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1. Full Text Constitutive GDP/GTP Exchange and Secretion-dependent GTP Hydrolysis Activity for Rab27 in Platelets
by Hirokazu Kondo and Ryutaro Shirakawa and Tomohito Higashi and Mitsunori Kawato and Mitsunori Fukuda and Toru Kita and Hisanori Horiuchi
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 39, pp. 28657 - 28665
We have previously demonstrated that Rab27 regulates dense granule secretion in platelets. Here, we analyzed the activation status of Rab27 using the thin... 
MEMBRANE-FUSION | EFFECTOR | CELLS | ACTIVATION | MYOSIN-VA | BIOCHEMISTRY & MOLECULAR BIOLOGY | EPIDERMAL-GROWTH-FACTOR | CORE GRANULE SECRETION | CA2+-INDUCED ALPHA-GRANULE | PROTEINS | IDENTIFICATION | Adaptor Proteins, Signal Transducing - chemistry | Protein Structure, Tertiary | Calcium - metabolism | Humans | Rats | Nucleotides - chemistry | Hydrolysis | Animals | Time Factors | Blood Platelets - metabolism | Protein Binding | rab27 GTP-Binding Proteins | rab GTP-Binding Proteins - chemistry | Guanosine Triphosphate - chemistry | Guanosine Diphosphate - chemistry | Index Medicus
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2. Full Text Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan　― Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry
by Yaku, Hidenori and Ozasa, Neiko and Morimoto, Takeshi and Inuzuka, Yasutaka and Tamaki, Yodo and Yamamoto, Erika and Yoshikawa, Yusuke and Kitai, Takeshi and Taniguchi, Ryoji and Iguchi, Moritake and Kato, Masashi and Takahashi, Mamoru and Jinnai, Toshikazu and Ikeda, Tomoyuki and Nagao, Kazuya and Kawai, Takafumi and Komasa, Akihiro and Nishikawa, Ryusuke and Kawase, Yuichi and Morinaga, Takashi and Su, Kanae and Kawato, Mitsunori and Sasaki, Kenichi and Toyofuku, Mamoru and Furukawa, Yutaka and Nakagawa, Yoshihisa and Ando, Kenji and Kadota, Kazushige and Shizuta, Satoshi and Ono, Koh and Sato, Yukihito and Kuwahara, Koichiro and Kato, Takao and Kimura, Takeshi and KCHF Study Investigators and on behalf of the KCHF Study Investigators
Circulation Journal, ISSN 1346-9843, 2018, Volume 82, Issue 11, pp. 2811 - 2819
Background: There is a scarcity of reports on the clinical characteristics and management practice in contemporary all-comer patients with acute decompensated... 
Heart failure | Hospitalization | Mid-range ejection fraction | Cohort study | Mortality | UNITED-STATES | DESIGN | CARDIAC & CARDIOVASCULAR SYSTEMS | RATIONALE | INITIATION | LONG-TERM OUTCOMES | REDUCED EJECTION FRACTION | END-POINTS | BORDERLINE | EPIDEMIOLOGY | WORSENING RENAL-FUNCTION
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3. Full Text Clopidogrel Resistance in Japanese Patients Scheduled for Percutaneous Coronary Intervention(Ischemic Heart Disease)
by Hoshino Kozo and Horiuchi Hisanori and Tada Tomohisa and Tazaki Junichi and Nishi Eiichiro and Kawato Mitsunori and Ikeda Tomoyuki and Yamamoto Hiromi and Akao Masaharu and Furukawa Yutaka and Shizuta Satoshi and Toma Masanao and Tamura Toshihiro and Saito Naritatsu and Doi Takahiro and Ozasa Neiko and Jinnai Toshikazu and Takahashi Kanako and Watanabe Haruyo and Yoshikawa Yuka and Nishimoto Naoko and Ouchi Chiho and Morimoto Takeshi and Kita Toru and Kimura Takeshi
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 01/2009, Volume 73, Issue 2, pp. 336 - 342
Background Dual antiplatelet therapy with acetylsalicylic acid (ASA) and a P2Y_ ADP-receptor blocker is standard for prevention of coronary stent thrombosis.... 
