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International Journal of Epidemiology, ISSN 0300-5771, 07/2019
Journal Article
International journal of epidemiology, 07/2019
BACKGROUNDEvidence concerning the potential repurposing of antihypertensives for Alzheimer's disease prevention is inconclusive. We used Mendelian... 
Index Medicus
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 06/2019, Volume 69, Issue 4, pp. 1067 - 1075
Background: Low participation in clinical trials is a major challenge to advancing clinical Alzheimer’s disease (AD) research and care. Factors influencing... 
Medical research | Embedded systems | Radar | Angiotensin | Clinical trials | Embedding | Diagnostic systems | Recording | Patients | Alzheimer's disease | Recruitment
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1659 - P1659
Journal Article
Acta Neuropathologica Communications, ISSN 2051-5960, 12/2019, Volume 7, Issue 1, pp. 1 - 3
Fluorogenic activity following ACE1 cleavage was measured by addition of C-domain or N-domain FRET substrates (Abz-LFK (DnP)-OH trifluoroacetate salt)... 
Hypertension | Pathology | Enzymes | Hypotheses | Brain research | Peptides | Neuropathology | Research & development--R&D | Alzheimers disease | Age | Dementia | Angiotensin-II converting enzyme-1 (ACE1) | Alzheimer’s disease | Renin-angiotensin system | Anti-hypertensives
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P749 - P749
Journal Article
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, ISSN 0305-1846, 06/2015, Volume 41, Issue 4, pp. 428 - 444
Journal Article
by Hollingworth, P and Harold, D and Sims, R and Gerrish, A and Lambert, J.C and Carrasquillo, M.M and Abraham, R and Hamshere, M.L and Pahwa, J.S and Moskvina, V and Dowzell, K and Jones, N and Stretton, A and Thomas, C and Richards, A and Ivanov, D and Widdowson, C and Chapman, J and Lovestone, S and Powell, J and Proitsi, P and Lupton, M.K and Brayne, C and Rubinsztein, D.C and Gill, M and Lawlor, B and Lynch, A and Brown, K.S and Passmore, P.A and Craig, D and McGuinness, B and Todd, S and Holmes, C and Mann, D and Smith, A.D and Beaumont, H and Warden, D and Wilcock, G and Love, S and Kehoe, P.G and Hooper, N.M and Vardy, E.R.L.C and Hardy, J and Mead, S and Fox, N.C and Rossor, M and Collinge, J and Maier, W and Jessen, F and Ruther, E and Schurmann, B and Heun, R and Kolsch, H and van den Bussche, H and Heuser, I and Kornhuber, J and Wiltfang, J and Dichgans, M and Frolich, L and Hampel, H and Gallacher, J and Hull, M and Rujescu, D and Giegling, I and Goate, A.M and Kauwe, J.S.K and Cruchaga, C and Nowotny, P and Morris, J.C and Mayo, K and Sleegers, K and Bettens, K and Engelborghs, S and de Deyn, P.P and Van Broeckhoven, C and Livingston, G and Bass, N.J and Gurling, H and McQuillin, A and Gwilliam, R and Deloukas, P and Al-Chalabi, A and Shaw, C.E and Tsolaki, M and Singleton, A.B and Guerreiro, R and Muhleisen, T. W and Nothen, M. M and Moebus, S and Jockel, K.H and Klopp, N and Wichmann, H. E and Pankratz, V.S and Sando, S.B and Aasly, J.O and Barcikowska, M and Wszolek, Z.K and Dickson, D.W and Graff-Radford, N.R. and others and Alzheimer's Dis Neuroimaging and EADI1 Consortium and CHARGE Consortium and Alzheimer's Disease Neuroimaging Initiative and EADI1 consortium and CHARGE consortium and the Alzheimer's Disease Neuroimaging Initiative
Nature Genetics, ISSN 1061-4036, 2011, Volume 43, Issue 5, pp. 429 - 435
Journal Article
Brain Pathology, ISSN 1015-6305, 04/2008, Volume 18, Issue 2, p. 239
Journal Article
Brain Pathology, ISSN 1015-6305, 04/2008, Volume 18, Issue 2, pp. 239 - 239
Journal Article
by Deloukas, Panagiotis and Hamshere, Marian L and Lovestone, Simon and Mead, Simon and Nöthen, Markus M and Gerrish, Amy and O'Donovan, Michael and Hüll, Michael and Hardy, John and Hampel, Harald and Passmore, Peter A and Engelborghs, Sebastiaan and Abraham, Richard and Thomas, Charlene and Moskvina, Valentina and Brayne, Carol and Lawlor, Brian and Bass, Nicholas J and McQuillin, Andrew and Holmans, Peter A and Jones, Nicola and Pahwa, Jaspreet Singh and Morgan, Kevin and Klopp, Norman and Schürmann, Britta and Carrasquillo, Minerva M and Jessen, Frank and Tsolaki, Magda and McGuinness, Bernadette and Van Broeckhoven, Christine and De Deyn, Peter P and Cruchaga, Carlos and Mayo, Kevin and Wichmann, H-Erich and Brown, Kristelle S and Fox, Nick and Proitsi, Petroula and Mühleisen, Thomas W and Lupton, Michelle K and Lynch, Aoibhinn and Williams, Julie and Singleton, Andrew B and Moebus, Susanne and Dowzell, Kimberley and Livingston, Gill and Powell, John and Todd, Stephen and Wiltfang, Jens and Kornhuber, Johannes and Shaw, Christopher E and Pankratz, V Shane and Owen, Michael J and Holmes, Clive and Kehoe, Patrick G and Al-Chalabi, Ammar and Morgan, Angharad R and Heuser, Isabella and Williams, Amy and Mann, David and Gurling, Hugh and Kauwe, John S K and Goate, Alison M and Frölich, Lutz and Rubinsztein, David C and Love, Seth and Rossor, Martin and Rujescu, Dan and Hollingworth, Paul and Bettens, Karolien and Younkin, Steven G and Nowotny, Petra and Dichgans, Martin and Smith, A David and Collinge, John and van den Bussche, Hendrik and Gwilliam, Rhian and Guerreiro, Rita and Jöckel, Karl-Heinz and Sims, Rebecca and Morris, John C and Gill, Michael and Craig, David and Sleegers, Kristel and Harold, Denise and Stretton, Alexandra and Maier, Wolfgang
Nature Genetics, ISSN 1061-4036, 10/2009, Volume 41, Issue 10, pp. 1088 - 1093
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 01/2013, Volume 33, Issue 1, pp. 95 - 110
Vascular deposition of amyloid- (A) leads to the death of cerebrovascular smooth muscle cells (CVSMCs) in cerebral amyloid angiopathy (CAA). Apolipoprotein E... 
