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1. Full Text Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
by Liu, Mengzhen and Jiang, Yu and Wedow, Robbee and Li, Yue and Brazel, David M and Chen, Fang and Datta, Gargi and Davila-Velderrain, Jose and McGuire, Daniel and Tian, Chao and Zhan, Xiaowei and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Hinds, David A and Hromatka, Bethann S and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie A. M and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Pitts, Steven J and Mitchell, Amy and Skogholt, Anne Heidi and Winsvold, Bendik Slagsvold and Sivertsen, Børge and Stordal, Eystein and Morken, Gunnar and Kallestad, Håvard and Heuch, Ingrid and Zwart, John-Anker and Fjukstad, Katrine Kveli and Pedersen, Linda M and Gabrielsen, Maiken Elvestad and Johnsen, Marianne Bakke and Skrove, Marit and Indredavik, Marit Sæbø and Drange, Ole Kristian and Bjerkeset, Ottar and Børte, Sigrid and Stensland, Synne Øien and Choquet, Hélène and Docherty, Anna R and Faul, Jessica D and Foerster, Johanna R and Fritsche, Lars G and Gordon, Scott D and Haessler, Jeffrey and Hottenga, Jouke-Jan and Huang, Hongyan and Jang, Seon-Kyeong and Jansen, Philip R and Ling, Yueh and Mägi, Reedik and Matoba, Nana and McMahon, George and Mulas, Antonella and Orrù, Valeria and Palviainen, Teemu and Pandit, Anita and Reginsson, Gunnar W and Smith, Jennifer A and Taylor, Amy E and Turman, Constance and Willemsen, Gonneke and Young, Hannah and Young, Kendra A and Zajac, Gregory J. M and Zhao, Wei and Zhou, Wei and Bjornsdottir, Gyda and Boardman, Jason D and Boehnke, Michael and Boomsma, Dorret I and Chen, Chu and Cucca, Francesco and Davies, Gareth E and Eaton, Charles B and Ehringer, Marissa A and Esko, Tõnu and Fiorillo, Edoardo and Gillespie, Nathan A and Gudbjartsson, Daniel F and Haller, Toomas and Harris, Kathleen Mullan and Heath, Andrew C and Hewitt, John K and ... and HUNT All In Psychiat and 23 Me Res Team and 23andMe Research Team and HUNT All-In Psychiatry
Nature genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 237 - 244
Genetics | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Phenotype | Humans | Middle Aged | Female | Male | Risk | Smoking - genetics | Tobacco Use Disorder - genetics | Genetic Variation - genetics | Tobacco - adverse effects | Genome-Wide Association Study - methods | Alcohol Drinking - genetics | Usage | Analysis | Influence | Drinking of alcoholic beverages | Research | Health aspects | Causes and theories of causation | Risk factors | Diseases | Tobacco habit | Phenotypes | Dopamine | Genes | Health risks | Principal components analysis | Nervous system | Genomes | Loci | Alcohol use | Datasets | Substance use | Studies | Genetic variance | Signal transduction | Tobacco | Etiology | Alcoholic beverages | Glutamatergic transmission | Health risk assessment | Neurotransmission | Drug use | Dopamine receptors | Smoking | Index Medicus
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2. Full Text A meta-analysis of genome-wide association studies identifies multiple longevity genes
by Deelen, Joris and Evans, Daniel and Arking, Dan and Tesi, N and Nygaard, M and Liu, X and Wojczynski, Mary and Biggs, M and Spek, Ashley and Atzmon, Gil and Ware, Erin B and Sarnowski, C and Smith, Albert and Seppälä, Ilkka and Cordell, Heather and Dose, J and Amin, N and Arnold, Alice and Ayers, Kristin and Barzilai, Ari and Becker, E.J and Beekman, M and Blanché, Hélène and Christensen, Kaare and Christiansen, L and Collerton, Joanna and Cubaynes, S and Cummings, S and Davies, Karen and Debrabant, B and Deleuze, Jean-François and Duncan, R and Faul, J.D and Franceschi, Claudio and Galan, Pilar and Gudnason, V and Harris, Tamara and Huisman, Martijn and Hurme, Mikko and Jagger, Carol and Jansen, Iris and Jylhä, M and Kähönen, M and Karasik, David and Kardia, Sharon and Kingston, A and Kirkwood, John and Launer, Lenore and Lehtimäki, Terho and Lieb, Wolfgang and Lyytikäinen, L.-P and Martin-Ruiz, Carmen and Min, J and Nebel, Almut and Newman, Anne B and Nie, C and Nohr, Christian and Orwoll, Eric and Perls, Thomas T and Province, Mike and Psaty, B.M and Raitakari, Olli and Reinders, Marcel and Robine, Jean-Marie and Rotter, Jerome I and Sebastiani, Paola and Smith, Jennifer A and Sørensen, Thorkild and Taylor, Kent and Uitterlinden, Ané and Flier, Wiesje and Lee, Sven and Duijn, Cornelia and Heemst, Diana and Vaupel, James and Weir, D and Ye, K and Zeng, Y and Zheng, W and Holstege, Henne and Kiel, Douglas P and Lunetta, Kathryn and Slagboom, Eline and Murabito, Joanne
