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by Wain, Louise V and Shrine, Nick R. G and Artigas, Maria Soler and Erzurumluoglu, A Mesut and Noyvert, Boris and Bossini-Castillo, Lara and Obeidat, Ma'en and Henrys, Amanda P and Portelli, Michael A and Hall, Robert J and Billington, Charlotte K and Rimington, Tracy L and Fenech, Anthony G and John, Catherine and Blake, Tineka and Jackson, Victoria E and Allen, Richard J and Prins, Bram P and Campbell, Archie and Porteous, David J and Jarvelin, Marjo-Riitta and Wielscher, Matthias and Jamess, Alan L and Hui, Jennie and Wareham, Nicholas J and Zhao, Jing Hua and Wilson, James F and Joshi, Peter K and Stubbe, Beate and Rawal, Rajesh and Schulz, Holger and Imboden, Medea and Probst-Hensch, Nicole M and Karrasch, Stefan and Gieger, Christian and Deary, Ian J and Harris, Sarah E and Marten, Jonathan and Rudan, Igor and Enroth, Stefan and Gyllensten, Ulf and Kerr, Shona M and Polasek, Ozren and Kahonen, Mika and Surakka, Ida and Vitart, Veronique and Hayward, Caroline and Lehtimaki, Terho and Raitakari, Olli T and Evans, David M and Henderson, A. John and Pennell, Craig E and Wang, Carol A and Sly, Peter D and Wan, Emily S and Busch, Robert and Hobbs, Brian D and Litonjua, Augusto and Sparrow, David W and Gulsvik, Amund and Bakke, Per S and Crapo, James D and Beaty, Terri H and Hansel, Nadia N and Mathias, Rasika A and Ruczinski, Ingo and Barnes, Kathleen C and Bosse, Yohan and Joubert, Philippe and van den Berge, Maarten and Brandsma, Corry-Anke and Pare, Peter D and Sin, Don and Nickle, David C and Hao, Ke and Gottesman, Omri and Dewey, Frederick E and Bruse, Shannon E and Carey, David J and Kirchner, H Lester and Jonsson, Stefan and Thorleifsson, Gudmar and Jonsdottir, Ingileif and Gislason, Thorarinn and Stefansson, Kari and Schurmann, Claudia and Nadkarni, Girish N and Bottinger, Erwin P and Loos, Ruth J. F and Walters, Robin G and Chen, Zhengming and Millwood, Iona Y and Vaucher, Julien and Kurmi, Om P and Li, Liming and Hansell, Anna L and Brightling, Chris and Zeggini, Eleftheria and Cho, Michael H and Silverman, Edwin K and ... and Geisinger-Regeneron DiscovEHR and Understanding Soc Sci Grp and Understanding Society Scientific Group and Geisinger-Regeneron DiscovEHR Collaboration and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 03/2017, Volume 49, Issue 3, pp. 416 - 425
Journal Article
by Shrine, Nick and Guyatt, Anna L and Erzurumluoglu, A. Mesut and Jackson, Victoria E and Hobbs, Brian D and Melbourne, Carl A and Batini, Chiara and Fawcett, Katherine A and Song, Kijoung and Sakornsakolpat, Phuwanat and Li, Xingnan and Boxall, Ruth and Reeve, Nicola F and Obeidat, Ma’en and Zhao, Jing Hua and Wielscher, Matthias and Weiss, Stefan and Kentistou, Katherine A and Cook, James P and Sun, Benjamin B and Zhou, Jian and Hui, Jennie and Karrasch, Stefan and Imboden, Medea and Harris, Sarah E and Marten, Jonathan and Enroth, Stefan and Kerr, Shona M and Surakka, Ida and Vitart, Veronique and Lehtimäki, Terho and Allen, Richard J and Bakke, Per S and Beaty, Terri H and Bleecker, Eugene R and Bossé, Yohan and Brandsma, Corry-Anke and Chen, Zhengming and Crapo, James D and Danesh, John and DeMeo, Dawn L and Dudbridge, Frank and Ewert, Ralf and Gieger, Christian and Gulsvik, Amund and Hansell, Anna L and Hao, Ke and Hoffman, Joshua D and Hokanson, John E and Homuth, Georg and Joshi, Peter K and Joubert, Philippe and Langenberg, Claudia and Li, Xuan and Li, Liming and Lin, Kuang and Lind, Lars and Locantore, Nicholas and Luan, Jian’an and Mahajan, Anubha and Maranville, Joseph C and Murray, Alison and Nickle, David C and Packer, Richard and Parker, Margaret M and Paynton, Megan L and Porteous, David J and Prokopenko, Dmitry and Qiao, Dandi and Rawal, Rajesh and Runz, Heiko and Sayers, Ian and Sin, Don D and Smith, Blair H and Soler Artigas, María and Sparrow, David and Tal-Singer, Ruth and Timmers, Paul R. H. J and Van den Berge, Maarten and Whittaker, John C and Woodruff, Prescott G and Yerges-Armstrong, Laura M and Troyanskaya, Olga G and Raitakari, Olli T and Kähönen, Mika and Polašek, Ozren and Gyllensten, Ulf and Rudan, Igor and Deary, Ian J and Probst-Hensch, Nicole M and Schulz, Holger and James, Alan L and Wilson, James F and Stubbe, Beate and Zeggini, Eleftheria and Jarvelin, Marjo-Riitta and Wareham, Nick and Silverman, Edwin K and Hayward, Caroline and Morris, Andrew P and ... and Understanding Soc Sci Grp and Understanding Society Scientific Group
Nature Genetics, ISSN 1061-4036, 03/2019, Volume 51, Issue 3, pp. 481 - 493
Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive pulmonary disease (COPD). In a genome-wide association study in... 
