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science & technology (27) 27
life sciences & biomedicine (24) 24
humans (19) 19
cardiovascular system & cardiology (15) 15
male (15) 15
cardiac & cardiovascular systems (13) 13
female (13) 13
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aged, 80 and over (10) 10
artificial stone (10) 10
casings or constructional details of electric apparatus (10) 10
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compositions thereof, e.g. mortars, concrete or like buildingmaterials (10) 10
concrete (10) 10
electric techniques not otherwise provided for (10) 10
electricity (10) 10
lime, magnesia (10) 10
manufacture of assemblages of electrical components (10) 10
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refractories (10) 10
slag (10) 10
treatment of natural stone (10) 10
treatment outcome (9) 9
heart failure (7) 7
hospitalization (7) 7
japan (7) 7
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prognosis (7) 7
retrospective studies (7) 7
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aortic valve stenosis - mortality (6) 6
mortality (6) 6
severity of illness index (6) 6
aortic valve stenosis - therapy (5) 5
biochemistry & molecular biology (5) 5
blood platelets - metabolism (5) 5
patients (5) 5
registries (5) 5
aortic stenosis (4) 4
body mass index (4) 4
clinical outcomes (4) 4
follow-up studies (4) 4
hospitals (4) 4
original research (4) 4
valvular heart disease (4) 4
adaptor proteins, signal transducing - chemistry (3) 3
adult (3) 3
animals (3) 3
aortic valve replacement (3) 3
aortic valve stenosis - complications (3) 3
aortic valve stenosis - diagnostic imaging (3) 3
aortic valve stenosis - physiopathology (3) 3
aspirin (3) 3
biochemistry (3) 3
biological and medical sciences (3) 3
cardiology (3) 3
dose-response relationship, drug (3) 3
food industries (3) 3
fundamental and applied biological sciences. psychology (3) 3
japan - epidemiology (3) 3
medicine (3) 3
microfilament proteins - metabolism (3) 3
multidisciplinary sciences (3) 3
platelet aggregation - drug effects (3) 3
platelet aggregation inhibitors - pharmacology (3) 3
science & technology - other topics (3) 3
actins - metabolism (2) 2
acute disease (2) 2
adaptor proteins, signal transducing - genetics (2) 2
adaptor proteins, signal transducing - metabolism (2) 2
adenosine diphosphate (2) 2
albumin (2) 2
alcoholic beverages (2) 2
antiplatelet drug (2) 2
antiplatelet therapy (2) 2
aortic valve replacement/transcather aortic valve implantation (2) 2
aortic valve stenosis - diagnosis (2) 2
aplicaciones del ordenador (2) 2
application des ordinateurs (2) 2
aspirin - pharmacology (2) 2
asymptomatic diseases (2) 2
basic electric elements (2) 2
bebidas alcoholicas (2) 2
beer (2) 2
biotechnology & applied microbiology (2) 2
blood platelets - drug effects (2) 2
boisson alcoolisee (2) 2
brandies, spirituous liquors (2) 2
brassage (2) 2
brewing (2) 2
calcium - metabolism (2) 2
calculating (2) 2
cardiac arrhythmia (2) 2
cardiovascular disease (2) 2
cause of death (2) 2
cell adhesion molecules - metabolism (2) 2
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1. Full Text Constitutive GDP/GTP Exchange and Secretion-dependent GTP Hydrolysis Activity for Rab27 in Platelets
by Hirokazu Kondo and Ryutaro Shirakawa and Tomohito Higashi and Mitsunori Kawato and Mitsunori Fukuda and Toru Kita and Hisanori Horiuchi
The Journal of biological chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 39, pp. 28657 - 28665
