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1. Full Text Humans detect snakes more accurately and quickly than other animals under natural visual scenes: a flicker paradigm study
by Kawai, Nobuyuki and Qiu, Huachen
Cognition & emotion, ISSN 0269-9931, 08/2019, pp. 1 - 7
Threat detection is crucial to survival. Studies using unnatural visual scene settings (i.e. visual search tasks) have shown that humans and primates are able... 
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2. Full Text The “social” facilitation of eating without the presence of others: Self-reflection on eating makes food taste better and people eat more
by Nakata, Ryuzaburo and Kawai, Nobuyuki
Physiology & Behavior, ISSN 0031-9384, 2017, Volume 179, pp. 23 - 29
Abstract Food tastes better and people eat more of it when eaten with company than alone. Although several explanations have been proposed for this social... 
Psychiatry | Eating with others | Eating alone | Mirror | Elderly adults | Social facilitation
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3. Full Text Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
by Nishimoto, Norihiro and Miyasaka, Nobuyuki and Yamamoto, Kazuhiko and Kawai, Shinichi and Takeuchi, Tsutomu and Azuma, Junichi and Kishimoto, Tadamitsu
Modern Rheumatology, ISSN 1439-7595, 2/2009, Volume 19, Issue 1, pp. 12 - 19
We investigated the clinical efficacy and safety of tocilizumab (a humanized anti-IL-6 receptor antibody) monotherapy in active rheumatoid arthritis (RA)... 
Immunology | Medicine & Public Health | Tocilizumab | Orthopedics | Rheumatoid arthritis | Rheumatology | Internal Medicine | Clinical trial | Vascular endothelial growth factor | Interleukin-6 | CONTROLLED-TRIAL | PERMEABILITY FACTOR | ANGIOGENESIS | SYNOVIAL-FLUID | VEGF | ANTIBODY | RHEUMATOLOGY | CELL GROWTH | RA | BENEFIT | DOUBLE-BLIND | Double-Blind Method | Antirheumatic Agents - administration & dosage | Arthritis, Rheumatoid - blood | Humans | Middle Aged | Vascular Endothelial Growth Factor A - blood | Antibodies, Monoclonal - therapeutic use | Male | Treatment Outcome | Receptors, Interleukin-6 - antagonists & inhibitors | Methotrexate - therapeutic use | Dose-Response Relationship, Drug | Young Adult | Antibodies, Monoclonal, Humanized | Antibodies, Monoclonal - administration & dosage | Arthritis, Rheumatoid - drug therapy | Adult | Female | Methotrexate - administration & dosage | Aged | Drug Therapy, Combination | Receptors, Interleukin-6 - blood | Arthritis, Rheumatoid - diagnosis | Antirheumatic Agents - therapeutic use | Patient safety | Clinical trials | Pharmacology | Effectiveness | Original
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4. Full Text Focal neuronal damage in patients with neuropsychological impairment after diffuse traumatic brain injury: Evaluation using 11C-flumazenil positron emission tomography with statistical image analysis
by Kawai, Nobuyuki and Maeda, Yukito and Kudomi, Nobuyuki and Yamamoto, Yuka and Nishiyama, Yoshihiro and Tamiya, Takashi
Journal of Neurotrauma, ISSN 0897-7151, 12/2010, Volume 27, Issue 12, pp. 2131 - 2138
This study was conducted to identify the regional neuronal damage occurring in patients with neuropsychological impairment following diffuse traumatic brain... 
cognitive function | traumatic brain injury | flumazenil | positron emission tomography | neuronal loss | Brain - diagnostic imaging | Cognition Disorders - physiopathology | Cognition Disorders - diagnostic imaging | Brain - physiopathology | Humans | Middle Aged | Carbon Isotopes | Male | Cognition | Brain Injuries - physiopathology | Neuropsychological Tests | Brain Injuries - diagnostic imaging | Flumazenil | Neurons - diagnostic imaging | Image Processing, Computer-Assisted | Radionuclide Imaging | Brain Mapping | Adult | Female | Brain Injuries - psychology | Cognition Disorders - psychology | Statistical analysis | Neurons | Tomography | Brain damage | Neuropsychology | Drug therapy | Patients
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5. Full Text Breaking snake camouflage: Humans detect snakes more accurately than other animals under less discernible visual conditions
by Kawai, Nobuyuki and He, Hongshen
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164342
Humans and non-human primates are extremely sensitive to snakes as exemplified by their ability to detect pictures of snakes more quickly than those of other... 
