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PLoS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6, p. e0131670
Glioblastoma multiforme (GBM) is the most common primary brain tumor and among the most difficult to treat malignancies per se. In almost 90% of all GBM... 
MALIGNANT GLIOMA | GLIOMA-CELL LINES | APOPTOSIS | PROTEIN | 3-KINASE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DUAL INHIBITOR | DIFFERENTIATION | CANCER | TEMOZOLOMIDE | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Furans - pharmacology | Humans | Brain Neoplasms - pathology | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Brain Neoplasms - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Pyrimidines - pharmacology | Brain Neoplasms - drug therapy | Drug Synergism | Cell Movement - drug effects | Signal Transduction - drug effects | Glioblastoma - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Glioblastoma - drug therapy | Neoplasm Staging | Chemotherapy | Health aspects | Glioblastoma multiforme | Analysis | Apoptosis | Cancer | TOR protein | Cell proliferation | Brain | Pediatrics | Cell culture | Biotechnology | Brain tumors | Brain cancer | Glioblastoma | AKT protein | Neurosurgery | Neuroblastoma | Kinases | Cancer therapies | Proteins | Penicillin | Cell cycle | Therapeutic applications | Data processing | Pharmacology | Seniority | Gene expression | 1-Phosphatidylinositol 3-kinase | Medicine | Signaling | Inhibitors | Cell lines | Stem cells
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi40 - vi40
Abstract Histone deacetylase inhibition is a potential new strategy for the treatment of glioblastoma (GBM) and FDA-approved for multiple myeloma. However,... 
Abstracts
Journal Article
Oncotarget, ISSN 1949-2553, 11/2018, Volume 9, Issue 87, pp. 35719 - 35720
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi213 - vi213
Journal Article
Aging, ISSN 1945-4589, 2016, Volume 8, Issue 9, pp. 1830 - 1831
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 1, pp. 1 - 2
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1067 - 14
Journal Article
World Neurosurgery, ISSN 1878-8750, 07/2019
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13, pp. 3513 - 3526
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi96 - vi96
Abstract OBJECTIVE Repurposing represents a promising approach to safely accelerate the clinical application of therapeutics with anti-cancer activity. In this... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi94 - vi94
Abstract OBJECTIVE Drug repurposing is a strategy to safely accelerate the clinical application of therapeutics that provide anti-cancer activity. CUSP9... 
Abstracts
Journal Article
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi36 - vi36
Abstract The receptor kinase, c-MET, has emerged as a target for glioblastoma therapy. However, treatment resistance evolves inevitably. By performing a global... 
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi90 - vi90
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi98 - vi99
Abstract The purpose of this study is to improve the efficacy of imipridones, a novel class of AKT/ERK inhibitors. The lead compound ONC201 has entered... 
Abstracts
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi21 - vi21
Abstract BACKGROUND Despite refinements of neurosurgical techniques and emerging adjuvant therapies, patients with recurrent glioblastoma continue to face a... 
Abstracts
Journal Article
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