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1. Full Text Long-term Effects of Intravenous Cyclophosphamide in Combination with Mesna Provided Intravenously and via Bladder Perfusion in a Patient with Severe Multifocal Motor Neuropathy
by Iwasawa, Eri and Ohkubo, Takuya and Kanouchi, Tadashi and Kanda, Takashi and Mizusawa, Hidehiro and Yokota, Takanori
Internal Medicine, ISSN 0918-2918, 2017, Volume 56, Issue 14, pp. 1893 - 1896
A 25-year-old woman presenting with progressive muscle weakness in the distal extremities in the absence of sensory involvement for 2 years was diagnosed with... 
multifocal motor neuropathy (MMN) | cyclophosphamide | Cyclophosphamide | Multifocal motor neuropathy (MMN) | NEUROLOGICAL SOCIETIES | TRIAL | 1ST REVISION | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | CONDUCTION BLOCK | PERIPHERAL-NERVE SOCIETY | JOINT TASK-FORCE | EUROPEAN FEDERATION | GUIDELINE | Cyclophosphamide - administration & dosage | Humans | Immunosuppressive Agents - therapeutic use | Polyneuropathies - drug therapy | Mesna - therapeutic use | Cyclophosphamide - adverse effects | Cyclophosphamide - therapeutic use | Cystitis - drug therapy | Administration, Intravenous | Mesna - adverse effects | Muscle Weakness | Adult | Female | Immunosuppressive Agents - adverse effects | Immunosuppressive Agents - administration & dosage | Mesna - administration & dosage | Therapy | Intravenous administration | Bladder | Muscles | Neuropathy | Hemorrhage | Disease control | Immunosuppressive agents | Urinary bladder | Perfusion | Ventilation | Hemorrhagic cystitis | Cystitis | Extremities | Long-term effects | Case Report
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2. Full Text Spreading of amyotrophic lateral sclerosis lesions—multifocal hits and local propagation?
by Sekiguchi, Teruhiko and Kanouchi, Tadashi and Shibuya, Kazumoto and Noto, Yu-ichi and Yagi, Yohsuke and Inaba, Akira and Abe, Keisuke and Misawa, Sonoko and Orimo, Satoshi and Kobayashi, Takayoshi and Kamata, Tomoyuki and Nakagawa, Masanori and Kuwabara, Satoshi and Mizusawa, Hidehiro and Yokota, Takanori
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 01/2014, Volume 85, Issue 1, pp. 85 - 91
Objective To investigate whether or not the lesions in sporadic amyotrophic lateral sclerosis (ALS) originate from a single focal onset site and spread... 
SURVIVAL | SURGERY | DIAGNOSIS | LOCALIZATION | PSYCHIATRY | SENSITIVITY | VULNERABILITY | SYMPTOMS | CLINICAL NEUROLOGY | MOTOR | AWAJI ALS CRITERIA | PARASPINAL MUSCLES | ONSET | Data Interpretation, Statistical | Motor Neurons - physiology | Humans | Middle Aged | Male | Disease Progression | Amyotrophic Lateral Sclerosis - pathology | Aged, 80 and over | Adult | Female | Aged | Electromyography | Muscle, Skeletal - pathology | Amyotrophic lateral sclerosis | Development and progression | Usage
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3. Full Text Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol
by Nishina, Kazutaka and Unno, Toshinori and Uno, Yoshitaka and Kubodera, Takayuki and Kanouchi, Tadashi and Mizusawa, Hidehiro and Yokota, Takanori
Molecular Therapy, ISSN 1525-0016, 04/2008, Volume 16, Issue 4, pp. 734 - 740
RNA interference is a powerful tool for target-specific knockdown of gene expression. However, efficient and safe delivery of short interfering RNA (siRNA) to... 
