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1. Full Text Activity and safety of ODM-201 in patients with progressive metastatic castration-resistant prostate cancer (ARADES): an open-label phase 1 dose-escalation and randomised phase 2 dose expansion trial
by Fizazi, Karim, Prof and Massard, Christophe, MD and Bono, Petri, MD and Jones, Robert, MD and Kataja, Vesa, Prof and James, Nicholas, Prof and Garcia, Jorge A, MD and Protheroe, Andrew, MD and Tammela, Teuvo L, Prof and Elliott, Tony, MD and Mattila, Leena, MD and Aspegren, John, MSc and Vuorela, Annamari, PhD and Langmuir, Peter, MD and Mustonen, Mika, PhD and for the ARADES study group and ARADES Study Grp and ARADES study group
The lancet oncology, ISSN 1470-2045, 2014, Volume 15, Issue 9, pp. 975 - 985
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Confidence Intervals | Prognosis | Humans | Middle Aged | Male | Androgen Receptor Antagonists - pharmacology | Prostatic Neoplasms, Castration-Resistant - pathology | Patient Selection | Dose-Response Relationship, Drug | Neoplasm Metastasis | Neoplasm Invasiveness - pathology | Patient Safety | Pyrazoles - pharmacology | Drug Administration Schedule | Administration, Oral | Kaplan-Meier Estimate | Survival Rate | Treatment Outcome | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostate-Specific Antigen - blood | Disease-Free Survival | Maximum Tolerated Dose | Aged | Prostatic Neoplasms, Castration-Resistant - mortality | Neoplasm Staging | Prostate cancer | Care and treatment | Metastasis | Index Medicus
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2. Full Text Transcription factors zeb1, twist and snai1 in breast carcinoma
by Soini, Ylermi and Tuhkanen, Hanna and Sironen, Reijo and Virtanen, Ismo and Kataja, Vesa and Auvinen, Päivi and Mannermaa, Arto and Kosma, Veli-Matti
BMC cancer, ISSN 1471-2407, 02/2011, Volume 11, Issue 1, pp. 73 - 73
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Prognosis | Stromal Cells - pathology | Epithelial-Mesenchymal Transition - physiology | Homeodomain Proteins - metabolism | Humans | Carcinoma - mortality | Breast Neoplasms - metabolism | Female | Carcinoma - pathology | Snail Family Transcription Factors | Transcription Factors - physiology | Stromal Cells - metabolism | Carcinoma - diagnosis | Nuclear Proteins - metabolism | Transcription Factors - metabolism | Breast Neoplasms - pathology | Twist-Related Protein 1 - physiology | Survival Analysis | Breast Neoplasms - mortality | Breast Neoplasms - diagnosis | Nuclear Proteins - physiology | Carcinoma - metabolism | Homeodomain Proteins - physiology | Neoplasm Staging | Twist-Related Protein 1 - metabolism | Zinc Finger E-box-Binding Homeobox 1 | Transcription factors | Physiological aspects | Development and progression | Breast cancer | Genetic aspects | Research | Oncogenes | Index Medicus
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3. Full Text Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
by Michailidou, Kyriaki and Beesley, Jonathan and Lindstrom, Stephen and Canisius, Sander and Dennis, Joe and Lush, Michael and Maranian, Melanie and Bolla, Manjeet and Wang, Qing and Shah, Mitul and Perkins, Barbara and Czene, Kamila and Eriksson, Mikael and Darabi, Hatef and Brand, Judith S and Bojesen, Stig and Nordestgaard, Børge and Flyger, Henrik and Nielsen, Sune and Rahman, Nazneen and Turnbull, Clare and Fletcher, Olivia and Peto, Julian and Gibson, Lorna and Santos Silva, Isabel and Chang-Claude, Jenny and Flesch-Janys, Dieter and Rudolph, Anja and Eilber, Ursula and Behrens, Timothy and Nevanlinna, Heli and Muranen, Taru and Aittomäki, Kristiina and Blomqvist, Carl and Khan, Sofia and Aaltonen, Kirsimari and Ahsan, Habibul and Kibriya, Muhammad and Whittemore, Alice S and John, Esther M and Malone, Kathleen E and Gammon, Marilie and Santella, Regina M and Ursin, Giske and Makalic, Enes and Schmidt, Daniel and Casey, Graham and Hunter, David J and Gapstur, Susan M and Gaudet, Mia and Diver, Ryan and Haiman, Christopher A and Schumacher, Freick and Henderson, Brian and Le Marchand, Loic and Berg, Christine and Chanock, Stephen and Figueroa, Jonine and Hoover, Robert N and Lambrechts, Diether and Neven, Patrick and Wildiers, Hans and Limbergen, Erik and Schmidt, Marjanka and Broeks, Annegien and Verhoef, S and Cornelissen, Sten and