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SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3617 - 10
CPX-351 is a liposomally encapsulated 5:1 molar ratio of cytarabine and daunorubicin that recently received regulatory approval for the treatment of... 
CELLS | AML BLASTS | DNA | MULTIDISCIPLINARY SCIENCES | ACUTE MYELOGENOUS LEUKEMIA | ACUTE MYELOID-LEUKEMIA | MOLAR RATIO | COMPLEX KARYOTYPE | PHASE-I | MOLECULAR PATHWAYS | ATR | Myeloid leukemia | p53 Protein | CHK1 protein | DNA damage | Cytotoxicity | Myelodysplasia | Regulatory approval | DNA biosynthesis | Cytarabine | Daunorubicin | Anthracycline | Cell lines | Cell cycle | Acute myeloid leukemia | Apoptosis
Journal Article
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 18, Issue 1, pp. 75 - 87
Summary Background Poly(ADP-ribose) polymerase (PARP) inhibitors have activity in ovarian carcinomas with homologous recombination deficiency. Along with BRCA1... 
Hematology, Oncology and Palliative Medicine | BRCA MUTATION | POLY(ADP-RIBOSE) POLYMERASE | RANDOMIZED PHASE-2 | ONCOLOGY | HOMOLOGOUS RECOMBINATION DEFICIENCY | MUTANT-CELLS | PROSTATE-CANCER | INHIBITORS | DNA-REPAIR | NEGATIVE BREAST-CANCER | GENOMIC LOSS | Prognosis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Ovarian Neoplasms - pathology | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Germ-Line Mutation - genetics | Neoplasm Recurrence, Local - pathology | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Peritoneal Neoplasms - drug therapy | Fallopian Tube Neoplasms - genetics | Female | Antineoplastic Agents - pharmacology | Poly(ADP-ribose) Polymerases - chemistry | Ovarian Neoplasms - drug therapy | Platinum - pharmacology | Fallopian Tube Neoplasms - drug therapy | Peritoneal Neoplasms - pathology | Neoplasms, Glandular and Epithelial - pathology | Fallopian Tube Neoplasms - pathology | Survival Rate | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | BRCA1 Protein - genetics | International Agencies | Peritoneal Neoplasms - genetics | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Indoles - therapeutic use | Neoplasm Recurrence, Local - genetics | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Drug Resistance, Neoplasm - drug effects | Sugars | Monosaccharides | Ovarian cancer | Analysis | Carcinoma | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 8, pp. 3406 - 3411
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 3479 - 3479
Journal Article
ISSN 1477-0520, 4/2016, Volume 14, Issue 17, pp. 413 - 419
The topoisomerase (topo) I-DNA covalent complex represents an attractive target for developing diagnostic antibodies to measure responsiveness to drugs. We... 
Journal Article
by Kondrashova, Olga and Topp, Monique and Nesic, Ksenija and Lieschke, Elizabeth and Ho, Gwo-Yaw and Harrell, Maria I and Zapparoli, Giada V and Hadley, Alison and Holian, Robert and Boehm, Emma and Heong, Valerie and Sanij, Elaine and Pearson, Richard B and Krais, John J and Johnson, Neil and McNally, Orla and Ananda, Sumitra and Alsop, Kathryn and Hutt, Karla J and Kaufmann, Scott H and Lin, Kevin K and Harding, Thomas C and Traficante, Nadia and Chenevix-Trench, G and Green, A and Webb, P and Gertig, D and Fereday, S and Moore, S and Hung, J and Harrap, K and Sadkowsky, T and Pandeya, N and Malt, M and Mellon, A and Robertson, R and Vanden Bergh, T and Jones, M and Mackenzie, P and Maidens, J and Nattress, K and Chiew, Y.E and Stenlake, A and Sullivan, H and Alexander, B and Ashover, P and Brown, S and Corrish, T and Green, L and Jackman, L and Ferguson, K and Martin, K and Martyn, A and Ranieri, B and White, J and Jayde, V and Mamers, P and Bowes, L and Galletta, L and Giles, D and Hendley, J and Schmidt, T and Shirley, H and Ball, C and Young, C and Viduka, S and Tran, H and Bilic, S and Glavinas, L and Brooks, J and Stuart-Harris, R and Kirsten, F and Rutovitz, J and Clingan, P and Glasgow, A and Proietto, A and Braye, S and Otton, G and Shannon, J and Bonaventura, T and Stewart, J and Begbie, S and Friedlander, M and Bell, D and Baron-Hay, S and Ferrier, A and Gard, G and Nevell, D and Pavlakis, N and Valmadre, S and Young, B and Camaris, C and Crouch, R and Edwards, L and Hacker, N and Marsden, D and Robertson, G and Beale, P and Beith, J and Carter, J and ... and Australian Ovarian Cancer Study (AOCS)
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3970 - 16
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 06/2014, Volume 115, Issue 6, pp. 1128 - 1137
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 09/2017, Volume 7, Issue 9, pp. 984 - 998
Journal Article