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 3669 - 14
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Heat-Shock Proteins - genetics | Genome-Wide Association Study | Apolipoprotein E4 - genetics | Longevity - genetics | Apolipoprotein E2 - genetics | Humans | Phenotypes | Apolipoprotein E | Genes | Association analysis | Genomes | Longevity | Gene expression | Survival | Age | Index Medicus | Life Sciences | Genetics
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3. Full Text A bivariate genome-wide approach to metabolic syndrome: STAMPEED Consortium
by Kraja, Aldi T and Vaidya, Dhananjay and Pankow, James S and Goodarzi, Mark O and Assimes, Themistocles L and Kullo, Iftikhar J and Sovio, Ulla and Mathias, Rasika A and Sun, Yan V and Franceschini, Nora and Absher, Devin and Li, Guo and Zhang, Qunyuan and Feitosa, Mary F and Glazer, Nicole L and Haritunians, Talin and Hartikainen, Anna-Liisa and Knowles, Joshua W and North, Kari E and Iribarren, Carlos and Kral, Brian and Yanek, Lisa and O'Reilly, Paul F and McCarthy, Mark I and Jaquish, Cashell and Couper, David J and Chakravarti, Aravinda and Psaty, Bruce M and Becker, Lewis C and Province, Michael A and Boerwinkle, Eric and Quertermous, Thomas and Palotie, Leena and Jarvelin, Marjo-Riitta and Becker, Diane M and Kardia, Sharon L. R and Rotter, Jerome I and Chen, Yii-Der Ida and Borecki, Ingrid B
Diabetes (New York, N.Y.), ISSN 0012-1797, 04/2011, Volume 60, Issue 4, pp. 1329 - 1339
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Diabetes. Impaired glucose tolerance | Miscellaneous | Other metabolic disorders | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Metabolic diseases | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Humans | Middle Aged | Genotype | Male | Phenotype | Metabolic Syndrome - genetics | Polymorphism, Single Nucleotide - genetics | Adult | Female | Aged | Complications and side effects | Genetic aspects | Research | Metabolic syndrome X | Genetic variation | Health aspects | Index Medicus | Abridged Index Medicus | Genetics
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4. Full Text The transcriptional landscape of age in human peripheral blood
by Peters, Marjolein and Joehanes, Roby and Pilling, Luke and Schurmann, Claudia and Conneely, Karen N and Powell, Joseph and Reinmaa, Eva and Sutphin, George L and Zhernakova, Alexana and Schramm, Katharina and Wilson, Yana A and Kobes, Sayuko and Tukiainen, Taru and Ramos, Yolande and Göring, Harald H and Fornage, Myriam and Liu, YongMei and Gharib, Sina and Stranger, Barbara and Jager, Philip and Aviv, Abraham and Levy, Daniel and Murabito, Joanne and Munson, Peter J and Huan, Tianxiao and Hofman, Albert and Uitterlinden, Ané and Rivadeneira Ramirez, Fernando and van Rooij, Jeroen and Stolk, Lisette and Broer, Linda and Verbiest, Michael and Jhamai, Mila and Arp, Pascal and Metspalu, Anes and Tserel, Liina and Milani, Lili and Samani, Nilesh and Peterson, Pärt and Kasela, Silva and Codd, Veryan and Peters, Annette and Ward-Caviness, Cavin K and Herder, Christian and Waldenberger, Melanie and Roden, Michael and Singmann, Paula and Zeilinger, Sonja and Illig, Thomas and Homuth, Georg and Grabe, Hans Jörgen and Völzke, Henry and Steil, Leif and Kocher, Thomas and Murray, Anna and Melzer, David and Yaghootkar, Hanieh and Bandinelli, S and Moses, Eric and Kent, Jack and Curran, Joanne and Johnson, Matthew and Williams-Blangero, Sarah and Westra, Harm-Jan and McRae, Allan F and Smith, Jennifer A and Kardia, Sharon and Hovatta, Iiris and Perola, Markus and Ripatti, Samuli and Salomaa, Veikko and Henders, Anjali and Martin, Nicholas and Smith, Alicia K and Mehta, Divya and Binder, Elisabeth B and Nylocks, K. Maria and Kennedy, Elizabeth M and Klengel, Torsten and Ding, Jingzhong and Suchy-Dicey, Astrid and Enquobahrie, D and Brody, Jennifer A and Rotter, Jerome I and Chen, Yii-Der I and Houwing-Duistermaat, Jeanine and Kloppenburg, Margreet and Slagboom, Eline and Helmer, Quinta and Hollander, Wouter and Bean, Shannon and Raj, Towfique and Bakhshi, Noman and Wang, Qiao Ping and Oyston, Lisa J and Psaty, Bruce and Tracy, Russell and Montgomery, Grant and Turner, Stephen and Blangero, John and ... and NABEC UKBEC Consortium and NABEC/UKBEC Consortium
