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by Nikpay, Majid and Goel, Anuj and Won, Hong-Hee and Hall, Leanne M and Willenborg, Christina and Kanoni, Stavroula and Saleheen, Danish and Kyriakou, Theodosios and Nelson, Christopher P and CHopewell, Jemma and Webb, Thomas R and Zeng, Lingyao and Dehghan, Abbas and Alver, Maris and MArmasu, Sebastian and Auro, Kirsi and Bjonnes, Andrew and Chasman, Daniel I and Chen, Shufeng and Ford, Ian and Franceschini, Nora and Gieger, Christian and Grace, Christopher and Gustafsson, Stefan and Huang, Jie and Hwang, Shih-Jen and Kim, Yun Kyoung and Kleber, Marcus E and Lau, King Wai and Lu, Xiangfeng and Lu, Yingchang and Lyytikäinen, Leo-Pekka and Mihailov, Evelin and Morrison, Alanna C and Pervjakova, Natalia and Qu, Liming and Rose, Lynda M and Salfati, Elias and Saxena, Richa and Scholz, Markus and Smith, Albert V and Tikkanen, Emmi and Uitterlinden, Andre and Yang, Xueli and Zhang, Weihua and Zhao, Wei and De Andrade, Mariza and De Vries, Paul S and Van Zuydam, Natalie R and Anand, Sonia S and Bertram, Lars and Beutner, Frank and Dedoussis, George and Frossard, Philippe and Gauguier, Dominique and Goodall, Alison H and Gottesman, Omri and Haber, Marc and Han, Bok-Ghee and Huang, Jianfeng and Jalilzadeh, Shapour and Kessler, Thorsten and König, Inke R and Lannfelt, Lars and Lieb, Wolfgang and Lind, Lars and MLindgren, Cecilia and Lokki, Marja-Liisa and Magnusson, Patrik K and Mallick, Nadeem H and Mehra, Narinder and Meitinger, Thomas and Memon, Fazal-Uur-Rehman and Morris, Andrew P and Nieminen, Markku S and Pedersen, Nancy L and Peters, Annette and Rallidis, Loukianos S and Rasheed, Asif and Samuel, Maria and Shah, Svati H and Sinisalo, Juha and EStirrups, Kathleen and Trompet, Stella and Wang, Laiyuan and Zaman, Khan S and Ardissino, Diego and Boerwinkle, Eric and Borecki, Ingrid B and Bottinger, Erwin P and Buring, Julie E and Chambers, John C and Collins, Rory and Cupples, Ladrienne and Danesh, John and Demuth, Ilja and Elosua, Roberto and Epstein, Stephen E and Esko, Tõnu and Feitosa, Mary F and ... and the CARDIoGRAMplusC4D Consortium and CARDIoGRAMplusC4D Consortium
Nature genetics, ISSN 1546-1718, 2015, Volume 47, Issue 10, pp. 1121 - 1130
Journal Article
by Liu, Dajiang J and Peloso, Gina M and Yu, Haojie and Butterworth, Adam S and Wang, Xiao and Mahajan, Anubha and Saleheen, Danish and Emdin, Connor and Alam, Dewan and Alves, Alexessander Couto and Amouyel, Philippe and Di Angelantonio, Emanuele and Arveiler, Dominique and Assimes, Themistocles L and Auer, Paul L and Baber, Usman and Ballantyne, Christie M and Bang, Lia E and Benn, Marianne and Bis, Joshua C and Boehnke, Michael and Boerwinkle, Eric and Bork-Jensen, Jette and Bottinger, Erwin P and Brandslund, Ivan and Brown, Morris and Busonero, Fabio and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Y Eugene and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Connell, John M and Cucca, Francesco and Cupples, L Adrienne and Damrauer, Scott M and Davies, Gail and Deary, Ian J and Dedoussis, George and Denny, Joshua C and Dominiczak, Anna and Dubé, Marie-Pierre and Ebeling, Tapani and Eiriksdottir, Gudny and Esko, Tõnu and Farmaki, Aliki-Eleni and Feitosa, Mary F and Ferrario, Marco and Ferrieres, Jean and Ford, Ian and Fornage, Myriam and Franks, Paul W and Frayling, Timothy M and Frikke-Schmidt, Ruth and Fritsche, Lars G and Frossard, Philippe and Fuster, Valentin and Ganesh, Santhi K and Gao, Wei and Garcia, Melissa E and Gieger, Christian and Giulianini, Franco and Goodarzi, Mark O and Grallert, Harald