GWAS | VARIANTS | GENETICS & HEREDITY | LOCI | HERITABILITY | GENOME-WIDE ASSOCIATION | COPD | Respiratory function | Lung | Lung diseases | Genomes | Gene expression | Studies | Consortia | Pathways | Obstructive lung disease | New combinations | Quality control | Chronic obstructive pulmonary disease | Health risk assessment | Smoking | Index Medicus
Journal Article
by Loth, Daan and Artigas, M.S and Gharib, Sina and Wain, Louise and Franceschini, Nora and Koch, Beate and Pottinger, Tess and Smith, G.D and Duan, Qing and Oldmeadow, Christopher and Lee, Mi Kyeong and Strachan, David and James, Alan and Huffman, Jennifer and Vitart, Veronique and Ramasamy, Adaikalavan and Wareham, Nick and Kaprio, Jaakko and Wang, Xin-Qun and Trochet, Holly and Kähönen, Mika and Flexeder, Claudia and Albrecht, Eva and Lopez, Lorna and Thyagarajan, Bharat and Alves, Alexessander Couto and Enroth, Stefan and Omenaas, Ernst and Joshi, Peter and Fall, Magnus and Viñuela, Ana and Launer, Lenore and Loehr, Laura and Fornage, Myriam and Li, Guo and Wilk, Jemma and Tang, Wenbo and Manichaikul, Ani and Lahousse, Lies and Harris, Tamara and North, Kari and Rudnicka, Alicja and Hui, Jennie and Gu, Xiangjun and Lumley, Thomas and Wright, Alan and Hastie, Nick and Campbell, Susan and Kumar, Rajesh and Pin, Isabelle and Scott, Robert and Pietilainen, Kirsi Hannele and Surakka, Ida and Liu, Yongmei and Holliday, Elizabeth and Schulz, Holger and Heinrich, Joachim and Davies, Gail and Vonk, Judith and Wojczynski, Mary and Pouta, Anneli and Johansson, Åsa and Wild, Sarah and Ingelsson, Erik and Rivadeneira Ramirez, Fernando and Völzke, Henry and Hysi, Pirro and Eiriksdottir, Gudny and Morrison, Alanna and Rotter, Jerome and Gao, Wei and Postma, Dirkje and White, Wendy and Rich, Stephen and Hofman, Albert and Aspelund, Thor and Couper, David and Smith, Lewis and Psaty, Bruce and Lohman, Kurt and Burchard, Esteban and Uitterlinden, Ané and Garcia, Melissa and Joubert, Bonnie and McArdle, Wendy and Musk, Arthur and Hansel, Christian and Heckbert, Susan and Zgaga, Lina and Meurs, Joyce and Navarro, Pau and Rudan, Igor and Oh, Yeon-Mok and Redline, Susan and Jarvis, Deborah and Zhao, Jing Hua and Rantanen, Taina and O'Connor, George and Ripatti, Samuli and Scott, Rodney and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Uppsala kliniska forskningscentrum (UCR)
Nature Genetics, ISSN 1061-4036, 01/2014, Volume 46, Issue 7, pp. 669 - 677
Journal Article
by Artigas, Maria Soler and Wain, Louise V and Miller, Suzanne and Kheirallah, Abdul Kader and Huffman, Jennifer E and Ntalla, Ioanna and Shrine, Nick and Obeidat, Ma'en and Trochet, Holly and McArdle, Wendy L and Alves, Alexessander Couto and Hui, Jennie and Zhao, Jing Hua and Joshi, Peter K and Teumer, Alexander and Albrecht, Eva and Imboden, Medea and Rawal, Rajesh and Lopez, Lorna M and Marten, Jonathan and Enroth, Stefan and Surakka, Ida and Polasek, Ozren and Lyytikainen, Leo-Pekka and Granell, Raquel and Hysi, Pirro G and Flexeder, Claudia and Mahajan, Anubha and Beilby, John and Bosse, Yohan and Brandsma, Corry-Anke and Campbell, Harry and Gieger, Christian and Glaeser, Sven and Gonzalez, Juan R and Grallert, Harald and Hammond, Chris J and Harris, Sarah E and Hartikainen, Anna-Liisa and Heliovaara, Markku and Henderson, John and Hocking, Lynne and Horikoshi, Momoko and Hutri-Kahonen, Nina and Ingelsson, Erik and Johansson, Asa and Kemp, John P and Kolcic, Ivana and Kumar, Ashish and Lind, Lars and Melen, Erik