Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 4, pp. 894 - 901.e5
Background IgE sensitization against grass pollen is a cause of seasonal allergic rhinitis. Objective We sought to investigate the evolution at the molecular...
Allergy and Immunology | Allergenic molecules | component-resolved therapy | Phleum pratense | children | prediction | Phl p 1 | timothy grass | allergic rhinitis | component-resolved diagnosis | immunoglobulin E | grass pollen | hay fever | Allergic rhinitis | Component-resolved therapy | Prediction | Grass pollen | Immunoglobulin E | Timothy grass | Children | Component-resolved diagnosis | Hay fever | GRASS-POLLEN ALLERGENS | DIAGNOSIS | EFFICACY | PREVALENCE | IMMUNOLOGY | CHILDHOOD | RHINITIS | ALLERGY | IMMUNOTHERAPY | ASTHMA | EXTRACT | Predictive Value of Tests | Prospective Studies | Humans | Child, Preschool | Female | Infant | Male | Phleum - immunology | Child | Immunoglobulin E - blood | Cohort Studies | Rhinitis, Allergic, Seasonal - immunology | Consulting services | Universities and colleges | Disease | Patients | Allergies | Age | Questionnaires | Serum levels | Inventories | Hypersensitivity | Spreading | Evolution | Pollen | Grasses
Allergy and Immunology | Allergenic molecules | component-resolved therapy | Phleum pratense | children | prediction | Phl p 1 | timothy grass | allergic rhinitis | component-resolved diagnosis | immunoglobulin E | grass pollen | hay fever | Allergic rhinitis | Component-resolved therapy | Prediction | Grass pollen | Immunoglobulin E | Timothy grass | Children | Component-resolved diagnosis | Hay fever | GRASS-POLLEN ALLERGENS | DIAGNOSIS | EFFICACY | PREVALENCE | IMMUNOLOGY | CHILDHOOD | RHINITIS | ALLERGY | IMMUNOTHERAPY | ASTHMA | EXTRACT | Predictive Value of Tests | Prospective Studies | Humans | Child, Preschool | Female | Infant | Male | Phleum - immunology | Child | Immunoglobulin E - blood | Cohort Studies | Rhinitis, Allergic, Seasonal - immunology | Consulting services | Universities and colleges | Disease | Patients | Allergies | Age | Questionnaires | Serum levels | Inventories | Hypersensitivity | Spreading | Evolution | Pollen | Grasses
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 6, pp. 1535 - 1546
Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. More than...
Allergy and Immunology | Allergy | National Heart, Lung, and Blood Institute (NHLBI) | Mechanisms of the Development of Allergy (MeDALL) | asthma | birth cohorts | National Institute of Allergy and Infectious Disease (NIAID) | WHEEZING RHINOVIRUS ILLNESSES | EARLY-LIFE | LUNG-FUNCTION | IMMUNOLOGY | CHILDHOOD ASTHMA | PRESCHOOL-CHILDREN | AIRWAY RESPONSIVENESS | ATOPIC DISEASES | EXHALED NITRIC-OXIDE | 1ST 6 YEARS | YOUNG-CHILDREN | Asthma - diagnosis | Phenotype | National Heart, Lung, and Blood Institute (U.S.) | Hypersensitivity - etiology | United States | Humans | Risk Factors | Hypersensitivity - diagnosis | Asthma - etiology | National Institute of Allergy and Infectious Diseases (U.S.) | Asthma | Studies | Drug therapy | Allergies | Al·lèrgia | Asma | Anafilaxi | MeDALL | NHLBI | NIAID
Allergy and Immunology | Allergy | National Heart, Lung, and Blood Institute (NHLBI) | Mechanisms of the Development of Allergy (MeDALL) | asthma | birth cohorts | National Institute of Allergy and Infectious Disease (NIAID) | WHEEZING RHINOVIRUS ILLNESSES | EARLY-LIFE | LUNG-FUNCTION | IMMUNOLOGY | CHILDHOOD ASTHMA | PRESCHOOL-CHILDREN | AIRWAY RESPONSIVENESS | ATOPIC DISEASES | EXHALED NITRIC-OXIDE | 1ST 6 YEARS | YOUNG-CHILDREN | Asthma - diagnosis | Phenotype | National Heart, Lung, and Blood Institute (U.S.) | Hypersensitivity - etiology | United States | Humans | Risk Factors | Hypersensitivity - diagnosis | Asthma - etiology | National Institute of Allergy and Infectious Diseases (U.S.) | Asthma | Studies | Drug therapy | Allergies | Al·lèrgia | Asma | Anafilaxi | MeDALL | NHLBI | NIAID
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 6, pp. 1528 - 1536.e13
Background The causal link between body mass index (BMI) or obesity and asthma in children is still being debated. Analyses of large longitudinal studies with...