and Grarup, Niels and Groop, Leif and Grove, Megan L and Gudnason, Vilmundur and Hansen, Torben and Harris, Tamara B and Hayward, Caroline and Hirschhorn, Joel N and Holmen, Oddgeir L and Huffman, Jennifer and Huo, Yong and Hveem, Kristian and Jabeen, Sehrish and Jackson, Anne U and Jakobsdottir, Johanna and Jarvelin, Marjo-Riitta and Jensen, Gorm B and Jørgensen, Marit E and Jukema, J Wouter and Justesen, Johanne M and Kamstrup, Pia R and Kanoni, Stavroula and Karpe, Fredrik and Kee, Frank and Khera, Amit V and Klarin, Derek and Koistinen, Heikki A and Kooner, Jaspal S and Kooperberg, Charles and Kuulasmaa, Kari and Kuusisto, Johanna and Laakso, Markku and Lakka, Timo and ... and VA Million Veteran Program and Charge Diabet Working Grp and EPIC-CVD Consortium and EPIC-InterAct Consortium and GOLD Consortium and Charge Diabetes Working Group and The EPIC-InterAct Consortium
Nature genetics, ISSN 1546-1718, 2017, Volume 49, Issue 12, pp. 1758 - 1766
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent... 
APOBEC-1 COMPLEMENTATION FACTOR | MYELOPROLIFERATIVE DISORDERS | LOW-FREQUENCY | CLONAL HEMATOPOIESIS | B MESSENGER-RNA | GENETICS & HEREDITY | TYROSINE KINASE JAK2 | CARDIOVASCULAR-DISEASE | MACULAR DEGENERATION | GENETIC ARCHITECTURE | CODING-SEQUENCE VARIANTS | Genetic Predisposition to Disease - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Genetic Association Studies - methods | Genotype | Coronary Artery Disease - blood | Macular Degeneration - blood | Genetic Variation | Diabetes Mellitus, Type 2 - blood | Exome - genetics | Phenotype | Macular Degeneration - genetics | Lipids - blood | Coronary Artery Disease - genetics | Genome-wide association studies | Genetic aspects | Blood lipids | Identification and classification | Methods | Plasma | Lipoproteins (low density) | Liver | Lipids | Risk | Cardiovascular disease | Genomes | Macular degeneration | Consortia | Janus kinase 2 | Heart diseases | Lipoproteins (high density) | Age | Diabetes mellitus | Coronary artery | Health risks | Thalassemia | Triglycerides | Coronary artery disease | Loci | Cholesterol | Lipolysis | Studies | Lipoproteins | Genotyping | Alleles | Quality control | Diabetes | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 372, Issue 17, pp. 1608 - 1618
Journal Article
by Kilpeläinen, Tuomas O and Qi, Lu and Brage, Soren and Sharp, Stephen J and Sonestedt, Emily and Demerath, Ellen and Ahmad, Tariq and Mora, Samia and Kaakinen, Marika and Sandholt, Camilla Helene and Holzapfel, Christina and Autenrieth, Christine S and Hyppönen, Elina and Cauchi, Stéphane and He, Meian and Kutalik, Zoltan and Kumari, Meena and Stančáková, Alena and Meidtner, Karina and Balkau, Beverley and Tan, Jonathan T and Mangino, Massimo and Timpson, Nicholas J and Song, Yiqing and Zillikens, M. Carola and Jablonski, Kathleen A and Garcia, Melissa E and Johansson, Stefan and Bragg-Gresham, Jennifer L and Wu, Ying and van Vliet-Ostaptchouk, Jana V and Onland-Moret, N. Charlotte and Zimmermann, Esther and Rivera, Natalia V and Tanaka, Toshiko and Stringham, Heather M and Silbernagel, Günther and Kanoni, Stavroula and Feitosa, Mary F and Snitker, Soren and Ruiz, Jonatan R and Metter, Jeffery and Larrad, Maria Teresa Martinez and Atalay, Mustafa and Hakanen, Maarit and Amin, Najaf and Cavalcanti-Proença, Christine and Grøntved, Anders and Hallmans, Göran and Jansson, John-Olov and Kuusisto, Johanna and Kähönen, Mika and Lutsey, Pamela L and Nolan, John J and Palla, Luigi and Pedersen, Oluf and Pérusse, Louis and Renström, Frida and Scott, Robert A and