FEAR | ATTENTION | EVOLUTION | RECOGNITION | MULTIDISCIPLINARY SCIENCES | STIMULI | GRASS | EMOTION | PREPAREDNESS | PULVINAR | YOUNG-CHILDREN | Cats | Visual Perception - physiology | Humans | Birds | Male | Reaction Time | Snakes | Young Adult | Animals | Fishes | Adolescent | Adult | Female | Photic Stimulation | Attentional bias | Wildlife conservation | Endangered species | Primates | Change blindness | Pictures | Random noise | Bias | Images | Prey | Visual system | Information science | Predators | Spiders | Camouflage | Evolution | Animal cognition
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6. Topics Arising from the WRC-15 with Respect to Satellite-Related Agenda Items
by Kawai, Nobuyuki and Imata, Satoshi
IEICE - Transactions on Communications, ISSN 0916-8516, 10/2016, Volume E99.B, Issue 10, pp. 2113 - 2120
Along with remarkable advancement of radiocommunication services including satellite services, the radio-frequency spectrum and geostationary-satellite orbit... 
Natural resources | Satellites | Allocations | Government regulations | Communication satellites | Satellite communications
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7. Full Text Japanese monkeys (Macaca fuscata) quickly detect snakes but not spiders: Evolutionary origins of fear-relevant animals
by Kawai, Nobuyuki and Koda, Hiroki
Journal of Comparative Psychology, ISSN 0735-7036, 08/2016, Volume 130, Issue 3, pp. 299 - 303
Humans quickly detect the presence of evolutionary threats through visual perception. Many theorists have considered humans to be predisposed to respond to... 
Snake detection theory | Macaque monkeys | Spiders | Snakes | Evolutionarily fear-relevant animals | ATTENTION | macaque monkeys | RHESUS-MONKEYS | evolutionarily fear-relevant animals | STIMULI | ADULTS | snakes | spiders | THREAT | PSYCHOLOGY | PSYCHOLOGY, MULTIDISCIPLINARY | EVOLVED MODULE | ZOOLOGY | PICTURES | GRASS | BEHAVIORAL SCIENCES | MULATTA | YOUNG-CHILDREN | snake detection theory | Monkeys | Threat (Psychology) | Behavior | Animal behavior | Analysis | Visual perception | Wolves | Comparative analysis | Dogs | Animal cognition
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8. Deciphering the ancient universe with gamma-ray bursts
: Terrsa, Kyoto, Japan, 19-23 April 2010
by Kawai, Nagataki and Nagataki, Shigehiro
2010, Volume 1279.
Origin | Gamma ray bursts
Conference Proceeding
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9. Full Text Evaluation of 3′-deoxy-3′-[18F]-fluorothymidine (18F-FLT) kinetics correlated with thymidine kinase-1 expression and cell proliferation in newly diagnosed gliomas
by Shinomiya, Aya and Kawai, Nobuyuki and Okada, Masaki and Miyake, Keisuke and Nakamura, Takehiro and Kushida, Yoshio and Haba, Reiji and Kudomi, Nobuyuki and Yamamoto, Yuka and Tokuda, Masaaki and Tamiya, Takashi
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 1/2013, Volume 40, Issue 2, pp. 175 - 185
The thymidine analog 3′-deoxy-3′-[18F]fluorothymidine (18F-FLT) has been developed as a positron emission tomography (PET) tracer to assess the proliferation... 
