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1. Full Text B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study
by Haynes, Barton F and Kelsoe, Garnett and Harrison, Stephen C and Kepler, Thomas B
Nature biotechnology, ISSN 1087-0156, 05/2012, Volume 30, Issue 5, pp. 423 - 433
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Health. Pharmaceutical industry | Industrial applications and implications. Economical aspects | Biological and medical sciences | Production of active biomolecules | Vaccins | HIV-1 - metabolism | B-Lymphocytes - cytology | Cell Proliferation | Antibodies - chemistry | Humans | Neutralization Tests | Vaccines - metabolism | AIDS Vaccines - chemistry | Biotechnology - methods | Cell Lineage | Immunogenetics | HIV Antibodies - immunology | Drug Design | Epitopes - chemistry | Mutation | Binding Sites | Dimerization | Antibodies, Monoclonal - chemistry | Antibody diversity | AIDS vaccines | Physiological aspects | Product development | B cells | Research | Health aspects | Monoclonal antibodies | Antigens | Immunology | Human immunodeficiency virus--HIV | Genomics | Index Medicus
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2. Full Text Complex Antigens Drive Permissive Clonal Selection in Germinal Centers
by Kuraoka, Masayuki and Schmidt, Aaron G and Nojima, Takuya and Feng, Feng and Watanabe, Akiko and Kitamura, Daisuke and Harrison, Stephen C and Kepler, Thomas B and Kelsoe, Garnett
Immunity (Cambridge, Mass.), ISSN 1074-7613, 03/2016, Volume 44, Issue 3, pp. 542 - 552
protective antigen of B. anthracis | germinal center | B cell repertoire | clonal selection | influenza hemagglutinin | Clonal selection | Germinal center | Influenza hemagglutinin | Protective antigen of B. anthracis | Life Sciences & Biomedicine | Immunology | Science & Technology | Antibody Diversity | Clonal Selection, Antigen-Mediated | Bacterial Toxins - immunology | Germinal Center - immunology | Humans | Mice, Inbred C57BL | Antigens, Bacterial - immunology | Cells, Cultured | B-Lymphocytes - physiology | Orthomyxoviridae - metabolism | Antibody Affinity - genetics | Receptors, Antigen, B-Cell - metabolism | Hemagglutinins, Viral - immunology | Animals | Immunity, Humoral | Female | Receptors, Antigen, B-Cell - genetics | Mice | Mice, Inbred BALB C | Single-Domain Antibodies - genetics | Antigen-antibody reactions | Medical colleges | Microbiology | Influenza | Population biology | Lectins | B cells | Research institutes | Antigenic determinants | Lymphocyte receptors | Competition | Antigens | Cell culture | Genes | Rodents | Cloning | Mathematical models | Mutation | Deoxyribonucleic acid--DNA | Index Medicus
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3. Full Text Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
by Gao, Feng and Bonsignori, Mattia and Liao, Hua-Xin and Kumar, Amit and Xia, Shi-Mao and Lu, Xiaozhi and Cai, Fangping and Hwang, Kwan-Ki and Song, Hongshuo and Zhou, Tongqing and Lynch, Rebecca M and Alam, S. Munir and Moody, M. Anthony and Ferrari, Guido and Berrong, Mark and Kelsoe, Garnett and Shaw, George M and Hahn, Beatrice H and Montefiori, David C and Kamanga, Gift and Cohen, Myron S and Hraber, Peter and Kwong, Peter D and Korber, Bette T and Mascola, John R and Kepler, Thomas B and Haynes, Barton F
Cell (Cambridge), ISSN 0092-8674, 07/2014, Volume 158, Issue 3, pp. 481 - 491
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Amino Acid Sequence | env Gene Products, Human Immunodeficiency Virus - immunology | AIDS Vaccines - immunology | Models, Molecular | Molecular Sequence Data | AIDS Vaccines - chemistry | Antibodies, Neutralizing - immunology | Sequence Alignment | env Gene Products, Human Immunodeficiency Virus - genetics | B-Lymphocytes - immunology | HIV-1 - physiology | Immune Evasion | HIV Antibodies - immunology | Mutation | Viral antibodies | Antibodies | HIV (Viruses) | Index Medicus
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4. Full Text Microbial colonization influences early B-lineage development in the gut lamina propria
by Wesemann, Duane R and Portuguese, Andrew J and Meyers, Robin M and Gallagher, Michael P and Cluff-Jones, Kendra and Magee, Jennifer M and Panchakshari, Rohit A and Rodig, Scott J and Kepler, Thomas B and Alt, Frederick W
Nature (London), ISSN 0028-0836, 2013, Volume 501, Issue 7465, pp. 112 - 115
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Symbiosis | B-Lymphocytes - cytology | Immunoglobulins - immunology | Bone Marrow Cells - cytology | Weaning | Precursor Cells, B-Lymphoid - metabolism | Immunoglobulins - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - metabolism | Intestinal Mucosa - cytology | Cell Lineage | Animals | B-Lymphocytes - immunology | Intestinal Mucosa - immunology | Bone Marrow Cells - immunology | Precursor Cells, B-Lymphoid - cytology | Germ-Free Life | Mice | Gene Rearrangement, B-Lymphocyte - genetics | B-Lymphocytes - metabolism | Immunoglobulins | Genetic aspects | Research | Microbiota (Symbiotic organisms) | Properties | Microbial colonies | Spleen | Immunology | Lymphocytes | Rodents | Bone marrow | Editing | Population | Immune system | Index Medicus