Shungin, Dmitry and Sovio, Ulla and Tammelin, Tuija H and Rönnemaa, Tapani and Lakka, Timo A and Uusitupa, Matti and Rios, Manuel Serrano and Ferrucci, Luigi and Bouchard, Claude and Meirhaeghe, Aline and Fu, Mao and Walker, Mark and Borecki, Ingrid B and Dedoussis, George V and Fritsche, Andreas and Ohlsson, Claes and Boehnke, Michael and Bandinelli, Stefania and van Duijn, Cornelia M and Ebrahim, Shah and Lawlor, Debbie A and Gudnason, Vilmundur and Harris, Tamara B and Sørensen, Thorkild I. A and Mohlke, Karen L and Hofman, Albert and Uitterlinden, André G and Tuomilehto, Jaakko and Lehtimäki, Terho and Raitakari, Olli and Isomaa, Bo and Njølstad, Pål R and Florez, Jose C and Liu, Simin and Ness, Andy and Spector, Timothy D and Tai, E. Shyong and Froguel, Philippe and Boeing, Heiner and Laakso, Markku and Marmot, Michael and ... and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Physiology and Institutionen för medicin, avdelningen för invärtesmedicin and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi and Institute of Medicine, Department of Internal Medicine
PLoS medicine, ISSN 1549-1676, 2011, Volume 8, Issue 11, p. e1001116
Journal Article
by Webb, Thomas R and Erdmann, Jeanette and Stirrups, Kathleen E and Stitziel, Nathan O and Masca, Nicholas G.D and Jansen, Henning and Kanoni, Stavroula and Nelson, Christopher P and Ferrario, Paola G and König, Inke R and Eicher, John D and Johnson, Andrew D and Hamby, Stephen E and Betsholtz, Christer and Ruusalepp, Arno and Franzén, Oscar and Schadt, Eric E and Björkegren, Johan L.M and Weeke, Peter E and Auer, Paul L and Schick, Ursula M and Lu, Yingchang and Zhang, He and Dube, Marie-Pierre and Goel, Anuj and Farrall, Martin and Peloso, Gina M and Won, Hong-Hee and Do, Ron and van Iperen, Erik and Kruppa, Jochen and Mahajan, Anubha and Scott, Robert A and Willenborg, Christina and Braund, Peter S and van Capelleveen, Julian C and Doney, Alex S.F and Donnelly, Louise A and Asselta, Rosanna and Merlini, Pier A and Duga, Stefano and Marziliano, Nicola and Denny, Josh C and Shaffer, Christian and El-Mokhtari, Nour Eddine and Franke, Andre and Heilmann, Stefanie and Hengstenberg, Christian and Hoffmann, Per and Holmen, Oddgeir L and Hveem, Kristian and Jansson, Jan-Håkan and Jöckel, Karl-Heinz and Kessler, Thorsten and Kriebel, Jennifer and Laugwitz, Karl L and Marouli, Eirini and Martinelli, Nicola and McCarthy, Mark I and Van Zuydam, Natalie R and Meisinger, Christa and Esko, Tõnu and Mihailov, Evelin and Escher, Stefan A and Alver, Maris and Moebus, Susanne and Morris, Andrew D and Virtamo, Jarma and Nikpay, Majid and Olivieri, Oliviero and Provost, Sylvie and AlQarawi, Alaa and Robertson, Neil R and Akinsansya, Karen O and Reilly, Dermot F and Vogt, Thomas F and Yin, Wu and Asselbergs, Folkert W and Kooperberg, Charles and Jackson, Rebecca D and Stahl, Eli and Müller-Nurasyid, Martina and Strauch, Konstantin and Varga, Tibor V and Waldenberger, Melanie and Zeng, Lingyao and Chowdhury, Rajiv and Salomaa, Veikko and Ford, Ian and Jukema, J. Wouter and Amouyel, Philippe and Kontto, Jukka and Nordestgaard, Børge G and Ferrières, Jean and Saleheen, Danish and Sattar, Naveed and Surendran, Praveen and Wagner, Aline and Young, Robin and Howson, Joanna M.M and ... and Wellcome Trust Case Control Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators and MORGAM Investigators and Wellcome Trust Case Control and Myocardial Infarction Genetics
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 823 - 836
Abstract Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show... 
