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by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and ng, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian'an and Randall, Joshua C and Scherag, Ané and Vedantam, Sailaja and Wood, Anew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Daw, E. Warwick and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Frieich, Nele and Garcia, Melissa E and Gieaitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7538, pp. 187 - U378
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our... 
HUMAN HEIGHT | ABDOMINAL ADIPOSITY | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | SUSCEPTIBILITY LOCI | GLYCEMIC TRAITS | FALSE DISCOVERY | MESENCHYMAL STEM-CELLS | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Index Medicus | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article
by Estrada Gil, Karol and Styrkarsdottir, Unnur and Evangelou, Evangelos and Hsu, Yi-Hsiang and Duncan, Emma and Ntzani, Evangelia and Oei, Ling and Albagha, Omar M and Amin, Najaf and Kemp, John and Koller, Daniel and Li, Guo and Liu, Ching-Ti and Minster, Ryan and Moayyeri, Alireza and Vandenput, Liesbeth and Willner, Dana and Xiao, Su-Mei and Yerges-Armstrong, Laura and Zheng, Hou-Feng and Alonso, Nerea and Eriksson, Joel and Kammerer, Candace and Kaptoge, Stephen and Leo, Paul and Thorleifsson, Gudmar and Wilson, Scott and Wilson, James and Aalto, Ville and Alen, Theo and Aragaki, Aaron and Aspelund, Thor and Center, Jacqueline and Dailiana, Zoe and Duggan, C and Garcia, Melissa and Garcia-Giralt, Natàlia and Giroux, Sylvie and Hallmans, Göran and Hocking, Lynne and Husted, Lise Bjerre and Jameson, Karen and Khusainova, Rita and Kim, Ghi Su and Kooperberg, Charles and Koromila, Theodora and Kruk, Marcin and Laaksonen, Marika and LaCroix, Anea and Lee, Seung and Leung, Ping and Lewis, Joshua and Masi, Laura and Mencej-Beac, Simona and Nguyen, Tuan and Nogues, Xavier and Patel, Millan and Prezelj, Janez and Rose, Lynda and Scollen, Serena and Siggeirsdottir, Kristin and Smith, G.D and Svensson, Olle and Trompet, Stella and Trummer, Olivia and Schoor, Natasja and Woo, Margaret M and Zhu, Kun and Balcells, Susana and Brandi, M.L and Buckley, Brendan M and Cheng, Sulin and Christiansen, C and Cooper, Charles and Dedoussis, George and Ford, Ian and Frost, Morten and Goltzman, David and González-Macías, Jesús and Kähönen, Mika and Karlsson, Magnus and Khusnutdinova, Elza and Koh, Jung-Min and Kollia, Panagoula and Langdahl, Bente and Leslie, William and Lips, Paul and Ljunggren, Östen and Lorenc, Roman and Marc, Janja and Mellström, Dan and Obermayer-Pietsch, Barbara and Olmos, David and Pettersson-Kymmer, Ulrika and Reid, David and Riancho, José and Ridker, Paul and Rousseau, Francois and Lagboom, P Eline and Tang, Nelson L and ... and Medicinska fakulteten and Umeå universitet and Institutionen för folkhälsa och klinisk medicin and Institutionen för farmakologi och klinisk neurovetenskap and Klinisk farmakologi and Näringsforskning and Institutionen för kirurgisk och perioperativ vetenskap
Nature Genetics, ISSN 1061-4036, 05/2012, Volume 44, Issue 5, pp. 491 - 501
textabstractBone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and... 
WOMEN | POPULATION | IMPUTATION | VARIANTS | DISEASE | GENETICS & HEREDITY | OSTEOPOROTIC FRACTURES | GENE-EXPRESSION | LRP5 | PATTERNS | IMPUTED DATA | Glycoproteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Computational Biology | Intercellular Signaling Peptides and Proteins - genetics | European Continental Ancestry Group | Genotype | Male | Bone Density - genetics | Gene Expression Profiling | Phosphoproteins - genetics | Fractures, Bone - genetics | Mitochondrial Membrane Transport Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Female | Femur Neck - physiopathology | Osteoporosis - genetics | Spectrin - genetics | Quantitative Trait Loci | Lumbar Vertebrae - physiopathology | Quantitative trait loci | Measurement | Fractures | Bones | Genetic aspects | Identification and classification | Density | Risk factors | Medical research | Osteoporosis | Genomics | Bone density | Gene loci | Index Medicus | Vèrtebres lumbars | Gens | Femur | Genes | Bone densitometry | Densitometria òssia | Fèmur | Lumbar vertebrae | Basic Medicine | Medical Genetics | Medicinsk genetik | ortopedi | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | genetik | Genetics | Orthopaedics
