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1. Full Text Whole-genome characterization of chemoresistant ovarian cancer
by Patch, Ann-Marie and Christie, Elizabeth L and Etemadmoghadam, Dariush and Garsed, Dale W and George, Joshy and Fereday, Sian and Nones, Katia and Cowin, Prue and Alsop, Kathryn and Bailey, Peter J and Kassahn, Karin S and Newell, Felicity and Quinn, Michael C.J and Kazakoff, Stephen and Quek, Kelly and Wilhelm-Benartzi, Charlotte and Curry, Ed and Leong, Huei San and Hamilton, Anne and Mileshkin, Linda and Au-Yeung, George and Kennedy, Catherine and Hung, Jillian and Chiew, Yoke-Eng and Harnett, Paul and Friedlander, Michael and Quinn, Michael and Pyman, Jan and Cordner, Stephen and O'Brien, Patricia and Leditschke, Jodie and Young, Greg and Strachan, Kate and Waring, Paul and Azar, Walid and Mitchell, Chris and Traficante, Nadia and Hendley, Joy and Thorne, Heather and Shackleton, Mark and Miller, David K and Arnau, Gisela Mir and Tothill, Richard W and Holloway, Timothy P and Semple, Timothy and Harliwong, Ivon and Nourse, Craig and Nourbakhsh, Ehsan and Manning, Suzanne and Idrisoglu, Senel and Bruxner, Timothy J. C and Christ, Angelika N and Poudel, Barsha and Holmes, Oliver and Anderson, Matthew and Leonard, Conrad and Lonie, Andrew and Hall, Nathan and Wood, Scott and Taylor, Darrin F and Xu, Qinying and Lynn Fink, J and Waddell, Nick and Drapkin, Ronny and Stronach, Euan and Gabra, Hani and Brown, Robert and Jewell, Andrea and Nagaraj, Shivashankar H and Markham, Emma and Wilson, Peter J and Ellul, Jason and McNally, Orla and Doyle, Maria A and Vedururu, Ravikiran and Stewart, Collin and Lengyel, Ernst and Pearson, John V and Waddell, Nicola and Defazio, Anna and Grimmond, Sean M and Bowtell, David D. L and Australian Ovarian Canc Study Grp and Australian Ovarian Cancer Study Group and The Australian Ovarian Cancer Study Group
Nature (London), ISSN 0028-0836, 05/2015, Volume 521, Issue 7553, pp. 489 - 494
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oncogene Proteins - genetics | PTEN Phosphohydrolase - genetics | Humans | Mutagenesis - genetics | Cystadenocarcinoma, Serous - genetics | DNA-Binding Proteins - genetics | Genes, Neurofibromatosis 1 | Germ-Line Mutation - genetics | Cyclin E - genetics | Cystadenocarcinoma, Serous - drug therapy | Promoter Regions, Genetic - genetics | Genome, Human - genetics | Ovarian Neoplasms - genetics | DNA Methylation | Drug Resistance, Neoplasm - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | DNA Mutational Analysis | Retinoblastoma Protein - genetics | Genes, BRCA2 | Female | Genes, BRCA1 | Ovarian Neoplasms - drug therapy | Cohort Studies | Drug Resistance, Neoplasm - drug effects | Care and treatment | Analysis | Genetic aspects | Nucleotide sequencing | Methylation | Ovarian cancer | DNA sequencing | Gene amplification | Genomes | Mutation | Metastasis | Gene expression | Chromosomes | Patients | Tumors | Index Medicus
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2. Full Text Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications
by McCart Reed, Amy Ellen and Kalaw, Emarene and Nones, Katia and Bettington, Mark and Lim, Malcolm and Bennett, James and Johnstone, Kate and Kutasovic, Jamie Rose and Saunus, Jodi Marie and Kazakoff, Stephen and Xu, Qinying and Wood, Scott and Holmes, Oliver and Leonard, Conrad and Reid, Lynne Estelle and Black, Debra and Niland, Colleen and Ferguson, Kaltin and Gresshoff, Irma and Raghavendra, Ashwini and Harvey, Kate and Cooper, Caroline and Liu, Cheng and Kalinowski, Lauren and Reid, Andrew Scott and Davidson, Morgan and Pearson, John V and Pathmanathan, Nirmala and Tse, Gary and Papadimos, David and Pathmanathan, Rajadurai and Harris, Gavin and Yamaguchi, Rin and Tan, Puay Hoon and Fox, Stephen B and O'Toole, Sandra A and Simpson, Peter Thomas and Waddell, Nicola and Lakhani, Sunil R