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Adaptor Proteins, Signal Transducing - chemistry | Protein Structure, Tertiary | Calcium - metabolism | Humans | Rats | Nucleotides - chemistry | Hydrolysis | Animals | Time Factors | Blood Platelets - metabolism | Protein Binding | rab27 GTP-Binding Proteins | rab GTP-Binding Proteins - chemistry | Guanosine Triphosphate - chemistry | Guanosine Diphosphate - chemistry | Index Medicus
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2. Full Text Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan　― Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry
by Yaku, Hidenori and Ozasa, Neiko and Morimoto, Takeshi and Inuzuka, Yasutaka and Tamaki, Yodo and Yamamoto, Erika and Yoshikawa, Yusuke and Kitai, Takeshi and Taniguchi, Ryoji and Iguchi, Moritake and Kato, Masashi and Takahashi, Mamoru and Jinnai, Toshikazu and Ikeda, Tomoyuki and Nagao, Kazuya and Kawai, Takafumi and Komasa, Akihiro and Nishikawa, Ryusuke and Kawase, Yuichi and Morinaga, Takashi and Su, Kanae and Kawato, Mitsunori and Sasaki, Kenichi and Toyofuku, Mamoru and Furukawa, Yutaka and Nakagawa, Yoshihisa and Ando, Kenji and Kadota, Kazushige and Shizuta, Satoshi and Ono, Koh and Sato, Yukihito and Kuwahara, Koichiro and Kato, Takao and Kimura, Takeshi and KCHF Study Investigators and on behalf of the KCHF Study Investigators
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 2018, Volume 82, Issue 11, pp. 2811 - 2819
Heart failure | Hospitalization | Mid-range ejection fraction | Cohort study | Mortality | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Index Medicus
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3. Full Text Association with Controlling Nutritional Status (CONUT) Score and In-hospital Mortality and Infection in Acute Heart Failure
by Kato, Takao and Yaku, Hidenori and Morimoto, Takeshi and Inuzuka, Yasutaka and Tamaki, Yodo and Yamamoto, Erika and Yoshikawa, Yusuke and Kitai, Takeshi and Taniguchi, Ryoji and Iguchi, Moritake and Kato, Masashi and Takahashi, Mamoru and Jinnai, Toshikazu and Ikeda, Tomoyuki and Nagao, Kazuya and Kawai, Takafumi and Komasa, Akihiro and Nishikawa, Ryusuke and Kawase, Yuichi and Morinaga, Takashi and Su, Kanae and Kawato, Mitsunori and Seko, Yuta and Inoko, Moriaki and Toyofuku, Mamoru and Furukawa, Yutaka and Nakagawa, Yoshihisa and Ando, Kenji and Kadota, Kazushige and Shizuta, Satoshi and Ono, Koh and Sato, Yukihito and Kuwahara, Koichiro and Ozasa, Neiko and Kimura, Takeshi
Scientific reports, ISSN 2045-2322, 02/2020, Volume 10, Issue 1, pp. 3320 - 3320
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Heart Failure - complications | Acute Disease | Hospital Mortality | Infections - complications | Humans | Risk Factors | Male | Treatment Outcome | Hospitalization | C-Reactive Protein - metabolism | Heart Failure - microbiology | Aged, 80 and over | Female | Aged | Nutritional Status | Heart Failure - mortality | Heart failure | Body mass index | Cell number | Mortality | Infections | Heart diseases | Nutritional status | Cholesterol | Index Medicus
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4. Full Text Tuberous Sclerosis Tumor Suppressor Complex-like Complexes Act as GTPase-activating Proteins for Ral GTPases
by Ryutaro Shirakawa and Shuya Fukai and Mitsunori Kawato and Tomohito Higashi and Hirokazu Kondo and Tomoyuki Ikeda and Ei Nakayama and Katsuya Okawa and Osamu Nureki and Takeshi Kimura and Toru Kita and Hisanori Horiuchi
The Journal of biological chemistry, ISSN 0021-9258, 08/2009, Volume 284, Issue 32, pp. 21580 - 21588
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Molecular Sequence Data | Rats | GTPase-Activating Proteins - metabolism | PC12 Cells | Brain - metabolism | Hydrolysis | Tissue Distribution | Animals | GTP Phosphohydrolases - metabolism | Tuberous Sclerosis - metabolism | Models, Biological | Swine | ral GTP-Binding Proteins - metabolism | Cytosol - metabolism | Catalysis | Index Medicus | Mechanisms of Signal Transduction