Journal Article
by Moayyeri, A and Hsu, Y.H and Karasik, D and Estrada, K and Xiao, S.M and Nielson, C and Srikanth, P and Giroux, S and Wilson, S.G and Zheng, H.F and Smith, A.V and Pye, S.R and Leo, P.J and Teumer, A and Hwang, J.Y and Ohlsson, C and McGuigan, F and Minster, R.L and Hayward, C and Olmos, J.M and Lyytikainen, L.P and Lewis, J.R and Swart, K.M.A and Masi, L and Oldmeadow, C and Holliday, E.G and Cheng, S.L and van Schoor, N.M and Harvey, N.C and Kruk, M and Fabiola Del Greco, M and Igl, W and Trummer, O and Grigoriou, E and Luben, R and Liu, C.T and Zhou, Y.H and Oei, L and Medina-Gomez, C and Zmuda, J and Tranah, G and Brown, S.J and Williams, F.M and Soranzo, N and Jakobsdottir, J and Siggeirsdottir, K and Holliday, K.L and Hannemann, A and Go, M.J and Garcia, M and Polasek, O and Laaksonen, M and Zhu, K and Enneman, A.W and McEvoy, M and Peel, R and Sham, P.C and Jaworski, M and Johansson, A and Hicks, A.A and Pludowski, P and Scott, R and Dhonukshe-Rutten, R.A.M and van der Velde, N and Kahonen, M and Viikari, J.S and Sievanen, H and Raitakari, O.T and Gonzalez-Macias, J and Hernandez, J.L and Mellstroom, D and Ljunggren, O and Cho, Y.S and Volker, U and Nauck, M and Homuth, G and Volzke, H and Haring, R and Brown, M. A and McCloskey, E and Nicholson, G.C and Eastell, R and Eisman, J.A and Jones, G and Reid, I.R and Dennison, E.M and Wark, J and Boonen, S and Vanderschueren, D and Wu, F.C.W and Aspelund, T and Richards, J.B and Bauer, D and Hofman, A and Khaw, K.T and Dedoussis, G and Obermayer-Pietsch, B and Gyllensten, U and Pramstaller, P.P and Lorenc, R.S and ... and Institute of Medicine and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institutionen för medicin
Human Molecular Genetics, ISSN 0964-6906, 2014, Volume 23, Issue 11, pp. 3054 - 3068
Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by... 
FRACTURE | WOMEN | MINERAL DENSITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DENSITOMETRY | GENETICS & HEREDITY | X-RAY ABSORPTIOMETRY | RISK | QUANTITATIVE ULTRASOUND | PHENOTYPES | CALCANEUS | OSTEOPOROSIS | Index Medicus | Association Studies | Medicinsk genetik | Medical Genetics
Journal Article
BMJ (Online), ISSN 0959-8146, 2019, Volume 364, pp. l1042 - l1042
OBJECTIVE To investigate the shape of the causal relation between body mass index (BMI) and mortality. DESIGN Linear and non-linear mendelian randomisation... 
FAT | MEDICINE, GENERAL & INTERNAL | RISK | OBESITY | COHORT | BMI | Index Medicus | Abridged Index Medicus
Journal Article
by Oei, Ling and Hsu, Yi-Hsiang and Styrkarsdottir, Unnur and Eussen, Bert H and de Klein, Annelies and Peters, Marjolein J and Halldorsson, Bjarni and Liu, Ching-Ti and Alonso, Nerea and Kaptoge, Stephen K and Thorleifsson, Gudmar and Hallmans, Göran and Hocking, Lynne J and Husted, Lise Bjerre and Jameson, Karen A and Kruk, Marcin and Lewis, Joshua R and Patel, Millan S and Scollen, Serena and Svensson, Olle and Trompet, Stella and van Schoor, Natasja M and Zhu, Kun and Buckley, Brendan M and Cooper, Cyrus and Ford, Ian and Goltzman, David and González-Macías, Jesús and Langdahl, Bente Lomholt and Leslie, William D and Lips, Paul and Lorenc, Roman S and Olmos, José M and Pettersson-Kymmer, Ulrika and Reid, David M and Riancho, José A and Slagboom, P Eline and Garcia-Ibarbia, Carmen and Ingvarsson, Thorvaldur and Johannsdottir, Hrefna and Luben, Robert and Medina-Gómez, Carolina and Arp, Pascal and Nandakumar, Kannabiran and Palsson, Stefan Th and Sigurdsson, Gunnar and van Meurs, Joyce B J and Zhou, Yanhua and Hofman, Albert and Jukema, J Wouter and Pols, Huibert A P and Prince, Richard L and Cupples, L Adrienne and Marshall, Christian R and Pinto, Dalila and Sato, Daisuke and Scherer, Stephen W and Reeve, Jonathan and Thorsteinsdottir, Unnur and Karasik, David and Richards, J Brent and Stefansson, Kari and Uitterlinden, André G and Ralston, Stuart H and Ioannidis, John P A and Kiel, Douglas P and Rivadeneira, Fernando and Estrada, Karol and Medicinska fakulteten and Umeå universitet and Institutionen för folkhälsa och klinisk medicin and Institutionen för farmakologi och klinisk neurovetenskap and Ortopedi and Klinisk farmakologi and Enheten för biobanksforskning and Näringsforskning and Institutionen för kirurgisk och perioperativ vetenskap
Journal of Medical Genetics, ISSN 0022-2593, 02/2014, Volume 51, Issue 2, pp. 122 - 131
Journal Article