18 F-Fluorothymidine | Thymidine kinase-1 | Medicine & Public Health | Glioma | Orthopedics | Oncology | Nuclear Medicine | Proliferation | Imaging / Radiology | Cardiology | Positron emission tomography | F-Fluorothymidine | FDG | BRAIN-TUMORS | POSITRON-EMISSION-TOMOGRAPHY | IN-VIVO | FLT-PET | F-18-Fluorothymidine | IMAGING PROLIFERATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HIGH-GRADE GLIOMA | Dideoxynucleosides - pharmacology | Phosphorylation | Cell Proliferation | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Magnetic Resonance Imaging - methods | Male | Brain Neoplasms - metabolism | Glioma - metabolism | Polymerase Chain Reaction - methods | Gene Expression Regulation, Enzymologic | Immunohistochemistry - methods | Thymidine Kinase - biosynthesis | Adult | Female | Aged | Kinetics | Blood-Brain Barrier | Tomography | Nuclear medicine | Metastasis | Kinases | Tumors
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10. Full Text Correlation of 4′-[methyl-11C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with 11C-methionine uptake
by Tanaka, Kenichi and Yamamoto, Yuka and Maeda, Yukito and Yamamoto, Hiroyuki and Kudomi, Nobuyuki and Kawai, Nobuyuki and Toyohara, Jun and Nishiyama, Yoshihiro
Annals of Nuclear Medicine, ISSN 0914-7187, 2/2016, Volume 30, Issue 2, pp. 89 - 96
A novel radiopharmaceutical, 4′-[methyl-11C]thiothymidine (11C-4DST), has been developed as an in vivo cell proliferation marker based on the DNA incorporation... 
Medicine & Public Health | Glioma | 11 C-MET | 11 C-4DST | Nuclear Medicine | Proliferation | Imaging / Radiology | PET | C-4DST | C-MET
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11. Full Text Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
by Nishimoto, Norihiro and Hashimoto, Jun and Miyasaka, Nobuyuki and Yamamoto, Kazuhiko and Kawai, Shinichi and Takeuchi, Tsutomu and Murata, Norikazu and van der Heijde, Désirée and Kishimoto, Tadamitsu
Annals of the Rheumatic Diseases, ISSN 0003-4967, 09/2007, Volume 66, Issue 9, pp. 1162 - 1167
Objective: To evaluate the ability of tocilizumab (a humanised anti-IL-6 receptor antibody) monotherapy to inhibit progression of structural joint damage in... 
CRITERIA | THERAPY | PROTEIN | SYNOVIAL-FLUID | SOLUBLE INTERLEUKIN-6 | GROWTH | SERUM | RHEUMATOLOGY | ANTI-INTERLEUKIN-6 RECEPTOR ANTIBODY | STIMULATORY FACTOR-II | DISEASE-ACTIVITY | Interleukin-6 - antagonists & inhibitors | Foot Joints - diagnostic imaging | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Methotrexate - therapeutic use | Arthritis, Rheumatoid - diagnostic imaging | Antibodies, Monoclonal, Humanized | Bacterial Infections - complications | Arthritis, Rheumatoid - drug therapy | Hand Joints - diagnostic imaging | Antirheumatic Agents - adverse effects | Adult | Female | Antirheumatic Agents - therapeutic use | Severity of Illness Index | Double-Blind Method | Treatment Outcome | Disease Progression | Radiography | Methotrexate - adverse effects | Analysis of Variance | Aged | Arthritis, Rheumatoid - immunology | Antirheumatic agents | Rheumatoid arthritis | Patient outcomes | Physiological aspects | Development and progression | Dosage and administration | Diagnosis | Research | Drug therapy | Interleukin-6 | Studies | Surveillance | Disease | Rheumatism | Nonsteroidal anti-inflammatory drugs | Family medical history | Drug dosages | Epidemiology | Extended Report
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12. Full Text Efficacy and safety of tacrolimus for lupus nephritis: a placebo-controlled double-blind multicenter study
by Miyasaka, Nobuyuki and Kawai, Shinichi and Hashimoto, Hiroshi
Modern Rheumatology, ISSN 1439-7595, 12/2009, Volume 19, Issue 6, pp. 606 - 615
We evaluated the efficacy and safety of tacrolimus in patients receiving glucocorticoid therapy for lupus nephritis. Patients with persistent nephritis were... 
