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British Journal of Pharmacology, ISSN 0007-1188, 2018
There has been a revolution within clinical trials to include females in the research pipeline. However, there has been limited change in the preclinical... 
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 03/2019, Volume 35, Issue 20, pp. 4196 - 4199
In many areas of biological research, hypotheses are tested in a sequential manner, without having access to future p-values or even the number of hypotheses... 
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 08/2007, Volume 6, Issue 8, pp. 1354 - 1364
Journal Article
PROTEOMICS, ISSN 1615-9853, 09/2007, Volume 7, Issue S1, pp. 42 - 50
Quantitative proteomics is the comparison of distinct proteomes which enables the identification of protein species which exhibit changes in expression or... 
Genetic Variation | Multivariate Analysis | Validation Studies as Topic | Analysis of Variance | Proteomics - methods | Random Allocation | Research Design
Journal Article
PLoS Biology, ISSN 1544-9173, 03/2018, Volume 16, Issue 3, p. e2005413
Journal Article
Disease models & mechanisms, ISSN 1754-8403, 10/2018, Volume 11, Issue 11, p. dmm036160
The high attrition rate of preclinical agents entering oncology clinical trials has been associated with poor understanding of the heterogeneous patient... 
Preclinical trial | Patient-derived tumor xenografts | Population studies | MODELS | CANCER XENOGRAFTS | PATHOLOGY | CELL BIOLOGY | Resource | 304
Journal Article
Journal of Pharmacological and Toxicological Methods, ISSN 1056-8719, 07/2019, Volume 98, p. 106591
Evaluation of the effects of candidate drugs on the nervous system in preclinical safety pharmacology studies utilises a global neurobehavioral assessment,... 
ICH S7A | Rat | Irwin test | Safety pharmacology | Functional observational battery | Core battery | NERVOUS-SYSTEM | BACLOFEN | MORPHINE | BEHAVIOR | RECEPTOR | NEUROTOXICITY | BUSPIRONE | GABA-A | PHARMACOLOGY & PHARMACY | TOXICOLOGY | BRAIN
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 09/2010, Volume 9, Issue 9, pp. 1885 - 1897
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e114872
Journal Article
Cell, ISSN 0092-8674, 07/2013, Volume 154, Issue 2, p. 452
Mutations in whole organisms are powerful ways of interrogating gene function in a realistic context. We describe a program, the Sanger Institute Mouse... 
Journal Article
by White, Gemma and White, Jacqueline K and Gerdin, Anna-Karin and Karp, Natasha A and Ryder, Ed and Buljan, Marija and Bussell, James N and Salisbury, Jennifer and Clare, Simon and Ingham, Neil J and Podrini, Christine and Houghton, Richard and Estabel, Jeanne and Bottomley, Joanna R and Melvin, David G and Sunter, David and Adams, David J and Adams, Niels C and Baker, Lauren and Barnes, Caroline and Beveridge, Ryan and Cambridge, Emma and Carragher, Damian and Chana, Prabhjoat and Clarke, Kay and Hooks, Yvette and Igosheva, Natalia and Ismail, Ozama and Jackson, Hannah and Kane, Leanne and Lacey, Rosalind and Lafont, David Tino and Lucas, Mark and Maguire, Simon and McGill, Katherine and McIntyre, Rebecca E and Messager, Sophie and Mottram, Lynda and Mulderrig, Lee and Pearson, Laila and Pearson, Selina and Protheroe, Hayley J and Roberson, Laura-Anne and Salsbury, Grace and Sanderson, Mark and Sanger, Daniel and Shannon, Carl and Thompson, Paul C and Tuck, Elizabeth and Vancollie, Valerie E and Brackenbury, Lisa and Bushell, Wendy and Cook, Ross and Dalvi, Priya and Gleeson, Diane and Habib, Bishoy and Hardy, Matt and Liakath-Ali, Kifayathullah and Miklejewska, Evelina and Price, Stacey and Sethi, Debarati and Trenchard, Elizabeth and von Schiller, Dominique and Vyas, Sapna and West, Anthony P and Woodward, John and Wynn, Elizabeth and Evans, Arthur and Gannon, David and Griffiths, Mark and Holroyd, Simon and Iyer, Vivek and Kipp, Christian and Lewis, Morag and Li, Wei and Oakley, Darren and Richardson, David and Smedley, Damian and Agu, Chukwuma and Bryant, Jackie and Delaney, Liz and Gueorguieva, Nadia I and Tharagonnet, Helen and Townsend, Anne J and Biggs, Daniel and Brown, Terry and Brown, Ellen and Collinson, Adam and Dumeau, Charles-Etienne and Grau, Evelyn and Harrison, James and Harrison, Sarah and Ingle, Catherine E and Kundi, Helen and Madich, Alla and Mayhew, Danielle and Metcalf, Tom and Newman, Stuart and Pass, Johanna and Reynolds, Helen and ... and Sanger Inst Mouse Genetics Project and Sanger Institute Mouse Genetics Project
Cell, ISSN 0092-8674, 07/2013, Volume 154, Issue 2, pp. 452 - 464
Journal Article