Cardiovascular | Internal Medicine | expression quantitative trait loci | genetics | genome-wide association | single nucleotide polymorphism | cholesteryl ester transfer protein | SR-BI | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | CETP MASS | SUSCEPTIBILITY | RISK | PHOSPHOLIPASE A | VARIANT | SCAVENGER RECEPTOR | ABDOMINAL AORTIC-ANEURYSM | Genome-Wide Association Study | Gene Frequency | Humans | Coronary Artery Disease - genetics | Female | Male | Coronary Artery Disease - epidemiology | Genetic Pleiotropy | Polymorphism, Single Nucleotide | Genetic Loci | Odds Ratio | Case-Control Studies | Coronary heart disease | Analysis | Genealogy | Cardiovascular disease | Genomes | Metabolism | Gene expression | Blood | Risk factors | Studies | Celiac disease | Lipoproteins | Coronary vessels | Rheumatoid arthritis | Quality control | Calcification | Diabetes | Bioinformatics | LD, linkage disequilibrium | CETP, cholesteryl ester transfer protein | eQTL, expression quantitative trait locus | CAD, coronary artery disease | GWAS, genome-wide association study | BMI, body mass index | SNP, single nucleotide polymorphism | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin
Journal Article
by Gieger, Christian and Radhakrishnan, Aparna and Cvejic, Ana and Tang, Weihong and Porcu, Eleonora and Pistis, Giorgio and Serbanovic-Canic, Jovana and Elling, Ulrich and Goodall, Alison H and Labrune, Yann and Lopez, Lorna M and Mägi, Reedik and Meacham, Stuart and Okada, Yukinori and Pirastu, Nicola and Sorice, Rossella and Teumer, Alexander and Voss, Katrin and Zhang, Weihua and Ramirez-Solis, Ramiro and Bis, Joshua C and Ellinghaus, David and Gögele, Martin and Hottenga, Jouke-Jan and Langenberg, Claudia and Kovacs, Peter and O’Reilly, Paul F and Shin, So-Youn and Esko, Tõnu and Hartiala, Jaana and Kanoni, Stavroula and Murgia, Federico and Parsa, Afshin and Stephens, Jonathan and van der Harst, Pim and Ellen van der Schoot, C and Allayee, Hooman and Attwood, Antony and Balkau, Beverley and Bastardot, François and Basu, Saonli and Baumeister, Sebastian E and Biino, Ginevra and Bomba, Lorenzo and Bonnefond, Amélie and Cambien, François and Chambers, John C and Cucca, Francesco and D’Adamo, Pio and Davies, Gail and de Boer, Rudolf A and de Geus, Eco J. C and Döring, Angela and Elliott, Paul and Erdmann, Jeanette and Evans, David M and Falchi, Mario and Feng, Wei and Folsom, Aaron R and Frazer, Ian H and Gibson, Quince D and Glazer, Nicole L and Hammond, Chris and Hartikainen, Anna-Liisa and Heckbert, Susan R and Hengstenberg, Christian and Hersch, Micha and Illig, Thomas and Loos, Ruth J. F and Jolley, Jennifer and Khaw, Kay-Tee and Kühnel, Brigitte and Kyrtsonis, Marie-Christine and Lagou, Vasiliki and Lloyd-Jones, Heather and Lumley, Thomas and Mangino, Massimo and Maschio, Andrea and Mateo Leach, Irene and McKnight, Barbara and Memari, Yasin and Mitchell, Braxton D and Montgomery, Grant W and Nakamura, Yusuke and Nauck, Matthias and Navis, Gerjan and Nöthlings, Ute and Nolte, Ilja M and Porteous, David J and Pouta, Anneli and Pramstaller, Peter P and Pullat, Janne and Ring, Susan M and Rotter, Jerome I and Ruggiero, Daniela and Ruokonen, Aimo and Sala, Cinzia and Samani, Nilesh J and Sambrook, Jennifer and Schlessinger, David and ...
