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Journal Article
Archives of Toxicology, ISSN 0340-5761, 1/2013, Volume 87, Issue 1, pp. 123 - 143
Journal Article
Archives of Toxicology, ISSN 0340-5761, 7/2014, Volume 88, Issue 7, pp. 1451 - 1468
The superordinate principles governing the transcriptome response of differentiating cells exposed to drugs are still unclear. Often, it is assumed that... 
Histone deacetylase | Biomedicine | Environmental Health | Developmental toxicity | Occupational Medicine/Industrial Medicine | Embryonic stem cell | Histone modification | Pharmacology/Toxicology | Valproic acid | Biomedicine general | DESIGN PRINCIPLES | DEVELOPMENTAL NEUROTOXICITY | VALPROIC ACID | IN-VITRO | alproic acid | EMBRYONIC STEM-CELLS | GENE-EXPRESSION | SYSTEMS | TOXICOLOGY | DIFFERENTIATION | INHIBITORS | EXPOSURE | Paired Box Transcription Factors - genetics | Hydroxamic Acids - toxicity | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Histone Deacetylase Inhibitors - administration & dosage | Transcriptome | Repressor Proteins - genetics | PAX6 Transcription Factor | Homeodomain Proteins - genetics | Valproic Acid - toxicity | Gene Expression Regulation - drug effects | Acetylation - drug effects | Valproic Acid - administration & dosage | Methylation - drug effects | Time Factors | Cell Differentiation - drug effects | Histone Deacetylase Inhibitors - toxicity | Hydroxamic Acids - administration & dosage | Eye Proteins - genetics | Histones - metabolism | Drugs | Divalproex | Analysis | Genomics | Resveratrol | Methylation | Gene expression | Embryonic stem cells | Epigenetics | Side effects | Pharmacology | Toxicity | Developmental biology | Stem cells | Index Medicus | Reproductive Toxicology
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e44228
Embryonic development can be partially recapitulated in vitro by differentiating human embryonic stem cells (hESCs). Thalidomide is a developmental toxicant in... 
MULTIPLE-MYELOMA | TRANSFORMATION | VERTEBRATE LIMB DEVELOPMENT | IN-VITRO | RABBITS | MALFORMATIONS | MULTIDISCIPLINARY SCIENCES | TERATOGENICITY | MICE | EXPRESSION | DEVELOPMENTAL TOXICITY TEST | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Heart - embryology | Humans | Gene Expression Profiling | Protein Transport - drug effects | Thalidomide - pharmacology | RNA, Messenger - metabolism | Wnt Proteins - metabolism | Extremities - embryology | Dose-Response Relationship, Drug | Cell Differentiation - genetics | Glutathione Transferase - genetics | Wnt Proteins - genetics | Time Factors | RNA, Messenger - genetics | Embryonic Development - genetics | Gene Expression Regulation, Developmental - drug effects | Glutathione Transferase - metabolism | Transcription Factors - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | Transcription Factors - metabolism | Wnt Signaling Pathway - drug effects | Embryonic Stem Cells - drug effects | Wnt Signaling Pathway - genetics | Cell Differentiation - drug effects | Proteomics | Heart - drug effects | Kinetics | Embryonic Development - drug effects | Physiological aspects | Genetic aspects | Research | Genetic transcription | Cell differentiation | Embryonic stem cells | Oxidative stress | Transcription factors | Toxicity | Trafficking | Oct-4 protein | Embryo cells | Multiple myeloma | Cytotoxicity | Defects | Proteins | Embryogenesis | Toxicity testing | Fibroblasts | Biocompatibility | Physiology | Inhibition | Thalidomide | Drug dosages | Glutathione | Rabbits | Mass spectroscopy | Gene expression | Embryos | Biological activity | Embryonic growth stage | Stem cells | Teratogenicity | In vivo methods and tests | Differentiation | Mass spectrometry | Regulatory proteins
Journal Article
Archives of Toxicology, ISSN 0340-5761, 10/2016, Volume 90, Issue 10, pp. 2513 - 2529
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e89020
Journal Article
STEM CELLS, ISSN 1066-5099, 08/2014, Volume 32, Issue 8, pp. 2215 - 2228
Journal Article
Toxicology Letters, ISSN 0378-4274, 11/2014, Volume 231, Issue 1, pp. 38 - 44
Journal Article