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1. Full Text Vitamin D and cardiovascular health
by Keogh, Jennifer and Clifton, Peter
Current Opinion in Lipidology, ISSN 0957-9672, 04/2013, Volume 24, Issue 2, pp. 183 - 184
PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | D SUPPLEMENTATION | DISEASE | ENDOCRINOLOGY & METABOLISM | Biomarkers - metabolism | Hyperemia - metabolism | Cardiovascular Diseases - metabolism | Humans | Risk Factors | Vitamin D Deficiency - drug therapy | Vitamin D - pharmacology | Clinical Trials as Topic | Cardiovascular Diseases - pathology | Hyperemia - pathology | Endothelium, Vascular - metabolism | Vitamin D Deficiency - pathology | Endothelium, Vascular - pathology | Vitamin D - administration & dosage | Vitamin D - metabolism | Vitamin D Deficiency - metabolism
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2. Full Text The UK10K project identifies rare variants in health and disease
by Walter, Klaudia and Min, Josine L and Huang, Jie and Crooks, Lucy and Memari, Yasin and McCarthy, Shane and Perry, John and Xu, Changjiang and Futema, Marta and Lawson, Daniel and Iotchkova, Valentina and Schiffels, Stephan and Henicks, Auey E and Danecek, Petr and Li, Rui and Floyd, James and Wain, Louise and Barroso, Inês and Humphries, Steve and Hurles, Matthew and Zeggini, Eleftheria and Barrett, Jeffrey C and Plagnol, Vincent and Richards, Brent and Greenwood, Celia and Timpson, Nicholas and Durbin, Richard and Bala, Senduran and Clapham, Peter and Coates, Guy and Cox, Tony and Daly, Allan and Du, Yuanping and Edkins, Ted and Ellis, Peter and Flicek, Paul and Guo, Xiaosen and Guo, Xueqin and Huang, Liren and Jackson, David K and Joyce, Chris and Keane, Thomas and Kolb-Kokocinski, Anja and Langford, Cordelia and Li, Yingrui and Liang, Jieqin and Lin, Hong and Liu, Ryan and Maslen, John and Muddyman, Dawn and Quail, Michael A and Stalker, Jim and Sun, Jianping and Tian, Jing and Wang, Guangbiao and Wang, Jun and Wang, Yu and Wong, Kim and Zhang, Pingbo and Birney, Ewan and Boustred, Chris and Chen, Lu and Clement, Gail and Cocca, Massimiliano and Smith, G.D and Day, Ian N.M and Day-Williams, Aaron and Down, Thomas and Dunham, David and Evans, David M and Gaunt, Tom and Geihs, Matthias and Hart, Deborah and Howie, Bryan and Hubbard, Tim and Hysi, Pirro and Jamshidi, Yalda and Karczewski, Konrad and Kemp, John and Lachance, Genevieve and Lek, Monkol and Lopes, Margarida and MacArthur, Daniel G and Marchini, Jonathan and Mangino, Massimo and Mathieson, Iain and Metrustry, Sarah and Moayyeri, Alireza and Northstone, Kate and Panoutsopoulou, Kalliope and Paternoster, Lavinia and Quaye, Lydia and Ring, Susan and Ritchie, Graham R.S and Shihab, Hashem A and Shin, So-Youn and Small, Kerrin and Artigas, M.S and Soranzo, Nicole and Southam, Lorraine and ... and UCLEB Consortium and UK10K Consortium and The UK10K Consortium
Nature: international weekly journal of science, ISSN 0028-0836, 10/2015, Volume 526, Issue 7571, pp. 82 - 89
textabstractThe contribution of rare and low-frequency variants to human traits is largely unexplored. Here we describe insights from sequencing whole genomes... 
INCIDENTAL FINDINGS | EXOME | SNP | LOW-FREQUENCY | MULTIDISCIPLINARY SCIENCES | COMMON | APOC3 | RISK | LOCI | HERITABILITY | GENOME-WIDE ASSOCIATION | Genetics, Population | Receptors, LDL - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Disease - genetics | Health | Genomics | Humans | Molecular Sequence Annotation | Male | United Kingdom | Sequence Analysis, DNA | Genome, Human - genetics | Adiponectin - blood | Exome - genetics | Reference Standards | Genetics, Medical | Alleles | Triglycerides - blood | Female | Lipid Metabolism - genetics | Genetic Variation - genetics | Cohort Studies | Genetic research | Research | Genetic variation | Identification and classification | Health aspects | Population genetics | Proteins | Studies | Haplotypes | Obesity | Genealogy | Disease | Quality | Population | Genomes | Mutation
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3. Full Text Updated Treatment Algorithm of Pulmonary Arterial Hypertension
by Galiè, Nazzareno, MD and Corris, Paul A., MD and Frost, Adaani, MD and Girgis, Reda E., MD and Granton, John, MD and Jing, Zhi Cheng, MD and Klepetko, Walter, MD and McGoon, Michael D., MD and McLaughlin, Vallerie V., MD and Preston, Ioana R., MD and Rubin, Lewis J., MD and Sandoval, Julio, MD and Seeger, Werner, MD and Keogh, Anne, MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 25, pp. D60 - D72
The demands on a pulmonary arterial hypertension (PAH) treatment algorithm are multiple and in some ways conflicting. The treatment algorithm usually includes... 