Immunology | Systemic lupus erythematosus | Medicine & Public Health | Tacrolimus | Orthopedics | Rheumatology | Internal Medicine | Immunosuppressive drugs | Lupus nephritis | Randomized controlled trial | COMPLEMENT | RHEUMATOLOGY | ERYTHEMATOSUS | DISEASE-ACTIVITY | CYCLOSPORINE-A | THERAPY | INTRAVENOUS CYCLOPHOSPHAMIDE | MYASTHENIA-GRAVIS | LONG-TERM TREATMENT | MYCOPHENOLATE-MOFETIL | RENAL BIOPSY | Severity of Illness Index | Double-Blind Method | Drug Administration Schedule | Tacrolimus - blood | Urinalysis | Complement C3 - metabolism | Humans | Middle Aged | Lupus Nephritis - drug therapy | Male | Treatment Outcome | Tacrolimus - adverse effects | Patient Selection | Analysis of Variance | Adolescent | Statistics, Nonparametric | Creatinine - blood | Adult | Female | Immunosuppressive Agents - adverse effects | Lupus Nephritis - metabolism | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Lupus | Clinical trials | Drug therapy
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13. Full Text Correlation of biological aggressiveness assessed by 11C-methionine PET and hypoxic burden assessed by 18F-fluoromisonidazole PET in newly diagnosed glioblastoma
by Kawai, Nobuyuki and Maeda, Yukito and Kudomi, Nobuyuki and Miyake, Keisuke and Okada, Masaki and Yamamoto, Yuka and Nishiyama, Yoshihiro and Tamiya, Takashi
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 3/2011, Volume 38, Issue 3, pp. 441 - 450
Glioblastoma multiforme (GBM) is characterized by tissue hypoxia associated with resistance to radiotherapy and chemotherapy. To clarify the biological link... 
Gd-enhanced MRI | Medicine & Public Health | Orthopedics | MET PET | Glioblastoma | Oncology | Hypoxia | Nuclear Medicine | Cardiology | Imaging / Radiology | FMISO PET | Brain Neoplasms - diagnostic imaging | Humans | Middle Aged | Brain Neoplasms - pathology | Methionine | Male | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Tumor Burden | Brain Neoplasms - metabolism | Cell Hypoxia | Glioblastoma - diagnostic imaging | Glioblastoma - pathology | Adult | Female | Glioblastoma - metabolism | Aged
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14. Full Text Rapid Detection of Snakes by Japanese Monkeys (Macaca fuscata)
: An Evolutionarily Predisposed Visual System
by Shibasaki, Masahiro and Kawai, Nobuyuki
Journal of Comparative Psychology, ISSN 0735-7036, 5/2009, Volume 123, Issue 2, pp. 131 - 135
Humans appear extremely sensitive to biologically threatening stimuli, such as snakes. In visual search tasks, humans respond to pictures of snakes faster than... 
macaque monkeys | visual search | attentional bias | detection of snakes | fear | SEMANTIC COMMUNICATION | ATTENTION | SEARCH | FEAR-RELEVANT STIMULI | PREPAREDNESS | PSYCHOLOGY | ALARM CALLS | RESPONSES | PSYCHOLOGY, MULTIDISCIPLINARY | REARED RHESUS-MONKEYS | EVOLVED MODULE | ZOOLOGY | BEHAVIORAL SCIENCES | AMYGDALA | Visual Perception - physiology | Macaca - physiology | Sensory Thresholds | Humans | Behavior, Animal - physiology | Flowers | Reaction Time - physiology | Conditioning, Classical - physiology | Escape Reaction - physiology | Snakes | Recognition (Psychology) - physiology | Biological Evolution | Fear | Visual Pathways - physiology | Animals | Form Perception - physiology | Psychology, Comparative | Psychological aspects | Predation (Biology) | Alarm reaction | Visual search behavior | Attention | Influence | Behavior | Research | Japanese macaque | Food and nutrition | Animal behavior | Monkeys & apes
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15. Full Text 11C-methionine (MET) and 18F-fluorothymidine (FLT) PET in patients with newly diagnosed glioma
by Hatakeyama, Tetsuhiro and Kawai, Nobuyuki and Nishiyama, Yoshihiro and Yamamoto, Yuka and Sasakawa, Yasuhiro and Ichikawa, Tomotsugu and Tamiya, Takashi
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 11/2008, Volume 35, Issue 11, pp. 2009 - 2017
The purpose of this prospective study was to clarify the individual and combined role of l-methyl-11C-methionine-positron emission tomography (MET-PET) and... 
