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Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 5, pp. 444 - 450
Journal Article
Nature Genetics, ISSN 1061-4036, 06/2013, Volume 45, Issue 6, pp. 602 - 612
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7380, pp. 157 - 163
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7381, pp. 329 - 334
Retinoblastoma is an aggressive childhood cancer of the developing retina that is initiated by the biallelic loss of RB1. Tumours progress very quickly... 
ANEUPLOIDY | CELLS | GENE | TYROSINE KINASE | MCL-1 | MULTIDISCIPLINARY SCIENCES | GROWTH | TUMOR | SYK INHIBITOR | CANCER | Retinoblastoma - genetics | Protein-Tyrosine Kinases - metabolism | Genomics | Humans | Retinoblastoma - drug therapy | Gene Expression Regulation, Neoplastic | Aneuploidy | Intracellular Signaling Peptides and Proteins - metabolism | Genes, Retinoblastoma - genetics | Molecular Targeted Therapy | Retinoblastoma - pathology | Protein-Tyrosine Kinases - genetics | Cell Death - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Cell Line | Cell Survival - drug effects | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Retinoblastoma Protein - deficiency | Mutation - genetics | Sequence Analysis, DNA | Xenograft Model Antitumor Assays | Chromosomal Instability - genetics | Animals | Epigenesis, Genetic - genetics | Protein Kinase Inhibitors - therapeutic use | Retinoblastoma Protein - genetics | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Gene mutations | Development and progression | Genetic aspects | Diagnosis | Research | Retinoblastoma | Gene therapy | Health aspects | Risk factors | Studies | Human subjects | Epigenetics | DNA methylation | Genomes | Mutation | Kinases | Experiments | Chromosomes | Cancer | Children & youth | Apoptosis
Journal Article
by Holmfeldt, Linda and Wei, Lei and Diaz-Flores, Ernesto and Walsh, Michael and Zhang, Jinghui and Ding, Li and Payne-Turner, Debbie and Churchman, Michelle and Andersson, Anna and Chen, Shann-Ching and Mccastlain, Kelly and Becksfort, Jared and Ma, Jing and Wu, Gang and Patel, Samir N and Heatley, Susan L and Phillips, Letha A and Song, Guangchun and Easton, John and Parker, Matthew and Chen, Xiang and Rusch, Michael and Boggs, Kristy and Vadodaria, Bhavin and Hedlund, Erin and Drenberg, Christina and Baker, Sharyn and Pei, Deqing and Cheng, Cheng and Huether, Robert and Lu, Charles and Fulton, Robert S and Fulton, Lucinda L and Tabib, Yashodhan and Dooling, David J and Ochoa, Kerri and Minden, Mark and Lewis, Ian D and To, L. Bik and Marlton, Paula and Roberts, Andrew W and Raca, Gordana and Stock, Wendy and Neale, Geoffrey and Drexler, Hans G and Dickins, Ross A and Ellison, David W and Shurtleff, Sheila A and Pui, Ching-Hon and Ribeiro, Raul C and Devidas, Meenakshi and Carroll, Andrew J and Heerema, Nyla A and Wood, Brent and Borowitz, Michael J and Gastier-Foster, Julie M and Raimondi, Susana C and Mardis, Elaine R and Wilson, Richard K and Downing, James R and Hunger, Stephen P and Loh, Mignon L and Mullighan, Charles G and Lund University and Division of Clinical Genetics and Avdelningen för klinisk genetik and The pathogenetic mechanisms behind MLL-rearranged acute leukemia in infancy and BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation and Lunds universitet and MLL-rearrangerad leukemi hos spädbarn
Nature Genetics, ISSN 1061-4036, 03/2013, Volume 45, Issue 3, pp. 242 - 252
The genetic basis of hypodiploid acute lymphoblastic leukemia (ALL), a subtype of ALL characterized by aneuploidy and poor outcome, is unknown. Genomic... 
