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Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S169 - S170
Chimeric antigen receptor (CAR) T-cells targeting CD19 have led to complete response (CR) rates of 70-90% in children and adults with refractory/relapsed... 
Antimitotic agents | Antigens | Care and treatment | Acute lymphocytic leukemia | T cells | Antineoplastic agents | Drug approval | Cancer
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2016, Volume 126, Issue 10, pp. 3814 - 3826
Potent CD19-directed immunotherapies, such as chimeric antigen receptor T cells (CART) and blinatumomab, have drastically changed the outcome of patients with... 
CHIMERIC RECEPTORS | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | EFFECTOR FUNCTIONS | B-CELL | ACUTE-LYMPHOBLASTIC-LEUKEMIA | IN-VIVO | ALPHA CHAIN | ACUTE MYELOID-LEUKEMIA | BLINATUMOMAB | RECEPTOR T-CELLS | Immunotherapy - methods | Interleukin-3 Receptor alpha Subunit - administration & dosage | Neoplasm Recurrence, Local - prevention & control | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Drug Resistance, Neoplasm | Antineoplastic Agents - administration & dosage | Mice, SCID | T-Lymphocytes - transplantation | Xenograft Model Antitumor Assays | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Animals | Neoplastic Stem Cells - metabolism | Cell Line, Tumor | Receptors, Antigen, T-Cell - administration & dosage | Mice, Inbred NOD | T-Lymphocytes - immunology | Antigens, CD19 - metabolism | Interleukin-3 Receptor alpha Subunit - metabolism | Antigen-antibody reactions | Cellular proteins | Care and treatment | Immunotherapy | Patient outcomes | Development and progression | Genetic aspects | Acute lymphocytic leukemia | Properties | Health aspects | Methods | Antigens | Pediatrics | Medical research | Flow cytometry | Immunoglobulins | Leukemia | Colleges & universities | Clinical trials | T cell receptors | Experiments | Cancer therapies | Patients | Genotype & phenotype | Institutional repositories | Lymphocytes | Medical prognosis | Response rates | Stem cells | Laboratory animals | Tumors | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 4575 - 4575
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S193 - S194
Herein, we re-examine these findings with a larger cohort and longer follow-up. We also compare the composite endpoint graft-versus-host disease (GVHD)-free,... 
Journal Article
Blood, ISSN 0006-4971, 04/2017, Volume 129, Issue 17, pp. 2395 - 2407
We and others previously reported potent antileukemia efficacy of CD123-redirected chimeric antigen receptor (CAR) T cells in preclinical human acute myeloid... 
MULTIPLE-MYELOMA | GEMTUZUMAB OZOGAMICIN | THERAPY | B-CELL | SAFETY | ACUTE LYMPHOBLASTIC-LEUKEMIA | INTERNATIONAL EXPERT PANEL | IN-VIVO | HEMATOLOGY | SUICIDE-GENE | GROUP TRIAL AAML0531 | Recombinant Fusion Proteins - immunology | RNA, Messenger - immunology | Humans | Male | Transplantation, Heterologous | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | Leukemia, Myeloid, Acute - immunology | Lymphocyte Depletion | T-Lymphocytes - transplantation | Lentivirus - metabolism | CD3 Complex - genetics | T-Lymphocytes - drug effects | Antibodies, Monoclonal, Humanized - pharmacology | Female | Lentivirus - genetics | Receptors, Antigen, T-Cell - immunology | Leukemia, Myeloid, Acute - therapy | Antigens, CD20 - immunology | Gene Expression | Immunotherapy, Adoptive - methods | Genetic Vectors - chemistry | Leukemia, Myeloid, Acute - pathology | RNA, Messenger - genetics | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Genetic Vectors - metabolism | Hematopoietic Stem Cell Transplantation | RNA, Antisense - immunology | Treatment Outcome | Alemtuzumab | Remission Induction | Antigens, CD20 - genetics | Rituximab - pharmacology | Xenograft Model Antitumor Assays | Animals | T-Lymphocytes - cytology | Interleukin-3 Receptor alpha Subunit - genetics | Interleukin-3 Receptor alpha Subunit - immunology | CD3 Complex - immunology | Recombinant Fusion Proteins - genetics | Mice, Inbred NOD | T-Lymphocytes - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Interleukin-3 Receptor alpha Subunit - antagonists & inhibitors | Leukemia, Myeloid, Acute - genetics | RNA, Antisense - genetics | Index Medicus | Abridged Index Medicus | Immunobiology
Journal Article
Haematologica, ISSN 0390-6078, 06/2019, p. haematol.2019.224121
The natural history, prognostication and optimal treatment of Richter transformation developed from chronic lymphocytic leukemia (CLL) are not well defined. We... 
Journal Article
Cancer Discovery, ISSN 2159-8274, 10/2017, Volume 7, Issue 10, pp. 1154 - 1167
Patients with otherwise treatment-resistant Hodgkin lymphoma could benefi t from chimeric antigen receptor T-cell (CART) therapy. However, Hodgkin lymphoma... 
INTERLEUKIN-3 RECEPTOR | REED-STERNBERG CELLS | STEM-CELLS | B-CELL | ONCOLOGY | MACROPHAGES | ACUTE LYMPHOBLASTIC-LEUKEMIA | IN-VIVO | ALPHA CHAIN | DISEASE | ACUTE MYELOID-LEUKEMIA | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 05/2018, Volume 173, Issue 6, pp. 1439 - 1453.e19
Journal Article
Journal Article
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, ISSN 1940-087X, 07/2019, Issue 149
Chimeric antigen receptor T (CAR-T) cell therapy is a cutting edge and potentially revolutionary new treatment option for cancer. However, there are... 
knockout | Issue 149 | THERAPY | CRISPR/Cas9 | GM-CSF | MULTIDISCIPLINARY SCIENCES | Cancer Research | chimeric antigen receptor T cell | CAR-T cell | gene editing | Index Medicus
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2017, Volume 23, Issue 3, pp. S247 - S248
Journal Article
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