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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 37, pp. E5399 - E5407
Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5⁺) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Intestinal stem cell | Niche | Lgr5 | Deep crypt secretory cells | Reg4 | niche | intestinal stem cell | deep crypt secretory cells | HOMEOSTASIS | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | GOBLET CELLS | INTESTINAL CRYPTS | PANETH CELLS | DIFFERENTIATION | REG-IV | EXPRESSION | ADENOMAS | Biological Sciences | PNAS Plus
Journal Article
Cell Stem Cell, ISSN 1934-5909, 11/2016
Lgr5+ adult intestinal stem cells are highly proliferative throughout life. Single Lgr5+ stem cells can be cultured into three-dimensional organoids containing... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 4, pp. E610 - E619
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 4, p. E610
The adult mouse subependymal zone provides a niche for mammalian neural stem cells (NSCs). However, the molecular signature, self-renewal potential, and fate... 
Target recognition | Wnt protein | Brain stem | Homeostasis | Stem cell transplantation | Subependymal zone | Ribonucleic acid--RNA | Gene sequencing | Cell fate | Cell number | Rodents | Stem cells | Genetic analysis | Alleles | Neural stem cells | Stochastic models | Stochasticity | Gene mapping | Quantitative analysis
Journal Article
ISSN 0027-8424, 2018
The adult mouse subependymal zone provides a niche for mammalian neural stem cells (NSCs). However, the molecular signature, self-renewal potential, and fate... 
single-cell sequencing | modeling | neural stem cells | cellular dynamics | ki67
Journal Article
Nature methods, ISSN 1548-7091, 5/2014, Volume 11, Issue 5, pp. 549 - 551
We have developed a quantitative technique for sorting cells based on endogenous RNA abundance with a molecular resolution of 10-20 transcripts. We demonstrate... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2016, Volume 113, Issue 37, p. E5399
  Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5+) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Proteins | Digestive system | Stem cells | Homeostasis | Amino acids
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 09/2016, Volume 113, Issue 37, p. E5399
Leucine-rich repeat-containing G-protein coupled receptor 5-positive ([Lgr5.sup.+]) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Cell interaction | Colon (Anatomy) | Epithelial cells | Health aspects | Stem cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2016, Volume 113, Issue 37, pp. E5399 - E5407
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 09/2016, Volume 113, Issue 37, pp. E5399 - E5399
Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5+) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Journal Article
Cell Stem Cell, ISSN 1934-5909, 08/2016, Volume 19, Issue 2, p. 266
Adult mitotic tissues like the intestine, skin, and blood undergo constant turnover throughout the life of an organism. Knowing the identity of the stem cell... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2016, Volume 113, Issue 37, p. E5399
Leucine-rich repeat-containing G-protein coupled receptor 5-positive (Lgr5+ ) stem cells reside at crypt bottoms of the small and large intestine. Small... 
Journal Article
Cell Stem Cell, ISSN 1934-5909, 02/2016, Volume 18, Issue 2, p. 203
Intestinal crypts display robust regeneration upon injury. The relatively rare secretory precursors can replace lost stem cells, but it is unknown if the... 
Journal Article
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