Adenosine diphosphate | Clopidogrel | Coronary stent | Thienopiridine | Antiplatelet drug | RESPONSIVENESS | CARDIAC & CARDIOVASCULAR SYSTEMS | HEALTHY-SUBJECTS | GENE POLYMORPHISMS | ASPIRIN | PLATELET-FUNCTION PROFILES | ATORVASTATIN | VARIABILITY | AGGREGATION | ARTERY-DISEASE | VASP PHOSPHORYLATION | Phosphorylation | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Treatment Outcome | Phosphoproteins - metabolism | Cell Adhesion Molecules - metabolism | Ticlopidine - analogs & derivatives | Angioplasty, Balloon, Coronary | Dose-Response Relationship, Drug | Coronary Stenosis - prevention & control | Myocardial Ischemia - therapy | Aged, 80 and over | Platelet Aggregation Inhibitors - pharmacology | Coronary Stenosis - ethnology | Female | Aged | Microfilament Proteins - metabolism | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - therapeutic use | Stents | Index Medicus
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4. Full Text Anemia in Patients with Severe Aortic Stenosis
by Nagao, Kazuya and Taniguchi, Tomohiko and Morimoto, Takeshi and Shiomi, Hiroki and Ando, Kenji and Kanamori, Norio and Murata, Koichiro and Kitai, Takeshi and Kawase, Yuichi and Izumi, Chisato and Miyake, Makoto and Mitsuoka, Hirokazu and Kato, Masashi and Hirano, Yutaka and Matsuda, Shintaro and Inada, Tsukasa and Murakami, Tomoyuki and Takeuchi, Yasuyo and Yamane, Keiichiro and Toyofuku, Mamoru and Ishii, Mitsuru and Minamino-Muta, Eri and Kato, Takao and Inoko, Moriaki and Ikeda, Tomoyuki and Komasa, Akihiro and Ishii, Katsuhisa and Hotta, Kozo and Higashitani, Nobuya and Kato, Yoshihiro and Inuzuka, Yasutaka and Maeda, Chiyo and Jinnai, Toshikazu and Morikami, Yuko and Saito, Naritatsu and Minatoya, Kenji and Kimura, Takeshi and Takahashi, Naoki and Fukuchi, Kohei and Imai, Masao and Tazaki, Junichi and Toyota, Toshiaki and Higami, Hirooki and Kawaji, Tetsuma and Shirai, Shinichi and Kourai, Kengo and Arita, Takeshi and Miura, Shiro and Yamaji, Kyohei and Onodera, Tomoya and Furukawa, Yutaka and Kim, Kitae and Kadota, Kazushige and Iwasaki, Keiichiro and Miyawaki, Hiroshi and Misao, Ayumi and Kuwayama, Akimune and Ohya, Masanobu and Shimada, Takenobu and Amano, Hidewo and Nakagawa, Yoshihisa and Amano, Masashi and Takahashi, Yusuke and Yoshikawa, Yusuke and Nishimura, Shunsuke and Kuroda, Maiko and Shirotani, Manabu and Miki, Shinji and Mizoguchi, Tetsu and Yokomatsu, Takafumi and Kushiyama, Akihiro and Yaku, Hidenori and Watanabe, Toshimitsu and Miyazaki, Shunichi and Takeda, Teruki and Sakaguchi, Tomoko and Maeda, Keiko and Yamaji, Masayuki and Motoyoshi, Maenaka and Tadano, Yutaka and Sakamoto, Hiroki and Motooka, Makoto and Nishikawa, Ryusuke and Eizawa, Hiroshi and Kawato, Mitsunori and Kinoshita, Minako and Aida, Kenji and Tamura, Takashi and Takahashi, Kousuke and Ko, Euihong and Akao, Masaharu and Masunaga, Nobutoyo and Ogawa, Hisashi and Iguchi, Moritake and Unoki, Takashi and Takabayashi, Kensuke and Hamatani, Yasuhiro and Yamashita, Yugo and Himura, Yoshihiro and Sato, Yukihito and ... and CURRENT AS Registry Investigators
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1924 - 11
Prognostic impact of anemia complicating severe aortic stenosis (AS) remains unclear. We assessed the impact of anemia on cardiovascular and bleeding outcomes... 
