 235 - 235
Journal Article
Journal Article
Surgery: Official Journal of the Society of University Surgeons, Central Surgical Association, and the American Association of Endocrine Surgeons, ISSN 0039-6060, 2016, Volume 161, Issue 5, pp. 1246 - 1254
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2016, Volume 34, Issue 4_suppl, pp. 236 - 236
Journal Article