The Journal of pathology, ISSN 0022-3417, 02/2019, Volume 247, Issue 2, pp. 214 - 227
squamous | breast cancer | genomics | metaplastic | epithelial‐to‐mesenchymal transition | spindle | heterogeneity | epithelial-to-mesenchymal transition | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Neoplasms, Complex and Mixed - genetics | Class I Phosphatidylinositol 3-Kinases - genetics | Humans | Middle Aged | Tumor Suppressor Protein p53 - genetics | Antigens, CD - analysis | Neoplasms, Complex and Mixed - classification | Breast Neoplasms - chemistry | Keratins - analysis | Neoplasm Grading | Epithelial-Mesenchymal Transition | Female | Breast Neoplasms - classification | PTEN Phosphohydrolase - genetics | Genetic Predisposition to Disease | Cross-Sectional Studies | Biomarkers, Tumor - analysis | Cadherins - analysis | Tumor Burden | Metaplasia | Neoplasms, Complex and Mixed - chemistry | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Neoplasms, Complex and Mixed - pathology | Biomarkers, Tumor - genetics | Mutation | Neurofibromin 1 - genetics | ErbB Receptors - analysis | Enrichment | Cytokeratin | Prognosis | Mesenchyme | p53 Protein | Guidelines | Metastases | Consortia | Breast carcinoma | Bioindicators | Indicators | Sequences | Epidermal growth factor receptors | Invasiveness | Case reports | Breast cancer | Morphology | Medical prognosis | Neurofibromatosis | Biomarkers | Diagnostic systems | PTEN protein | Tumors | Cancer | Index Medicus
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3. Full Text Whole-genome landscapes of major melanoma subtypes
by Hayward, Nicholas K and Hayward, Nicholas K and Wilmott, James S and Wilmott, James S and Waddell, Nicola and Waddell, Nicola and Johansson, Peter A and Johansson, Peter A and Field, Matthew A and Field, Matthew A and Nones, Katia and Nones, Katia and Patch, Ann-Marie and Patch, Ann-Marie and Kakavand, Hojabr and Kakavand, Hojabr and Alexandrov, Ludmil B and Alexandrov, Ludmil B and Burke, Hazel and Burke, Hazel and Jakrot, Valerie and Jakrot, Valerie and Kazakoff, Stephen and Kazakoff, Stephen and Holmes, Oliver and Holmes, Oliver and Leonard, Conrad and Leonard, Conrad and Sabarinathan, Radhakrishnan and Sabarinathan, Radhakrishnan and Mularoni, Loris and Mularoni, Loris and Wood, Scott and Wood, Scott and Xu, Qinying and Xu, Qinying and Waddell, Nick and Waddell, Nick and Tembe, Varsha and Tembe, Varsha and Pupo, Gulietta M and Pupo, Gulietta M and De Paoli-Iseppi, Ricardo and De Paoli-Iseppi, Ricardo and Vilain, Ricardo E and Vilain, Ricardo E and Shang, Ping and Shang, Ping and Lau, Loretta M S and Lau, Loretta M. S and Dagg, Rebecca A and Dagg, Rebecca A and Schramm, Sarah-Jane and Schramm, Sarah-Jane and Pritchard, Antonia and Pritchard, Antonia and Dutton-Regester, Ken and Dutton-Regester, Ken and Newell, Felicity and Newell, Felicity and Fitzgerald, Anna and Fitzgerald, Anna and Shang, Catherine A and Shang, Catherine A and Grimmond, Sean M and Grimmond, Sean M and Pickett, Hilda A and Pickett, Hilda A and Yang, Jean Y and Yang, Jean Y and Stretch, Jonathan R and Stretch, Jonathan R and Behren, Andreas and Behren, Andreas and Kefford, Richard F and Kefford, Richard F and Hersey, Peter and Hersey, Peter and Long, Georgina V and Long, Georgina V and Cebon, Jonathan and Cebon, Jonathan and Shackleton, Mark and Shackleton, Mark and Spillane, Andrew J and Spillane, Andrew J and Saw, Robyn P. M and Saw, Robyn P M and López-Bigas, Núria and López-Bigas, Núria and Pearson, John V and Pearson, John V and Thompson, John F and Thompson, John F and Scolyer, Richard A and Scolyer, Richard A and Mann, Graham J and Mann, Graham J and Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Nature (London), ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 175 - 180