Couch, Fergus and Olson, Janet and Hallberg, Boubou and Vachon, Celine and Waisfisz, Quinten and Meijers-Heijboer, Hanne and Adank, Muriel and Luijt, Rob and Li, Jingmei and Liu, Jianjun and Humphreys, Manjeet and Kang, Daehee and Choi, Ji-Yeob and Park, Sue K and Yoo, K.Y and Matsuo, Keitaro and Ito, Hidemi and Iwata, Hiroji and Tajima, Kazuo and Guénel, Pascal and Truong, Thérèse and Mulot, Claire and Sanchez, Marie and Burwinkel, Barbara and Marme, Federick and Surowy, Harald and Sohn, Christof and Wu, Anna H and Tseng, Chiu-chen and Van Den Berg, David and Stram, Daniel O and González-Neira, Anna and Benítez, Javier and ... and KConFab Investigators and AOCS Grp and BOCS and NBCS and GENICA Network and kConFab Investigators and AOCS Group
Nature genetics, ISSN 1061-4036, 04/2015, Volume 47, Issue 4, pp. 373 - 380
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Breast Neoplasms - genetics | Microarray Analysis | Humans | Female | Polymorphism, Single Nucleotide | Genetic Loci | Case-Control Studies | Cohort Studies | Quantitative trait loci | Genetic susceptibility | Genetic research | Breast cancer | Genetic aspects | Research | Identification and classification | Risk factors | Studies | Datasets | Genealogy | Disease | Womens health | Genes | Genomes | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Fluorouracil, Epirubicin, and Cyclophosphamide With Either Docetaxel or Vinorelbine, With or Without Trastuzumab, As Adjuvant Treatments of Breast Cancer: Final Results of the FinHer Trial
by Heikki Joensuu and Petri Bono and Vesa Kataja and Tuomo Alanko and Riitta Kokko and Raija Asola and Tapio Utriainen and Taina Turpeenniemi-Hujanen and Sirkku Jyrkkiö and Kari Möykkynen and Leena Helle and Seija Ingalsuo and Marjo Pajunen and Mauri Huusko and Tapio Salminen and Päivi Auvinen and Hannu Leinonen and Mika Leinonen and Jorma Isola and Pirkko-Liisa Kellokumpu-Lehtinen
Journal of clinical oncology, ISSN 0732-183X, 12/2009, Volume 27, Issue 34, pp. 5685 - 5692
Life Sciences & Biomedicine | Oncology | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | Medical sciences | Tumors | Breast Neoplasms - surgery | Cyclophosphamide - administration & dosage | Humans | Middle Aged | Epirubicin - administration & dosage | Vinblastine - administration & dosage | Antibodies, Monoclonal, Humanized | Breast Neoplasms - chemistry | Vinblastine - analogs & derivatives | Adult | Female | Chemotherapy, Adjuvant | Neoplasm Recurrence, Local | Survival Rate | Lymphatic Metastasis | Breast Neoplasms - drug therapy | Disease-Free Survival | Taxoids - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Breast Neoplasms - mortality | Aged | Receptor, ErbB-2 - analysis | Trastuzumab | Index Medicus
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5. Full Text Incidence of subsequent primary cancers and radiation-induced subsequent primary cancers after low dose-rate brachytherapy monotherapy for prostate cancer in long-term follow-up
by Vuolukka, Kristiina and Auvinen, Päivi and Palmgren, Jan-Erik and Aaltomaa, Sirpa and Kataja, Vesa
BMC cancer, ISSN 1471-2407, 05/2020, Volume 20, Issue 1, pp. 453 - 453
Care and treatment | Radioisotope brachytherapy | Mortality | Colorectal cancer | Health aspects | Prostate cancer | Risk factors | Cancer | Index Medicus | Radiation induced subsequent primary cancer | Subsequent primary cancer | Low dose-rate brachytherapy
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6. Full Text Surgical specimen can be replaced by core samples in assessment of ER, PR and HER-2 for invasive breast cancer
by Sutela, Anna and Vanninen, Ritva and Sudah, Mazen and Berg, Marja and Kiviniemi, Vesa and Rummukainen, Jaana and Kataja, Vesa and Kärjä, Vesa
Acta oncologica, ISSN 0284-186X, 2008, Volume 47, Issue 1, pp. 38 - 46
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Biopsy, Needle - instrumentation | Breast Neoplasms - surgery | Biomarkers, Tumor - analysis | Neoplasm Invasiveness | Humans | Middle Aged | Receptors, Estrogen - analysis | Biopsy, Needle - methods | Receptors, Progesterone - analysis | Breast Neoplasms - chemistry | In Situ Hybridization | Breast Neoplasms - pathology | Aged, 80 and over | Adult | Female | Aged | Receptor, ErbB-2 - analysis | Research Design | Index Medicus
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7. Full Text Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