REPLACEMENT | PROGNOSTIC IMPACT | VALVE IMPLANTATION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | HEART-FAILURE | DISEASE | FERRIC CARBOXYMALTOSE | PREVALENCE | END-POINT DEFINITIONS | CONSENSUS REPORT | Anemia | Risk assessment | Hemoglobin | Stenosis | Aorta | Management | Aortic valve | Heart diseases | Bleeding
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5. Full Text Tuberous Sclerosis Tumor Suppressor Complex-like Complexes Act as GTPase-activating Proteins for Ral GTPases
by Ryutaro Shirakawa and Shuya Fukai and Mitsunori Kawato and Tomohito Higashi and Hirokazu Kondo and Tomoyuki Ikeda and Ei Nakayama and Katsuya Okawa and Osamu Nureki and Takeshi Kimura and Toru Kita and Hisanori Horiuchi
Journal of Biological Chemistry, ISSN 0021-9258, 08/2009, Volume 284, Issue 32, pp. 21580 - 21588
The small GTPases RalA and RalB are multifunctional proteins regulating a variety of cellular processes. Like other GTPases, the activity of Ral is regulated... 
EFFECTOR | RAIA GTPASE | EXOCYST | RHEB | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEOTIDE EXCHANGE FACTOR | TSC2 GAP ACTIVITY | DEPENDENT MANNER | CANCER | CELLULAR-TRANSFORMATION | DIRECT TARGET | Molecular Sequence Data | Rats | GTPase-Activating Proteins - metabolism | PC12 Cells | Brain - metabolism | Hydrolysis | Tissue Distribution | Animals | GTP Phosphohydrolases - metabolism | Tuberous Sclerosis - metabolism | Models, Biological | Swine | ral GTP-Binding Proteins - metabolism | Cytosol - metabolism | Catalysis | Index Medicus | Mechanisms of Signal Transduction
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6. Full Text Biochemical Characterization of the Rho GTPase-regulated Actin Assembly by Diaphanous-related Formins, mDia1 and Daam1, in Platelets
by Tomohito Higashi and Tomoyuki Ikeda and Ryutaro Shirakawa and Hirokazu Kondo and Mitsunori Kawato and Masahito Horiguchi and Tomohiko Okuda and Katsuya Okawa and Shuya Fukai and Osamu Nureki and Toru Kita and Hisanori Horiuchi
Journal of Biological Chemistry, ISSN 0021-9258, 03/2008, Volume 283, Issue 13, pp. 8746 - 8755
The diaphanous-related formins are actin nucleating and elongating factors. They are kept in an inactive state by an intramolecular interaction between the... 
AUTOREGULATORY DOMAIN | FISSION YEAST | BINDING PROTEIN-RHO | SERINE-THREONINE KINASE | INTEGRIN ALPHA(IIB)BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | HOMOLOGY-2 DOMAIN | PUTATIVE TARGET | MOUSE FORMIN | CAPPING PROTEIN | VERTEBRATE GASTRULATION | Adaptor Proteins, Signal Transducing - chemistry | Amino Acid Sequence | Humans | Actins - metabolism | Molecular Sequence Data | Biochemistry | Blood Platelets - metabolism | rho GTP-Binding Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Biochemical Phenomena | Kinetics | Adaptor Proteins, Signal Transducing - metabolism | Index Medicus
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7. Full Text Effects of obstructive sleep apnea with intermittent hypoxia on platelet aggregability
by Oga, Toru and Chin, Kazuo and Tabuchi, Arata and Kawato, Mitsunori and Morimoto, Takeshi and Takahashi, Kenichi and Handa, Tomohiro and Takahashi, Kanako and Taniguchi, Ryoji and Kondo, Hirokazu and Mishima, Michiaki and Kita, Toru and Horiuchi, Hisanori
Journal of atherosclerosis and thrombosis, ISSN 1340-3478, 2009, Volume 16, Issue 6, pp. 862 - 869
Aim: Obstructive sleep apnea (OSA) is a risk factor for cardiovascular diseases. Platelets play key roles in the development of atherothrombosis. Several... 