MEDICINE, RESEARCH & EXPERIMENTAL | SMALL INTERFERING RNA | CELLS | VITAMIN-E | TRANSPORT | DESIGN | POTENT | GENE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | MICE | RNA, Small Interfering - genetics | Apolipoproteins B - metabolism | Liver - metabolism | Gene Silencing | alpha-Tocopherol | Apolipoproteins B - genetics | RNA, Messenger - metabolism | Drug Carriers | Animals | Cell Line, Tumor | Interferons - metabolism | Mice | RNA, Small Interfering - administration & dosage
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4. Full Text Safety and efficacy of eculizumab in Guillain-Barré syndrome: a multicentre, double-blind, randomised phase 2 trial
by Misawa, S and Misawa, Sonoko and Kuwabara, Satoshi and Kuwabara, S and Sato, Y and Sato, Yasunori and Yamaguchi, N and Yamaguchi, Nobuko and Yamaguchi, H and Nagashima, Kengo and Nagashima, T and Nagashima, K and Katayama, K and Katayama, Kanako and Sekiguchi, Y and Sekiguchi, Yukari and Iwai, Y and Iwai, Yuta and Amino, H and Amino, Hiroshi and Suichi, Tomoki and Suichi, T and Yokota, T and Yokota, Takanori and Nishida, Yoichiro and Nishida, Y and Kanouchi, Tadashi and Kanouchi, T and Kohara, Nobuo and Kohara, N and Kawamoto, M and Kawamoto, Michi and Ishii, Junko and Ishii, J and Kuwahara, M and Kuwahara, Motoi and Suzuki, Hidekazu and Suzuki, Shigeaki and Suzuki, S and Suzuki, Norihiro and Suzuki, H and Suzuki, N and Hirata, Koichi and Hirata, K and Kokubun, Norito and Kokubun, N and Masuda, R and Masuda, Ray and Kaneko, J and Kaneko, Juntaro and Yabe, Ichiro and Yabe, I and Sasaki, Hidenao and Sasaki, H and Kaida, Ken-ichi and Kaida, K and Takazaki, Hiroshi and Takazaki, H and Nodera, Hiroyuki and Nodera, H and Matsui, N and Matsui, Naoko and Tsuji, S and Tsuji, Shoji and Koike, Haruki and Koike, H and Yamasaki, Ryo and Yamasaki, R and Kusunoki, S and Kusunoki, Susumu and Shimizu, J and Shimizu, T and Hirotani, M and Kadoya, M and Nakahara, J and Tanaka, M and Sobue, G and Katsuno, M and Ogata, H and Japanese Eculizumab Trial GBS and Japanese Eculizumab Trial for GBS (JET-GBS) Study Group
The Lancet Neurology, ISSN 1474-4422, 06/2018, Volume 17, Issue 6, pp. 519 - 529
Despite the introduction of plasmapheresis and immunoglobulin therapy, many patients with Guillain-Barré syndrome still have an incomplete recovery. Evidence... 
ANTIBODIES | COMPLEMENT | INHIBITION | NEUROPATHY | INTRAVENOUS IMMUNOGLOBULIN | SCALE | CLINICAL NEUROLOGY | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Guillain-Barre Syndrome - drug therapy | Humans | Japan | Middle Aged | Male | Treatment Outcome | Motor Activity | Recovery of Function | Adult | Female | Aged | Guillain-Barre syndrome | Clinical trials | Analysis | Immunoglobulins | Intravenous administration | Infections | Complement | Hemorrhage | Plasmapheresis | Studies | Anaphylaxis | Complement component C5 | Monoclonal antibodies | Ventilation | Safety
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5. Full Text Nerve conduction study of the association between glycemic variability and diabetes neuropathy
by Akaza, Miho and Akaza, Itaru and Kanouchi, Tadashi and Sasano, Tetsuo and Sumi, Yuki and Yokota, Takanori
Diabetology and Metabolic Syndrome, ISSN 1758-5996, 09/2018, Volume 10, Issue 1, pp. 69 - 8
Background: It remains unclear whether glycemic variability is related to diabetes microvascular disease, especially diabetes peripheral neuropathy (DPN). We... 