Allergy and Immunology | Body mass index | European birth cohorts | Global Allergy and Asthma European Network | rapid growth | asthma | latent growth mixture model | child | LUNG-FUNCTION | RISK | IMMUNOLOGY | CHILDREN | OBESITY | ALLERGY | OVERWEIGHT | GROWTH | ATOPIC DISEASES | ADIPOSITY | WEIGHT | ASSOCIATION | Body Mass Index | Asthma - complications | Obesity - complications | Humans | Risk Factors | Child, Preschool | Female | Infant | Male | Child | Infant, Newborn | Asthma - epidemiology | Universities and colleges | Asthma in children | Analysis | Public health | Environmental health | Studies | Ethics | Councils | Population | Birth weight | Obstetrics | Age | Asthma
Allergy and Immunology | Body mass index | European birth cohorts | Global Allergy and Asthma European Network | rapid growth | asthma | latent growth mixture model | child | LUNG-FUNCTION | RISK | IMMUNOLOGY | CHILDREN | OBESITY | ALLERGY | OVERWEIGHT | GROWTH | ATOPIC DISEASES | ADIPOSITY | WEIGHT | ASSOCIATION | Body Mass Index | Asthma - complications | Obesity - complications | Humans | Risk Factors | Child, Preschool | Female | Infant | Male | Child | Infant, Newborn | Asthma - epidemiology | Universities and colleges | Asthma in children | Analysis | Public health | Environmental health | Studies | Ethics | Councils | Population | Birth weight | Obstetrics | Age | Asthma
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 5, pp. 1426 - 1433.e12
Background Studies of a limited number of allergens suggested that nonsensitized children produce IgG responses mainly to foodborne allergens, whereas...
Allergy and Immunology | Allergenic molecules | microarray | childhood | birth cohort | IgE | IgG | prediction | IgG4 | IgE sensitization
Allergy and Immunology | Allergenic molecules | microarray | childhood | birth cohort | IgE | IgG | prediction | IgG4 | IgE sensitization
Journal Article
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Full Text
Early-life determinants of asthma from birth to age 20 years: A German birth cohort study
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 4, pp. 979 - 988.e3
Background The lack of longitudinal data analyses from birth to adulthood is hampering long-term asthma prevention strategies. Objective We aimed to determine...
Allergy and Immunology | risk factors | hypersensitivity | survival analysis | immunization | epidemiologic factors | Infant | adolescent | preschool | heredity | child | FOLLOW-UP | IMMUNOLOGY | GENE-ENVIRONMENT INTERACTIONS | CHILDHOOD ASTHMA | PRESCHOOL-CHILDREN | RISK-FACTOR | ALLERGY | SENSITIZATION | TOBACCO-SMOKE | MATERNAL SMOKING | SOCIOECONOMIC-STATUS | EXPOSURE | Follow-Up Studies | Humans | Risk Factors | Proportional Hazards Models | Child, Preschool | Male | Patient Outcome Assessment | Germany - epidemiology | Incidence | Pregnancy | Young Adult | Adolescent | Female | Asthma - etiology | Child | Infant, Newborn | Asthma - epidemiology | Cohort Studies | Prevention | Information management | Analysis | Asthma | Studies | Variables | Immunization | Disease | Socioeconomic factors | Families & family life | Standard deviation | Allergies | Age
Allergy and Immunology | risk factors | hypersensitivity | survival analysis | immunization | epidemiologic factors | Infant | adolescent | preschool | heredity | child | FOLLOW-UP | IMMUNOLOGY | GENE-ENVIRONMENT INTERACTIONS | CHILDHOOD ASTHMA | PRESCHOOL-CHILDREN | RISK-FACTOR | ALLERGY | SENSITIZATION | TOBACCO-SMOKE | MATERNAL SMOKING | SOCIOECONOMIC-STATUS | EXPOSURE | Follow-Up Studies | Humans | Risk Factors | Proportional Hazards Models | Child, Preschool | Male | Patient Outcome Assessment | Germany - epidemiology | Incidence | Pregnancy | Young Adult | Adolescent | Female | Asthma - etiology | Child | Infant, Newborn | Asthma - epidemiology | Cohort Studies | Prevention | Information management | Analysis | Asthma | Studies | Variables | Immunization | Disease | Socioeconomic factors | Families & family life | Standard deviation | Allergies | Age
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 126, Issue 6, pp. 1170 - 1175.e2
Background Rhinitis in older children and adults has been shown to be a predictor for adolescent- and adult-onset asthma. These findings suggest an interaction...