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5. Full Text Clopidogrel Resistance in Japanese Patients Scheduled for Percutaneous Coronary Intervention(Ischemic Heart Disease)
by Hoshino Kozo and Horiuchi Hisanori and Tada Tomohisa and Tazaki Junichi and Nishi Eiichiro and Kawato Mitsunori and Ikeda Tomoyuki and Yamamoto Hiromi and Akao Masaharu and Furukawa Yutaka and Shizuta Satoshi and Toma Masanao and Tamura Toshihiro and Saito Naritatsu and Doi Takahiro and Ozasa Neiko and Jinnai Toshikazu and Takahashi Kanako and Watanabe Haruyo and Yoshikawa Yuka and Nishimoto Naoko and Ouchi Chiho and Morimoto Takeshi and Kita Toru and Kimura Takeshi
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 01/2009, Volume 73, Issue 2, pp. 336 - 342
Adenosine diphosphate | Clopidogrel | Coronary stent | Thienopiridine | Antiplatelet drug | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Phosphorylation | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Treatment Outcome | Phosphoproteins - metabolism | Cell Adhesion Molecules - metabolism | Ticlopidine - analogs & derivatives | Angioplasty, Balloon, Coronary | Dose-Response Relationship, Drug | Coronary Stenosis - prevention & control | Myocardial Ischemia - therapy | Aged, 80 and over | Platelet Aggregation Inhibitors - pharmacology | Coronary Stenosis - ethnology | Female | Aged | Microfilament Proteins - metabolism | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - therapeutic use | Stents | Index Medicus
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6. Full Text C-reactive protein at discharge and 1-year mortality in hospitalised patients with acute decompensated heart failure: an observational study
by Nishimoto, Yuji and Kato, Takao and Morimoto, Takeshi and Yaku, Hidenori and Inuzuka, Yasutaka and Tamaki, Yodo and Yamamoto, Erika and Yoshikawa, Yusuke and Kitai, Takeshi and Taniguchi, Ryoji and Iguchi, Moritake and Kato, Masashi and Takahashi, Mamoru and Jinnai, Toshikazu and Ikeda, Tomoyuki and Nagao, Kazuya and Kawai, Takafumi and Komasa, Akihiro and Nishikawa, Ryusuke and Kawase, Yuichi and Morinaga, Takashi and Su, Kanae and Kawato, Mitsunori and Seko, Yuta and Inoko, Moriaki and Toyofuku, Mamoru and Furukawa, Yutaka and Nakagawa, Yoshihisa and Ando, Kenji and Kadota, Kazushige and Shizuta, Satoshi and Ono, Koh and Kuwahara, Koichiro and Ozasa, Neiko and Sato, Yukihito and Kimura, Takeshi
BMJ open, ISSN 2044-6055, 12/2020, Volume 10, Issue 12, pp. e041068 - e041068
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Heart failure | Cardiac arrhythmia | Anemia | Mortality | Values | Infections | Patients | Clinical outcomes | Variables | Proteins | Hospitals | Tumor necrosis factor-TNF | Acute coronary syndromes | Viral infections | Index Medicus
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7. Full Text Biochemical Characterization of the Rho GTPase-regulated Actin Assembly by Diaphanous-related Formins, mDia1 and Daam1, in Platelets
by Tomohito Higashi and Tomoyuki Ikeda and Ryutaro Shirakawa and Hirokazu Kondo and Mitsunori Kawato and Masahito Horiguchi and Tomohiko Okuda and Katsuya Okawa and Shuya Fukai and Osamu Nureki and Toru Kita and Hisanori Horiuchi
The Journal of biological chemistry, ISSN 0021-9258, 03/2008, Volume 283, Issue 13, pp. 8746 - 8755
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Adaptor Proteins, Signal Transducing - chemistry | Amino Acid Sequence | Humans | Actins - metabolism | Molecular Sequence Data | Biochemistry | Blood Platelets - metabolism | Microfilament Proteins | rho GTP-Binding Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Biochemical Phenomena | Kinetics | Adaptor Proteins, Signal Transducing - metabolism | Formins | Index Medicus