Continuous glucose monitoring | Nerve conduction study | Diabetes peripheral neuropathy | Glycemic variability | CARDIOVASCULAR AUTONOMIC NEUROPATHY | OXIDATIVE STRESS | EXCURSIONS | ACTIVATION | GLUCOSE VARIABILITY | PREVALENCE | RISK-FACTOR | ENDOCRINOLOGY & METABOLISM | PERIPHERAL NEUROPATHY | RETINOPATHY | COMPLICATIONS | Complications and side effects | Control | Care and treatment | Blood sugar | Analysis | Diabetes | Quality of life
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6. Full Text Utility of Autonomic Function Tests to Differentiate Dementia with Lewy Bodies and Parkinson Disease with Dementia from Alzheimer Disease
by Toru, Shuta and Kanouchi, Tadashi and Yokota, Takanori and Yagi, Yosuke and Machida, Akira and Kobayashi, Takayoshi
European Neurology, ISSN 0014-3022, 03/2018, Volume 79, Issue 1-2, pp. 27 - 32
Objective: We studied autonomic disturbance in patients with dementia with Lewy bodies (DLB), Parkinson disease with dementia (PDD), Alzheimer disease (AD), to... 
Original Paper | autonomic function tests | Parkinson disease with dementia | Alzheimer disease | Dementia with Lewy bodies | SYMPATHETIC SKIN-RESPONSE | CLINICAL-DIAGNOSIS | BODY-DISEASE | FAILURE | NEUROSCIENCES | CLINICAL NEUROLOGY | Autonomic Nervous System Diseases - epidemiology | Parkinson Disease - complications | Autonomic Nervous System Diseases - etiology | Alzheimer Disease - complications | Humans | Dementia - diagnosis | Male | Autonomic Nervous System - physiopathology | Alzheimer Disease - diagnosis | Dementia - etiology | Parkinson Disease - diagnosis | Female | Aged | Tilt-Table Test
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7. Full Text 2. Compound nerve action potential (CNAP) study is a useful examination for evaluating muscle afferent Ia fibers
by Abe, Keisuke and Kanouchi, Tadashi and Sekiguchi, Teruhiko and Mizusawa, Hidehiro and Yokota, Takanori
Clinical Neurophysiology, ISSN 1388-2457, 2011, Volume 122, Issue 8, pp. e9 - e9
Neurology
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8. Full Text Motor nerve conduction study in cauda equina with high‐voltage electrical stimulation in multifocal motor neuropathy and amyotrophic lateral sclerosis
by Akaza, Miho and Kanouchi, Tadashi and Inaba, Akira and Numasawa, Yoshiyuki and Irioka, Takashi and Mizusawa, Hidehiro and Yokota, Takanori
Muscle & Nerve, ISSN 0148-639X, 02/2011, Volume 43, Issue 2, pp. 274 - 282
In this study we aim to establish a motor nerve conduction study (NCS) for the cauda equina and examine its usefulness in multifocal motor neuropathy (MMN) and... 
