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1. Full Text DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice
by Li, Ming-Wen and Lloyd, K. C. Kent
Scientific reports, ISSN 2045-2322, 03/2020, Volume 10, Issue 1, pp. 3833 - 3833
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fertility - genetics | Animals | Sperm Motility - genetics | Cryopreservation | DNA Fragmentation | Mice, Inbred C57BL | Male | Spermatozoa - physiology | Mice | Mutation | Spermatozoa - metabolism | Embryo transfer | Motility | Sperm | Fertility | Morphology | DNA fragmentation | Males | Embryos | Freezing | Deoxyribonucleic acid--DNA | Mutants | Index Medicus
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2. Full Text Mutant twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression
by Song, Lanying and Shan, Yuxi and Kent Lloyd, K.C and Cortopassi, Gino A
Human molecular genetics, ISSN 0964-6906, 12/2012, Volume 21, Issue 23, pp. 5147 - 5158
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | Tyrosine 3-Monooxygenase - metabolism | Substantia Nigra - pathology | Dopaminergic Neurons - pathology | Humans | Mitochondrial Proteins - genetics | Substantia Nigra - metabolism | Behavior, Animal | Cell Respiration - genetics | DNA, Mitochondrial - genetics | Mitochondrial Proteins - metabolism | Dopaminergic Neurons - metabolism | Parkinson Disease - metabolism | Autophagy - genetics | DNA Helicases - genetics | Gene Order | Cell Line | Gene Targeting | Promoter Regions, Genetic | Gene Expression | Ubiquitin-Protein Ligases - metabolism | Mice, Transgenic | Parkinson Disease - genetics | DNA Helicases - metabolism | Tyrosine 3-Monooxygenase - genetics | Animals | Protein Binding | Mice | Mutation | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | Index Medicus
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3. Full Text Efficient mouse genome engineering by CRISPR-EZ technology
by Modzelewski, Andrew J and Chen, Sean and Willis, Brandon J and Lloyd, K.C. Kent and Wood, Joshua A and He, Lin
Nature protocols, ISSN 1754-2189, 06/2018, Volume 13, Issue 6, pp. 1253 - 1274
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | CRISPR-Associated Protein 9 - metabolism | Animals | Zygote | Mice, Inbred C57BL | Microinjections - methods | Clustered Regularly Interspaced Short Palindromic Repeats | Gene Editing - methods | Mice | Electroporation - methods | Mice, Knockout | Genetically modified mice | Restriction enzymes, DNA | Genetic research | Electroporation | Genetic engineering | Research | Methods | CRISPR | Genomes | Ribonucleic acid--RNA | Embryos | Zygotes | Microinjection | Genotyping | Technology | Rodents | Reagents | Mutation | Genetic modification | Index Medicus | zygote | zygote electroporation | sgRNA | RNP | CRISPR-Cas9 | ribonucleoprotein | embryo | Mouse genome editing | Cas9 | electroporation | CRISPR‐EZ
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4. Full Text Disease model discovery from 3,328 gene knockouts by the International Mouse Phenotyping Consortium
by Meehan, Terrence F and Conte, Nathalie and West, David B and Jacobsen, Julius O and Mason, Jeremy and Warren, Jonathan and Chen, Chao-Kung and Tudose, Ilinca and Relac, Mike and Matthews, Peter and Karp, Natasha and Santos, Luis and Fiegel, Tanja and Ring, Natalie and Westerberg, Henrik and Greenaway, Simon and Sneddon, Duncan and Morgan, Hugh and Codner, Gemma F and Stewart, Michelle E and Brown, James and Horner, Neil and Haendel, Melissa and Washington, Nicole and Mungall, Christopher J and Reynolds, Corey L and Gallegos, Juan and Gailus-Durner, Valerie and Sorg, Tania and Pavlovic, Guillaume and Bower, Lynette R and Moore, Mark and Morse, Iva and Gao, Xiang and Tocchini-Valentini, Glauco P and Obata, Yuichi and Cho, Soo Young and Seong, Je Kyung and Seavitt, John and Beaudet, Arthur L and Dickinson, Mary E and Herault, Yann and Wurst, Wolfgang and De Angelis, Martin Hrabe and Kent Lloyd, K.C and Flenniken, Ann M and Nutter, Lauryl M J and Newbigging, Susan and McKerlie, Colin and Justice, Monica J and Murray, Stephen A and Svenson, Karen L and Braun, Robert E and White, Jacqueline K and Bradley, Allan and Flicek, Paul and Wells, Sara and Skarnes, William C and Adams, David J and Parkinson, Helen and Mallon, Ann-Marie and Brown, Steve D.M and Smedley, Damian and Int Mouse Phenotyping Consortium and International Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1231 - 1238
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Phenotype | Animals | Humans | Female | Genetic Diseases, Inborn | Male | Mice | Gene Knockout Techniques | Disease Models, Animal | Mice, Knockout | Usage | Genetic aspects | Research | Animal models in research | Genomics | Heart | Animal models | Ontology | Disease | Genes | Disorders | Genomes | Statistical methods | Gene sequencing | Consortia | Signal transduction | Annotations | Databases | Rodents | Right ventricular dysplasia | Automation | Gene expression | Ventricular dysplasia | Diseases | Studies | Acids | Phenotyping | Diagnostic systems | Mutation | Ventricle | Index Medicus
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5. Full Text Development of outbred CD1 mouse colonies with distinct standardized gut microbiota profiles for use in complex microbiota targeted studies