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Membrane Proteins - genetics | Humans | X-linked Nuclear Protein | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Mutation - genetics | Genes, p16 | Genome, Human - genetics | Tumor Suppressor Protein p53 - genetics | Ultraviolet Rays - adverse effects | Telomerase - genetics | Signal Transduction - drug effects | GTP Phosphohydrolases - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Mitogen-Activated Protein Kinases - genetics | Neurofibromatosis 1 - genetics | Melanoma - classification | Nuclear Proteins - genetics | DNA Helicases - genetics | Telomere - genetics | Genetic research | Genetic aspects | Genomes | Research | Melanoma | Pathogenesis | Copy number | Mucosa | p53 Protein | Radiation | Security | Epidemiology | Metastases | Scholarships & fellowships | Reproduction (copying) | Coding | Mismatch repair | Clusters | Eye (anatomy) | Deoxyribonucleic acid--DNA | Medical research | Breakpoints | Radiation effects | MAP kinase | Exposure | Sun | Amplification | Bridges | Pathology | Ultraviolet radiation | Mutagenesis | Computation | Skin | Mutation | Internet | Aberration | Biotechnology | Genes | DNA damage | Carcinogens | Infrastructure | Signatures | Health | U.V. radiation | Inversions | Foldback | Data processing | Energy policy | Readers | Deamination | Protein kinase | Cell lines | Gene mapping | Tumors | Cancer | Index Medicus | Biological Science | 60 APPLIED LIFE SCIENCES
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4. Full Text Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis
by Nones, Katia and Waddell, Nicola and Wayte, Nicci and Patch, Ann-Marie and Bailey, Peter and Newell, Felicity and Holmes, Oliver and Fink, J. Lynn and Quinn, Michael C. J and Tang, Yue Hang and Lampe, Guy and Quek, Kelly and Loffler, Kelly A and Manning, Suzanne and Idrisoglu, Senel and Miller, David and Xu, Qinying and Waddell, Nick and Wilson, Peter J and Bruxner, Timothy J. C and Christ, Angelika N and Harliwong, Ivon and Nourse, Craig and Nourbakhsh, Ehsan and Anderson, Matthew and Kazakoff, Stephen and Leonard, Conrad and Wood, Scott and Simpson, Peter T and Reid, Lynne E and Krause, Lutz and Hussey, Damian J and Watson, David I and Lord, Reginald V and Nancarrow, Derek and Phillips, Wayne A and Gotley, David and Smithers, B. Mark and Whiteman, David C and Hayward, Nicholas K and Campbell, Peter J and Pearson, John V and Grimmond, Sean M and Barbour, Andrew P
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5224 - 5224
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Carcinogenesis - pathology | Adenocarcinoma - pathology | Esophageal Neoplasms - genetics | Chromosomes, Human - genetics | Humans | Carcinogenesis - genetics | Adenocarcinoma - genetics | Gene Rearrangement - genetics | Mutation - genetics | Chromosome Breakage | Genome, Human - genetics | Esophageal Neoplasms - pathology | Index Medicus
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5. Full Text Genome‐wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT‐ROBO, ITGA2 and MET signaling
by Nones, Katia and Waddell, Nic and Song, Sarah and Patch, Ann‐Marie and Miller, David and Johns, Amber and Wu, Jianmin and Kassahn, Karin S and Wood, David and Bailey, Peter and Fink, Lynn and Manning, Suzanne and Christ, Angelika N and Nourse, Craig and Kazakoff, Stephen and Taylor, Darrin and Leonard, Conrad and Chang, David K and Jones, Marc D and Thomas, Michelle and Watson, Clare and Pinese, Mark and Cowley, Mark and Rooman, Ilse and Pajic, Marina and Butturini, Giovanni and Malpaga, Anna and Corbo, Vincenzo and Crippa, Stefano and Falconi, Massimo and Zamboni, Giuseppe and Castelli, Paola and Lawlor, Rita T and Gill, Anthony J and Scarpa, Aldo and Pearson, John V and Biankin, Andrew V and Grimmond, Sean M and APGI