multifocal motor neuropathy | amyotrophic lateral sclerosis | high‐voltage electrical stimulation | cauda equina | multifocal motor neuropathy without conduction block | Multifocal motor neuropathy | Amyotrophic lateral sclerosis | High-voltage electrical stimulation | Multifocal motor neuropathy without conduction block | Cauda equina | PATHWAYS | CRITERIA | VELOCITY | DIAGNOSIS | BLOCK | high-voltage electrical stimulation | POTENTIALS | NEUROSCIENCES | CLINICAL NEUROLOGY | CENTRAL SEGMENT | MAGNETIC STIMULATION | F-WAVE | DOUBLE-BLIND | Cauda Equina - physiology | Electric Stimulation | Amyotrophic Lateral Sclerosis - therapy | Humans | Middle Aged | Hip - innervation | Male | Neural Conduction - physiology | Cauda Equina - physiopathology | Polyneuropathies - therapy | Magnetics | Action Potentials - physiology | Young Adult | Tibial Nerve - physiopathology | Knee - innervation | Ankle - innervation | Muscle, Skeletal - physiopathology | Aged, 80 and over | Adult | Female | Aged | Electromyography - methods
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9. Full Text New tests that are necessary and those that are important to clinical practitioners. 8. Neuromuscular diseases
by Kanouchi, Tadashi and Mizusawa, Hidehiro
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, ISSN 0021-5384, 12/2008, Volume 97, Issue 12, p. 2998
Action Potentials | Humans | Neural Conduction | Neuromuscular Diseases - diagnosis
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10. Full Text New tests that are necessary and those that are important to clinical practitioners. 8. Neuromuscular diseases
by Kanouchi, Tadashi and Mizusawa, Hidehiro
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, ISSN 0021-5384, 12/2008, Volume 97, Issue 12, pp. 2998 - 3005
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11. Full Text 52. Study of albumin leakage and peripheral nerve-conduction study in Guillain–Barré syndrome
by Akaza, Miho and Kanouchi, Tadashi and Kamata, Tomoyuki and Yokota, Takanori and Mizusawa, Hidehiro
Clinical Neurophysiology, ISSN 1388-2457, 2008, Volume 119, Issue 6, pp. e87 - e88
Neurology
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12. Full Text 8. Neuromuscular Diseases
by Kanouchi, Tadashi and Mizusawa, Hidehiro
Nihon Naika Gakkai Zasshi, ISSN 0021-5384, 2008, Volume 97, Issue 12, pp. 2998 - 3005
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13. Full Text Whether or not ALS lesions spread contiguously?
by Kanouchi, Tadashi and Sekiguchi, Teruhiko and Mizusawa, Hidehiro and Yokota, Takanori
Clinical Neurology, ISSN 0009-918X, 2012, Volume 52, Issue 11, pp. 1059 - 1061
Local progression | Amyotrophic lateral sclerosis | Regional spread | Prion-like propagation
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14. Full Text 137. New feature of nerve conduction in anti-MAG antibody associated neuropathy
by Soga, Kazumasa and Kanouchi, Tadashi and Hashimoto, Yuji and Yamanami, Ayaka and Tomimitsu, Hiroyuki and Sekiguchi, Teruhiko and Yokota, Takanori and Mizusawa, Hidehiro
Clinical Neurophysiology, ISSN 1388-2457, 2009, Volume 120, Issue 5, pp. e178 - e178
Neurology
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15. Full Text Bax-inhibiting peptide derived from mouse and rat Ku70
by Yoshida, Tomoyuki and Tomioka, Ikuo and Nagahara, Takako and Holyst, Trudy and Sawada, Motoshi and Hayes, Paulette and Gama, Vivian and Okuno, Misako and Chen, Yuhong and Abe, Yasuyuki and Kanouchi, Tadashi and Sasada, Hiroshi and Wang, Demin and Yokota, Takanori and Sato, Eimei and Matsuyama, Shigemi
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2004, Volume 321, Issue 4, pp. 961 - 966
Bax is a proapoptotic protein that plays a key role in the induction of apoptosis. Ku70 has activities to repair DNA damage in the nucleus and to suppress... 