and Musk, Arthur W and Navarro, Pau and Nickle, David C and Padmanabhan, Sandosh and Raitakari, Olli T and Ried, Janina S and Ripatti, Samuli and Schulz, Holger and Scott, Robert A and Sin, Don D and Starr, John M and Vinuela, Ana and Voelzke, Henry and Wild, Sarah H and Wright, Alan F and Zemunik, Tatijana and Jarvis, Deborah L and Spector, Tim D and Evans, David M and Lehtimaki, Terho and Vitart, Veronique and Kahonen, Mika and Gyllensten, Ulf and Rudan, Igor and Deary, Ian J and Karrasch, Stefan and Probst-Hensch, Nicole M and Heinrich, Joachim and Stubbe, Beate and Wilson, James F and Wareham, Nicholas J and James, Alan L and Morris, Anew P and Jarvelin, Marjo-Riitta and Hayward, Caroline and Sayers, Ian and Strachan, David P and Hall, Ian P and Tobin, Martin D and Deloukas, Panos and Hansell, Anna L and Hubbard, Richard and Jackson, Victoria E and Marchini, Jonathan and Pavord, Ian and Thomson, Neil C and Zeggini, Eleftheria and UK BiLEVE and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Medicinsk genetik och genomik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Uppsala kliniska forskningscentrum (UCR)
Nature Communications, ISSN 2041-1723, 12/2015, Volume 6, Issue 1, pp. 8658 - 8658
Journal Article
BMC Pulmonary Medicine, ISSN 1471-2466, 02/2018, Volume 18, Issue 1, pp. 27 - 27
Background: The relationship of spirometric values to other respiratory and functional parameters in advanced age is not well studied. We assessed this... 
Spirometry | Body plethysmography | Diffusing capacity | STANDARDIZATION | BODYPLETHYSMOGRAPHY | LUNG-FUNCTION | EQUATIONS | REFERENCE VALUES | HEALTHY-ADULTS | CARBON-MONOXIDE | RECOMMENDATIONS | RESPIRATORY SYSTEM | OBSTRUCTION | Usage | Lung diseases | Aged | Diagnosis | Light-emitting diodes | Health aspects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0177501 - e0177501
Although hyperlipidemia is common in COPD, its relationship to comorbidities, risk factors and lung function in COPD has not been studied in detail. Using the... 
DIFFUSING-CAPACITY | DIABETES-MELLITUS | MORTALITY | OBSTRUCTIVE PULMONARY-DISEASE | METABOLIC SYNDROME | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | BODY-MASS INDEX | HEALTH | CORONARY-HEART-DISEASE | REFERENCE VALUES | Pulmonary Disease, Chronic Obstructive - diagnosis | Lung - pathology | Comorbidity | Humans | Middle Aged | Risk Factors | Male | Lung - physiopathology | Pulmonary Disease, Chronic Obstructive - physiopathology | Pulmonary Disease, Chronic Obstructive - complications | Pulmonary Disease, Chronic Obstructive - epidemiology | Forced Expiratory Volume | Hyperlipidemias - epidemiology | Vital Capacity | Hyperlipidemias - etiology | Biomarkers | Female | Aged | Respiratory Function Tests | Cohort Studies | Lung diseases, Obstructive | Hyperlipidemia | Analysis | Pulmonary function tests | Research | Risk factors | Heart | Intensive care | Critical care | Cardiovascular disease | Metabolic syndrome | Epidemiology | Respiratory tract | Consortia | Body mass index | Ethics | Health economics | Ischemia | Consent | Chronic obstructive pulmonary disease | Carbon monoxide | Heart diseases | Hypertension | Gold | Internal medicine | Mortality | Diabetes mellitus | Environmental health | Health risks | Regression analysis | Risk analysis | Patients | Coronary artery disease | Medicine | Studies | Hospitals | Diabetes | Smoking | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2017, Volume 49, Issue 12, pp. 1752 - 1757
Journal Article