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Haematologica, ISSN 0390-6078, 12/2019, Volume 104, Issue 12, pp. 2330 - 2332
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 02/2018, Volume 141, Issue 2, pp. 522 - 524
Journal Article
Experimental Hematology, ISSN 0301-472X, 2017, Volume 50, pp. 13 - 21
Dysregulation of the mechanistic target of rapamycin complex 1 (mTORC1)-p70 ribosomal protein kinase 1 (S6K1) signaling pathway occurs frequently in acute... 
Hematology, Oncology and Palliative Medicine | Advanced Basic Science | MAMMALIAN TARGET | INITIATING CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | PHOSPHATIDYLINOSITOL 3-KINASE/AKT | GROWTH-CONTROL | TUMOR-SUPPRESSOR COMPLEX | REFRACTORY HEMATOLOGIC MALIGNANCIES | RAPAMYCIN INHIBITOR | DEFOROLIMUS AP23573 | HEMATOLOGY | P70 S6 KINASE | MTOR INHIBITOR | Hematopoietic Stem Cells - drug effects | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | TOR Serine-Threonine Kinases - metabolism | Leukemia, Myeloid, Acute - pathology | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myeloid, Acute - metabolism | Antineoplastic Agents - therapeutic use | Hematopoietic Stem Cells - metabolism | Enzyme Activation - drug effects | Hematopoiesis - drug effects | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Animals | Neoplastic Stem Cells - metabolism | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Physiological aspects | Medical colleges | Development and progression | Drug resistance | Hematopoietic stem cells | Medical research | Medicine, Experimental | Protein kinases | mTORC1 | Acute myeloid leukemia | Leukemia stem cells | S6K1
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/2017, Volume 214, Issue 12, pp. 3577 - 3596
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2019, Volume 129, Issue 12, pp. 5468 - 5473
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3754 - 3754
Heterozygous mutations in FLT3ITD, TET2 and DNMT3A are associated with human neoplasms. Whole exome sequencing of patients demonstrate co-occurrence of several... 
Journal Article
Cell Cycle, ISSN 1538-4101, 01/2013, Volume 12, Issue 1, pp. 7 - 8
Journal Article
Cell Cycle, ISSN 1538-4101, 01/2013, Volume 12, Issue 1, pp. 7 - 8
Journal Article
Cell Cycle, ISSN 1538-4101, 01/2013, Volume 12, Issue 1, pp. 7 - 8
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e90758
Journal Article
Current Stem Cell Reports, ISSN 2198-7866, 12/2016, Volume 2, Issue 4, pp. 368 - 378
Hematopoietic stem cells (HSC) are the most well-defined stem cell population and have provided invaluable understanding of tissue-specific stem cell... 
Life Sciences | Stem Cells | Self-renewal | Leukemia stem cells | PTEN | Akt | mTORC1 | Hematopoietic stem cells | Cell Biology
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 2623 - 2623
Abstract Juvenile myelomonocytic leukemia (JMML) is an aggressive childhood myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN). It has no effective... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1633 - 1633
Abstract Histone deacetylase inhibitors (HDACi) are being evaluated in several clinical trials for the treatment of hematological malignancies and 2 of them... 
Journal Article
Oncotarget, ISSN 1949-2553, 2012, Volume 3, Issue 9, pp. 909 - 910
Journal Article