Nature communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, pp. 8570 - 8570
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Aging - blood | DNA Methylation | Humans | Transcriptome | European Continental Ancestry Group | Gene Expression Profiling | Biomarkers - blood | Index Medicus
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5. Full Text A Statistical Approach for Testing Cross-Phenotype Effects of Rare Variants
by Broadaway, K. Alaine and Cutler, David J and Duncan, Richard and Moore, Jacob L and Ware, Erin B and Jhun, Min A and Bielak, Lawrence F and Zhao, Wei and Smith, Jennifer A and Peyser, Patricia A and Kardia, Sharon L.R and Ghosh, Debashis and Epstein, Michael P
American journal of human genetics, ISSN 0002-9297, 03/2016, Volume 98, Issue 3, pp. 525 - 540
complex human traits | pleiotropy | rare variant | gene mapping | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Blood Pressure | Body Mass Index | Multivariate Analysis | Genetic Association Studies | Oligonucleotide Array Sequence Analysis | Humans | Databases, Genetic | Genotype | Exome | Genetic Variation | Phenotype | Cardiovascular System - metabolism | Cholesterol, HDL - blood | Models, Genetic | Genome, Human | Usage | Genetic variation | Genetic research | Statistical methods | Research | Methods | Observations | Genotype & phenotype | Genomes | Biological variation | Epidemiology | Index Medicus
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6. Full Text Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci
by Liu, C and Kraja, Aldi and Smith, Jennifer A and Brody, Jennifer A and Franceschini, Nora and Bis, Joshua and Rice, Kenneth and Morrison, Alanna and Lu, Yingchang and Weiss, S and Guo, Xiuqing and Palmas, Walter and Martin, Lisa and Chen, Y and Surenan, P and nos, Fotios and Cook, J.P and Auer, Paul and Chu, Auey and Giri, A and Zhao, W and Jakobsdottir, Margret and Lin, L.-A and Stafford, Jeanette M and Amin, Najaf and Mei, H and Yao, Jiefen and Voorman, Jeanine and Larson, Martin and Grove, Megan and Smith, Albert Vernon and Hwang, S.J and Chen, Han and Huan, Tianxiao and Kosova, G and Stitziel, Nathan and Kathiresan, Sekar and Samani, Nilesh and Schunkert, Heribert and Deloukas, Panagiotis and Li, Man and Fuchsberger, Christian and Pattaro, Cristian and Gorski, Mathias and Kooperberg, Charles and Papanicolaou, George and Rossouw, J.E and Faul, Jessica D and Kardia, Sharon and Bouchard, Claude and Raffel, Leslie and Uitterlinden, A.G and Franco, Oscar and Vasan, Ramachanan and O'Donnell, Christopher and Taylor, Kent and Liu, K.Y and Bottinger, Erwin and Gottesman, Rebecca and Daw, E. Warwick and Giulianini, Franco and Ganesh, Santhi and Salfati, Elias and Harris, Tamara and Launer, L.J and Dörr, Marcus and Felix, Stephan and Rettig, Rainer and Völzke, Henry and Kim, Eric and Lee, Wen-Jane and Lee, I.T and Sheu, W.H.-H and Tsosie, K.S and Edwards, D.R.V and Liu, YongMei and Correa, A and Weir, David and Völker, Uwe and Ridker, Paul and Boerwinkle, Eric and Gudnason, Vilmundur and Reiner, Alexander and Van Duijn, C.M and Borecki, Ingrid and Edwards, Todd L and Chakravarti, Aravinda and Rotter, J.I and Psaty, Bruce and Loos, Ruth and Fornage, Myriam and Ehret, Georg and Newton-Cheh, Christopher and Levy, Daniel and Chasman, Daniel and Myocardial Infarction Genetics CAR and GOT2Dgenes Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and CKDGen Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia and CHD Exome+ Consortium and GoT2DGenes Consortium and T2D-GENES Consortium
Nature genetics, ISSN 1061-4036, 10/2016, Volume 48, Issue 10, pp. 1162 - 1170
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Exome | Genetic Variation | Genome-Wide Association Study | Oligonucleotide Array Sequence Analysis | Blood Pressure - genetics | Humans | Genotype | Polymorphism, Single Nucleotide | Hypertension - genetics | Genome, Human | Studies | Proteins | Genealogy | Databases | Cardiovascular disease | Blood pressure | Genomes | Metabolism | Meta-analysis | Index Medicus
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