Allergy and Immunology | birth cohort study | risk factors | wheezing | Allergic rhinitis | allergic sensitization | BRONCHIAL HYPERRESPONSIVENESS | RISK-FACTORS | PERSISTENT ASTHMA | FOLLOW-UP | IMMUNOLOGY | HAY-FEVER | CHILDHOOD | AIRWAY DISEASE | ALLERGY | 1ST 6 YEARS | BIRTH COHORT | LIFE | Rhinitis, Allergic, Seasonal - physiopathology | Prognosis | Follow-Up Studies | Humans | Risk Factors | Child, Preschool | Infant | Male | Rhinitis, Allergic, Seasonal - diagnosis | Immunoglobulin E - blood | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - epidemiology | Adolescent | Age of Onset | Female | Population | Respiratory Sounds | Child | Early Diagnosis | Germany | Infant, Newborn | Rhinitis | Asthma in children | Children | Families & family life | Multivariate analysis | Allergies | Age | Children & youth | Asthma | Milk
Allergy and Immunology | birth cohort study | risk factors | wheezing | Allergic rhinitis | allergic sensitization | BRONCHIAL HYPERRESPONSIVENESS | RISK-FACTORS | PERSISTENT ASTHMA | FOLLOW-UP | IMMUNOLOGY | HAY-FEVER | CHILDHOOD | AIRWAY DISEASE | ALLERGY | 1ST 6 YEARS | BIRTH COHORT | LIFE | Rhinitis, Allergic, Seasonal - physiopathology | Prognosis | Follow-Up Studies | Humans | Risk Factors | Child, Preschool | Infant | Male | Rhinitis, Allergic, Seasonal - diagnosis | Immunoglobulin E - blood | Rhinitis, Allergic, Seasonal - immunology | Rhinitis, Allergic, Seasonal - epidemiology | Adolescent | Age of Onset | Female | Population | Respiratory Sounds | Child | Early Diagnosis | Germany | Infant, Newborn | Rhinitis | Asthma in children | Children | Families & family life | Multivariate analysis | Allergies | Age | Children & youth | Asthma | Milk
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 643 - 654.e6
Background The nature of allergens and route and dose of exposure may affect the natural development of IgE and IgG responses. Objective We sought to...