ACTIVATION | RISK-FACTORS | ATHEROTHROMBOSIS | Nasal continuous positive airway pressure | DISORDERS | NECROSIS-FACTOR-ALPHA | MECHANISMS | Total hypoxic time | DISEASE | PERIPHERAL VASCULAR DISEASE | Oxygen desaturation index | POSITIVE AIRWAY PRESSURE | ASSOCIATION | AGGREGATION | Continuous Positive Airway Pressure | Humans | Middle Aged | Risk Factors | Sleep Apnea, Obstructive - blood | Male | Snoring | Platelet Aggregation | Hypoxia - blood | Platelet Activation | Adult | Female | Thrombosis - blood | Index Medicus
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8. Full Text Action of Aspirin on Whole Blood-Aggregation Evaluated by the Screen Filtration Pressure Method
by Tabuchi, Arata and Taniguchi, Ryoji and Takahashi, Kanako and Kondo, Hirokazu and Kawato, Mitsunori and Morimoto, Takeshi and Kimura, Takeshi and Kita, Toru and Horiuchi, Hisanori
Circulation Journal, ISSN 1346-9843, 2008, Volume 72, Issue 3, pp. 420 - 426
Background There are few monitoring systems widely used in clinical practice for evaluating the effectiveness of aspirin therapy, so in the present study... 
Aggregation | Aspirin | Screen filtration pressure method | Whole blood-aggregation | Platelet-aggregation threshold index (PATI) | CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | screen filtration pressure method | MYOCARDIAL-INFARCTION | PLATELET-AGGREGATION | AGGREGOMETER | aggregation | DEATH | platelet-aggregation threshold index (PATI) | ANTIPLATELET THERAPY | STROKE | HIGH-RISK | RESISTANCE | aspirin | whole blood-aggregation | Hematologic Tests - methods | Humans | Middle Aged | Blood Platelets | Male | Pressure | Adenosine Diphosphate - pharmacology | Dose-Response Relationship, Drug | Platelet Aggregation Inhibitors - pharmacology | Adult | Collagen - pharmacology | Platelet Aggregation - drug effects | Aspirin - pharmacology | Filtration - methods | Index Medicus
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9. Full Text Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway
by Mitsunori Kawato and Ryutaro Shirakawa and Hirokazu Kondo and Tomohito Higashi and Tomoyuki Ikeda and Katsuya Okawa and Shuya Fukai and Osamu Nureki and Toru Kita and Hisanori Horiuchi
Journal of Biological Chemistry, ISSN 0021-9258, 01/2008, Volume 283, Issue 1, pp. 166 - 174
Non-hydrolyzable GTP analogues, such as guanosine 5′-(β, γ-imido)triphosphate (GppNHp), induce granule secretion from permeabilized platelets in the... 