Ku70 | Bax | Bax inhibiting peptide | Apoptosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | IDENTIFICATION | MATURATION | CONFORMATIONS | CYTOCHROME-C | BIOPHYSICS | NEURONAL DEATH | FOLLICLE-STIMULATING-HORMONE | SURVIVAL SIGNALS | CUMULUS CELLS | OOCYTES | Antigens, Nuclear - metabolism | Apoptosis - drug effects | Humans | Molecular Sequence Data | Ovary - cytology | DNA-Binding Proteins - metabolism | Antigens, Nuclear - chemistry | Female | Ovary - drug effects | Oligopeptides - chemistry | Ovary - metabolism | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | Cells, Cultured | Etoposide - pharmacology | Rats | Oligopeptides - metabolism | bcl-2-Associated X Protein | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Sequence Homology, Amino Acid | Animals | Antigens, Nuclear - genetics | Ku Autoantigen | Mice | Proto-Oncogene Proteins c-bcl-2 | Oligopeptides - pharmacology | Peptides | Cell death | Universities and colleges
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16. Whether or not ALS lesions spread contiguously?
by Kanouchi, Tadashi and Sekiguchi, Teruhiko and Mizusawa, Hidehiro and Yokota, Takanori
Rinsho shinkeigaku = Clinical neurology, 2012, Volume 52, Issue 11, p. 1059
Using clinical information, it was investigated whether lesions in sporadic amyotrophic lateral sclerosis (sALS) spread contiguously from an onset site to the... 
Amyotrophic Lateral Sclerosis - pathology | Humans | Disease Progression
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17. Full Text Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of [alpha]-Tocopherol
by Kazutaka Nishina and Toshinori Unno and Yoshitaka Uno and Takayuki Kubodera and Tadashi Kanouchi and Hidehiro Mizusawa and Takanori Yokota
Molecular Therapy, ISSN 1525-0016, 04/2008, Volume 16, Issue 4, p. 734
  RNA interference is a powerful tool for target-specific knockdown of gene expression. However, efficient and safe in vivo delivery of short interfering RNA... 
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18. Full Text Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol
by Nishina, Kazutaka and Unno, Toshinori and Uno, Yoshitaka and Kubodera, Takayuki and Kanouchi, Tadashi and Mizusawa, Hidehiro and Yokota, Takanori
Molecular therapy : the journal of the American Society of Gene Therapy, ISSN 1525-0016, 04/2008, Volume 16, Issue 4, p. 734
RNA interference is a powerful tool for target-specific knockdown of gene expression. However, efficient and safe in vivo delivery of short interfering RNA... 
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19. Full Text Chiasmal optic neuritis following mumps parotitis
by Irioka, T and Akaza, M and Nakao, K and Kanouchi, T and Yokota, T and Mizusawa, H
Journal of Neurology, ISSN 0340-5354, 5/2008, Volume 255, Issue 5, pp. 773 - 774
Neurology | Neurosciences | Medicine & Public Health | Neuroradiology | SECONDARY | BARR VIRUS-INFECTION | CLINICAL NEUROLOGY | Diagnosis, Differential | Humans | Retina - physiopathology | Hemianopsia - diagnosis | Treatment Outcome | Optic Neuritis - diagnosis | Demyelinating Autoimmune Diseases, CNS - diagnosis | Optic Chiasm - physiopathology | Magnetic Resonance Imaging | Optic Neuritis - physiopathology | Visual Fields | Mumps - complications | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Hemianopsia - physiopathology | Optic Neuritis - pathology | Optic Chiasm - pathology | Methylprednisolone - administration & dosage | Parotitis - complications
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20. Full Text Role of the ipsilateral motor cortex in mirror movements
by Kanouchi, T and Yokota, T and Isa, F and Ishii, K and Senda, M
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 06/1997, Volume 62, Issue 6, pp. 629 - 632
The mechanism of mirror movements in two patients was investigated; one with congenital mirror movement, the other with schizencephaly. Transcranial magnetic... 
Mirror movement | Transcranial magnetic stimulation | Silent period | O-PET | PATHWAYS | SURGERY | (H2O)-O-15-PET | silent period | PSYCHIATRY | mirror movement | transcranial magnetic stimulation | CLINICAL NEUROLOGY | Motor Cortex - physiology | Humans | Adolescent | Dominance, Cerebral | Adult | Male | Electromyography | Tomography, Emission-Computed
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