Allergy and Immunology | epidemiology | MeDALL | microarray | IgE | allergen components | IgG | food allergens | cohort | respiratory allergens | EGEA | BRONCHIAL HYPERRESPONSIVENESS | POLLEN ALLERGENS | ENVIRONMENT | IMMUNOLOGY | MAJOR ALLERGEN | BIRCH | ALLERGY | SENSITIZATION | IMMUNOTHERAPY | CAT | ASTHMA | IMMUNOGLOBULIN-G | Asthma - diagnosis | France - epidemiology | Immunization | Skin Tests | Cross-Sectional Studies | Follow-Up Studies | Immunoglobulin G - blood | Humans | Middle Aged | Male | Immunoglobulin E - blood | Cross Reactions | Environmental Exposure - adverse effects | Allergens - immunology | Asthma - immunology | Adult | Female | Asthma - epidemiology | Cohort Studies | Immunoglobulin E | Allergy | Allergens | Allergic reaction | Epidemiology | Immunoglobulin G | Analysis | Studies | Immunoglobulins | ISO standards | Population | Pollen | Allergies | Asthma | Food | Food allergens | Allergen components | Respiratory allergens | Cohort | Microarray | Life Sciences | Allergology | Immunology
Allergy and Immunology | epidemiology | MeDALL | microarray | IgE | allergen components | IgG | food allergens | cohort | respiratory allergens | EGEA | BRONCHIAL HYPERRESPONSIVENESS | POLLEN ALLERGENS | ENVIRONMENT | IMMUNOLOGY | MAJOR ALLERGEN | BIRCH | ALLERGY | SENSITIZATION | IMMUNOTHERAPY | CAT | ASTHMA | IMMUNOGLOBULIN-G | Asthma - diagnosis | France - epidemiology | Immunization | Skin Tests | Cross-Sectional Studies | Follow-Up Studies | Immunoglobulin G - blood | Humans | Middle Aged | Male | Immunoglobulin E - blood | Cross Reactions | Environmental Exposure - adverse effects | Allergens - immunology | Asthma - immunology | Adult | Female | Asthma - epidemiology | Cohort Studies | Immunoglobulin E | Allergy | Allergens | Allergic reaction | Epidemiology | Immunoglobulin G | Analysis | Studies | Immunoglobulins | ISO standards | Population | Pollen | Allergies | Asthma | Food | Food allergens | Allergen components | Respiratory allergens | Cohort | Microarray | Life Sciences | Allergology | Immunology
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 2, pp. 371 - 377
Background Atopic dermatitis (AD) is a common inflammatory skin disease. Previous studies have revealed shared genetic determinants among different...
Allergy and Immunology | persistent atopic dermatitis | soluble IL-6 receptor | Atopic dermatitis | inflammation | single nucleotide polymorphism | longitudinal study | population-based cohort | prognosis | candidate association study | genetic risk factor | PATHWAYS | FOLLOW-UP | MECHANISMS | IMMUNOLOGY | CHILDHOOD | CHILDREN | ALLERGY | DISEASE | ASTHMA | MUTATIONS | BIRTH COHORT | ASSOCIATION | Dermatitis, Atopic - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Interleukin-6 - genetics | Receptors, Interleukin-6 - genetics | Humans | Risk Factors | Child, Preschool | Genotype | Infant | Male | Adolescent | Alleles | Female | Polymorphism, Single Nucleotide | Receptors, Interleukin-6 - blood | Child | Interleukin-6 - metabolism | Infant, Newborn | Cohort Studies | Risk factors | Genes | Independent study | Population | Age | Immune system | Asthma | Meta-analysis
Allergy and Immunology | persistent atopic dermatitis | soluble IL-6 receptor | Atopic dermatitis | inflammation | single nucleotide polymorphism | longitudinal study | population-based cohort | prognosis | candidate association study | genetic risk factor | PATHWAYS | FOLLOW-UP | MECHANISMS | IMMUNOLOGY | CHILDHOOD | CHILDREN | ALLERGY | DISEASE | ASTHMA | MUTATIONS | BIRTH COHORT | ASSOCIATION | Dermatitis, Atopic - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Interleukin-6 - genetics | Receptors, Interleukin-6 - genetics | Humans | Risk Factors | Child, Preschool | Genotype | Infant | Male | Adolescent | Alleles | Female | Polymorphism, Single Nucleotide | Receptors, Interleukin-6 - blood | Child | Interleukin-6 - metabolism | Infant, Newborn | Cohort Studies | Risk factors | Genes | Independent study | Population | Age | Immune system | Asthma | Meta-analysis
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 4, pp. 932 - 940.e12
Background Allergic rhinitis (AR) is one of the most common chronic diseases, usually starting in the first 2 decades of life. Information on predictors, risk,...