EFFECTOR | ACTIVATION | EPITHELIAL-CELLS | EXOCYTOSIS | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CA2+-INDUCED ALPHA-GRANULE | GROWTH-FACTOR | BINDING PROTEIN | PERMEABILIZED PLATELETS | SEC6/8 COMPLEX | Guanosine Triphosphate - pharmacology | Calcium - metabolism | Vesicular Transport Proteins - metabolism | Humans | Cytoplasmic Granules - secretion | Recombinant Fusion Proteins - metabolism | Exocytosis - drug effects | Dose-Response Relationship, Drug | Glutathione Transferase - genetics | Thrombin - pharmacology | ral GTP-Binding Proteins - metabolism | Cytoplasmic Granules - metabolism | Protein Binding - drug effects | Blood Platelets - drug effects | Calcium - pharmacology | Cytoplasmic Granules - drug effects | Vesicular Transport Proteins - genetics | Glutathione Transferase - metabolism | Guanylyl Imidodiphosphate - pharmacology | Blood Platelets - secretion | Blotting, Western | Signal Transduction - drug effects | Blood Platelets - metabolism | Recombinant Fusion Proteins - genetics | ral GTP-Binding Proteins - genetics | Index Medicus
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10. Full Text Evaluation of the Antiplatelet Effects of Cilostazol, a Phosphodiesterase 3 Inhibitor, by VASP Phosphorylation and Platelet Aggregation
by Yamamoto, Hiromi and Takahashi, Kanako and Watanabe, Haruyo and Yoshikawa, Yuka and Shirakawa, Ryutaro and Higashi, Tomohito and Kawato, Mitsunori and Ikeda, Tomoyuki and Tabuchi, Arata and Morimoto, Takeshi and Kita, Toru and Horiuchi, Hisanori
Circulation Journal, ISSN 1346-9843, 2008, Volume 72, Issue 11, pp. 1844 - 1851
Background Cilostazol, a phosphodiesterase 3 inhibitor, is an antiplatelet drug that is widely used for preventing cardiovascular events, although, to date,... 
Signal transduction | Antiplatelet | Prostaglandins | Cilostazol | Platelets | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | MECHANISM | THROMBOSIS | ASPIRIN RESISTANCE | Cilostazol Platelets | WHOLE-BLOOD | CLOPIDOGREL | TICLOPIDINE | NITRIC-OXIDE | RESTENOSIS | INTER-SOCIETY CONSENSUS | Humans | Middle Aged | Phosphodiesterase 3 Inhibitors | Alprostadil - pharmacology | Male | Phosphoproteins - metabolism | Cell Adhesion Molecules - metabolism | Blood Platelets - metabolism | Tetrazoles - administration & dosage | Platelet Aggregation Inhibitors - administration & dosage | Adult | Microfilament Proteins - metabolism | Platelet Aggregation - drug effects | Phosphorylation - drug effects | Index Medicus
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11. Full Text Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase
by Higashi, Tomohito and Ikeda, Tomoyuki and Murakami, Takaaki and Shirakawa, Ryutaro and Kawato, Mitsunori and Okawa, Katsuya and Furuse, Mikio and Kimura, Takeshi and Kita, Toru and Horiuchi, Hisanori
Journal of Biological Chemistry, ISSN 0021-9258, 05/2010, Volume 285, Issue 21, pp. 16231 - 16238
Eukaryotic cells dynamically reorganize the actin cytoskeleton to regulate various cellular activities, such as cell shape change, cell motility, cytokinesis,... 
CAENORHABDITIS-ELEGANS | EMBRYONIC-DEVELOPMENT | MECHANISM | DROSOPHILA-MELANOGASTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROFILIN | NUCLEATION | BINDING PROTEIN | SACCHAROMYCES-CEREVISIAE | DOMAINS | GELSOLIN-LIKE | Adaptor Proteins, Signal Transducing - chemistry | Microfilament Proteins - chemistry | NIH 3T3 Cells | rho GTP-Binding Proteins - genetics | Humans | Actins - metabolism | Guanosine Triphosphate - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Cell Movement - physiology | Actins - genetics | Animals | Receptors, Cytoplasmic and Nuclear - chemistry | rho GTP-Binding Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Actins - chemistry | rho GTP-Binding Proteins - chemistry | Guanosine Triphosphate - genetics | Biological Transport - physiology | Guanosine Triphosphate - chemistry | Mice | Microfilament Proteins - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Microfilament Proteins - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Signal Transduction | Actin | G Proteins | Subcellular Organelles | Cell Shape | Low Molecular Weight | Rho | Cytoskeleton | G-proteins | Formin | Cell Biology | Cytoskeletal Reorganization
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12. Full Text Impact of Platelet Reactivity on Long-term Clinical Outcomes and Bleeding Events in Japanese Patients Receiving Antiplatelet Therapy with Aspirin
by Yamane, Keiichiro and Ikeda, Tomoyuki and Taniguchi, Ryoji and Watanabe, Shin and Kawato, Mitsunori and Kondo, Hirokazu and Shirakawa, Ryutaro and Higashi, Tomohito and Toma, Masanao and Tabuchi, Arata and Tamura, Toshihiro and Takahashi, Kanako and Watanabe, Haruyo and Yoshikawa, Yuka and Kita, Toru and Kimura, Takeshi and Horiuchi, Hisanori
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2012, Volume 19, Issue 12, pp. 1142 - 1153
Aim: Aspirin is an antiplatelet drug widely used for the prevention of cardiovascular disease; however, it is known to increase bleeding events. A low response... 
