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PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27265
Background: Scopolamine is a well-known cholinergic antagonist that causes amnesia in human and animal models. Scopolamine-induced amnesia in rodent models has... 
MEMORY | PROMOTERS | MULTIDISCIPLINARY SCIENCES | GROWTH | INVOLVEMENT | GENE-EXPRESSION | INDUCED AMNESIA | BDNF GENE | RECEPTORS | MESSENGER-RNA LEVELS | BACOPA-MONNIERA | DNA Damage - drug effects | Plant Leaves - chemistry | Cell Line | Triterpenes - pharmacology | Plant Extracts - pharmacology | Brain - drug effects | Brain - metabolism | Glial Fibrillary Acidic Protein | Nerve Tissue Proteins - metabolism | Scopolamine - toxicity | Animals | Cell Line, Tumor | Brain-Derived Neurotrophic Factor - metabolism | Mice | Oxidative Stress - drug effects | Withania - chemistry | Brain | Nervous system diseases | Scopolamine | Gliomas | Neurons | Analysis | Medicine, Botanic | Medicine, Herbal | Health aspects | Oxidative stress | Animal models | Acetylcholine receptors (muscarinic) | Laboratories | Toxicity | Memory | Zoology | Brain tumors | DNA damage | Science | Plasticity (glial) | Cytotoxicity | Biochemistry | Recovery | Neuronal-glial interactions | Proteins | Plasticity (behavioral) | Leaves | Receptors | Rodents | Glioma cells | Biocompatibility | Amnesia | Parks & recreation areas | Deoxyribonucleic acid--DNA | GAP-43 protein | Neurodegenerative diseases | Glial fibrillary acidic protein | Markers | Pharmacology | Apolipoproteins | Chemical compounds | Studies | Brain-derived neurotrophic factor | Molecular modelling | Neural networks | Pharmacy | Postsynaptic density proteins | Molecular biology | Alzheimers disease | Cancer | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 10, p. e13536
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37080
Glutamate neurotoxicity has been implicated in stroke, head trauma, multiple sclerosis and neurodegenerative disorders. Search for herbal remedies that may... 
ADHESION MOLECULE EXPRESSION | NERVOUS-SYSTEM | NEURITE OUTGROWTH | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | D-ASPARTATE RECEPTORS | NMDA RECEPTOR ACTIVATION | INDIAN GINSENG | TRANSCRIPTIONAL REGULATION | POLYSIALIC ACID | INDUCED NEUROPROTECTION | Neurons - pathology | Plant Extracts - pharmacology | Humans | Plant Leaves | Glial Fibrillary Acidic Protein - metabolism | Matrix Metalloproteinase 9 - metabolism | Neuroprotective Agents - pharmacology | Nerve Degeneration - prevention & control | Neurons - metabolism | Cell Death - drug effects | Neurons - drug effects | Tretinoin - pharmacology | Cell Line | Matrix Metalloproteinase 2 - metabolism | Withania | Rats | Neurotoxins - toxicity | Excitatory Amino Acid Antagonists - isolation & purification | Excitatory Amino Acid Antagonists - pharmacology | HSP70 Heat-Shock Proteins - metabolism | Animals | Neuroprotective Agents - isolation & purification | Cell Differentiation - drug effects | Neural Cell Adhesion Molecules - metabolism | Glutamic Acid - toxicity | Neurofilament Proteins - metabolism | Neurotoxins - antagonists & inhibitors | Plants, Medicinal | Nervous system diseases | Multiple sclerosis | Head injuries | Neural networks | Cell death | Analysis | Medicine, Botanic | Heat shock proteins | Amino acids | Medicine, Herbal | Glutamate | Health aspects | Neuroprotection | Toxicity | Brain tumors | Homeostasis | Ashes | Neuronal-glial interactions | Cell adhesion & migration | Cell adhesion molecules | Plasticity (neural) | Antioxidants | Leaves | Histograms | Neurotoxicity | Ischemia | Neurodegeneration | Rodents | Cell adhesion | Pretreatment | Neurological disorders | Stroke | Head | Neural cell adhesion molecule | Free radicals | Neurodegenerative diseases | Hsp70 protein | Pharmacology | Cell differentiation | Trauma | Chemical compounds | Studies | Herbal medicine | Phytochemicals | Brain research | Acids | Glioma | Excitotoxicity | Ginseng | Potassium | Herbal remedies | Retinoic acid | Apoptosis
Journal Article
09/2017, ISBN 3319591916, 507
Rapidly increasing ageing population and environmental stressors are the two main global concerns of increasing incidence of a variety of pathologies in the... 
