Diabetes Research and Clinical Practice, ISSN 0168-8227, 09/2019, Volume 155, p. 107750
To calculate process quality measures of diabetes care in Japan using nationwide exclusive claims database. Using the National Database of health insurance...
Diabetes | Claims data | Japan | Quality of care | Health services research | UNITED-STATES | DISEASE | ENDOCRINOLOGY & METABOLISM | ADULTS | HEALTH-INSURANCE CLAIMS | OF-CARE | GUIDELINE
Diabetes | Claims data | Japan | Quality of care | Health services research | UNITED-STATES | DISEASE | ENDOCRINOLOGY & METABOLISM | ADULTS | HEALTH-INSURANCE CLAIMS | OF-CARE | GUIDELINE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2007, Volume 104, Issue 15, pp. 6478 - 6483
Understanding plant metabolism as an integrated system is essential for metabolic engineering aimed at the effective production of compounds useful to human...
Cell culture techniques | Transcription factors | Databases | Genes | Cell lines | Glucosinolates | Biosynthesis | Indoles | Plants | Sulfur | Transcriptomics | Functional genomics | Coexpression | NETWORK | SECONDARY METABOLISM | CHAIN ELONGATION PATHWAY | MULTIDISCIPLINARY SCIENCES | functional genomics | ELEMENTS | METABOLOMICS | DATABASE | INTEGRATION | THALIANA | PART | transcriptomics | GENE-EXPRESSION | coexpression | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Glucosinolates - biosynthesis | Transcription Factors - metabolism | Arabidopsis Proteins - genetics | Biosynthetic Pathways - genetics | Histone Acetyltransferases | Models, Biological | Mass Spectrometry | Chromatography, Liquid | Proteomics - methods | Transcription Factors - genetics | Genetic aspects | Research | Gene expression | Arabidopsis | Biological Sciences
Cell culture techniques | Transcription factors | Databases | Genes | Cell lines | Glucosinolates | Biosynthesis | Indoles | Plants | Sulfur | Transcriptomics | Functional genomics | Coexpression | NETWORK | SECONDARY METABOLISM | CHAIN ELONGATION PATHWAY | MULTIDISCIPLINARY SCIENCES | functional genomics | ELEMENTS | METABOLOMICS | DATABASE | INTEGRATION | THALIANA | PART | transcriptomics | GENE-EXPRESSION | coexpression | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Glucosinolates - biosynthesis | Transcription Factors - metabolism | Arabidopsis Proteins - genetics | Biosynthetic Pathways - genetics | Histone Acetyltransferases | Models, Biological | Mass Spectrometry | Chromatography, Liquid | Proteomics - methods | Transcription Factors - genetics | Genetic aspects | Research | Gene expression | Arabidopsis | Biological Sciences
Journal Article
Journal of Gastroenterology, ISSN 0944-1174, 4/2016, Volume 51, Issue 4, pp. 370 - 379
Type 2 diabetes mellitus (T2DM) is an established independent risk factor for hepatocellular carcinoma (HCC). T2DM is associated with non-alcoholic...
Medicine & Public Health | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | PNPLA3 | Hepatocellular carcinoma | Type 2 diabetes mellitus | Surgical Oncology | JAZF1 | RISK-FACTORS | VARIANTS | FATTY LIVER-DISEASE | SUSCEPTIBILITY | POLYMORPHISM | NEPHROPATHY | GENE | GLUCOSE | PROSTATE-CANCER | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Membrane Proteins - genetics | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Middle Aged | Risk Factors | Genotype | Male | Hepatitis - complications | Liver Neoplasms - etiology | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Aged, 80 and over | Female | Liver Neoplasms - pathology | Aged | Carcinoma, Hepatocellular - etiology | Polymorphism, Single Nucleotide | Neoplasm Proteins - genetics | Diabetes Mellitus, Type 2 - complications | Lipase - genetics | Type 2 diabetes | Hepatitis | Single nucleotide polymorphisms | Hepatoma
Medicine & Public Health | Colorectal Surgery | Hepatology | Gastroenterology | Abdominal Surgery | PNPLA3 | Hepatocellular carcinoma | Type 2 diabetes mellitus | Surgical Oncology | JAZF1 | RISK-FACTORS | VARIANTS | FATTY LIVER-DISEASE | SUSCEPTIBILITY | POLYMORPHISM | NEPHROPATHY | GENE | GLUCOSE | PROSTATE-CANCER | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Membrane Proteins - genetics | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Middle Aged | Risk Factors | Genotype | Male | Hepatitis - complications | Liver Neoplasms - etiology | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - pathology | Aged, 80 and over | Female | Liver Neoplasms - pathology | Aged | Carcinoma, Hepatocellular - etiology | Polymorphism, Single Nucleotide | Neoplasm Proteins - genetics | Diabetes Mellitus, Type 2 - complications | Lipase - genetics | Type 2 diabetes | Hepatitis | Single nucleotide polymorphisms | Hepatoma
Journal Article
Metabolomics, ISSN 1573-3882, 4/2013, Volume 9, Issue 2, pp. 444 - 453
Metabolic microenvironment of tumor cells is influenced by oncogenic signaling and tissue-specific metabolic demands, blood supply, and enzyme expression. To...