Antiplatelet therapy | Clinical outcome | Aspirin | Aspirin low responder | Bleeding | ACETYLSALICYLIC-ACID | MYOCARDIAL-INFARCTION | CARDIOVASCULAR EVENTS | PERCUTANEOUS CORONARY INTERVENTION | CLOPIDOGREL | LOW-DOSE ASPIRIN | HIGH-RISK | DOUBLE-BLIND | RESISTANCE | PERIPHERAL VASCULAR DISEASE | PRIMARY PREVENTION | Body Mass Index | Cardiovascular Diseases - etiology | Prognosis | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Humans | Japan | Middle Aged | Risk Factors | Male | Treatment Outcome | Hemorrhage - prevention & control | Time Factors | Blood Platelets - metabolism | Female | Aged | Aspirin - therapeutic use | Retrospective Studies | Hemorrhage - chemically induced | Blood Platelets - drug effects | Platelet Aggregation Inhibitors - therapeutic use | Index Medicus
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13. Full Text Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Severe Aortic Stenosis
by Taniguchi, Tomohiko and Morimoto, Takeshi and Shiomi, Hiroki and Ando, Kenji and Kanamori, Norio and Murata, Koichiro and Kitai, Takeshi and Kadota, Kazushige and Izumi, Chisato and Nakatsuma, Kenji and Sasa, Tomoki and Watanabe, Hirotoshi and Watanabe, Toshimitsu and Kuwabara, Yasuhide and Makiyama, Takeru and Ono, Koh and Shizuta, Satoshi and Kato, Masashi and Kato, Takao and Kato, Yoshihiro and Saito, Naritatsu and Minatoya, Kenji and Kimura, Takeshi and Imai, Masao and Tazaki, Junichi and Toyota, Toshiaki and Higami, Hirooki and Kawaji, Tetsuma and Shirai, Shinichi and Kourai, Kengo and Arita, Takeshi and Miura, Shiro and Yamaji, Kyohei and Yamaji, Masayuki and Aoyama, Takeshi and Onodera, Tomoya and Furukawa, Yutaka and Kim, Kitae and Kawase, Yuichi and Iwasaki, Keiichiro and Miyawaki, Hiroshi and Misao, Ayumi and Kuwayama, Akimune and Ohya, Masanobu and Shimada, Takenobu and Amano, Masashi and Amano, Hidewo and Nakagawa, Yoshihisa and Miyake, Makoto and Takahashi, Yusuke and Takahashi, Naoki and Takahashi, Kousuke and Yoshikawa, Yusuke and Nishimura, Shunsuke and Kuroda, Maiko and Shirotani, Manabu and Mitsuoka, Hirokazu and Miki, Shinji and Mizoguchi, Tetsu and Yokomatsu, Takafumi and Kushiyama, Akihiro and Yaku, Hidenori and Miyazaki, Shunichi and Hirano, Yutaka and Matsuda, Mitsuo and Matsuda, Shintaro and Sugioka, Sachiko and Inada, Tsukasa and Nagao, Kazuya and Fukuchi, Kohei and Murakami, Tomoyuki and Mabuchi, Hiroshi and Takeda, Teruki and Sakaguchi, Tomoko and Sakaguchi, Genichi and Maeda, Keiko and Maeda, Chiyo and Maenaka, Motoyoshi and Tadano, Yutaka and Sakamoto, Hiroki and Takeuchi, Yasuyo and Motooka, Makoto and Nishikawa, Ryusuke and Eizawa, Hiroshi and Yamane, Keiichiro and Kawato, Mitsunori and Kinoshita, Minako and Aida, Kenji and Tamura, Takashi and Toyofuku, Mamoru and Ko, Euihong and Akao, Masaharu and Ishii, Katsuhisa and Ishii, Mitsuru and Masunaga, Nobutoyo and Ogawa, Hisashi and Iguchi, Moritake and Unoki, Takashi and Takabayashi, Kensuke and Hamatani, Yasuhiro and ... and CURRENT AS Registry Investigators
