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Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A13170 - A13170
IntroductionCardiovascular risk factors are associated with a higher incidence of developing Alzheimer’s disease. A common feature of these risk factors is... 
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 2019, p. 271678X18822474
Cerebral amyloid angiopathy (CAA) is present in over half of the elderly population and in 80-90% of Alzheimer's disease (AD) patients. CAA is defined by the... 
cerebrovascular | ADAM10 | endothelial nitric oxide synthase | beta amyloid | cerebral amyloid angiopathy
Journal Article
Hypertension, ISSN 0194-911X, 09/2018, Volume 72, Issue Suppl_1
Journal Article
Circulation Research, ISSN 0009-7330, 09/2016, Volume 119, Issue 10, pp. 1128 - 1134
RATIONALE:Alzheimer’s disease (AD) has an unknown etiology; however, cardiovascular risk factors are associated with a higher incidence of AD. A defining... 
tau | Endothelial nitric oxide synthase | cerebrovascular disease | Cdk5 | Alzheimer’s disease
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A12279 - A12279
Amyloid precursor protein (APP) is expressed in endothelium but vascular functions of this protein remain poorly understood. In endothelial cells, α-secretase... 
Journal Article
Circulation Journal, ISSN 1346-9843, 2016
In the central nervous system endothelial nitric oxide (NO) is an essential molecule responsible for the preservation of the functional integrity of the... 
BACE1 | Cerebral amyloid angiopathy | Alzheimer’s disease | Amyloid precursor protein | Hippocampus
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 06/2019, Volume 316, Issue 6, pp. H1297 - H1308
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 05/2012, Volume 23, Issue 5, pp. 781 - 784
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 19, pp. 7505 - 7510
Crosstalk between the brain and systemic responses in blood is increasingly suspected of playing critical roles in stroke. However, how this communication... 
Anger | Receptors | Astrocytes | Small interfering RNA | Brain ischemia | Antibodies | Strokes | Progenitor cells | Renovations | Endothelial cells | Vascular repair | Reactive glia | Brain remodeling | reactive glia | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | MECHANISMS | HMGB1 | vascular repair | TRAUMATIC BRAIN-INJURY | NEURITE OUTGROWTH | INFLAMMATION | NEUROGENESIS | brain remodeling | END-PRODUCTS RAGE | ISCHEMIC-STROKE | Immunohistochemistry | Interleukin-1beta - pharmacology | Humans | Brain Ischemia - genetics | Brain Ischemia - metabolism | Culture Media, Conditioned - pharmacology | Male | Stem Cells - cytology | Cerebral Infarction - genetics | Stem Cells - metabolism | Stroke - physiopathology | HMGB1 Protein - genetics | Recovery of Function | Stroke - genetics | Cerebral Infarction - physiopathology | Cerebral Infarction - metabolism | HMGB1 Protein - pharmacology | RNA Interference | Time Factors | HMGB1 Protein - metabolism | Disease Models, Animal | Animals, Newborn | Astrocytes - cytology | Astrocytes - drug effects | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Rats | Brain Ischemia - physiopathology | Rats, Sprague-Dawley | Blotting, Western | Stroke - metabolism | Animals | Endothelial Cells - cytology | Stem Cells - drug effects | Cell Proliferation - drug effects | Mice | Astrocytes - metabolism | Endothelial Cells - drug effects | Stroke (Disease) | Physiological aspects | Research | Endothelium | Biological Sciences
Journal Article
Aging, ISSN 1945-4589, 01/2018, Volume 10, Issue 1, pp. 100 - 114
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 08/2017, Volume 28, Issue 8, pp. 2253 - 2255
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 6/2019, Volume 39, Issue 6, pp. 1085 - 1098
The mechanisms underlying dysfunction of cerebral microvasculature induced by type 1 diabetes (T1D) are not fully understood. We hypothesized that in cerebral... 
streptozotocin | cerebral microvessels | amyloid precursor protein | mice | A disintegrin and metalloprotease 10
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 12/2016, Volume 27, Issue 12, pp. 3508 - 3510
Journal Article
Journal Article