Life Sciences | Biochemistry, general | Metabolomics | CE-MS | Phosphoproteomics | Tumor microenvironment | Lung cancer | Molecular Medicine | Developmental Biology | Prostate cancer | Biomedicine general | Cell Biology | CANCER-CELLS | SYSTEM | PHOSPHORYLATION SITES | PYRUVATE-DEHYDROGENASE | FUMARATE REDUCTASE | PEPTIDES | ENDOCRINOLOGY & METABOLISM | ENRICHMENT | METAL-OXIDE CHROMATOGRAPHY | PROTEOMICS | KINASES | Lactates | Glucose metabolism | Enzymes | Squamous cell carcinoma | Metabolites | Branched chain amino acids | Analysis | Electrophoresis | Universities and colleges | Mass spectrometry | Tumors | Original
Life Sciences | Biochemistry, general | Metabolomics | CE-MS | Phosphoproteomics | Tumor microenvironment | Lung cancer | Molecular Medicine | Developmental Biology | Prostate cancer | Biomedicine general | Cell Biology | CANCER-CELLS | SYSTEM | PHOSPHORYLATION SITES | PYRUVATE-DEHYDROGENASE | FUMARATE REDUCTASE | PEPTIDES | ENDOCRINOLOGY & METABOLISM | ENRICHMENT | METAL-OXIDE CHROMATOGRAPHY | PROTEOMICS | KINASES | Lactates | Glucose metabolism | Enzymes | Squamous cell carcinoma | Metabolites | Branched chain amino acids | Analysis | Electrophoresis | Universities and colleges | Mass spectrometry | Tumors | Original
Journal Article
American Journal of Kidney Diseases, ISSN 0272-6386, 2009, Volume 53, Issue 6, pp. 982 - 992
Background Estimation of glomerular filtration rate (GFR) is limited by differences in creatinine generation among ethnicities. Our previously reported...
Nephrology | inulin clearance | Japanese | serum creatinine | Glomerular filtration rate | SKELETAL-MUSCLE MASS | COCKCROFT-GAULT EQUATIONS | RENAL-DISEASE | GLOMERULAR-FILTRATION-RATE | US POPULATION | DIET | NUTRITION EXAMINATION SURVEY | 3RD NATIONAL-HEALTH | UROLOGY & NEPHROLOGY | CHRONIC KIDNEY-DISEASE | CHINESE PATIENTS | Kidney Diseases - physiopathology | Japan - epidemiology | Reproducibility of Results | Prospective Studies | Cross-Sectional Studies | Humans | Middle Aged | Kidney Function Tests - methods | Male | Glomerular Filtration Rate - physiology | Kidney Diseases - ethnology | Kidney Function Tests - standards | Kidney Diseases - epidemiology | Adolescent | Aged, 80 and over | Creatinine - blood | Adult | Female | Aged | Japan - ethnology
Nephrology | inulin clearance | Japanese | serum creatinine | Glomerular filtration rate | SKELETAL-MUSCLE MASS | COCKCROFT-GAULT EQUATIONS | RENAL-DISEASE | GLOMERULAR-FILTRATION-RATE | US POPULATION | DIET | NUTRITION EXAMINATION SURVEY | 3RD NATIONAL-HEALTH | UROLOGY & NEPHROLOGY | CHRONIC KIDNEY-DISEASE | CHINESE PATIENTS | Kidney Diseases - physiopathology | Japan - epidemiology | Reproducibility of Results | Prospective Studies | Cross-Sectional Studies | Humans | Middle Aged | Kidney Function Tests - methods | Male | Glomerular Filtration Rate - physiology | Kidney Diseases - ethnology | Kidney Function Tests - standards | Kidney Diseases - epidemiology | Adolescent | Aged, 80 and over | Creatinine - blood | Adult | Female | Aged | Japan - ethnology
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A14579 - A14579
ObjectiveTo estimate the proportion of not recognizing hypercholesterolemia and/or medication among adult statin users in the US and to examine the...