Medicine & Public Health | Cellular proliferation | Glioma | Orthopedics | Oncology | 11 C-methionine | Nuclear Medicine | Cardiology | Imaging / Radiology | Positron emission tomography | 18 F-fluorothymidine | F-fluorothymidine | C- methionine | Immunohistochemistry | Cell Proliferation | Glioma - diagnosis | Humans | Middle Aged | Child, Preschool | Male | Positron-Emission Tomography | Dideoxynucleosides | Carbon Radioisotopes - chemistry | Glioma - diagnostic imaging | Methionine - chemistry | Glioma - pathology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Tomography | Nuclear medicine | Medical diagnosis | Brain cancer
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16. Full Text Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features
by Kawai-Kitahata, Fukiko and Asahina, Yasuhiro and Tanaka, Shinji and Kakinuma, Sei and Murakawa, Miyako and Nitta, Sayuri and Watanabe, Takako and Otani, Satoshi and Taniguchi, Miki and Goto, Fumio and Nagata, Hiroko and Kaneko, Shun and Tasaka-Fujita, Megumi and Nishimura-Sakurai, Yuki and Azuma, Seishin and Itsui, Yasuhiro and Nakagawa, Mina and Tanabe, Minoru and Takano, Shinichi and Fukasawa, Mitsuharu and Sakamoto, Minoru and Maekawa, Shinya and Enomoto, Nobuyuki and Watanabe, Mamoru
Journal of Gastroenterology, ISSN 0944-1174, 5/2016, Volume 51, Issue 5, pp. 473 - 486
Genetic alterations in specific genes are critical events in carcinogenesis and hepatocellular carcinoma (HCC) progression. However, the genetic alterations... 
Medicine & Public Health | TERT | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | CTNNB1 | Surgical Oncology | TP53 | Follow-Up Studies | Humans | Middle Aged | Male | Tumor Suppressor Protein p53 - genetics | Hepatitis B Surface Antigens - blood | Hepatitis B - complications | Telomerase - genetics | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Adult | Female | Hepatitis C - complications | Liver Neoplasms - pathology | Liver Neoplasms - virology | Promoter Regions, Genetic | Liver Neoplasms - genetics | Survival Rate | Carcinoma, Hepatocellular - virology | Virus Integration | beta Catenin - genetics | Disease-Free Survival | Carcinoma, Hepatocellular - pathology | Aged | High-Throughput Nucleotide Sequencing | Mutation | Analysis | Development and progression | Genetic aspects | Hepatitis B virus | Hepatoma | Hepatitis C virus | Tumor proteins | Health aspects | Telomerase | Hepatitis B | Index Medicus
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17. Full Text Human young children as well as adults demonstrate 'superior' rapid snake detection when typical striking posture is displayed by the snake
by Masataka, Nobuo and Hayakawa, Sachiko and Kawai, Nobuyuki
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e15122
Humans as well as some nonhuman primates have an evolved predisposition to associate snakes with fear by detecting their presence as fear-relevant stimuli more... 
ATTENTION | COLOR | PHOBIAS | BIOLOGY | FEAR-RELEVANT STIMULI | GRASS | PREPAREDNESS | Phobic Disorders - physiopathology | Animals | Phobic Disorders - psychology | Humans | Child, Preschool | Fear - psychology | Adult | Reaction Time - physiology | Fear - physiology | Pattern Recognition, Visual - physiology | Photic Stimulation | Snakes | Attentional bias | Strikes | Interactive computer systems | Bias | Flowers | Posture | Fear & phobias | Fear | Reaction time | Primates | Photographs | Adults | Trends | Children | Stimuli | Animal cognition
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