Journal Article
by Cruchaga, Carlos and Karch, Celeste M and Jin, Sheng Chih and Benitez, Bruno A and Cai, Yefei and Guerreiro, Rita and Harari, Oscar and Norton, Joanne and Budde, John and Bertelsen, Sarah and Jeng, Amanda T and Cooper, Breanna and Skorupa, Tara and Carrell, David and Levitch, Denise and Hsu, Simon and Choi, Jiyoon and Ryten, Mina and Hardy, John and Trabzuni, Daniah and Weale, Michael E and Ramasamy, Adaikalavan and Smith, Colin and Sassi, Celeste and Bras, Jose and Gibbs, J. Raphael and Hernandez, Dena G and Lupton, Michelle K and Powell, John and Forabosco, Paola and Ridge, Perry G and Corcoran, Christopher D and Tschanz, Joann T and Norton, Maria C and Munger, Ronald G and Schmutz, Cameron and Leary, Maegan and Demirci, F. Yesim and Bamne, Mikhil N and Wang, Xingbin and Lopez, Oscar L and Ganguli, Mary and Medway, Christopher and Turton, James and Lord, Jenny and Braae, Anne and Barber, Imelda and Brown, Kristelle and Passmore, Peter and Craig, David and Johnston, Janet and McGuinness, Bernadette and Todd, Stephen and Heun, Reinhard and Kölsch, Heike and Kehoe, Patrick G and Hooper, Nigel M and Vardy, Emma R.L.C and Mann, David M and Pickering-Brown, Stuart and Kalsheker, Noor and Lowe, James and Morgan, Kevin and David Smith, A and Wilcock, Gordon and Warden, Donald and Holmes, Clive and Pastor, Pau and Lorenzo-Betancor, Oswaldo and Brkanac, Zoran and Scott, Erick and Topol, Eric and Rogaeva, Ekaterina and Singleton, Andrew B and Kamboh, M. Ilyas and St George-Hyslop, Peter and Cairns, Nigel and Morris, John C and Kauwe, John S. K and Goate, Alison M and Alzheimers Res UK ARUK Consortium and UKBEC and Alzheimer's Research UK (ARUK) Consortium
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7484, pp. 550 - 554
Journal Article
by Jones, Lesley and Holmans, Peter A and Hamshere, Marian L and Harold, Denise and Moskvina, Valentina and Ivanov, Dobril and Pocklington, Andrew and Abraham, Richard and Hollingworth, Paul and Sims, Rebecca and Gerrish, Amy and Pahwa, Jaspreet Singh and Jones, Nicola and Stretton, Alexandra and Morgan, Angharad R and Lovestone, Simon and Powell, John and Proitsi, Petroula and Lupton, Michelle K and Brayne, Carol and Rubinsztein, David C and Gill, Michael and Lawlor, Brian and Lynch, Aoibhinn and Morgan, Kevin and Brown, Kristelle S and Passmore, Peter A and Craig, David and Mcguinness, Bernadette and Todd, Stephen and Holmes, Clive and Mann, David and Smith, A. David and Love, Seth and Kehoe, Patrick G and Mead, Simon and Fox, Nick and Rossor, Martin and Collinge, John and Maier, Wolfgang and Jessen, Frank and Schürmann, Britta and van den Bussche, Hendrik and Heuser, Isabella and Peters, Oliver and Kornhuber, Johannes and Wiltfang, Jens and Dichgans, Martin and Frölich, Lutz and Harald, Hampel and Hüll, Michael and Rujescu, Dan and Goate, Alison M and Kauwe, John S. K and Cruchaga, Carlos and Nowotny, Petra and Morris, John C and Mayo, Kevin and Livingston, Gill and Bass, Nicholas J and Gurling, Hugh and Mcquillin, Andrew and Gwilliam, Rhian and Deloukas, Panos and Al-Chalabi, Ammar and Shaw, Christopher E and Singleton, Andrew B and Guerreiro, Rita and Mühleisen, Thomas W and Nöthen, Markus M and Moebus, Susanne and Jöckel, Karl-Heinz and Klopp, Norman and Wichmann, H.-Erich and Rüther, Eckhard and Carrasquillo, Minerva M and Pankratz, V. Shane and Younkin, Steven G and Hardy, John and O'Donovan, Michael C and Owen, Michael J and Williams, Julie
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e13950 - e13950
Journal Article