Journal Article
GENES, ISSN 2073-4425, 09/2019, Volume 10, Issue 9, p. 715
The OTOA gene (Locus: DFNB22) is reported to be one of the causative genes for non-syndromic autosomal recessive hearing loss. The copy number variations...
VARIANTS | IDENTIFICATION | IMPAIRMENT | FAMILY | OTOA | PATHOGENICITY | SEQUENCE | GENES | GENETICS & HEREDITY | hearing loss | MUTATIONS | SPECTRUM | copy number variations | DFNB22
VARIANTS | IDENTIFICATION | IMPAIRMENT | FAMILY | OTOA | PATHOGENICITY | SEQUENCE | GENES | GENETICS & HEREDITY | hearing loss | MUTATIONS | SPECTRUM | copy number variations | DFNB22
Journal Article
Science, ISSN 0036-8075, 7/2003, Volume 301, Issue 5631, pp. 376 - 379
We collected and completely sequenced 28,469 full-length complementary DNA clones from Oryza sativa L. ssp. japonica cv. Nipponbare. Through homology searches...
Transcription factors | Complementary DNA | Exons | Genomics | Genes | Genetic loci | Reports | Genomes | Open reading frames | Sequencing | Rice | DRAFT SEQUENCE | DATABASE | RNA | MULTIDISCIPLINARY SCIENCES | Protein Structure, Tertiary | Amino Acid Sequence | Transcription Factors - chemistry | Alternative Splicing | Genes, Plant | Plant Proteins - physiology | Open Reading Frames | Computational Biology | Molecular Sequence Data | Genome, Plant | Transcription Factors - genetics | Sequence Analysis, DNA | Sequence Homology, Nucleic Acid | Sequence Homology, Amino Acid | Plant Proteins - genetics | Oryza - genetics | Plant Proteins - chemistry | Databases, Protein | Cloning, Molecular | Transcription, Genetic | Databases, Nucleic Acid | DNA, Complementary | RNA, Antisense - genetics | Proteins | Cloning | Deoxyribonucleic acid--DNA
Transcription factors | Complementary DNA | Exons | Genomics | Genes | Genetic loci | Reports | Genomes | Open reading frames | Sequencing | Rice | DRAFT SEQUENCE | DATABASE | RNA | MULTIDISCIPLINARY SCIENCES | Protein Structure, Tertiary | Amino Acid Sequence | Transcription Factors - chemistry | Alternative Splicing | Genes, Plant | Plant Proteins - physiology | Open Reading Frames | Computational Biology | Molecular Sequence Data | Genome, Plant | Transcription Factors - genetics | Sequence Analysis, DNA | Sequence Homology, Nucleic Acid | Sequence Homology, Amino Acid | Plant Proteins - genetics | Oryza - genetics | Plant Proteins - chemistry | Databases, Protein | Cloning, Molecular | Transcription, Genetic | Databases, Nucleic Acid | DNA, Complementary | RNA, Antisense - genetics | Proteins | Cloning | Deoxyribonucleic acid--DNA
Journal Article
The Plant Journal, ISSN 0960-7412, 06/2005, Volume 42, Issue 5, pp. 641 - 651
Summary Rice (Oryza sativa L.) plants possess three homologous but distinct genes for cytosolic glutamine synthetase (GS1): these are OsGS1;1, OsGS1;2, and...