Nature (London), ISSN 1476-4687, 2011, Volume 480, Issue 7376, pp. 201 - 208
Journal Article
by van der Harst, Pim and Zhang, Weihua and Mateo Leach, Irene and Rendon, Augusto and Verweij, Niek and Sehmi, Joban and Paul, Dirk S and Elling, Ulrich and Allayee, Hooman and Li, Xinzhong and Radhakrishnan, Aparna and Tan, Sian-Tsung and Voss, Katrin and Weichenberger, Christian X and Albers, Cornelis A and Al-Hussani, Abtehale and Asselbergs, Folkert W and Ciullo, Marina and Danjou, Fabrice and Dina, Christian and Esko, Tõnu and Evans, David M and Franke, Lude and Gögele, Martin and Hartiala, Jaana and Hersch, Micha and Holm, Hilma and Hottenga, Jouke-Jan and Kanoni, Stavroula and Kleber, Marcus E and Lagou, Vasiliki and Langenberg, Claudia and Lopez, Lorna M and Lyytikäinen, Leo-Pekka and Melander, Olle and Murgia, Federico and Nolte, Ilja M and O’Reilly, Paul F and Padmanabhan, Sandosh and Parsa, Afshin and Pirastu, Nicola and Porcu, Eleonora and Portas, Laura and Prokopenko, Inga and Ried, Janina S and Shin, So-Youn and Tang, Clara S and Teumer, Alexander and Traglia, Michela and Ulivi, Sheila and Westra, Harm-Jan and Yang, Jian and Hua Zhao, Jing and Anni, Franco and Abdellaoui, Abdel and Attwood, Antony and Balkau, Beverley and Bandinelli, Stefania and Bastardot, François and Benyamin, Beben and Boehm, Bernhard O and Cookson, William O and Das, Debashish and de Bakker, Paul I. W and de Boer, Rudolf A and de Geus, Eco J. C and de Moor, Marleen H and Dimitriou, Maria and Domingues, Francisco S and Döring, Angela and Engström, Gunnar and Ingi Eyjolfsson, Gudmundur and Ferrucci, Luigi and Fischer, Krista and Galanello, Renzo and Garner, Stephen F and Genser, Bernd and Gibson, Quince D and Girotto, Giorgia and Fannar Gudbjartsson, Daniel and Harris, Sarah E and Hartikainen, Anna-Liisa and Hastie, Claire E and Hedblad, Bo and Illig, Thomas and Jolley, Jennifer and Kähönen, Mika and Kema, Ido P and Kemp, John P and Liang, Liming and Lloyd-Jones, Heather and Loos, Ruth J. F and Meacham, Stuart and Medland, Sarah E and Meisinger, Christa and Memari, Yasin and Mihailov, Evelin and Miller, Kathy and Moffatt, Miriam F and Nauck, Matthias and ...
Nature (London), ISSN 1476-4687, 2012, Volume 492, Issue 7429, pp. 369 - 375
Journal Article