by Bojesen, Stig E and Pooley, Karen A and Johnatty, Sharon E and Beesley, Jonathan and Michailidou, Kyriaki and Tyrer, Jonathan P and Edwards, Stacey L and Pickett, Hilda A and Shen, Howard C and Smart, Chanel E and Hillman, Kristine M and Mai, Phuong L and Lawrenson, Kate and Stutz, Michael D and Lu, Yi and Karevan, Rod and Woods, Nicholas and Johnston, Rebecca L and French, Juliet D and Chen, Xiaoqing and Weischer, Maren and Nielsen, Sune F and Maranian, Melanie J and Ghoussaini, Maya and Ahmed, Shahana and Baynes, Caroline and Bolla, Manjeet K and Wang, Qin and Dennis, Joe and McGuffog, Lesley and Barrowdale, Daniel and Lee, Anew and Healey, Sue and Lush, Michael and Tessier, Daniel C and Vincent, Daniel and Bacot, Françis and Vergote, Ignace and Lambrechts, Sanina and Despierre, Evelyn and Risch, Harvey A and González-Neira, Anna and Rossing, Mary Anne and Pita, Guillermo and Doherty, Jennifer A and Alvarez, Nuria and Larson, Melissa C and Fridley, Brooke L and Schoof, Nils and Chang-Claude, Jenny and Cicek, Mine S and Peto, Julian and Kalli, Kimberly R and Broeks, Annegien and Armasu, Sebastian M and Schmidt, Marjanka K and Braaf, Linde M and Winterhoff, Boris and Nevanlinna, Heli and Konecny, Gottfried E and Lambrechts, Diether and Rogmann, Lisa and Guénel, Pascal and Teoman, Attila and Milne, Roger L and Garcia, Joaquin J and Cox, Angela and Shridhar, Vijayalakshmi and Burwinkel, Barbara and Marme, Frederik and Hein, Rebecca and Sawyer, Elinor J and Haiman, Christopher A and Wang-Gohrke, Shan and Anulis, Irene L and Moysich, Kirsten B and Hopper, John L and Odunsi, Kunle and Lindblom, Annika and Giles, Graham G and Brenner, Hermann and Simard, Jacques and Lurie, Galina and Fasching, Peter A and Carney, Michael E and Radice, Paolo and Wilkens, Lynne R and Swerdlow, Anthony and Goodman, Marc T and Brauch, Hiltrud and Garcia-Closas, Montserrat and Hillemanns, Peter and Winqvist, Robert and Dürst, Matthias and Devilee, Peter and Runnebaum, Ingo and Jakubowska, Anna and Lubinski, Jan and Mannermaa, Arto and Butzow, Ralf and ... and Gene Environm Interactimi Breast and Kathleen Cuningham Fdn Consortium and Australian Ovarian Canc Study and Epidemiological Study BRCA1 and Hereditary Breast Ovarian Canc Res and Genetic Modifiers Canc Risk BRCA1 and Australian Canc Study and Swedish Breast Canc Study SWE-BRCA and Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers (GEMO) and Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) and Gene Environment Interaction and Breast Cancer (GENICA) and Swedish Breast Cancer Study (SWE-BRCA) and Epidemiological study of BRCA1 & BRCA2 Mutation Carriers (EMBRACE) and Australian Ovarian Cancer Study and Australian Cancer Study and Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab) and The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON)
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 4, pp. 371 - 384
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Luciferases - metabolism | Alternative Splicing | Oligonucleotide Array Sequence Analysis | Humans | Breast Neoplasms - etiology | Genetic Loci - genetics | Ovarian Neoplasms - pathology | Gene Expression Profiling | Case-Control Studies | DNA Methylation | Telomerase - genetics | Female | Ovarian Neoplasms - etiology | Real-Time Polymerase Chain Reaction | Telomere - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | RNA, Messenger - genetics | Risk Factors | Genotype | Reverse Transcriptase Polymerase Chain Reaction | Breast Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Biomarkers, Tumor - genetics | Chromatin - genetics | Breast cancer | Genetic aspects | Research | Single nucleotide polymorphisms | Risk factors | Ovarian cancer | Genetics | Mutation | Index Medicus | Càncer de mama | Càncer d'ovari | Telòmer | Telomere | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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8. Full Text Genome-wide association studies identify four ER negative-specific breast cancer risk loci
