X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (179) 179
human necessities (133) 133
hygiene (133) 133
medical or veterinary science (133) 133
preparations for medical, dental, or toilet purposes (133) 133
rats (120) 120
chemistry, medicinal (107) 107
humans (100) 100
structure-activity relationship (93) 93
chemistry (78) 78
metallurgy (76) 76
male (75) 75
mice (69) 69
organic chemistry (69) 69
index medicus (67) 67
specific therapeutic activity of chemical compounds ormedicinal preparations (61) 61
heterocyclic compounds (58) 58
rats, sprague-dawley (58) 58
dogs (56) 56
chemistry, organic (55) 55
pharmacology & pharmacy (48) 48
administration, oral (46) 46
biological availability (41) 41
general tagging of cross-sectional technologies spanning over several sections of the ipc (30) 30
general tagging of new technological developments (30) 30
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (30) 30
female (29) 29
molecular structure (26) 26
technical subjects covered by former uspc (26) 26
technical subjects covered by former uspc cross-reference artcollections [xracs] and digests (26) 26
potent (23) 23
dose-response relationship, drug (22) 22
cell line (21) 21
disease models, animal (21) 21
models, molecular (21) 21
stereoisomerism (19) 19
in vitro techniques (17) 17
crystallography, x-ray (16) 16
drug design (16) 16
haplorhini (16) 16
pharmacokinetics (16) 16
pyrrolidines - pharmacology (16) 16
rat (16) 16
ritonavir (16) 16
biochemistry & molecular biology (15) 15
discovery (15) 15
enzyme inhibitors - pharmacology (15) 15
acyclic, carbocyclic or heterocyclic compounds containingelements other than carbon, hydrogen, halogen, oxygen, nitrogen,sulfur, selenium or tellurium (14) 14
area under curve (14) 14
enzyme inhibitors - pharmacokinetics (14) 14
hiv protease inhibitors - pharmacology (14) 14
obesity (14) 14
resistance (14) 14
antineoplastic agents - pharmacology (13) 13
blood pressure - drug effects (13) 13
identification (13) 13
in-vitro (13) 13
ligands (13) 13
macaca fascicularis (13) 13
pyrrolidines - pharmacokinetics (13) 13
analysis (12) 12
endothelin receptor antagonists (12) 12
expression (12) 12
hiv protease inhibitors - pharmacokinetics (12) 12
pain (12) 12
pyridines - pharmacokinetics (12) 12
pyridines - pharmacology (12) 12
receptors, somatostatin - antagonists & inhibitors (12) 12
analgesics - pharmacology (11) 11
binding sites (11) 11
brain - metabolism (11) 11
cancer (11) 11
cell line, tumor (11) 11
derivatives (11) 11
derivatives thereof (11) 11
enzyme inhibitors - chemical synthesis (11) 11
half-life (11) 11
neuropathic pain (11) 11
nucleic acids (11) 11
nucleosides (11) 11
nucleotides (11) 11
pain - drug therapy (11) 11
pyrrolidines - chemistry (11) 11
sugars (11) 11
urea - pharmacology (11) 11
anti-obesity agents - chemical synthesis (10) 10
antineoplastic agents - chemical synthesis (10) 10
drug evaluation, preclinical (10) 10
hiv (10) 10
hiv protease inhibitors - chemical synthesis (10) 10
in-vivo (10) 10
proteases (10) 10
pyrimidines - chemistry (10) 10
receptor, endothelin a (10) 10
urea - analogs & derivatives (10) 10
xenograft model antitumor assays (10) 10
alkyl and aryl transferases - antagonists & inhibitors (9) 9
antagonist (9) 9
antiviral agents (9) 9
binding (9) 9
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
UTL at Downsview - May be requested (11) 11
Online Resources - Online (10) 10
Robarts - Stacks (6) 6
Robarts - May be requested in 6-10 wks (1) 1
Royal Ontario Museum - Far Eastern (1) 1
Royal Ontario Museum - Far Eastern Reference (1) 1
St. Michael's College (John M. Kelly) - 2nd Floor (1) 1
Thomas Fisher Rare Book - Rare Book (1) 1
Trinity College (John W Graham) - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
Victoria University E.J. Pratt - Storage (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (442) 442
French (47) 47
German (23) 23
Spanish (12) 12
Chinese (8) 8
Portuguese (4) 4
Danish (2) 2
Japanese (2) 2
Russian (2) 2
Czech (1) 1
Korean (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Medicine, ISSN 1078-8956, 02/2013, Volume 19, Issue 2, pp. 202 - 208
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2007, Volume 13, Issue 9, pp. 2728 - 2737
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 05/2010, Volume 37, Issue 5, pp. 636 - 640
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 05/2008, Volume 68, Issue 9, pp. 3421 - 3428
Overexpression of the prosurvival Bcl-2 family members (Bcl-2, Bcl-xL, and McI-1) is commonly associated with tumor maintenance, progression, and... 
