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Journal of Clinical Pathology, ISSN 0021-9746, 11/2018, Volume 71, Issue 11, pp. 957 - 962
Cyclin-dependent kinase 12 (CDK12) belongs to the cyclin-dependent kinase (CDK) family of serine/threonine protein kinases that regulate transcriptional and... 
breast cancer | cancer genetics | cell biology | C-MYC oncogene | ovarian cancer | RNA-POLYMERASE-II | COMPLEX | PHOSPHORYLATION | DNA-DAMAGE RESPONSE | KINASE | PATHOLOGY | MESSENGER-RNA | SYNTHETIC LETHALITY | C-TERMINAL DOMAIN | MUTATIONS | EXPRESSION | Proteins | Phosphorylation | Genomics | Genes | Cyclin-dependent kinases | DNA damage | Cell cycle | Amino acids | Genomes | Kinases | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Carcinogenesis, ISSN 0143-3334, 12/2005, Volume 26, Issue 12, pp. 2031 - 2045
Journal Article
GENETICS, ISSN 0016-6731, 07/2019, Volume 212, Issue 3, pp. 655 - 665
Microsatellite sequences have an enhanced susceptibility to mutation, and can act as sentinels indicating elevated mutation rates and increased risk of cancer.... 
REPAIR DEFICIENCY | mouse | mutation | HOMEOSTASIS | intestine | INSTABILITY | Msh2 | PD-1 BLOCKADE | GENETICS & HEREDITY | microsatellite | CANCER | Microsatellites | Change detection | Mitosis | Cloning | Colorectal cancer | MSH2 protein | Health risks | Homeostasis | Cell division | Mutation rates | Epithelium | Loci | Intestine | Crypts | Stem cells | Mutation | Genetic testing | Bioinformatics | Age | Deoxyribonucleic acid--DNA | Investigations
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 11/2017, Volume 24, Issue 11, pp. 1853 - 1860
Ionizing radiation (IR) is one of the most widely used treatments for cancer. However, acute damage to the gastrointestinal tract or gastrointestinal acute... 
GASTROINTESTINAL-SYNDROME | STRAND BREAK REPAIR | P53-DEFICIENT MICE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | MITOTIC CATASTROPHE | DEPENDENT PROTEIN-KINASE | SMALL-INTESTINE | CHECKPOINT ACTIVATION | IONIZING-RADIATION | REPLICATION STRESS | CELL BIOLOGY | Stem Cell Niche - radiation effects | Receptors, G-Protein-Coupled - metabolism | Apoptosis - radiation effects | Mitosis | Gastrointestinal Tract - radiation effects | Stem Cells - metabolism | Gastrointestinal Tract - pathology | DNA-Binding Proteins - metabolism | Radiation Tolerance - radiation effects | Acute Radiation Syndrome - pathology | DNA-Activated Protein Kinase - metabolism | Acute Radiation Syndrome - metabolism | Inhibitor of Apoptosis Proteins - metabolism | Repressor Proteins - metabolism | Radiation, Ionizing | Paneth Cells - metabolism | Mice, Inbred C57BL | Stem Cells - radiation effects | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Survivin | Mitotic Index | Phenotype | Phosphorylation - radiation effects | Animals | Staining and Labeling | Stem Cells - pathology | DNA Damage | Histones - metabolism | Cell Proliferation - radiation effects | Cell proliferation | Animal models | Radiosensitivity | Epithelial cells | p53 Protein | DNA damage | DNA repair | Ionizing radiation | Intestine | Rodents | Cell cycle | Repair | Deoxyribonucleic acid--DNA | I.R. radiation | Gastrointestinal tract | Paneth cells | DNA-dependent protein kinase | Cell death | Stem cells | Tumor suppressor genes | Sensitivity enhancement | Mutation | Radiation damage | Tumors | Apoptosis | Cancer | Original Paper