Cardiovascular | Internal Medicine | endothelin receptor antagonists | phosphodiesterase type-5 inhibitors | prostanoids | guanylate cyclase stimulators | hypertension, pulmonary | pulmonary | lung transplantation | INHALED ILOPROST | SURROGATE END-POINTS | CARDIAC & CARDIOVASCULAR SYSTEMS | INTERNATIONAL-SOCIETY | COMBINATION THERAPY | AMBRISENTAN THERAPY | EISENMENGER-SYNDROME | CONTINUOUS INTRAVENOUS EPOPROSTENOL | HEART-LUNG TRANSPLANTATION | DOUBLE-BLIND | QUALITY-OF-LIFE | Medical colleges | Calcium channels | Algorithms | Pulmonary hypertension
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4. Full Text The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients
by Costanzo, Maria Rosa, MD and Dipchand, Anne, MD and Starling, Randall, MD and Anderson, Allen, MD and Chan, Michael, MD and Desai, Shashank, MD and Fedson, Savitri, MD and Fisher, Patrick, MD and Gonzales-Stawinski, Gonzalo, MD and Martinelli, Luigi, MD and McGiffin, David, MD and Parisi, Francesco, MD and Smith, Jon, MD and Taylor, David, MD and Meiser, Bruno, MD and Webber, Steven, MD and Baran, David, MD and Carboni, Michael, MD and Dengler, Thomas, MD and Feldman, David, MD and Frigerio, Maria, MD and Kfoury, Abdallah, MD and Kim, Daniel, MD and Kobashigawa, Jon, MD and Shullo, Michael, PharmD and Stehlik, Josef, MD and Teuteberg, Jeffrey, MD and Uber, Patricia, PharmD and Zuckermann, Andreas, MD and Hunt, Sharon, MD and Burch, Michael and Bhat, Geetha, MD and Canter, Charles, MD and Chinnock, Richard, MD and Crespo-Leiro, Marisa, MD and Delgado, Reynolds, MD and Dobbels, Fabienne, PhD and Grady, Kathleen, PhD and W, Kao, MD and Lamour, Jaqueline, MD and Parry, Gareth, MD and Patel, Jignesh, MD and Pini, Daniela, MD and Pinney, Sean, MD and Towbin, Jeffrey, MD and Wolfel, Gene, MD and Delgado, Diego, MD and Eisen, Howard, MD and Goldberg, Lee, MD and Hosenpud, Jeff, MD and Johnson, Maryl, MD and Keogh, Anne, MD and Lewis, Clive, MD and O'Connell, John, MD and Rogers, Joseph, MD and Ross, Heather, MD and Russell, Stuart, MD and Vanhaecke, Johan, MD and International Society of Heart and Lung Transplantation Guidelines
Journal of Heart and Lung Transplantation, ISSN 1053-2498, 2010, Volume 29, Issue 8, pp. 914 - 956
Institutional Affiliations Chair Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA Task Force 1 Dipchand A: Hospital for Sick Children, Toronto... 