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8. Full Text Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway
by Mitsunori Kawato and Ryutaro Shirakawa and Hirokazu Kondo and Tomohito Higashi and Tomoyuki Ikeda and Katsuya Okawa and Shuya Fukai and Osamu Nureki and Toru Kita and Hisanori Horiuchi
The Journal of biological chemistry, ISSN 0021-9258, 01/2008, Volume 283, Issue 1, pp. 166 - 174
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Calcium - pharmacology | Guanosine Triphosphate - pharmacology | Calcium - metabolism | Vesicular Transport Proteins - metabolism | Cytoplasmic Granules - drug effects | Humans | Vesicular Transport Proteins - genetics | Glutathione Transferase - metabolism | Guanylyl Imidodiphosphate - pharmacology | Recombinant Fusion Proteins - metabolism | Blotting, Western | Exocytosis - drug effects | Dose-Response Relationship, Drug | Glutathione Transferase - genetics | Thrombin - pharmacology | Signal Transduction - drug effects | Blood Platelets - metabolism | ral GTP-Binding Proteins - metabolism | Cytoplasmic Granules - metabolism | Protein Binding - drug effects | Recombinant Fusion Proteins - genetics | ral GTP-Binding Proteins - genetics | Blood Platelets - drug effects | Index Medicus
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9. Full Text Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase
by Higashi, Tomohito and Ikeda, Tomoyuki and Murakami, Takaaki and Shirakawa, Ryutaro and Kawato, Mitsunori and Okawa, Katsuya and Furuse, Mikio and Kimura, Takeshi and Kita, Toru and Horiuchi, Hisanori
The Journal of biological chemistry, ISSN 0021-9258, 05/2010, Volume 285, Issue 21, pp. 16231 - 16238
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Adaptor Proteins, Signal Transducing - chemistry | NIH 3T3 Cells | Humans | Actins - metabolism | Guanosine Triphosphate - metabolism | Cell Movement - physiology | Actins - genetics | Receptors, Cytoplasmic and Nuclear - chemistry | Actins - chemistry | rho GTP-Binding Proteins - chemistry | Guanosine Triphosphate - chemistry | Microfilament Proteins - metabolism | Formins | Microfilament Proteins - genetics | Microfilament Proteins - chemistry | rho GTP-Binding Proteins - genetics | Trans-Activators | Receptors, Cytoplasmic and Nuclear - genetics | Animals | rho GTP-Binding Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Guanosine Triphosphate - genetics | Biological Transport - physiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Signal Transduction | Actin | G Proteins | Subcellular Organelles | Cell Shape | Low Molecular Weight | Rho | Cytoskeleton | G-proteins | Formin | Cell Biology | Cytoskeletal Reorganization
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10. Full Text Sex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry
by Yamamoto, Erika and Kato, Takao and Yaku, Hidenori and Morimoto, Takeshi and Inuzuka, Yasutaka and Tamaki, Yodo and Ozasa, Neiko and Kitai, Takeshi and Taniguchi, Ryoji and Iguchi, Moritake and Kato, Masashi and Takahashi, Mamoru and Jinnai, Toshikazu and Ikeda, Tomoyuki and Himura, Yoshihiro and Nagao, Kazuya and Kawai, Takafumi and Komasa, Akihiro and Nishikawa, Ryusuke and Kawase, Yuichi and Morinaga, Takashi and Kawato, Mitsunori and Seko, Yuta and Toyofuku, Mamoru and Furukawa, Yutaka and Nakagawa, Yoshihisa and Ando, Kenji and Kadota, Kazushige and Shizuta, Satoshi and Ono, Koh and Sato, Yukihito and Kuwahara, Koichiro and Kimura, Takeshi and KCHF Study Investigators