P53 MUTATIONS | NEUROFIBROMATOSIS TYPE-1 GENE | TRANSMEMBRANE ADAPTER | IKAROS | GENETICS & HEREDITY | JUVENILE MYELOMONOCYTIC LEUKEMIA | REGULATORY T-CELLS | MUTANT P53 | HUMAN CANCERS | HEMATOLOGIC MALIGNANCIES | CHILDHOOD | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Aneuploidy | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Tumor Suppressor Protein p53 - genetics | Ikaros Transcription Factor - genetics | Haploidy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Base Sequence | Ikaros Transcription Factor - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Signal Transduction | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Treatment Outcome | Phosphatidylinositol 3-Kinases - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Retinoblastoma Protein - genetics | Chromosome Aberrations | Cell Line, Tumor | Mice | Mutation | Care and treatment | Genomics | Physiological aspects | Genetic aspects | Research | Acute lymphocytic leukemia | Cancer | Medical research | Pediatrics | Cloning | Genetics | Genomes | Kinases | Chromosomes | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Patrick S. Schnable and Doreen Ware and Robert S. Fulton and Joshua C. Stein and Fusheng Wei and Shiran Pasternak and Chengzhi Liang and Jianwei Zhang and Lucinda Fulton and Tina A. Graves and Patrick Minx and Amy Denise Reily and Laura Courtney and Scott S. Kruchowski and Chad Tomlinson and Cindy Strong and Kim Delehaunty and Catrina Fronick and Bill Courtney and Susan M. Rock and Eddie Belter and Feiyu Du and Kyung Kim and Rachel M. Abbott and Marc Cotton and Andy Levy and Pamela Marchetto and Kerri Ochoa and Stephanie M. Jackson and Barbara Gillam and Weizu Chen and Le Yan and Jamey Higginbotham and Marco Cardenas and Jason Waligorski and Elizabeth Applebaum and Lindsey Phelps and Jason Falcone and Krishna Kanchi and Thynn Thane and Adam Scimone and Nay Thane and Jessica Henke and Tom Wang and Jessica Ruppert and Neha Shah and Kelsi Rotter and Jennifer Hodges and Elizabeth Ingenthron and Matt Cordes and Sara Kohlberg and Jennifer Sgro and Brandon Delgado and Kelly Mead and Asif Chinwalla and Shawn Leonard and Kevin Crouse and Kristi Collura and Dave Kudrna and Jennifer Currie and Ruifeng He and Angelina Angelova and Shanmugam Rajasekar and Teri Mueller and Rene Lomeli and Gabriel Scara and Ara Ko and Krista Delaney and Marina Wissotski and Georgina Lopez and David Campos and Michele Braidotti and Elizabeth Ashley and Wolfgang Golser and HyeRan Kim and Seunghee Lee and Jinke Lin and Zeljko Dujmic and Woojin Kim and Jayson Talag and Andrea Zuccolo and Chuanzhu Fan and Aswathy Sebastian and Melissa Kramer and Lori Spiegel and Lidia Nascimento and Theresa Zutavern and Beth Miller and Claude Ambroise and Stephanie Muller and Will Spooner and Apurva Narechania and Liya Ren and Sharon Wei and Sunita Kumari and Ben Faga and Michael J. Levy and Linda McMahan and Peter Van Buren and Matthew W. Vaughn and ...
Science, ISSN 0036-8075, 11/2009, Volume 326, Issue 5956, pp. 1112 - 1115
Journal Article
Nature Genetics, ISSN 1061-4036, 2016, Volume 48, Issue 12, pp. 1481 - 1489
Journal Article
by Robinson, Giles and Robinson, Giles and Parker, Matthew and Parker, Matthew and Kranenburg, Tanya A and Kranenburg, Tanya A and Lu, Charles and Lu, Charles and Chen, Xiang and Chen, Xiang and Ding, Li and Ding, Li and Phoenix, Timothy N and Phoenix, Timothy N and Hedlund, Erin and Hedlund, Erin and Wei, Lei and Wei, Lei and Zhu, Xiaoyan and Zhu, Xiaoyan and Chalhoub, Nader and Chalhoub, Nader and Baker, Suzanne J and Baker, Suzanne J and Huether, Robert and Huether, Robert and Kriwacki, Richard and Kriwacki, Richard and Curley, Natasha and Curley, Natasha and Thiruvenkatam, Radhika and Thiruvenkatam, Radhika and Wang, Jianmin and Wang, Jianmin and Wu, Gang and Wu, Gang and Rusch, Michael and Rusch, Michael and Hong, Xin and Hong, Xin and Becksfort, Jared and Becksfort, Jared and Gupta, Pankaj and Gupta, Pankaj and Ma, Jing and Ma, Jing and Easton, John and Easton, John and Vadodaria, Bhavin and Vadodaria, Bhavin and Onar-Thomas, Arzu and Onar-Thomas, Arzu and Lin, Tong and Lin, Tong and Li, Shaoyi and Li, Shaoyi and Pounds, Stanley and Pounds, Stanley and Paugh, Steven and Paugh, Steven and Zhao, David and Zhao, David and Kawauchi, Daisuke and Kawauchi, Daisuke and Roussel, Martine F and Roussel, Martine F and Finkelstein, David and Finkelstein, David and Ellison, David W and Ellison, David W and Lau, Ching C and Lau, Ching C and Bouffet, Eric and Bouffet, Eric and Hassall, Tim and Hassall, Tim and Gururangan, Sridharan and Gururangan, Sridharan and Cohn, Richard and Cohn, Richard and Fulton, Robert S and Fulton, Robert S and Fulton, Lucinda L and Fulton, Lucinda L and Dooling, David J and Dooling, David J and Ochoa, Kerri and Ochoa, Kerri and Gajjar, Amar and Gajjar, Amar and Mardis, Elaine R and Mardis, Elaine R and Wilson, Richard K and Wilson, Richard K and Downing, James R and Downing, James R and Zhang, Jinghui and Zhang, Jinghui and Gilbertson, Richard J and Gilbertson, Richard J
Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7409, pp. 43 - 48
Journal Article