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Nature Chemical Biology, ISSN 1552-4450, 02/2018, Volume 14, Issue 2, pp. 126 - 134
Development of biased ligands targeting G protein-coupled receptors (GPCRs) is a promising approach for current drug discovery. Although structure-based drug... 
DOPAMINE-RECEPTOR | PROTEIN-COUPLED RECEPTOR | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SEROTONIN RECEPTORS | FUNCTIONAL SELECTIVITY | MOLECULAR-DYNAMICS SIMULATIONS | DRUG TARGETS | MU-OPIOID RECEPTOR | BETA-ADRENERGIC RECEPTOR | AGONIST
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 02/2018, Volume 14, Issue 2, p. 126
Development of biased ligands targeting G protein-coupled receptors (GPCRs) is a promising approach for current drug discovery. Although structure-based drug... 
Design | Residues | Signaling | Receptors | G protein-coupled receptors | Amino acids | Ligands | Arrestin | Drug discovery | Drug development | Crystal structure
Journal Article
mBio, ISSN 2161-2129, 03/2016, Volume 7, Issue 2, p. e01986
Human cytomegalovirus (HCMV), a betaherpesvirus, persists indefinitely in the human host through poorly understood mechanisms. The UL136 gene is carried within... 
MICROBIOLOGY | PROTEIN ISOFORMS | INFECTION | ENDOTHELIAL-CELLS | GENES | Cell Line | Animals | Protein Isoforms - metabolism | Virus Replication | Models, Biological | Virus Latency | Humans | Cytomegalovirus Infections - virology | Mice | Cytomegalovirus - physiology | Viral Proteins - metabolism | Disease Models, Animal
Journal Article
by Marcogliese, Paul C and Shashi, Vandana and Spillmann, Rebecca C and Stong, Nicholas and Rosenfeld, Jill A and Koenig, Mary Kay and Martínez-Agosto, Julian A and Martínez-Agosto, Julián A and Herzog, Matthew and Herzog, Matthew R and Chen, Agnes H and Chen, Shan and Dickson, Patricia I and Lin, Henry J and Vera, Moin U and Salamon, Noriko and Ortiz, Damara and Infante, Elena and Steyaert, Wouter and Dermaut, Bart and Poppe, Bruce and Chung, Hyung-Lok and Zuo, Zhongyuan and Lee, Hane and Lee, Brendan H and Lee, Brendan and Lee, Pei-Tseng and Kanca, Oguz and Xia, Fan and Yang, Yaping and Smith, Kevin S and Smith, Edward C and Jasien, Joan and Kansagra, Sujay and Spiridigliozzi, Gail and El-Dairi, Mays and Lark, Robert and Riley, Kacie and Koeberl, Dwight D and Golden-Grant, Katie and Callens, Steven and Coucke, Paul and Hemelsoet, Dimitri and Terryn, Wim and Van Coster, Rudy and Adams, David R and Alejandro, Mercedes E and Allard, Patrick and Azamian, Mahshid S and Bacino, Carlos A and Balasubramanyam, Ashok and Barseghyan, Hayk and Batzli, Gabriel F and Beggs, Alan H and Behnam, Babak and Bican, Anna and Bick, David P and Birch, Camille L and Bonner, Devon and Boone, Braden E and Bostwick, Bret L and Briere, Lauren C and Brown, Donna M and Brush, Matthew and Burke, Elizabeth A and Burrage, Lindsay C and Clark, Gary D and Coakley, Terra R and Cogan, Joy D and Cooper, Cynthia M and Cope, Heidi and Craigen, William J and D’Souza, Precilla and Davids, Mariska and Dayal, Jyoti G and Dell’Angelica, Esteban C and Dhar, Shweta U and Dillon, Ani and Dipple, Katrina M and Donnell-Fink, Laurel A and Dorrani, Naghmeh and Dorset, Daniel C and Douine, Emilie D and Draper, David D and Eckstein, David J and Emrick, Lisa T and Eng, Christine M and Eskin, Ascia and Esteves, Cecilia and Estwick, Tyra and Ferreira, Carlos and Fogel, Brent L and Friedman, Noah D and Gahl, William A and Glanton, Emily and Godfrey, Rena A and Goldstein, David B and Gould, Sarah E and Gourdine, Jean-Philippe F and Groden, Catherine A and ... and Undiagnosed Dis Network and Program Undiagnosed Dis UD-PrOZA and Program for Undiagnosed Diseases (UD-PrOZA) and Undiagnosed Diseases Network
The American Journal of Human Genetics, ISSN 0002-9297, 08/2018, Volume 103, Issue 2, pp. 245 - 260
Interferon regulatory factor 2 binding protein-like ( ) encodes a member of the IRF2BP family of transcriptional regulators. Currently the biological function... 
CG11138 | ataxia | Drosophila | neurodegeneration | seizures | C3HC4 RING finger | developmental regression | pits | EAP1 | hypotonia | RECURRENT DE-NOVO | TRANSGENESIS | PROTEIN | UNDIAGNOSED DISEASES NETWORK | GENE | GENETICS & HEREDITY | ADRENOLEUKODYSTROPHY | MUTATIONS | EXPRESSION | DROSOPHILA | Physiological aspects | Nervous system | Development and progression | Genetic aspects | Degeneration | Research | Binding proteins
Journal Article
International Journal of Cell Biology, ISSN 1687-8876, 2012, Volume 2012, pp. 208014 - 11
Selective autophagy is a process whereby specific targeted cargo proteins, aggregates, or organelles are sequestered into double-membrane-bound phagophores... 
Proteins | Cellular biology | Cloning | Biosynthesis | Kinases | Gene expression | Autophagy
Journal Article
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