Journal Article
by Fan, Qiao and Verhoeven, Virginie and Wojciechowski, Robert and Barathi, Veluchamy and Hysi, Pirro and Guggenheim, Jean and Höhn, René and Vitart, Veronique and Khawaja, Anthony P and Yamashiro, Kenji and Hosseini, S Mohsen and Lehtimäki, Terho and Lu, Yi and Haller, Toomas and Xie, Jing and Delcourt, Cécile and Pirastu, Mario and Wedenoja, Juho and Gharahkhani, Puya and Venturini, Cristina and Miyake, Masahiro and Hewit, Alex and Guo, Xiaobo and Mazur, Johanna and Huffman, Jenifer E and Williams, Katie M and Polasek, Ozren and Campbell, Harry and Rudan, Igor and Vatavuk, Zoran and Wilson, James F and Joshi, Peter and Mcmahon, George and St Pourcain, Beate and Evans, David and Simpson, Claire and Schwantes-An, Tae-Hwi and Igo, Robert and Mirshahi, Alireza and Cougnard-Grégoire, Auey and Bellenguez, Céline and Blettner, Maria and Raitakari, Olli and Kähönen, Mika and Seppälä, Ilkka and Zeller, Tanja and Meitinger, Thomas and Ried, Janina and Gieger, Christian and Portas, Laura and Leeuwen, Elisa and Amin, Najaf and Uitterlinden, Ané and Rivadeneira Ramirez, Fernando and Hofman, Albert and Vingerling, Hans and Wang, Ying and Wang, Xu and Tai-Hui Boh, Eileen and Ikram, Kamran and Sabanayagam, Charumathi and Gupta, Preeti and Tan, Vincent and Zhou, Lei and Ho, Candice E. H and Lim, Wan'E and Beuerman, Roger W and Siantar, Rosalynn and Tai, E-Shyong and Vithana, Eranga and Mihailov, Evelin and Khor, C.C and Hayward, Caroline and Luben, Robert and Foster, Paul and Klein, Barbara and Klein, Ronald and Wong, Hoi-Suen and Mitchell, Paul and Metspalu, Anes and Aung, Tin and Young, Terri L and He, Mingguang and Pärssinen, Olavi and Duijn, Cornelia and Jin Wang, Jie and Williams, Cathy and Jonas, Jost B and Teo, Yik Ying and Mackey, David and Oexle, Konrad and Yoshimura, N and Paterson, Anew D and Pfeiffer, Norbert and Wong, Tien Yin and Baird, Paul and Stambolian, Dwight and Wilson, Joan E. Bailey and Cheng, Ching-Yu and Hammond, Christopher J and ... and Consortium Refractive Error Myopia and Consortium for Refractive Error and Myopia and Consortium for Refractive Error and Myopia (CREAM)
Nature Communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, p. 11008
Journal Article
by Vos, Theo and Barber, Ryan M and Bell, Michelle L and Bell, Brad and Bertozzi-Villa, Amelia and Biryukov, Stan and Bolliger, Ian and Charlson, Fiona and Davis, Adrian and Degenhardt, Louisa and Dicker, Daniel and Duan, Leilei and Erskine, Holly and Feigin, Valery L and Ferrari, Alize J and Fitzmaurice, Christina and Fleming, Thomas and Graetz, Nicholas and Guinovart, Caterina and Haagsma, Juanita and Hansen, Gillian M and Hanson, Sarah Wulf and Heuton, Kyle R and Higashi, Hideki and Kassebaum, Nicholas and Kyu, Hmwe and Laurie, Evan and Liang, Xiofeng and Lofgren, Katherine and Lozano, Rafael and MacIntyre, Michael F and Moradi-Lakeh, Maziar and Naghavi, Mohsen and Naghavi, Paria and Nguyen, Grant and Odell, Shaun and Ortblad, Katrina and Roberts, David Allen and Roth, Gregory A and Sandar, Logan and Serina, Peter T and Stanaway, Jeffrey D and Steiner, Timothy J and Steiner, Caitlyn and Thomas, Elissa and Thomas, Bernadette and Vollset, Stein Emil and Whiteford, Harvey