knockout mutant | retrotransposon Tos17 | cytosolic glutamine synthetase | nitrogen remobilization | rice | Cytosolic glutamine synthetase | Nitrogen remobilization | Retrotransposon Tos17 | Knockout mutant | Rice | ORYZA-SATIVA-L | LEAVES | SYNTHASE PROTEIN | TRANSGENIC PLANTS | PLANT SCIENCES | GENE | NITROGEN | ROOTS | CELLULAR-LOCALIZATION | EXPRESSION | AMMONIUM ASSIMILATION | Multigene Family | Molecular Sequence Data | Gene Expression Profiling | Oryza - enzymology | Plant Proteins - genetics | Oryza - growth & development | Oryza - genetics | Seeds - growth & development | Glutamate-Ammonia Ligase - genetics | Plant Proteins - metabolism | Mutation | Plant Leaves - enzymology | Glutamate-Ammonia Ligase - metabolism
knockout mutant | retrotransposon Tos17 | cytosolic glutamine synthetase | nitrogen remobilization | rice | Cytosolic glutamine synthetase | Nitrogen remobilization | Retrotransposon Tos17 | Knockout mutant | Rice | ORYZA-SATIVA-L | LEAVES | SYNTHASE PROTEIN | TRANSGENIC PLANTS | PLANT SCIENCES | GENE | NITROGEN | ROOTS | CELLULAR-LOCALIZATION | EXPRESSION | AMMONIUM ASSIMILATION | Multigene Family | Molecular Sequence Data | Gene Expression Profiling | Oryza - enzymology | Plant Proteins - genetics | Oryza - growth & development | Oryza - genetics | Seeds - growth & development | Glutamate-Ammonia Ligase - genetics | Plant Proteins - metabolism | Mutation | Plant Leaves - enzymology | Glutamate-Ammonia Ligase - metabolism
Journal Article
Clinical and Experimental Nephrology, ISSN 1342-1751, 6/2015, Volume 19, Issue 3, pp. 379 - 386
Hyperlipidemia is not merely a complication but a major exacerbating factor in longstanding nephrotic syndrome (NS). Low-density lipoprotein apheresis (LDL-A)...
LDL apheresis | Nephrology | Medicine & Public Health | Drug-resistant nephrotic syndrome | Lipid nephrotoxicity | Urology | Short-term results | LDL-APHERESIS | FOCAL GLOMERULOSCLEROSIS | MONOTHERAPY | INJURY | UROLOGY & NEPHROLOGY | HYPERCHOLESTEROLEMIA | CHILDREN | Hypoproteinemia - etiology | Nephrotic Syndrome - urine | Prospective Studies | Humans | Middle Aged | Male | Blood Component Removal | Nephrotic Syndrome - drug therapy | Proteinuria - therapy | Nephrotic Syndrome - complications | Time Factors | Hyperlipidemias - etiology | Adult | Female | Aged | Nephrotic Syndrome - therapy | Hypoproteinemia - therapy | Hyperlipidemias - therapy | Drug Resistance | Lipoproteins, LDL | Proteinuria - etiology | Serum Albumin - metabolism | Nephrotic syndrome | Drug resistance | Health aspects | Analysis | Low density lipoproteins
LDL apheresis | Nephrology | Medicine & Public Health | Drug-resistant nephrotic syndrome | Lipid nephrotoxicity | Urology | Short-term results | LDL-APHERESIS | FOCAL GLOMERULOSCLEROSIS | MONOTHERAPY | INJURY | UROLOGY & NEPHROLOGY | HYPERCHOLESTEROLEMIA | CHILDREN | Hypoproteinemia - etiology | Nephrotic Syndrome - urine | Prospective Studies | Humans | Middle Aged | Male | Blood Component Removal | Nephrotic Syndrome - drug therapy | Proteinuria - therapy | Nephrotic Syndrome - complications | Time Factors | Hyperlipidemias - etiology | Adult | Female | Aged | Nephrotic Syndrome - therapy | Hypoproteinemia - therapy | Hyperlipidemias - therapy | Drug Resistance | Lipoproteins, LDL | Proteinuria - etiology | Serum Albumin - metabolism | Nephrotic syndrome | Drug resistance | Health aspects | Analysis | Low density lipoproteins
Journal Article
Plant and Cell Physiology, ISSN 0032-0781, 2017, Volume 58, Issue 4, pp. 831 - 838
The genus Arthrospira is filamentous, non-nitrogen-fixing cyanobacteria that is commercially important. We identified the molecular structures of carotenoids...