International journal of cancer, ISSN 0020-7136, 09/2014, Volume 135, Issue 5, pp. 1110 - 1118
SLIT‐ROBO pathway | stellate cell activation | pancreatic cancer | axon‐guidance | methylation | SLIT-ROBO pathway | axon-guidance | Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Tumors | Epigenesis, Genetic | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Pancreatic Ducts - pathology | Integrins - metabolism | Promoter Regions, Genetic - genetics | Carcinoma, Pancreatic Ductal - genetics | RNA, Messenger - biosynthesis | DNA Methylation | Wnt Proteins - genetics | Base Sequence | Aged, 80 and over | Adult | Female | Pancreatic Stellate Cells - pathology | Cell Adhesion - genetics | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Pancreatic Neoplasms - genetics | Signal Transduction - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Proto-Oncogene Proteins c-met - genetics | Transforming Growth Factor beta - genetics | Integrin alpha2 - genetics | Aged | Receptors, Immunologic - genetics | Epigenetic inheritance | RNA | Genomics | Genomes | Gene expression | Promoters (Genetics) | Analysis | Pancreatic cancer | DNA | Genetic research | Bone morphogenetic proteins | Genetic aspects | Methylation | Integrins | Cancer | DNA methylation | Epigenetics | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance
by Saunus, Jodi M and Quinn, Michael CJ and Patch, Ann‐Marie and Pearson, John V and Bailey, Peter J and Nones, Katia and McCart Reed, Amy E and Miller, David and Wilson, Peter J and Al‐Ejeh, Fares and Mariasegaram, Mythily and Lau, Queenie and Withers, Teresa and Jeffree, Rosalind L and Reid, Lynne E and Da Silva, Leonard and Matsika, Admire and Niland, Colleen M and Cummings, Margaret C and Bruxner, Timothy JC and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wani, Shivangi and Anderson, Matthew J and Fink, J Lynn and Holmes, Oliver and Kazakoff, Stephen and Leonard, Conrad and Newell, Felicity and Taylor, Darrin and Waddell, Nick and Wood, Scott and Xu, Qinying and Kassahn, Karin S and Narayanan, Vairavan and Taib, Nur Aishah and Teo, Soo‐Hwang and Chow, Yock Ping and kConFab and Jat, Parmjit S and Brandner, Sebastian and Flanagan, Adrienne M and Khanna, Kum Kum and Chenevix‐Trench, Georgia and Grimmond, Sean M and Simpson, Peter T and Waddell, Nicola and Lakhani, Sunil R and KConFab
The Journal of pathology, ISSN 0022-3417, 11/2015, Volume 237, Issue 3, pp. 363 - 378
RNA sequencing | targeted therapy | exome sequencing | brain metastasis | genomic signature | HER2 | HER3 | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Receptor, ErbB-4 - metabolism | Predictive Value of Tests | Phosphorylation | Receptor, ErbB-3 - metabolism | Receptor, ErbB-2 - genetics | Humans | Gene Expression Regulation, Neoplastic | Receptor, ErbB-2 - metabolism | Tumor Microenvironment | Molecular Targeted Therapy | Brain Neoplasms - secondary | DNA Mutational Analysis | Biomarkers, Tumor - metabolism | Genomics - methods | Precision Medicine | Brain Neoplasms - enzymology | Genetic Predisposition to Disease | Genetic Association Studies | Brain Neoplasms - genetics | Gene Expression Profiling - methods | Gene Dosage | Receptor, ErbB-3 - genetics | Brain Neoplasms - drug therapy | Phenotype | Gene Amplification | Protein Kinase Inhibitors - therapeutic use | Ligands | Biomarkers, Tumor - genetics | Receptor, ErbB-4 - genetics | Enzyme Activation | Mutation | Genetic research | Brain | Metastasis | Genomics | Index Medicus
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