ESC Heart Failure, ISSN 2055-5822, 10/2020, Volume 7, Issue 5, pp. 2485 - 2493
Heart failure | Sex difference | Prognosis | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Women | Cardiac arrhythmia | Edema | Cardiovascular disease | Gender differences | Hospitalization | Waivers | Patients | Clinical outcomes | Body mass index | Etiology | Consent | Pacemakers | Intubation | Diabetes | Kidney diseases | Age | Ejection fraction | Index Medicus
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11. Full Text Prognostic Impact of Left Ventricular Ejection Fraction in Patients With Severe Aortic Stenosis
by Taniguchi, Tomohiko and Ando, Kenji and Kanamori, Norio and Murata, Koichiro and Kadota, Kazushige and Sasa, Tomoki and Ono, Koh and Shizuta, Satoshi and Kato, Takao and Saito, Naritatsu and Minatoya, Kenji and Kimura, Takeshi and Kimura, Takeshi and Tazaki, Junichi and Higami, Hirooki and Kawaji, Tetsuma and Arita, Takeshi and Miura, Shiro and Yamaji, Kyohei and Kanamori, Norio and Onodera, Tomoya and Murata, Koichiro and Furukawa, Yutaka and Kim, Kitae and Kadota, Kazushige and Kuwayama, Akimune and Ohya, Masanobu and Shimada, Takenobu and Amano, Hidewo and Izumi, Chisato and Takahashi, Yusuke and Nishimura, Shunsuke and Miki, Shinji and Mizoguchi, Tetsu and Kushiyama, Akihiro and Yaku, Hidenori and Watanabe, Toshimitsu and Miyazaki, Shunichi and Hirano, Yutaka and Matsuda, Mitsuo and Sugioka, Sachiko and Inada, Tsukasa and Nagao, Kazuya and Takahashi, Naoki and Murakami, Tomoyuki and Mabuchi, Hiroshi and Takeda, Teruki and Sakaguchi, Tomoko and Maenaka, Motoyoshi and Sakamoto, Hiroki and Eizawa, Hiroshi and Kawato, Mitsunori and Kinoshita, Minako and Aida, Kenji and Tamura, Takashi and Toyofuku, Mamoru and Takahashi, Kousuke and Ko, Euihong and Akao, Masaharu and Ishii, Mitsuru and Masunaga, Nobutoyo and Iguchi, Moritake and Unoki, Takashi and Takabayashi, Kensuke and Yamashita, Yugo and Minamino-Muta, Eri and Kato, Takao and Ikeda, Tomoyuki and Komasa, Akihiro and Sato, Yukihito and Tsuji, Shuhei and Higashitani, Nobuya and Kouchi, Ichiro and Ikeguchi, Shigeru and Inuzuka, Yasutaka and Seki, Jyunya and Yamada, Miho and Konishi, Takashi and Jinnai, Toshikazu and Sogabe, Kouji and Tachiiri, Michiya and Matsumura, Yukiko and Ota, Chihiro and Morikami, Yuko and Minakata, Kenji and Minatoya, Kenji and Hanyu, Michiya and Yamazaki, Fumio and Komiya, Tatsuhiko and Yamanaka, Kazuo and Meshii, Katsuaki and Saga, Toshihiko and Onoe, Masahiko and Nakayama, Shogo and Iwakura, Atsushi and Shiraga, Kotaro and Ueyama, Koji and Fukumoto, Atsushi and Nishizawa, Junichiro and Kitano, Mitsuru and CURRENT AS Registry Investigators
JACC. Cardiovascular interventions, ISSN 1936-8798, 01/2018, Volume 11, Issue 2, pp. 145 - 157
aortic stenosis | aortic valve replacement | prognosis | left ventricular ejection fraction | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Ventricular Function, Left | Humans | Heart Failure - physiopathology | Male | Aortic Valve Stenosis - diagnostic imaging | Aortic Valve Stenosis - mortality | Heart Failure - therapy | Time Factors | Conservative Treatment - mortality | Echocardiography, Doppler | Aged, 80 and over | Female | Registries | Aortic Valve Stenosis - surgery | Retrospective Studies | Conservative Treatment - adverse effects | Severity of Illness Index | Risk Assessment | Japan | Risk Factors | Aortic Valve Stenosis - physiopathology | Heart Valve Prosthesis Implantation - mortality | Treatment Outcome | Hospitalization | Disease Progression | Stroke Volume | Heart Valve Prosthesis Implantation - adverse effects | Aged | Index Medicus
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