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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 37, pp. E5399 - E5407
Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5⁺) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Intestinal stem cell | Niche | Lgr5 | Deep crypt secretory cells | Reg4 | niche | intestinal stem cell | deep crypt secretory cells | HOMEOSTASIS | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | GOBLET CELLS | INTESTINAL CRYPTS | PANETH CELLS | DIFFERENTIATION | REG-IV | EXPRESSION | ADENOMAS | Proteins | Homeostasis | Amino acids | Digestive system | Stem cells | Biological Sciences | PNAS Plus
Journal Article
Cell, ISSN 0092-8674, 04/2015, Volume 161, Issue 3, pp. 674 - 690
Modulation of protein function is used to intervene in cellular processes but is often done indirectly by means of introducing DNA or mRNA encoding the... 
STEM-CELLS | IN-VITRO | HOST FACTORS | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | MEDIATED DELIVERY | LYSIS | TRANSDUCTION | GENOME | PATHOGENS | CELL BIOLOGY | Proteins | Gene Targeting | Transduction, Genetic | RNA | Humans | Cells, Cultured | Cytological Techniques | Embryonic Stem Cells | Medical colleges | Molecular genetics
Journal Article
Nature Protocols, ISSN 1754-2189, 02/2016, Volume 11, Issue 2, pp. 347 - 58
This protocol describes a strategy for the generation of 3D prostate organoid cultures from healthy mouse and human prostate cells (either bulk or FACS-sorted... 
PROGENITOR CELLS | MURINE PROSTATE | STEM-CELLS | IN-VITRO | VIVO | REGENERATION | EXPANSION | BIOCHEMICAL RESEARCH METHODS | Epithelial Cells - physiology | Organ Culture Techniques - methods | Animals | Organoids - growth & development | Humans | Cells, Cultured | Culture Media, Serum-Free | Male | Mice | Time | Prostate - physiology | Cell culture | Care and treatment | Prostate cancer | Methods
Journal Article
Science, ISSN 0036-8075, 01/2017, Volume 355, Issue 6320, pp. 84 - 88
Journal Article
Cell, ISSN 0092-8674, 09/2014, Volume 159, Issue 1, pp. 176 - 187
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2404 - 10
Journal Article
Nature Methods, ISSN 1548-7091, 01/2012, Volume 9, Issue 1, pp. 81 - 83
he study of gene function in endodermal epithelia such as of stomach, small intestine and colon relies heavily on transgenic approaches. Establishing such... 
STEM-CELLS | IN-VITRO | COLON | INHIBITION | MOUSE GENOME | BIOCHEMICAL RESEARCH METHODS | Physiological aspects | MicroRNA | Research | Gene expression | Mammals | Cell culture | Molecular biology | Stem cells
Journal Article
Nature, ISSN 0028-0836, 09/2014, Volume 513, Issue 7518, pp. 422 - 5
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2019, Volume 111, Issue 3, pp. 221 - 223
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 976 - 976
Journal Article