by Hart, Marcia L and Ericsson, Aaron C and Lloyd, K. C. Kent and Grimsrud, Kristin N and Rogala, Allison R and Godfrey, Virginia L and Nielsen, Judith N and Franklin, Craig L
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 10107 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Animal models | Microbiota | Phenotypes | rRNA 16S | Fecal microflora | Colonies | Genetic crosses | Intestinal microflora | Housing | Embryos | Index Medicus
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6. Full Text Response to "unexpected mutations after CRISPR-Cas9 editing in vivo"
by Nutter, Lauryl M.J and Heaney, Jason D and Kent Lloyd, K.C and Murray, Stephen A and Seavitt, John R and Skarnes, William C and Teboul, Lydia and Brown, Steve D.M and Moore, Mark
Nature methods, ISSN 1548-7091, 04/2018, Volume 15, Issue 4, pp. 235 - 236
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Mutation | Gene Editing | CRISPR-Cas Systems | Clustered Regularly Interspaced Short Palindromic Repeats | Restriction enzymes, DNA | Gene mutations | Nucleotide sequence | Causes of | Physiological aspects | Genetic engineering | Genetic aspects | Health aspects | Methods | CRISPR | Index Medicus
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7. Full Text Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse
by Golub, Mari S and Germann, Stacey L and Lloyd, K.C.Kent
Behavioural brain research, ISSN 0166-4328, 2004, Volume 153, Issue 1, pp. 159 - 170
Cerebellum | Morris maze | erbB4 | Mouse | EGF | Motor activity | Conditional knock-out | Neuregulin | Postnatal development | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Behavioral Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Learning | Behavioral psychophysiology | Miscellaneous | Psychology. Psychoanalysis. Psychiatry | Animal | Psychology. Psychophysiology | Biological and medical sciences | Learning. Memory | Mice, Knockout - genetics | Motor Activity - physiology | Receptor, Epidermal Growth Factor - genetics | Age Factors | Weaning | Nervous System - metabolism | Receptor, Epidermal Growth Factor - deficiency | Male | Psychomotor Performance - physiology | Exploratory Behavior - physiology | RNA, Messenger - biosynthesis | Nervous System - growth & development | Reverse Transcriptase Polymerase Chain Reaction - methods | Female | Mice, Knockout - physiology | Receptor, Epidermal Growth Factor - physiology | Animals, Newborn | Cues | Maze Learning - physiology | Mortality | Behavior, Animal - physiology | Genotype | Neuropsychological Tests | Pregnancy | Animals | Sex Factors | Mice | Body Weight - physiology | Receptor, ErbB-4 | Memory - physiology | Index Medicus
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8. Full Text Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice
by Kwon, Young Sam and Tham, Addy and Lopez, Antonio Jacobo and Edwards, Sydney and Woods, Sean and Chen, Jiajia and Wong-Fortunato, Jenna and Quiroz Alonso, Alejandra and Javier, Seanne and Au, Ingrid and Clarke, Maria and Humpal, Devin and Lloyd, K.C. Kent and Thomasy, Sara and Murphy, Christopher and Glaser, Thomas M and Moshiri, Ala
Developmental biology, ISSN 0012-1606, 02/2020, Volume 458, Issue 2, pp. 141 - 152
Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Retina - metabolism | Retinal Degeneration - genetics | Mice, Inbred C57BL | Male | Retinal Degeneration - physiopathology | Retinal Ganglion Cells - metabolism | Nerve Tissue Proteins - genetics | Retinal Degeneration - metabolism | Cytoglobin - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Homozygote | Phenotype | Animals | Female | Membrane Proteins - metabolism | Mice | Eye Proteins - genetics | Mutation | Cytoglobin - metabolism | Disease Models, Animal | Index Medicus
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9. Full Text The influence of Shc proteins on life span in mice
by Ramsey, Jon J and Ramsey, Jon J and Tran, Dianna and Tran, Dianna and Giorgio, Marco and Giorgio, Marco and Griffey, Stephen M and Griffey, Stephen M and Koehne, Amanda and Koehne, Amanda and Laing, Steven T and Laing, Steven T and Taylor, Sandra L and Taylor, Sandra L and Kim, Kyoungmi and Kim, Kyoungmi and Cortopassi, Gino A and Cortopassi, Gino A and Lloyd, K. C. Kent and Lloyd, K C Kent and Hagopian, Kevork and Hagopian, Kevork and Tomilov, Alexey A and Tomilov, Alexey A and Migliaccio, Enrica and Migliaccio, Enrica and Pelicci, Pier G.iuseppe and Pelicci, Pier Giuseppe and McDonald, Roger B and McDonald, Roger B
The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1079-5006, 2014, Volume 69, Issue 10, pp. 1177 - 1185
Aging | Pathology | Longevity | Shc | Gerontology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Shc Signaling Adaptor Proteins - physiology | Animals | Src Homology 2 Domain-Containing, Transforming Protein 1 | Species Specificity | Caloric Restriction | Mice, Inbred C57BL | Animal Husbandry | Female | Male | Mice | Mice, Knockout | Proteins | Genetic aspects | Genotype & phenotype | Molecules | Life expectancy | Rodents | Index Medicus | Abridged Index Medicus | Original
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