and Wolock, Timothy M and Ye, Pengpeng and Zhou, Maigeng and Ãvila, Marco A and Aasvang, Gunn Marit and Abbafati, Cristiana and Ozgoren, Ayse Abbasoglu and Abd-Allah, Foad and Aziz, Muna I Abdel and Abera, Semaw F and Aboyans, Victor and Abraham, Biju and Abraham, Jerry P and Abubakar, Ibrahim and Abu-Raddad, Laith J and Abu-Rmeileh, Niveen ME and Aburto, Tania C and Achoki, Tom and Ackerman, Ilana N and Adelekan, Ademola and Ademi, Zanfina and Adou, Arsène K and Adsuar, Josef C and Arnlov, Johan and Agardh, Emilie E and Al Khabouri, Mazin J and Alam, Sayed Saidul and Alasfoor, Deena and Albittar, Mohammed I and Alegretti, Miguel A and Aleman, Alicia V and Alemu, Zewdie A and Alfonso-Cristancho, Rafael and Alhabib, Samia and Ali, Raghib and Alla, Francois and Allebeck, Peter and Allen, Peter J and AlMazroa, Mohammad AbdulAziz and Alsharif, Ubai and Alvarez, Elena and Alvis-Guzman, Nelson and Ameli, Omid and Amini, Heresh and Ammar, Walid and Anderson, Benjamin O and Anderson, H. Ross and Antonio, Carl Abelardo T and Anwari, Palwasha and Apfel, Henry and Arsenijevic, Valentain S Arsic and Artaman, Al and ... and Global Burden Dis Study and Global Burden of Disease Study 2013 Collaborators and Mittuniversitetet and Fakulteten för humanvetenskap and Avdelningen för psykologi
The Lancet, ISSN 0140-6736, 08/2015, Volume 386, Issue 9995, pp. 743 - 800
Summary Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an... 
Internal Medicine | CUTANEOUS LEISHMANIASIS | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | OTITIS-MEDIA | CONDUCT DISORDER | MENTAL-DISORDERS | WEIGHTS | IRON-DEFICIENCY | ALCOHOL DEPENDENCE | EPIDEMIOLOGY | HEALTH OUTCOMES | POPULATION | MEDICINE, GENERAL & INTERNAL | RISK | OSTEOARTHRITIS | Age Distribution | Prevalence | Developing Countries - statistics & numerical data | Humans | Middle Aged | Child, Preschool | Cost of Illness | Infant | Male | Wounds and Injuries - epidemiology | Developed Countries - statistics & numerical data | Incidence | Young Adult | Global Health - statistics & numerical data | Aged, 80 and over | Neglected Diseases - epidemiology | Adult | Disabled Persons - statistics & numerical data | Female | Child | Infant, Newborn | Chronic Disease - epidemiology | Residence Characteristics - statistics & numerical data | Adolescent | Sex Distribution | Acute Disease - epidemiology | Aged | Medicine, Experimental | Chronic diseases | Medical research | Analysis | Prevalence studies (Epidemiology) | Headache | Disease | Mental disorders | Disorders | Mental depression | Epidemiology | Pain | Mathematical analysis | Upgrading | Human immunodeficiency virus--HIV | Trends | Injuries | Age | Injury analysis | Global health | Population growth | Comorbidity | Health | Mortality | Regression analysis | Estimates | Neurological diseases | Charities | Infectious diseases | Respiratory diseases | Residence Characteristics | Neglected Diseases | Life Sciences | Acute Disease | Global Health | Developed Countries | Wounds and Injuries | Santé publique et épidémiologie | Developing Countries | Chronic Disease | Disabled Persons | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences | Nutrition and Disease | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | VLAG | HNE Voeding en Ziekte
Journal Article