by Garcia-Closas, Montserrat and Couch, Fergus J and Lindstrom, Sara and Michailidou, Kyriaki and Schmidt, Marjanka K and Brook, Mark N and Orr, Nick and Rhie, Suhn Kyong and Riboli, Elio and Feigelson, Heather S and Le Marchand, Loic and Buring, Julie E and Eccles, Diana and Miron, Penelope and Fasching, Peter A and Brauch, Hiltrud and Chang-Claude, Jenny and Carpenter, Jane and Godwin, Anew K and Nevanlinna, Heli and Giles, Graham G and Cox, Angela and Hopper, John L and Bolla, Manjeet K and Wang, Qin and Dennis, Joe and Dicks, Ed and Howat, Will J and Schoof, Nils and Bojesen, Stig E and Lambrechts, Diether and Broeks, Annegien and Anulis, Irene L and Guénel, Pascal and Burwinkel, Barbara and Sawyer, Elinor J and Hollestelle, Antoinette and Fletcher, Olivia and Winqvist, Robert and Brenner, Hermann and Mannermaa, Arto and Hamann, Ute and Meindl, Alfons and Lindblom, Annika and Zheng, Wei and Devillee, Peter and Goldberg, Mark S and Lubinski, Jan and Kristensen, Vessela and Swerdlow, Anthony and Anton-Culver, Hoda and Dörk, Thilo and Muir, Kenneth and Matsuo, Keitaro and Wu, Anna H and Radice, Paolo and teo, Soo Hwang and Shu, Xiao-Ou and Blot, William and Kang, Daehee and Hartman, Mikael and Sangrajrang, Suleeporn and Shen, Chen-Yang and Southey, Melissa C and Park, Daniel J and Hammet, Fleur and Stone, Jennifer and Veer, Laura J. Van't and Rutgers, Emiel J and Lophatananon, Artitaya and Stewart-Brown, Sarah and Siriwanarangsan, Pornthep and Peto, Julian and Schrauder, Michael G and Ekici, Arif B and Beckmann, Matthias W and dos Santos Silva, Isabel and Johnson, Nichola and Warren, Helen and Tomlinson, Ian and Kerin, Michael J and Miller, Nicola and Marme, Federick and Schneeweiss, Aneas and Sohn, Christof and Truong, Therese and Laurent-Puig, Pierre and Kerbrat, Pierre and Nordestgaard, Børge G and Nielsen, Sune F and Flyger, Henrik and Milne, Roger L and Perez, Jose Ignacio Arias and Menéndez, Primitiva and Müller, Heiko and Arndt, Volker and Stegmaier, Christa and Lichtner, Peter and Lochmann, Magdalena and Justenhoven, Christina and ... and KConFab Investigators and Gene ENvironm Interaction Breast and Familial Breast Canc Study FBCS and Australian Breast Canc Tissue Bank and kConFab Investigators and Familial Breast Cancer Study (FBCS) and Australian Breast Cancer Tissue Bank (ABCTB) Investigators and Gene ENvironmental Interaction and breast CAncer (GENICA) Network and The Gene ENvironmental Interaction and breast CAncer (GENICA) Network
Nature genetics, ISSN 1061-4036, 2013, Volume 45, Issue 4, pp. 392 - 398
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Receptors, Estrogen - metabolism | Receptors, Estrogen - genetics | Oligonucleotide Array Sequence Analysis | Humans | Risk Factors | Breast Neoplasms - etiology | Genetic Loci - genetics | Cooperative Behavior | Genotype | Case-Control Studies | Breast Neoplasms - metabolism | Breast Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Female | Quantitative trait loci | Receptors | Estrogen | Physiological aspects | Breast cancer | Genetic aspects | Research | Identification and classification | Health aspects | Risk factors | Confidence intervals | Genealogy | Womens health | Cell cycle | African Americans | Genetics | Genomes | Family medical history | Tumors | Index Medicus | Medicin och hälsovetenskap
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9. Full Text ST14 gene variant and decreased matriptase protein expression predict poor breast cancer survival
by Kauppinen, Jaana M and Kosma, Veli-Matti and Soini, Ylermi and Sironen, Reijo and Nissinen, Minna and Nykopp, Timo K and Kärjä, Vesa and Eskelinen, Matti and Kataja, Vesa and Mannermaa, Arto
Cancer epidemiology, biomarkers & prevention, ISSN 1055-9965, 09/2010, Volume 19, Issue 9, pp. 2133 - 2142
Oncology | Public, Environmental & Occupational Health | Life Sciences & Biomedicine | Science & Technology | Gynecology. Andrology. Obstetrics | Mammary gland diseases | Biological and medical sciences | Medical sciences | Tumors | Immunohistochemistry | Multivariate Analysis | Gene Expression | Prognosis | Serine Endopeptidases - biosynthesis | Humans | Proteinase Inhibitory Proteins, Secretory - genetics | Genotype | Survival Rate | Proteinase Inhibitory Proteins, Secretory - biosynthesis | Case-Control Studies | Breast Neoplasms - metabolism | Genetic Variation | Breast Neoplasms - enzymology | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Alleles | Serine Endopeptidases - genetics | Female | Polymorphism, Single Nucleotide | Serine Endopeptidases - metabolism | Index Medicus
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