Surgery | DOBUTAMINE STRESS ECHOCARDIOGRAPHY | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC ALLOGRAFT VASCULOPATHY | PANEL-REACTIVE ANTIBODY | MECHANICAL CIRCULATORY SUPPORT | INHIBITOR-FREE IMMUNOSUPPRESSION | HEPARIN-INDUCED THROMBOCYTOPENIA | INHALED NITRIC-OXIDE | TRANSPLANTATION | SIGNAL-AVERAGED ELECTROCARDIOGRAPHY | RESPIRATORY SYSTEM | CORONARY-ARTERY-DISEASE | EXTRACORPOREAL MEMBRANE-OXYGENATION | Perioperative Care | Postoperative Care | Societies, Medical | Humans | Graft Rejection | Heart Transplantation | International Cooperation | Tissue Donors | Postoperative Complications | Patient Selection
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5. Full Text The conservation status of the world's reptiles
by Böhm, Monika and Collen, Ben and Baillie, Jonathan E.M and Bowles, Philip and Chanson, Janice and Cox, Neil and Hammerson, Geoffrey and Hoffmann, Michael and Livingstone, Suzanne R and Ram, Mala and Rhodin, Anders G.J and Stuart, Simon N and van Dijk, Peter Paul and Young, Bruce E and Afuang, Leticia E and Aghasyan, Aram and García, Andrés and Aguilar, César and Ajtic, Rastko and Akarsu, Ferdi and Alencar, Laura R.V and Allison, Allen and Ananjeva, Natalia and Anderson, Steve and Andrén, Claes and Ariano-Sánchez, Daniel and Arredondo, Juan Camilo and Auliya, Mark and Austin, Christopher C and Avci, Aziz and Baker, Patrick J and Barreto-Lima, André F and Barrio-Amorós, César L and Basu, Dhruvayothi and Bates, Michael F and Batistella, Alexandre and Bauer, Aaron and Bennett, Daniel and Böhme, Wolfgang and Broadley, Don and Brown, Rafe and Burgess, Joseph and Captain, Ashok and Carreira, Santiago and Castañeda, Maria del Rosario and Castro, Fernando and Catenazzi, Alessandro and Cedeño-Vázquez, José R and Chapple, David G and Cheylan, Marc and Cisneros-Heredia, Diego F and Cogalniceanu, Dan and Cogger, Hal and Corti, Claudia and Costa, Gabriel C and Couper, Patrick J and Courtney, Tony and Crnobrnja-Isailovic, Jelka and Crochet, Pierre-André and Crother, Brian and Cruz, Felix and Daltry, Jennifer C and Daniels, R.J. Ranjit and Das, Indraneil and de Silva, Anslem and Diesmos, Arvin C and Dirksen, Lutz and Doan, Tiffany M and Dodd, C. Kenneth and Doody, J. Sean and Dorcas, Michael E and Duarte de Barros Filho, Jose and Egan, Vincent T and El Mouden, El Hassan and Embert, Dirk and Espinoza, Robert E and Fallabrino, Alejandro and Feng, Xie and Feng, Zhao-Jun and Fitzgerald, Lee and Flores-Villela, Oscar and França, Frederico G.R and Frost, Darrell and Gadsden, Hector and Gamble, Tony and Ganesh, S.R and Garcia, Miguel A and García-Pérez, Juan E and Gatus, Joey and Gaulke, Maren and Geniez, Philippe and Georges, Arthur and Gerlach, Justin and Goldberg, Stephen and Gonzalez, Juan-Carlos T and Gower, David J and Grant, Tandora and Greenbaum, Eli and Grieco, Cristina and Guo, Peng and ...
Biological Conservation, ISSN 0006-3207, 01/2013, Volume 157, pp. 372 - 385
Effective and targeted conservation action requires detailed information about species, their distribution, systematics and ecology as well as the distribution... 
Distribution maps | Threatened species | IUCN Red List | Lizards | Turtles | Snakes | Extinction risk | SPECIES-DIVERSITY | CLASSIFICATION | MOLECULAR PHYLOGENY | RADIATION | DISTRIBUTIONS | ENVIRONMENTAL SCIENCES | AMPHIBIANS | VERTEBRATES | GLOBAL BIODIVERSITY | ECOLOGY | BIODIVERSITY CONSERVATION | CLIMATE
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6. Full Text Molecular phylogeny and phylogeography of the Australian Diplodactylus stenodactylus (Gekkota; Reptilia) species-group based on mitochondrial and nuclear genes reveals an ancient split between Pilbara and non-Pilbara D. stenodactylus
by Pepper, Mitzy and Doughty, Paul and Keogh, J. Scott
Molecular Phylogenetics and Evolution, ISSN 1055-7903, 2006, Volume 41, Issue 3, pp. 539 - 555
There is a paucity of research on intra-specific morphological and genetic diversity in Australian arid-zone reptiles, and a number of Australian reptile... 