JACC: Cardiovascular Interventions, ISSN 1936-8798, 01/2018, Volume 11, Issue 2, pp. 145 - 157
The aim of this study was to evaluate the prognostic impact of left ventricular ejection fraction (LVEF) in patients with severe aortic stenosis (AS). The... 
aortic stenosis | aortic valve replacement | prognosis | left ventricular ejection fraction | LOW-GRADIENT | CARDIAC & CARDIOVASCULAR SYSTEMS | PRACTICE GUIDELINES | OF-CARDIOLOGY | AMERICAN-COLLEGE | VALVULAR HEART-DISEASE | END-POINT DEFINITIONS | TRANSCATHETER | PARADOXICAL LOW-FLOW | ASSOCIATION TASK-FORCE | VALVE-REPLACEMENT | Index Medicus
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14. Full Text PJ-577 The Antiplatelet Effect of Aspirin does not Change after 2-year Interval(PJ097,Cardiovascular Pharmacology (Clinical) (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
by Ikeda Tomoyuki and Taniguchi Ryoji and Kondo Hirokazu and Kawato Mitsunori and Kita Toru and Horiuchi Hisanori
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 03/2009, Volume 73
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15. Full Text Asymptomatic versus symptomatic patients with severe aortic stenosis
by Kanamori, Norio and Taniguchi, Tomohiko and Morimoto, Takeshi and Shiomi, Hiroki and Ando, Kenji and Murata, Koichiro and Kitai, Takeshi and Kawase, Yuichi and Izumi, Chisato and Miyake, Makoto and Mitsuoka, Hirokazu and Kato, Masashi and Hirano, Yutaka and Matsuda, Shintaro and Nagao, Kazuya and Inada, Tsukasa and Mabuchi, Hiroshi and Takeuchi, Yasuyo and Yamane, Keiichiro and Toyofuku, Mamoru and Ishii, Mitsuru and Minamino-Muta, Eri and Kato, Takao and Inoko, Moriaki and Ikeda, Tomoyuki and Komasa, Akihiro and Ishii, Katsuhisa and Hotta, Kozo and Higashitani, Nobuya and Kato, Yoshihiro and Inuzuka, Yasutaka and Maeda, Chiyo and Jinnai, Toshikazu and Morikami, Yuko and Saito, Naritatsu and Minatoya, Kenji and Aoyama, Takeshi and Kimura, Takeshi and CURRENT AS Registry Investigators and CURRENT AS registry Investigators
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 10080 - 10
It is unknown how much different are the clinical outcomes between asymptomatic and symptomatic patients with severe aortic stenosis (AS). In the CURRENT AS... 
SURGERY | REPLACEMENT | DECISION | VALVE IMPLANTATION | HEART-ASSOCIATION | MULTIDISCIPLINARY SCIENCES | DISEASE | RISK | OUTCOMES | ELDERLY-PATIENTS | END-POINT DEFINITIONS | Dyspnea | Syncope | Electrocardiography | Stenosis | Aorta | Angina | Ventricle | Respiration | Aortic valve | Heart diseases
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