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5. Full Text Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
by Zhang, Ruijun and Verkoczy, Laurent and Wiehe, Kevin and Alam, S. Munir and Nicely, Nathan I and Santra, Sampa and Bradley, Todd and Pemble, Charles W and Zhang, Jinsong and Gao, Feng and Montefiori, David C and Bouton-Verville, Hilary and Kelsoe, Garnett and Larimore, Kevin and Greenberg, Phillip D and Parks, Robert and Foulger, Andrew and Peel, Jessica N and Luo, Kan and Lu, Xiaozhi and Trama, Ashley M and Vandergrift, Nathan and Tomaras, Georgia D and Kepler, Thomas B and Moody, M. Anthony and Liao, Hua-Xin and Haynes, Barton F and Argonne National Lab. (ANL), Argonne, IL (United States)
Science translational medicine, ISSN 1946-6234, 04/2016, Volume 8, Issue 336, pp. 336ra62 - 336ra62
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Epitopes - metabolism | HIV Envelope Protein gp41 - immunology | AIDS Vaccines - immunology | Antibodies, Neutralizing - metabolism | HIV Envelope Protein gp41 - metabolism | Male | AIDS Vaccines - therapeutic use | Epitopes, B-Lymphocyte - immunology | Macaca mulatta | Immunoglobulin M - immunology | Epitopes - immunology | Immunoglobulin M - metabolism | HIV Infections - immunology | Antibodies, Neutralizing - immunology | HIV Antibodies - immunology | Mice, Mutant Strains | Female | B-Lymphocytes - metabolism | Cell Lineage - genetics | HIV Antibodies - metabolism | Animals | B-Lymphocytes - immunology | Epitopes, B-Lymphocyte - metabolism | Mice | Cell Lineage - immunology | HIV Infections - metabolism | Index Medicus | BASIC BIOLOGICAL SCIENCES
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6. Full Text Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations
by Williams, Wilton B and Zhang, Jinsong and Jiang, Chuancang and Nicely, Nathan I and Fera, Daniela and Luo, Kan and Moody, M. Anthony and Liao, Hua-Xin and Alam, S. Munir and Kepler, Thomas B and Ramesh, Akshaya and Wiehe, Kevin and Holland, James A and Bradley, Todd and Vandergrift, Nathan and Saunders, Kevin O and Parks, Robert and Foulger, Andrew and Xia, Shi-Mao and Bonsignori, Mattia and Montefiori, David C and Louder, Mark and Eaton, Amanda and Santra, Sampa and Scearce, Richard and Sutherland, Laura and Newman, Amanda and Bouton-Verville, Hilary and Bowman, Cindy and Bomze, Howard and Gao, Feng and Marshall, Dawn J and Whitesides, John F and Nie, Xiaoyan and Kelsoe, Garnett and Reed, Steven G and Fox, Christopher B and Clary, Kim and Koutsoukos, Marguerite and Franco, David and Mascola, John R and Harrison, Stephen C and Haynes, Barton F and Verkoczy, Laurent and Argonne National Lab. (ANL), Argonne, IL (United States)
Nature communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1732 - 20
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | AIDS Vaccines - immunology | Clonal Anergy | Male | Macaca mulatta | HIV Antibodies - biosynthesis | Female | B-Lymphocytes - cytology | Immunization - methods | Immune Tolerance | Models, Molecular | Mice, Transgenic | Antibodies, Neutralizing - genetics | HIV Antibodies - chemistry | Gene Knock-In Techniques | HIV-1 - immunology | Animals | B-Lymphocytes - immunology | Antibodies, Neutralizing - biosynthesis | Antibodies, Neutralizing - chemistry | Mice | HIV Antibodies - genetics | Binding Sites, Antibody | CD4 Antigens - metabolism | Cell Lineage - immunology | Immunization | Anergy | Vaccination | Antibodies | Trimers | Vaccines | Immunological tolerance | CD4 antigen | Clonal deletion | Lymphocytes B | Neutralizing | Human immunodeficiency virus--HIV | Mutation | Binding sites | Index Medicus | protein vaccines | HIV infections | peripheral tolerance | B-cell receptor | BASIC BIOLOGICAL SCIENCES
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7. Full Text Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires
by McCarthy, Kevin R and Watanabe, Akiko and Kuraoka, Masayuki and Do, Khoi T and McGee, Charles E and Sempowski, Gregory D and Kepler, Thomas B and Schmidt, Aaron G and Kelsoe, Garnett and Harrison, Stephen C and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Immunity (Cambridge, Mass.), ISSN 1074-7613, 01/2018, Volume 48, Issue 1, pp. 174 - 184.e9
B cell repertoire | clonal selection | influenza hemagglutinin | convergent evolution | Life Sciences & Biomedicine | Immunology | Science & Technology | B-Lymphocytes - immunology | Flow Cytometry | Humans | Adult | Antibodies, Viral - immunology | Female | Influenza A virus - immunology | Male | Cell Culture Techniques | Cross Reactions - immunology | Hemagglutinins, Viral - immunology | Interferometry | Influenza viruses | Medical colleges | Microbiology | Analysis | Influenza | Resveratrol | B cells | Immunity | Antigens | Immunological memory | Immunization | Memory cells | Immunoglobulins | Complementarity | Memory | Antibodies | Viruses | Infections | Exposure | Phospholipids | Lymphocytes B | Hemagglutinins | Influenza A | Affinity | Adults | Evolution & development | Binding sites | Index Medicus
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