Reptile | Gekkonidae | Diplodactylus stenodactylus | Gekkota | Phylogeography | Biogeography | Australian arid zone | ND2 | Pilbara | 16s | RAG-1 | WESTERN-AUSTRALIA | biogeography | HETERONOTIA-BINOEI GEKKONIDAE | BIOCHEMISTRY & MOLECULAR BIOLOGY | pilbara | RAIN-FOREST | DESERT LIZARDS | reptile | DNA SEQUENCES | phylogeography | gekkota | EVOLUTIONARY BIOLOGY | EVOLUTION | GENETICS & HEREDITY | ARID-ZONE | SYSTEMATICS | DIVERSITY | EGERNIA-WHITII LACERTILIA | Geography | Lizards - classification | Genes, RAG-1 - genetics | Lizards - genetics | NADH Dehydrogenase - genetics | Phylogeny | DNA Primers - chemistry | Sequence Homology, Nucleic Acid | Animals | Polymerase Chain Reaction - veterinary | Sequence Analysis, DNA - veterinary | RNA, Ribosomal, 16S - genetics | RNA, Transfer - genetics | Australia | Genetic research
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7. Full Text Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
by Alton, Eric W F W, Prof and Armstrong, David K, MB ChB and Ashby, Deborah, Prof and Bayfield, Katie J, BSc and Bilton, Diana, Prof and Bloomfield, Emily V, BSc and Boyd, A Christopher, PhD and Brand, June, BSc and Buchan, Ruaridh, MPharm and Calcedo, Roberto, PhD and Carvelli, Paula, BN and Chan, Mario, MSc and Cheng, Seng H, PhD and Collie, D David S, MRCVS and Cunningham, Steve, MB ChB and Davidson, Heather E and Davies, Gwyneth, MBChB and Davies, Jane C, Prof and Davies, Lee A, DPhil and Dewar, Maria H, BSc and Doherty, Ann, BSc and Donovan, Jackie, PhD and Dwyer, Natalie S, RN and Elgmati, Hala I, MRCP and Featherstone, Rosanna F, BSc and Gavino, Jemyr, RN and Gea-Sorli, Sabrina, PhD and Geddes, Duncan M, Prof and Gibson, James S R, BSc and Gill, Deborah R, PhD and Greening, Andrew P, Prof and Griesenbach, Uta, Prof and Hansell, David M, Prof and Harman, Katharine, MRCPH and Higgins, Tracy E, BSc and Hodges, Samantha L, BSc and Hyde, Stephen C, DPhil and Hyndman, Laura, MSc and Innes, J Alastair, FRCPE and Jacob, Joseph, FRCR and Jones, Nancy, BPharm and Keogh, Brian F, FRCA and Limberis, Maria P, PhD and Lloyd-Evans, Paul, PhD and Maclean, Alan W, BSc and Manvell, Michelle C, BSc and McCormick, Dominique, PhD and McGovern, Michael, MRCP and McLachlan, Gerry, PhD and Meng, Cuixiang, BSc and Montero, M Angeles, MD and Milligan, Hazel, BSc and Moyce, Laura J, BSc and Murray, Gordon D, Prof and Nicholson, Andrew G, Prof and Osadolor, Tina, MSc and Parra-Leiton, Javier and Porteous, David J, Prof and Pringle, Ian A, DPhil and Punch, Emma K, BSc and Pytel, Kamila M, PhD and Quittner, Alexandra L, Prof and Rivellini, Gina and Saunders, Clare J, BSc and Scheule, Ronald K, PhD and Sheard, Sarah, FRCR and Simmonds, Nicholas J, FRCP and Smith, Keith, BSc and Smith, Stephen N, PhD and Soussi, Najwa, BSc and Soussi, Samia, BSc and Spearing, Emma J, MSc and Stevenson, Barbara J, BSc and Sumner-Jones, Stephanie G, PhD and Turkkila, Minna, BSc and Ureta, Rosa P, BN and Waller, Michael D, MRCP and Wasowicz, Marguerite Y, PhD and Wilson, James M, Prof and Wolstenholme-Hogg, Paul, PhD and UK Cystic Fibrosis Gene Therapy Co and UK Cystic Fibrosis Gene Therapy Consortium
Lancet Respiratory Medicine, The, ISSN 2213-2600, 2015, Volume 3, Issue 9, pp. 684 - 691
Summary Background Lung delivery of plasmid DNA encoding the CFTR gene complexed with a cationic liposome is a potential treatment option for patients with... 
Pulmonary/Respiratory | DNA/LIPOSOMES | EFFICACY | SAFETY | RESPIRATORY SYSTEM | DNA | COMPLEXES | MUTATION | LUNGS | NASAL EPITHELIUM | AZITHROMYCIN | AEROSOL DELIVERY | CRITICAL CARE MEDICINE | Double-Blind Method | Forced Expiratory Volume - drug effects | Cystic Fibrosis - physiopathology | Humans | Administration, Inhalation | Male | United Kingdom | Young Adult | Cystic Fibrosis - genetics | Adolescent | Cystic Fibrosis Transmembrane Conductance Regulator - administration & dosage | Adult | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Female | Liposomes | Mutation | Child | Cystic Fibrosis - drug therapy | Nebulizers and Vaporizers | Plasmids - administration & dosage | Genetic Therapy - methods
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