MULTIPLE-MYELOMA | ONCOLOGY | INDUCED APOPTOSIS | CELL LYMPHOMA | X-L | MCL-1 | NON-HODGKINS-LYMPHOMA | BH3 MIMETIC ABT-737 | PROTEINS | UP-REGULATION | CANCER | Lung Neoplasms - drug therapy | Humans | Lymphoma, Mantle-Cell - pathology | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Antineoplastic Agents - adverse effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Aniline Compounds - administration & dosage | Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications | Antibodies, Monoclonal, Murine-Derived | Administration, Oral | Carcinoma, Small Cell - drug therapy | Cells, Cultured | Lymphoma, Mantle-Cell - drug therapy | Rituximab | Treatment Outcome | Thrombocytopenia - chemically induced | Tumor Burden | Mice, SCID | Mice, Knockout | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Sulfonamides - therapeutic use | Antibodies, Monoclonal - administration & dosage | Models, Biological | Sulfonamides - adverse effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | Aniline Compounds - therapeutic use | Aniline Compounds - adverse effects | Carcinoma, Small Cell - pathology | Neoplasms - pathology | Sulfonamides - administration & dosage | Index Medicus
Journal Article
Journal of Pharmacological and Toxicological Methods, ISSN 1056-8719, 09/2019, Volume 99, p. 106580
DSM421, a dihydroorotate dehydrogenase inhibitor, was in preclinical development as a potential treatment option for malaria. When tested in a core battery of... 
Rat | Cardiovascular | Safety pharmacology | Restraint | Respiratory | DSM421 | Methods | Plethysmography | Stress | Adenosine A3 receptor
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/1998, Volume 42, Issue 12, pp. 3218 - 3224
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/1995, Volume 92, Issue 7, pp. 2484 - 2488
Examination of the structural basis for antiviral activity, oral pharmacokinetics, and hepatic metabolism among a series of symmetry-based inhibitors of the... 
HIV | Humans | Antivirals | Solubility | Rats | Bioavailability | Dosage | Pharmacokinetics | Metabolism | Blood plasma | antiviral | peptidomimetic | acquired immunodeficiency syndrome | C2 SYMMETRICAL INHIBITORS | HIV PROTEASE | THERAPY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PEPTIDOMIMETIC | AIDS | INFECTION | ACQUIRED IMMUNODEFICIENCY SYNDROME | ANTIVIRAL | Drugs | Research | HIV infection | Testing
Journal Article
Journal Article
Journal Article
Science Translational Medicine, ISSN 1946-6234, 2017, Volume 9, Issue 387, pp. eaad9735 - eaad9735
As part of the global effort toward malaria eradication, phenotypic whole-cell screening revealed the 2-aminopyridine class of small molecules as a good... 
MEDICINE, RESEARCH & EXPERIMENTAL | SINGLE-DOSE CURE | IN-VITRO | TRANSMISSION | FALCIPARUM | QUANTIFICATION | DRUG DISCOVERY | KINASE INHIBITORS | DNA-SEQUENCING DATA | MALARIA PARASITES | NEXT-GENERATION | CELL BIOLOGY
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 09/2005, Volume 82, Issue 1, p. 140
A-412997 (2-(3',4',5',6'-tetrahydro-2'H-[2,4'] bipyridinyl-1'-yl)-N-m-tolyl-acetamide) is a highly selective dopamine D.sub.4 receptor agonist that binds with... 
Dopamine | Polybrominated biphenyls | Phenols
Journal Article
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 2005, Volume 82, Issue 1, pp. 140 - 147
A-412997 (2-(3′,4′,5′,6′-tetrahydro-2′ -[2,4′] bipyridinyl-1′-yl)- - -tolyl-acetamide) is a highly selective dopamine D receptor agonist that binds with high... 
Dopamine | A-412997 | Penile erection | D 4 receptor
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 9/2004, Volume 21, Issue 9, pp. 1622 - 1630
Journal Article