Allergy and Immunology | risk factors | survival analysis | preschool child | epidemiologic factors | primary prevention | Infant | adolescent | heredity | ECZEMA | ADOLESCENCE | IMMUNOLOGY | CHILDHOOD | CHILDREN | IMPACT | ALLERGY | DISEASE | ASTHMA | NONALLERGIC RHINITIS | NATURAL COURSE | MATERNAL SMOKING | Asthma - diagnosis | Prognosis | Prospective Studies | Asthma - prevention & control | Follow-Up Studies | Humans | Risk Factors | Child, Preschool | Rhinitis, Allergic - diagnosis | Young Adult | Rhinitis, Allergic - prevention & control | Allergens - immunology | Time Factors | Adolescent | Sex Factors | Adult | Seasons | Child | Germany | Infant, Newborn | Cohort Studies | Prevention | Chronic diseases | Travel | Rhinitis | Analysis | Pregnancy | Ear diseases | Behavior | Family medical history | Allergies | Age
Allergy and Immunology | risk factors | survival analysis | preschool child | epidemiologic factors | primary prevention | Infant | adolescent | heredity | ECZEMA | ADOLESCENCE | IMMUNOLOGY | CHILDHOOD | CHILDREN | IMPACT | ALLERGY | DISEASE | ASTHMA | NONALLERGIC RHINITIS | NATURAL COURSE | MATERNAL SMOKING | Asthma - diagnosis | Prognosis | Prospective Studies | Asthma - prevention & control | Follow-Up Studies | Humans | Risk Factors | Child, Preschool | Rhinitis, Allergic - diagnosis | Young Adult | Rhinitis, Allergic - prevention & control | Allergens - immunology | Time Factors | Adolescent | Sex Factors | Adult | Seasons | Child | Germany | Infant, Newborn | Cohort Studies | Prevention | Chronic diseases | Travel | Rhinitis | Analysis | Pregnancy | Ear diseases | Behavior | Family medical history | Allergies | Age
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 129, Issue 4, pp. 943 - 954.e4
Mechanisms of the Development of Allergy (MeDALL), a Seventh Framework Program European Union project, aims to generate novel knowledge on the mechanisms of...
Allergy and Immunology | Allergy | Mechanisms of the Development of Allergy | asthma | phenotypes | IgE | Seventh Framework Program | SEVERE ASTHMA | BRONCHIAL HYPERRESPONSIVENESS | DIAGNOSTIC GATEKEEPERS | LUNG-FUNCTION | IMMUNOLOGY | WORLD-HEALTH-ORGANIZATION | CLUSTER-ANALYSIS | T-REGULATORY-CELLS | KNOWLEDGE MANAGEMENT | 1ST 6 YEARS | SYSTEMS BIOLOGY | Epigenesis, Genetic | Humans | Risk Factors | Child, Preschool | Hypersensitivity - immunology | Research | Young Adult | Phenotype | Animals | Immunoglobulin E - immunology | Adolescent | Hypersensitivity - genetics | Hypersensitivity - epidemiology | Child | Medical colleges | Immunoglobulins | Lung diseases | Immunoglobulin E | Respiratory agents | Allergic reaction | Biometry | Asthma | Respiratory tract diseases | Genetic aspects | Skin | Universities and colleges | Public health | Cluster analysis | Disease | Eczema | Classification | Statistical methods | Gender differences | Drug dosages | Allergies | Children & youth
Allergy and Immunology | Allergy | Mechanisms of the Development of Allergy | asthma | phenotypes | IgE | Seventh Framework Program | SEVERE ASTHMA | BRONCHIAL HYPERRESPONSIVENESS | DIAGNOSTIC GATEKEEPERS | LUNG-FUNCTION | IMMUNOLOGY | WORLD-HEALTH-ORGANIZATION | CLUSTER-ANALYSIS | T-REGULATORY-CELLS | KNOWLEDGE MANAGEMENT | 1ST 6 YEARS | SYSTEMS BIOLOGY | Epigenesis, Genetic | Humans | Risk Factors | Child, Preschool | Hypersensitivity - immunology | Research | Young Adult | Phenotype | Animals | Immunoglobulin E - immunology | Adolescent | Hypersensitivity - genetics | Hypersensitivity - epidemiology | Child | Medical colleges | Immunoglobulins | Lung diseases | Immunoglobulin E | Respiratory agents | Allergic reaction | Biometry | Asthma | Respiratory tract diseases | Genetic aspects | Skin | Universities and colleges | Public health | Cluster analysis | Disease | Eczema | Classification | Statistical methods | Gender differences | Drug dosages | Allergies | Children & youth
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