Health Promotion and Disease Prevention | Medical Education | Biomedicine | Popular Science in Medicine and Health | Complementary & Alternative Medicine | Biomedicine general | Withania somnifera
eBook
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 17344 - 11
Journal Article
BMC Research Notes, ISSN 1756-0500, 06/2018, Volume 11, Issue 1, pp. 403 - 7
Short-term viability assays of cultured cells in 96-well plates are routinely used to determine the cytotoxicity or safety of drugs. These are often based on... 
Clonogenicity | Crystal violet | Quantitative-qualitative assay | QCV | Cell Line | Biological Assay | Animals | Signal Transduction | Cell Survival | Cell Count | Chemotherapy | Usage | Research | Morphology | Cancer cells | Cancer | Drugs | Short term | Medical research | Cell culture | Laboratories | Color | Cytology | Cytotoxicity | Cancer therapies | Cell density | Mammalian cells | Plant extracts | Microscopy | Quantitative–qualitative assay
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0152017 - e0152017
Helicteres angustifolia L. is a shrub that forms a common ingredient of several cancer treatment recipes in traditional medicine system both in China and Laos.... 
CANCER-CELLS | METASTASIS | ASHWAGANDHA | HUMAN CARCINOGENESIS | MULTIDISCIPLINARY SCIENCES | TUMOR | IDENTIFICATION | DERIVATIVES | LEAF EXTRACT | HNRNP-K | CONSTITUENTS | Osteosarcoma - drug therapy | Neoplasm Transplantation | Plant Extracts - chemistry | Cell Proliferation | Reactive Oxygen Species - metabolism | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Cyclin B1 - metabolism | Dose-Response Relationship, Drug | Neoplasm Metastasis | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Malvaceae - chemistry | Fibroblasts - metabolism | Signal Transduction | Tumor Suppressor Protein p53 - metabolism | Xenograft Model Antitumor Assays | Poly(ADP-ribose) Polymerases - metabolism | Animals | Cell Cycle | Mice, Nude | Plant Roots - chemistry | Cell Line, Tumor | Mice | Mice, Inbred BALB C | DNA Damage | Antineoplastic Agents, Phytogenic - pharmacology | Osteosarcoma - pathology | Apoptosis | Care and treatment | Research | Health aspects | Materia medica, Vegetable | Plant extracts | Cancer | Bax protein | Bcl-2 protein | Toxicity | Roots | p53 Protein | DNA damage | Cytotoxicity | Identification | Metastasis | Cancer therapies | Cyclin B1 | Anticancer properties | Metastases | Proteins | Biomedical materials | Cell growth | Osteosarcoma | Rodents | Xenografts | Cell cycle | Fibroblasts | Biocompatibility | Drug dosages | Deoxyribonucleic acid--DNA | Animal sciences | Poly(ADP-ribose) polymerase | Breast cancer | Signaling | Bone cancer | Environmental science | Molecular modelling | Lungs | Antitumor activity | Laboratory animals | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e55316
Neuroblastoma is an aggressive childhood disease of the sympathetic nervous system. Treatments are often ineffective and have serious side effects.... 
CANCER-CELLS | MATRIX METALLOPROTEINASES | NERVOUS-SYSTEM | CELL-ADHESION MOLECULE | RETINOIC ACID | NEURITE OUTGROWTH | CYCLIN D1 | MULTIDISCIPLINARY SCIENCES | HEAT-SHOCK RESPONSE | TUMOR-CELLS | POLYSIALIC ACID | Water | Plant Extracts - pharmacology | Humans | Cell Cycle Checkpoints - physiology | DNA Primers - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | HSP70 Heat-Shock Proteins - metabolism | Fluorescein-5-isothiocyanate | Cell Differentiation - drug effects | Neuroblastoma - drug therapy | Neural Cell Adhesion Molecules - metabolism | Annexin A5 | Cell Line, Tumor | Cell Proliferation - drug effects | Phytotherapy - methods | Withania - chemistry | Heat shock proteins | Chemotherapy | Children | Cell differentiation | Cancer | Diseases | Cell proliferation | Toxicity | Differentiation (biology) | AKT protein | Metastasis | Neuroblastoma | Cyclin D1 | Kinases | Cancer therapies | Ashes | Phase transitions | Neuroblastoma cells | Cell adhesion molecules | Cell adhesion & migration | Proteins | Cell growth | Bcl-x protein | Cell cycle | Cell adhesion | Polysialylation | G1 phase | Translocation | Neural cell adhesion molecule | Medical treatment | Hsp70 protein | Radiation therapy | Sympathetic nervous system | Signaling | Side effects | Phytochemicals | Acids | Morphology | Apoptosis
Journal Article