Arthrospira | CruA | Carotenoid | CrtR | Lycopene cyclase | β-Carotene hydroxylase | BACTERIA | crtR | CAROTENOGENESIS | beta-Carotene hydroxylase | BIOSYNTHETIC-PATHWAY | LEVEL | PLANT SCIENCES | CELL BIOLOGY | BETA-CAROTENE | GENOME SEQUENCE | GENE | cruA | SPIRULINA-PLATENSIS | ALGAE | DIVERSITY | Intramolecular Lyases - metabolism | Bacterial Proteins - genetics | Mixed Function Oxygenases - metabolism | beta Carotene - metabolism | Carotenoids - biosynthesis | Zeaxanthins - metabolism | Intramolecular Lyases - genetics | Escherichia coli - genetics | Carotenoids - metabolism | Cloning, Molecular | Bacterial Proteins - metabolism | Spirulina - metabolism | Mixed Function Oxygenases - genetics
Arthrospira | CruA | Carotenoid | CrtR | Lycopene cyclase | β-Carotene hydroxylase | BACTERIA | crtR | CAROTENOGENESIS | beta-Carotene hydroxylase | BIOSYNTHETIC-PATHWAY | LEVEL | PLANT SCIENCES | CELL BIOLOGY | BETA-CAROTENE | GENOME SEQUENCE | GENE | cruA | SPIRULINA-PLATENSIS | ALGAE | DIVERSITY | Intramolecular Lyases - metabolism | Bacterial Proteins - genetics | Mixed Function Oxygenases - metabolism | beta Carotene - metabolism | Carotenoids - biosynthesis | Zeaxanthins - metabolism | Intramolecular Lyases - genetics | Escherichia coli - genetics | Carotenoids - metabolism | Cloning, Molecular | Bacterial Proteins - metabolism | Spirulina - metabolism | Mixed Function Oxygenases - genetics
Journal Article
International Journal of Cardiology, ISSN 0167-5273, 2016, Volume 221, pp. 637 - 641
Abstract Background It remains unknown whether taste disorders can be a risk factor for micro- and macro-vascular diseases in patients with abnormal glucose...
Cardiovascular | Ischemic heart disease | Sweet taste disorder | Sugar intake | Diabetes | Abnormal glucose tolerance | CARDIAC & CARDIOVASCULAR SYSTEMS | PREDICTOR | RISK | RECEPTOR | IMPAIRMENT | DIABETES-MELLITUS | PERCEPTION | OBESITY | POSTPRANDIAL HYPERGLYCEMIA | CARDIOVASCULAR-DISEASE | RETINOPATHY | Glucose Intolerance - epidemiology | Cross-Sectional Studies | Humans | Middle Aged | Taste Disorders - diagnosis | Male | Taste Disorders - epidemiology | Taste Disorders - blood | Vascular Diseases - epidemiology | Vascular Diseases - diagnosis | Glucose Intolerance - blood | Glucose Intolerance - diagnosis | Dietary Sucrose - administration & dosage | Dietary Sucrose - adverse effects | Female | Aged | Nutrition Surveys - trends | Vascular Diseases - blood | Blood circulation disorders | Complications and side effects | Care and treatment | Glucose | Dextrose
Cardiovascular | Ischemic heart disease | Sweet taste disorder | Sugar intake | Diabetes | Abnormal glucose tolerance | CARDIAC & CARDIOVASCULAR SYSTEMS | PREDICTOR | RISK | RECEPTOR | IMPAIRMENT | DIABETES-MELLITUS | PERCEPTION | OBESITY | POSTPRANDIAL HYPERGLYCEMIA | CARDIOVASCULAR-DISEASE | RETINOPATHY | Glucose Intolerance - epidemiology | Cross-Sectional Studies | Humans | Middle Aged | Taste Disorders - diagnosis | Male | Taste Disorders - epidemiology | Taste Disorders - blood | Vascular Diseases - epidemiology | Vascular Diseases - diagnosis | Glucose Intolerance - blood | Glucose Intolerance - diagnosis | Dietary Sucrose - administration & dosage | Dietary Sucrose - adverse effects | Female | Aged | Nutrition Surveys - trends | Vascular Diseases - blood | Blood circulation disorders | Complications and side effects | Care and treatment | Glucose | Dextrose
Journal Article